Class information for:
Level 2: PEUTZ JEGHERS SYNDROME//AMPK//LKB1

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
2357 4361 44.1 86%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
262 3       AUTOPHAGY//RESVERATROL//HISTONE DEACETYLASE INHIBITOR 44558
2357 2             PEUTZ JEGHERS SYNDROME//AMPK//LKB1 4361
1917 1                   AMPK//AMP ACTIVATED PROTEIN KINASE//AICAR 2424
9462 1                   PEUTZ JEGHERS SYNDROME//LKB1//JUVENILE POLYPOSIS 1153
23435 1                   TOPK//PBK TOPK//MELK 346
28466 1                   CELL SIGNALING METAB//SALT INDUCIBLE KINASE//SALT INDUCIBLE KINASE 1 206
33823 1                   CRONKHITE CANADA SYNDROME//ACQUIRED GASTROINTESTINAL POLYPOSIS SYNDROME//ANTI HELICOBACTER PYLORI REGIMEN 119
34277 1                   FILIFORM POLYPOSIS//PSEUDOPOLYPS//GIANT PSEUDOPOLYP 113

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PEUTZ JEGHERS SYNDROME authKW 1207868 5% 72% 239
2 AMPK authKW 1074287 14% 26% 599
3 LKB1 authKW 942731 5% 66% 205
4 AMP ACTIVATED PROTEIN KINASE authKW 727840 7% 32% 324
5 AICAR authKW 367539 2% 51% 103
6 JUVENILE POLYPOSIS authKW 295335 1% 74% 57
7 CRONKHITE CANADA SYNDROME authKW 281365 1% 93% 43
8 STK11 authKW 237735 1% 77% 44
9 AMP ACTIVATED PROTEIN KINASE AMPK authKW 210666 2% 41% 73
10 CELLULAR ST S GRP address 196091 1% 68% 41

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Cell Biology 4906 19% 0% 811
2 Biochemistry & Molecular Biology 3742 27% 0% 1189
3 Endocrinology & Metabolism 2946 11% 0% 483
4 Gastroenterology & Hepatology 2818 8% 0% 366
5 Physiology 2520 9% 0% 399
6 Oncology 1893 13% 0% 552
7 Biophysics 810 6% 0% 262
8 Genetics & Heredity 449 6% 0% 247
9 Pathology 329 3% 0% 138
10 Peripheral Vascular Diseases 290 3% 0% 138

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CELLULAR ST S GRP 196091 1% 68% 41
2 CELL SIGNALING METAB 77796 0% 65% 17
3 ST VINCENTS MED 54783 1% 17% 46
4 HORMONE METAB UNIT 45277 1% 22% 30
5 TUMOUR GENET GRP 42873 0% 88% 7
6 CELL SIGNALLING IMMUNOL 37803 1% 19% 28
7 ST VINCENTS 32843 0% 26% 18
8 POLYPOSIS REGISTRY 30837 0% 21% 21
9 U1016 29935 1% 7% 64
10 UMR 8104 28554 1% 7% 56

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM 11732 2% 2% 105
2 CELL METABOLISM 5503 1% 2% 34
3 DIABETES 3604 2% 1% 80
4 FAMILIAL CANCER 2019 0% 2% 16
5 JOURNAL OF BIOLOGICAL CHEMISTRY 1946 5% 0% 222
6 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 1573 3% 0% 131
7 CELLULAR SIGNALLING 1299 1% 1% 29
8 ACTA PHYSIOLOGICA 1171 0% 1% 15
9 ONCOTARGET 1127 1% 0% 46
10 BIOCHEMICAL JOURNAL 815 1% 0% 62

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 PEUTZ JEGHERS SYNDROME 1207868 5% 72% 239 Search PEUTZ+JEGHERS+SYNDROME Search PEUTZ+JEGHERS+SYNDROME
2 AMPK 1074287 14% 26% 599 Search AMPK Search AMPK
3 LKB1 942731 5% 66% 205 Search LKB1 Search LKB1
4 AMP ACTIVATED PROTEIN KINASE 727840 7% 32% 324 Search AMP+ACTIVATED+PROTEIN+KINASE Search AMP+ACTIVATED+PROTEIN+KINASE
5 AICAR 367539 2% 51% 103 Search AICAR Search AICAR
6 JUVENILE POLYPOSIS 295335 1% 74% 57 Search JUVENILE+POLYPOSIS Search JUVENILE+POLYPOSIS
7 CRONKHITE CANADA SYNDROME 281365 1% 93% 43 Search CRONKHITE+CANADA+SYNDROME Search CRONKHITE+CANADA+SYNDROME
8 STK11 237735 1% 77% 44 Search STK11 Search STK11
9 AMP ACTIVATED PROTEIN KINASE AMPK 210666 2% 41% 73 Search AMP+ACTIVATED+PROTEIN+KINASE+AMPK Search AMP+ACTIVATED+PROTEIN+KINASE+AMPK
10 JUVENILE POLYPOSIS SYNDROME 163517 1% 81% 29 Search JUVENILE+POLYPOSIS+SYNDROME Search JUVENILE+POLYPOSIS+SYNDROME

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 STEINBERG, GR , KEMP, BE , (2009) AMPK IN HEALTH AND DISEASE.PHYSIOLOGICAL REVIEWS. VOL. 89. ISSUE 3. P. 1025 -1078 257 48% 617
2 TOWLER, MC , HARDIE, DG , (2007) AMP-ACTIVATED PROTEIN KINASE IN METABOLIC CONTROL AND INSULIN SIGNALING.CIRCULATION RESEARCH. VOL. 100. ISSUE 3. P. 328 -341 116 72% 670
3 WINDER, WW , THOMSON, DM , (2007) CELLULAR ENERGY SENSING AND SIGNALING BY AMP-ACTIVATED PROTEIN KINASE.CELL BIOCHEMISTRY AND BIOPHYSICS. VOL. 47. ISSUE 3. P. 332 -347 158 79% 75
4 VIOLLET, B , HORMAN, S , LECLERC, J , LANTIER, L , FORETZ, M , BILLAUD, M , GIRI, S , ANDREELLI, F , (2010) AMPK INHIBITION IN HEALTH AND DISEASE.CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY. VOL. 45. ISSUE 4. P. 276-295 140 66% 123
5 NOVIKOVA, DS , GARABADZHIU, AV , MELINO, G , BARLEV, NA , TRIBULOVICH, VG , (2015) AMP-ACTIVATED PROTEIN KINASE: STRUCTURE, FUNCTION, AND ROLE IN PATHOLOGICAL PROCESSES.BIOCHEMISTRY-MOSCOW. VOL. 80. ISSUE 2. P. 127 -144 120 76% 11
6 SHIRWANY, NA , ZOU, MH , (2014) AMPK: A CELLULAR METABOLIC AND REDOX SENSOR. A MINIREVIEW.FRONTIERS IN BIOSCIENCE-LANDMARK. VOL. 19. ISSUE . P. 447 -474 140 62% 31
7 HARDIE, DG , (2011) AMP-ACTIVATED PROTEIN KINASE-AN ENERGY SENSOR THAT REGULATES ALL ASPECTS OF CELL FUNCTION.GENES & DEVELOPMENT. VOL. 25. ISSUE 18. P. 1895-1908 82 58% 485
8 SRIVASTAVA, RAK , PINKOSKY, SL , FILIPPOV, S , HANSELMAN, JC , CRAMER, CT , NEWTON, RS , (2012) AMP-ACTIVATED PROTEIN KINASE: AN EMERGING DRUG TARGET TO REGULATE IMBALANCES IN LIPID AND CARBOHYDRATE METABOLISM TO TREAT CARDIO-METABOLIC DISEASES.JOURNAL OF LIPID RESEARCH. VOL. 53. ISSUE 12. P. 2490-2514 157 55% 39
9 GAN, RY , LI, HB , (2014) RECENT PROGRESS ON LIVER KINASE B1 (LKB1): EXPRESSION, REGULATION, DOWNSTREAM SIGNALING AND CANCER SUPPRESSIVE FUNCTION.INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. VOL. 15. ISSUE 9. P. 16698 -16718 100 83% 17
10 HARDIE, DG , ROSS, FA , HAWLEY, SA , (2012) AMPK: A NUTRIENT AND ENERGY SENSOR THAT MAINTAINS ENERGY HOMEOSTASIS.NATURE REVIEWS MOLECULAR CELL BIOLOGY. VOL. 13. ISSUE 4. P. 251 -262 61 52% 911

Classes with closest relation at Level 2


Rank Class id link
1 2654 NURR1//NUR77//PGC 1 ALPHA
2 684 GLUT4//AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM//GLUCOSE TRANSPORT
3 2141 FATTY ACID SYNTHASE//LIVER X RECEPTOR//LXR
4 1220 PTEN//MTOR//COWDEN SYNDROME
5 2649 SIRT1//SIRTUINS//SIRT3
6 2612 WARBURG EFFECT//PKM2//PYRUVATE KINASE
7 1071 LYNCH SYNDROME//MICROSATELLITE INSTABILITY//HNPCC
8 827 MAMMOGRAPHIC DENSITY//BREAST DENSITY//METFORMIN
9 3108 FOXM1//FOXO1//FOXO
10 1128 AUTOPHAGY//BECLIN 1//LC3

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