Class information for:
Level 3: AUTOPHAGY//RESVERATROL//HISTONE DEACETYLASE INHIBITOR

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
262 44558 49.2 90%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
262 3       AUTOPHAGY//RESVERATROL//HISTONE DEACETYLASE INHIBITOR 44558
1128 2             AUTOPHAGY//BECLIN 1//LC3 9655
1220 2             PTEN//MTOR//COWDEN SYNDROME 9128
1531 2             HISTONE DEACETYLASE INHIBITOR//HISTONE DEACETYLASE//HDAC INHIBITOR 7464
2255 2             RESVERATROL//PTEROSTILBENE//TRANS RESVERATROL 4690
2357 2             PEUTZ JEGHERS SYNDROME//AMPK//LKB1 4361
2649 2             SIRT1//SIRTUINS//SIRT3 3472
2654 2             NURR1//NUR77//PGC 1 ALPHA 3465
3108 2             FOXM1//FOXO1//FOXO 2323

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 AUTOPHAGY authKW 1032530 9% 37% 4050
2 RESVERATROL authKW 869748 5% 53% 2387
3 HISTONE DEACETYLASE INHIBITOR authKW 292891 2% 55% 780
4 SIRT1 authKW 289781 2% 56% 753
5 HISTONE DEACETYLASE authKW 273933 2% 48% 837
6 SIRTUINS authKW 249653 1% 65% 560
7 MTOR authKW 220251 2% 30% 1099
8 PTEN authKW 216393 2% 35% 906
9 AMPK authKW 190388 2% 35% 809
10 BECLIN 1 authKW 179827 1% 67% 395

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Cell Biology 89074 24% 1% 10698
2 Oncology 47304 18% 1% 8214
3 Biochemistry & Molecular Biology 43569 29% 1% 12803
4 Chemistry, Medicinal 7215 5% 1% 2015
5 Endocrinology & Metabolism 4994 5% 1% 2377
6 Biophysics 4216 5% 1% 2067
7 Genetics & Heredity 3452 5% 0% 2283
8 Medicine, Research & Experimental 3420 4% 0% 1991
9 Pharmacology & Pharmacy 2904 7% 0% 3310
10 Physiology 1763 3% 0% 1434

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 MED 28160 29% 1% 12918
2 AUTOPHAGY 22750 0% 65% 51
3 CELLULAR ST S GRP 20064 0% 70% 42
4 U756 13950 0% 66% 31
5 ANAT CELL DEV BIOL 13829 0% 41% 50
6 PATHOL 13700 8% 1% 3430
7 CANC 13051 3% 2% 1251
8 PROT PHOSPHORYLAT UNIT 11643 0% 20% 86
9 PHARMACOL 11535 4% 1% 1853
10 PAUL F GLENN S BIOL MECH AGING 11492 0% 54% 31

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 AUTOPHAGY 339633 2% 57% 869
2 JOURNAL OF BIOLOGICAL CHEMISTRY 14221 4% 1% 1951
3 ONCOTARGET 12340 1% 4% 486
4 CELL METABOLISM 11460 0% 11% 158
5 MOLECULAR CANCER THERAPEUTICS 8715 1% 6% 233
6 ONCOGENE 8356 1% 3% 493
7 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 6898 2% 1% 910
8 COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY SERIES 6378 0% 4% 221
9 CELL DEATH & DISEASE 6342 0% 6% 151
10 CLINICAL CANCER RESEARCH 5627 1% 3% 369

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class		 LCSH search Wikipedia search
1 AUTOPHAGY 1032530 9% 37% 4050 Search AUTOPHAGY Search AUTOPHAGY
2 RESVERATROL 869748 5% 53% 2387 Search RESVERATROL Search RESVERATROL
3 HISTONE DEACETYLASE INHIBITOR 292891 2% 55% 780 Search HISTONE+DEACETYLASE+INHIBITOR Search HISTONE+DEACETYLASE+INHIBITOR
4 SIRT1 289781 2% 56% 753 Search SIRT1 Search SIRT1
5 HISTONE DEACETYLASE 273933 2% 48% 837 Search HISTONE+DEACETYLASE Search HISTONE+DEACETYLASE
6 SIRTUINS 249653 1% 65% 560 Search SIRTUINS Search SIRTUINS
7 MTOR 220251 2% 30% 1099 Search MTOR Search MTOR
8 PTEN 216393 2% 35% 906 Search PTEN Search PTEN
9 AMPK 190388 2% 35% 809 Search AMPK Search AMPK
10 BECLIN 1 179827 1% 67% 395 Search BECLIN+1 Search BECLIN+1

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 CHEN, XM , CHEN, YH , CHEN, YG , CIRONE, M , COCCO, T , CODOGNO, P , COERS, J , COHEN, EEW , COLECCHIA, D , COLETTO, L , ET AL (2016) GUIDELINES FOR THE USE AND INTERPRETATION OF ASSAYS FOR MONITORING AUTOPHAGY (3RD EDITION).AUTOPHAGY. VOL. 12. ISSUE 1. P. 1 -222 1108 56% 97
2 FISHER, EA , FISHER, PB , FLAJOLET, M , FON, EA , FORNAI, F , FORTUNATO, F , FOTEDAR, R , FOWLER, DH , FOX, HS , FRANCO, R , ET AL (2012) GUIDELINES FOR THE USE AND INTERPRETATION OF ASSAYS FOR MONITORING AUTOPHAGY.AUTOPHAGY. VOL. 8. ISSUE 4. P. 445 -544 517 65% 1034
3 RAVIKUMAR, B , SARKAR, S , DAVIES, JE , FUTTER, M , GARCIA-ARENCIBIA, M , GREEN-THOMPSON, ZW , JIMENEZ-SANCHEZ, M , KOROLCHUK, VI , LICHTENBERG, M , LUO, SQ , ET AL (2010) REGULATION OF MAMMALIAN AUTOPHAGY IN PHYSIOLOGY AND PATHOPHYSIOLOGY.PHYSIOLOGICAL REVIEWS. VOL. 90. ISSUE 4. P. 1383 -1435 341 60% 618
4 MORRIS, BJ , (2013) SEVEN SIRTUINS FOR SEVEN DEADLY DISEASES OF AGING.FREE RADICAL BIOLOGY AND MEDICINE. VOL. 56. ISSUE . P. 133 -171 405 71% 84
5 FENG, YC , HE, D , YAO, ZY , KLIONSKY, DJ , (2014) THE MACHINERY OF MACROAUTOPHAGY.CELL RESEARCH. VOL. 24. ISSUE 1. P. 24-41 159 96% 244
6 WESSELBORG, S , STORK, B , (2015) AUTOPHAGY SIGNAL TRANSDUCTION BY ATG PROTEINS: FROM HIERARCHIES TO NETWORKS.CELLULAR AND MOLECULAR LIFE SCIENCES. VOL. 72. ISSUE 24. P. 4721 -4757 326 85% 11
7 RUBINSZTEIN, DC , CODOGNO, P , LEVINE, B , (2012) AUTOPHAGY MODULATION AS A POTENTIAL THERAPEUTIC TARGET FOR DIVERSE DISEASES.NATURE REVIEWS DRUG DISCOVERY. VOL. 11. ISSUE 9. P. 709 -U84 194 79% 395
8 HE, CC , KLIONSKY, DJ , (2009) REGULATION MECHANISMS AND SIGNALING PATHWAYS OF AUTOPHAGY.ANNUAL REVIEW OF GENETICS. VOL. 43. ISSUE . P. 67-93 148 87% 1154
9 TOME-CARNEIRO, J , LARROSA, M , GONZALEZ-SARRIAS, A , TOMAS-BARBERAN, FA , GARCIA-CONESA, MT , ESPIN, JC , (2013) RESVERATROL AND CLINICAL TRIALS: THE CROSSROAD FROM IN VITRO STUDIES TO HUMAN EVIDENCE.CURRENT PHARMACEUTICAL DESIGN. VOL. 19. ISSUE 34. P. 6064 -6093 252 83% 97
10 LAPLANTE, M , SABATINI, DM , (2012) MTOR SIGNALING IN GROWTH CONTROL AND DISEASE.CELL. VOL. 149. ISSUE 2. P. 274-293 107 62% 2214

Classes with closest relation at Level 3


Rank Class id link
1 563 DNA METHYLATION//EPIGENETICS//METHYLATION
2 447 TCTP//TRANSLATIONALLY CONTROLLED TUMOR PROTEIN//GENETIC EPIDEMIOLOGY
3 204 PROTEASOME//UBIQUITIN//UNFOLDED PROTEIN RESPONSE
4 441 TRAIL//SURVIVIN//APOPTOSIS
5 269 CELL BIOLOGY//CAVEOLIN 1//CAVEOLAE
6 408 CHIM BIOINORGAN//POLO SCI//CARBONIC ANHYDRASE
7 364 TELOMERASE//TELOMERE//C ELEGANS
8 103 O GLCNACYLATION//O GLCNAC TRANSFERASE//O GLCNACASE
9 66 LEPTIN//ADIPONECTIN//ENDOCRINOLOGY & METABOLISM
10 584 POMPE DISEASE//PIN1//CYCLOPHILIN

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