Class information for:
Level 1: CELL SIGNALING METAB//SALT INDUCIBLE KINASE//SALT INDUCIBLE KINASE 1

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
28466 206 43.3 96%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
262 3       AUTOPHAGY//RESVERATROL//HISTONE DEACETYLASE INHIBITOR 44558
2357 2             PEUTZ JEGHERS SYNDROME//AMPK//LKB1 4361
28466 1                   CELL SIGNALING METAB//SALT INDUCIBLE KINASE//SALT INDUCIBLE KINASE 1 206

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CELL SIGNALING METAB address 1647624 8% 65% 17
2 SALT INDUCIBLE KINASE authKW 1524650 6% 86% 12
3 SALT INDUCIBLE KINASE 1 authKW 617624 2% 83% 5
4 CELL SIGNAL METAB address 592921 2% 100% 4
5 CRTC2 authKW 592913 4% 50% 8
6 TORC authKW 518799 3% 50% 7
7 SIK3 authKW 444690 1% 100% 3
8 CELL SIGNALING METAB DIS address 444684 3% 50% 6
9 PEPTIDE BIOL S address 404026 6% 21% 13
10 MEMBRANE SIGNALING NETWORKS address 336881 2% 45% 5

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Cell Biology 1500 44% 0% 90
2 Biochemistry & Molecular Biology 616 46% 0% 95
3 Endocrinology & Metabolism 591 21% 0% 44
4 Neurosciences 41 11% 0% 22
5 Medicine, Research & Experimental 20 5% 0% 10
6 Oncology 16 7% 0% 14
7 Physiology 14 4% 0% 8
8 Multidisciplinary Sciences 10 1% 0% 3
9 Genetics & Heredity 7 4% 0% 8
10 Developmental Biology 6 1% 0% 3

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CELL SIGNALING METAB 1647624 8% 65% 17
2 CELL SIGNAL METAB 592921 2% 100% 4
3 CELL SIGNALING METAB DIS 444684 3% 50% 6
4 PEPTIDE BIOL S 404026 6% 21% 13
5 MEMBRANE SIGNALING NETWORKS 336881 2% 45% 5
6 MED H 1 296460 1% 100% 2
7 S BIOMOL NETWORKS 213442 3% 24% 6
8 MED H1 190578 1% 43% 3
9 CONTEMPORARY HUMAN LIFE SCI 190572 3% 21% 6
10 MOL PHYSIOL CHEM 177867 3% 20% 6

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CELL METABOLISM 6513 4% 1% 8
2 ENDOCRINE RESEARCH 1737 2% 0% 4
3 SCIENCE SIGNALING 1530 2% 0% 4
4 CELLULAR SIGNALLING 844 2% 0% 5
5 NUTRITION & DIABETES 629 0% 0% 1
6 NUCLEIC ACID THERAPEUTICS 582 0% 0% 1
7 CELL DEATH & DISEASE 561 1% 0% 3
8 MOLECULAR METABOLISM 443 0% 0% 1
9 TRANSLATIONAL CANCER RESEARCH 439 0% 0% 1
10 MOLECULAR AND CELLULAR ENDOCRINOLOGY 421 2% 0% 5

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 SALT INDUCIBLE KINASE 1524650 6% 86% 12 Search SALT+INDUCIBLE+KINASE Search SALT+INDUCIBLE+KINASE
2 SALT INDUCIBLE KINASE 1 617624 2% 83% 5 Search SALT+INDUCIBLE+KINASE+1 Search SALT+INDUCIBLE+KINASE+1
3 CRTC2 592913 4% 50% 8 Search CRTC2 Search CRTC2
4 TORC 518799 3% 50% 7 Search TORC Search TORC
5 SIK3 444690 1% 100% 3 Search SIK3 Search SIK3
6 SIK1 336881 2% 45% 5 Search SIK1 Search SIK1
7 CRTC 333510 3% 38% 6 Search CRTC Search CRTC
8 SIK 302627 3% 29% 7 Search SIK Search SIK
9 SALT INDUCIBLE KINASE 2 296460 1% 100% 2 Search SALT+INDUCIBLE+KINASE+2 Search SALT+INDUCIBLE+KINASE+2
10 SALT INDUCIBLE KINASES 296460 1% 100% 2 Search SALT+INDUCIBLE+KINASES Search SALT+INDUCIBLE+KINASES

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 DU, WQ , PEI, DS , ZHENG, JN , (2016) THE DIVERSE ONCOGENIC AND TUMOR SUPPRESSOR ROLES OF SALT-INDUCIBLE KINASE (SIK) IN CANCER.EXPERT OPINION ON THERAPEUTIC TARGETS. VOL. 20. ISSUE 4. P. 477 -485 28 60% 1
2 HENRIKSSON, E , SALL, J , GORMAND, A , WASSERSTROM, S , MORRICE, NA , FRITZEN, AM , FORETZ, M , CAMPBELL, DG , SAKAMOTO, K , EKELUND, M , ET AL (2015) SIK2 REGULATES CRTCS, HDAC4 AND GLUCOSE UPTAKE IN ADIPOCYTES.JOURNAL OF CELL SCIENCE. VOL. 128. ISSUE 3. P. 472 -486 25 61% 9
3 STEWART-FITZGIBBON, R , FU, JQ , RIVERA-MOLINA, YA , BERGLUND, ED , JUSTICE, NJ , BERDEAUX, R , NIXON, M , AKHMEDOV, D , RAJENDRAN, K , MENDOZA-RODRIGUEZ, MG , ET AL (2016) SKELETAL MUSCLE SALT INDUCIBLE KINASE 1 PROMOTES INSULIN RESISTANCE IN OBESITY.MOLECULAR METABOLISM. VOL. 5. ISSUE 1. P. 34 -46 22 54% 5
4 ITOH, Y , SANOSAKA, M , FUCHINO, H , YAHARA, Y , KUMAGAI, A , TAKEMOTO, D , KAGAWA, M , DOI, J , OHTA, M , TSUMAKI, N , ET AL (2015) SALT-INDUCIBLE KINASE 3 SIGNALING IS IMPORTANT FOR THE GLUCONEOGENIC PROGRAMS IN MOUSE HEPATOCYTES.JOURNAL OF BIOLOGICAL CHEMISTRY. VOL. 290. ISSUE 29. P. 17879 -17893 26 49% 7
5 SALL, J , PETTERSSON, A , BJORK, C , HENRIKSSON, E , WASSERSTROM, S , LINDER, W , ZHOU, Y , HANSSON, O , ANDERSSON, D , EKELUND, M , ET AL (2017) SALT-INDUCIBLE KINASE 2 AND-3 ARE DOWNREGULATED IN ADIPOSE TISSUE FROM OBESE OR INSULIN-RESISTANT INDIVIDUALS: IMPLICATIONS FOR INSULIN SIGNALLING AND GLUCOSE UPTAKE IN HUMAN ADIPOCYTES.DIABETOLOGIA. VOL. 60. ISSUE 2. P. 314 -323 22 55% 0
6 SUNDBERG, TB , LIANG, YK , WU, HX , CHOI, HG , KIM, ND , SIM, T , JOHANNESSEN, L , PETRONE, A , KHOR, B , GRAHAM, DB , ET AL (2016) DEVELOPMENT OF CHEMICAL PROBES FOR INVESTIGATION OF SALT-INDUCIBLE KINASE FUNCTION IN VIVO.ACS CHEMICAL BIOLOGY. VOL. 11. ISSUE 8. P. 2105 -2111 16 76% 0
7 MCTAGUE, J , FERGUSON, M , CHIK, CL , HO, AK , (2015) THE ADRENERGIC-REGULATED CRTC1 AND CRTC2 PHOSPHORYLATION AND CELLULAR DISTRIBUTION IS INDEPENDENT OF ENDOGENOUS SIK1 IN THE MALE RAT PINEALOCYTE.MOLECULAR AND CELLULAR ENDOCRINOLOGY. VOL. 414. ISSUE C. P. 156 -167 19 48% 0
8 FINSTERWALD, C , CARRARD, A , MARTIN, JL , (2013) ROLE OF SALT-INDUCIBLE KINASE 1 IN THE ACTIVATION OF MEF2-DEPENDENT TRANSCRIPTION BY BDNF.PLOS ONE. VOL. 8. ISSUE 1. P. - 21 42% 8
9 UEBI, T , TAMURA, M , HORIKE, N , HASHIMOTO, YK , TAKEMORI, H , (2010) PHOSPHORYLATION OF THE CREB-SPECIFIC COACTIVATOR TORC2 AT SER(307) REGULATES ITS INTRACELLULAR LOCALIZATION IN COS-7 CELLS AND IN THE MOUSE LIVER.AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. VOL. 299. ISSUE 3. P. E413-E425 19 49% 14
10 LIU, Y , LI, J , JIN, DQ , TANG, XD , (2009) REGULATION OF TORC-CREB COMPLEX BY SALT-INDUCIBLE KINASES: IMPLICATIONS IN HYPERTENSION AND DIABETES MELLITUS.PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS. VOL. 36. ISSUE 3. P. 274-279 18 53% 0

Classes with closest relation at Level 1


Rank Class id link
1 8733 CREM//CREB//ICER
2 16802 MEF2C//MEF2//MEF2D
3 23435 TOPK//PBK TOPK//MELK
4 9462 PEUTZ JEGHERS SYNDROME//LKB1//JUVENILE POLYPOSIS
5 32852 POLYPYRIMIDINE TRACT BINDING PROTEIN ASSOCIATED SPLICING FACTOR//P54NRB//NONO
6 8664 PGC 1 ALPHA//MITOCHONDRIAL BIOGENESIS//PGC 1
7 10728 STEROIDOGENIC ACUTE REGULATORY PROTEIN//STAR//STEROIDOGENIC ACUTE REGULATORY PROTEIN STAR
8 1917 AMPK//AMP ACTIVATED PROTEIN KINASE//AICAR
9 24101 MIXED LINEAGE KINASE//RPM 1//DLK
10 8936 FOXO1//FOXO//FOXO3A

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