Class information for:
Level 1: AMPK//AMP ACTIVATED PROTEIN KINASE//AICAR

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
1917 2424 51.9 92%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
262 3       AUTOPHAGY//RESVERATROL//HISTONE DEACETYLASE INHIBITOR 44558
2357 2             PEUTZ JEGHERS SYNDROME//AMPK//LKB1 4361
1917 1                   AMPK//AMP ACTIVATED PROTEIN KINASE//AICAR 2424

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 AMPK authKW 1750940 24% 24% 570
2 AMP ACTIVATED PROTEIN KINASE authKW 1277816 13% 32% 320
3 AICAR authKW 648619 4% 50% 102
4 AMP ACTIVATED PROTEIN KINASE AMPK authKW 309889 3% 37% 66
5 COMPOUND C authKW 281412 1% 62% 36
6 CELLULAR ST S GRP address 272029 1% 60% 36
7 LKB1 authKW 192092 3% 22% 69
8 ADENOSINE 5 MONOPHOSPHATE ACTIVATED PROTEIN KINASE authKW 156910 1% 35% 36
9 5 AMINOIMIDAZOLE 4 CARBOXAMIDE 1 BETA D RIBOFURANOSIDE authKW 152654 1% 61% 20
10 A 769662 authKW 141903 1% 87% 13

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Physiology 4681 16% 0% 383
2 Endocrinology & Metabolism 4456 17% 0% 421
3 Biochemistry & Molecular Biology 3649 34% 0% 832
4 Cell Biology 3221 20% 0% 485
5 Biophysics 1152 9% 0% 215
6 Peripheral Vascular Diseases 606 5% 0% 130
7 Cardiac & Cardiovascular System 309 6% 0% 139
8 Pharmacology & Pharmacy 236 8% 0% 204
9 Sport Sciences 229 3% 0% 67
10 Medicine, Research & Experimental 148 4% 0% 100

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CELLULAR ST S GRP 272029 1% 60% 36
2 ST VINCENTS MED 98633 2% 17% 46
3 HORMONE METAB UNIT 76160 1% 21% 29
4 ST VINCENTS 59116 1% 26% 18
5 CELL SIGNALLING IMMUNOL 54249 1% 17% 25
6 CELLULAR ST S GRPMRCCLIN SCI 50381 0% 100% 4
7 U1016 47417 2% 6% 60
8 UMR 8104 46090 2% 7% 53
9 COCHIN 38890 3% 4% 72
10 MOL PHYSIOL 33744 3% 4% 71

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM 19286 4% 2% 100
2 DIABETES 5957 3% 1% 76
3 CELL METABOLISM 4946 1% 2% 24
4 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 2182 5% 0% 112
5 JOURNAL OF BIOLOGICAL CHEMISTRY 2090 7% 0% 167
6 ACTA PHYSIOLOGICA 1854 1% 1% 14
7 CELLULAR SIGNALLING 1238 1% 0% 21
8 AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY 1115 1% 0% 34
9 JOURNAL OF APPLIED PHYSIOLOGY 1051 2% 0% 43
10 DIABETOLOGIA 981 1% 0% 26

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 AMPK 1750940 24% 24% 570 Search AMPK Search AMPK
2 AMP ACTIVATED PROTEIN KINASE 1277816 13% 32% 320 Search AMP+ACTIVATED+PROTEIN+KINASE Search AMP+ACTIVATED+PROTEIN+KINASE
3 AICAR 648619 4% 50% 102 Search AICAR Search AICAR
4 AMP ACTIVATED PROTEIN KINASE AMPK 309889 3% 37% 66 Search AMP+ACTIVATED+PROTEIN+KINASE+AMPK Search AMP+ACTIVATED+PROTEIN+KINASE+AMPK
5 COMPOUND C 281412 1% 62% 36 Search COMPOUND+C Search COMPOUND+C
6 LKB1 192092 3% 22% 69 Search LKB1 Search LKB1
7 ADENOSINE 5 MONOPHOSPHATE ACTIVATED PROTEIN KINASE 156910 1% 35% 36 Search ADENOSINE+5+MONOPHOSPHATE+ACTIVATED+PROTEIN+KINASE Search ADENOSINE+5+MONOPHOSPHATE+ACTIVATED+PROTEIN+KINASE
8 5 AMINOIMIDAZOLE 4 CARBOXAMIDE 1 BETA D RIBOFURANOSIDE 152654 1% 61% 20 Search 5+AMINOIMIDAZOLE+4+CARBOXAMIDE+1+BETA+D+RIBOFURANOSIDE Search 5+AMINOIMIDAZOLE+4+CARBOXAMIDE+1+BETA+D+RIBOFURANOSIDE
9 A 769662 141903 1% 87% 13 Search A+769662 Search A+769662
10 ADENOSINE MONOPHOSPHATE ACTIVATED PROTEIN KINASE 137892 2% 30% 37 Search ADENOSINE+MONOPHOSPHATE+ACTIVATED+PROTEIN+KINASE Search ADENOSINE+MONOPHOSPHATE+ACTIVATED+PROTEIN+KINASE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 STEINBERG, GR , KEMP, BE , (2009) AMPK IN HEALTH AND DISEASE.PHYSIOLOGICAL REVIEWS. VOL. 89. ISSUE 3. P. 1025 -1078 243 45% 617
2 TOWLER, MC , HARDIE, DG , (2007) AMP-ACTIVATED PROTEIN KINASE IN METABOLIC CONTROL AND INSULIN SIGNALING.CIRCULATION RESEARCH. VOL. 100. ISSUE 3. P. 328 -341 114 70% 670
3 WINDER, WW , THOMSON, DM , (2007) CELLULAR ENERGY SENSING AND SIGNALING BY AMP-ACTIVATED PROTEIN KINASE.CELL BIOCHEMISTRY AND BIOPHYSICS. VOL. 47. ISSUE 3. P. 332 -347 155 78% 75
4 VIOLLET, B , HORMAN, S , LECLERC, J , LANTIER, L , FORETZ, M , BILLAUD, M , GIRI, S , ANDREELLI, F , (2010) AMPK INHIBITION IN HEALTH AND DISEASE.CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY. VOL. 45. ISSUE 4. P. 276-295 139 66% 123
5 SHIRWANY, NA , ZOU, MH , (2014) AMPK: A CELLULAR METABOLIC AND REDOX SENSOR. A MINIREVIEW.FRONTIERS IN BIOSCIENCE-LANDMARK. VOL. 19. ISSUE . P. 447 -474 137 61% 31
6 NOVIKOVA, DS , GARABADZHIU, AV , MELINO, G , BARLEV, NA , TRIBULOVICH, VG , (2015) AMP-ACTIVATED PROTEIN KINASE: STRUCTURE, FUNCTION, AND ROLE IN PATHOLOGICAL PROCESSES.BIOCHEMISTRY-MOSCOW. VOL. 80. ISSUE 2. P. 127 -144 114 72% 11
7 SRIVASTAVA, RAK , PINKOSKY, SL , FILIPPOV, S , HANSELMAN, JC , CRAMER, CT , NEWTON, RS , (2012) AMP-ACTIVATED PROTEIN KINASE: AN EMERGING DRUG TARGET TO REGULATE IMBALANCES IN LIPID AND CARBOHYDRATE METABOLISM TO TREAT CARDIO-METABOLIC DISEASES.JOURNAL OF LIPID RESEARCH. VOL. 53. ISSUE 12. P. 2490-2514 152 54% 39
8 HARDIE, DG , ROSS, FA , HAWLEY, SA , (2012) AMPK: A NUTRIENT AND ENERGY SENSOR THAT MAINTAINS ENERGY HOMEOSTASIS.NATURE REVIEWS MOLECULAR CELL BIOLOGY. VOL. 13. ISSUE 4. P. 251 -262 59 50% 911
9 WANG, SB , SONG, P , ZOU, MH , (2012) AMP-ACTIVATED PROTEIN KINASE, STRESS RESPONSES AND CARDIOVASCULAR DISEASES.CLINICAL SCIENCE. VOL. 122. ISSUE 11-12. P. 555-573 128 57% 63
10 HARDIE, DG , SCHAFFER, BE , BRUNET, A , (2016) AMPK: AN ENERGY-SENSING PATHWAY WITH MULTIPLE INPUTS AND OUTPUTS.TRENDS IN CELL BIOLOGY. VOL. 26. ISSUE 3. P. 190 -201 50 75% 24

Classes with closest relation at Level 1


Rank Class id link
1 10287 METFORMIN//ANTIDIABETIC BIGUANIDES//PHENFORMIN
2 5790 TBC1D1//GLUCOSE TRANSPORT//GLUT4
3 17998 ACETYL COA CARBOXYLASE//SORAPHEN A//SORAPHEN
4 9462 PEUTZ JEGHERS SYNDROME//LKB1//JUVENILE POLYPOSIS
5 23435 TOPK//PBK TOPK//MELK
6 8664 PGC 1 ALPHA//MITOCHONDRIAL BIOGENESIS//PGC 1
7 28466 CELL SIGNALING METAB//SALT INDUCIBLE KINASE//SALT INDUCIBLE KINASE 1
8 8850 METFORMIN//LACTIC ACIDOSIS//BIGUANIDES
9 17960 SNRK1//HEXOSE PHOSPHORYLATION//FRUCTOKINASE
10 37064 MALONIC ACIDURIA//MALONYL COA DECARBOXYLASE DEFICIENCY//MALONYL COA DECARBOXYLASE

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