Class information for:
Level 1: TOPK//PBK TOPK//MELK

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
23435 346 39.1 93%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
262 3       AUTOPHAGY//RESVERATROL//HISTONE DEACETYLASE INHIBITOR 44558
2357 2             PEUTZ JEGHERS SYNDROME//AMPK//LKB1 4361
23435 1                   TOPK//PBK TOPK//MELK 346

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 TOPK authKW 1556756 6% 84% 21
2 PBK TOPK authKW 1323777 4% 100% 15
3 MELK authKW 1159300 5% 77% 17
4 ARK5 authKW 802288 3% 91% 10
5 PDZ BINDING KINASE authKW 794266 3% 100% 9
6 MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE authKW 441259 1% 100% 5
7 MARK4 authKW 367714 1% 83% 5
8 MICROTUBULE AFFINITY REGULATING KINASE 4 authKW 353007 1% 100% 4
9 PBK authKW 317702 2% 60% 6
10 NUAK1 authKW 275783 1% 63% 5

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Oncology 1309 33% 0% 113
2 Cell Biology 1108 30% 0% 103
3 Biochemistry & Molecular Biology 692 39% 0% 134
4 Genetics & Heredity 146 10% 0% 34
5 Developmental Biology 136 4% 0% 15
6 Biophysics 74 6% 0% 22
7 Cell & Tissue Engineering 25 1% 0% 3
8 Medicine, Research & Experimental 16 4% 0% 13
9 Pathology 11 2% 0% 8
10 Biotechnology & Applied Microbiology 9 4% 0% 13

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CANC PHYSIOL PROJECT 102476 2% 19% 6
2 BLOOD MARROW TRANSPLANT TEAM 88252 0% 100% 1
3 CELL BIOL PHYSIOL INTERNAL MED 88252 0% 100% 1
4 CELL CYCLE GRPSFR BIOSIT 88252 0% 100% 1
5 CELL DEV BIOL MEDABRAMSON FAMILY CAN 88252 0% 100% 1
6 CEREBRALVASC DIS 88252 0% 100% 1
7 CLIN BIOCHEM MED GENET 88252 0% 100% 1
8 CORE PHARMACOL 88252 0% 100% 1
9 DERMATOLBANTING 88252 0% 100% 1
10 EA TEURS RIS VASC MODELES CLIN BIOL 3670 88252 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ONCOTARGET 2313 5% 0% 18
2 CANCER SCIENCE 1217 2% 0% 7
3 ONCOGENE 687 3% 0% 12
4 INTERNATIONAL JOURNAL OF ONCOLOGY 581 2% 0% 8
5 CELL CYCLE 533 1% 0% 2
6 BIOLOGY OPEN 418 1% 0% 2
7 JOURNAL OF BIOLOGICAL CHEMISTRY 359 8% 0% 26
8 BIOLOGY OF THE CELL 314 1% 0% 3
9 BRAIN TUMOR PATHOLOGY 268 0% 0% 1
10 CANCER RESEARCH 257 3% 0% 11

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 TOPK 1556756 6% 84% 21 Search TOPK Search TOPK
2 PBK TOPK 1323777 4% 100% 15 Search PBK+TOPK Search PBK+TOPK
3 MELK 1159300 5% 77% 17 Search MELK Search MELK
4 ARK5 802288 3% 91% 10 Search ARK5 Search ARK5
5 PDZ BINDING KINASE 794266 3% 100% 9 Search PDZ+BINDING+KINASE Search PDZ+BINDING+KINASE
6 MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE 441259 1% 100% 5 Search MATERNAL+EMBRYONIC+LEUCINE+ZIPPER+KINASE Search MATERNAL+EMBRYONIC+LEUCINE+ZIPPER+KINASE
7 MARK4 367714 1% 83% 5 Search MARK4 Search MARK4
8 MICROTUBULE AFFINITY REGULATING KINASE 4 353007 1% 100% 4 Search MICROTUBULE+AFFINITY+REGULATING+KINASE+4 Search MICROTUBULE+AFFINITY+REGULATING+KINASE+4
9 PBK 317702 2% 60% 6 Search PBK Search PBK
10 NUAK1 275783 1% 63% 5 Search NUAK1 Search NUAK1

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 LEI, B , QI, WJ , ZHAO, YF , LI, YM , LIU, SG , XU, XY , ZHI, C , WAN, LY , SHEN, H , (2015) PBK/TOPK EXPRESSION CORRELATES WITH MUTANT P53 AND AFFECTS PATIENTS' PROGNOSIS AND CELL PROLIFERATION AND VIABILITY IN LUNG ADENOCARCINOMA.HUMAN PATHOLOGY. VOL. 46. ISSUE 2. P. 217 -224 25 74% 3
2 LI, S , LI, ZY , GUO, T , XING, XF , CHENG, XJ , DU, H , WEN, XZ , JI, JF , (2016) MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE SERVES AS A POOR PROGNOSIS MARKER AND THERAPEUTIC TARGET IN GASTRIC CANCER.ONCOTARGET. VOL. 7. ISSUE 5. P. 6266 -6280 20 67% 4
3 JIANG, PF , ZHANG, DL , (2013) MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE (MELK): A NOVEL REGULATOR IN CELL CYCLE CONTROL, EMBRYONIC DEVELOPMENT, AND CANCER.INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. VOL. 14. ISSUE 11. P. 21551-21560 30 55% 9
4 XIAO, JJ , DUAN, QH , WANG, Z , YAN, W , SUN, HM , XUE, PP , FAN, XM , ZENG, XY , CHEN, J , SHAO, C , ET AL (2016) PHOSPHORYLATION OF TOPK AT Y74, Y272 BY SRC INCREASES THE STABILITY OF TOPK AND PROMOTES TUMORIGENESIS OF COLON CANCER.ONCOTARGET. VOL. 7. ISSUE 17. P. 24483 -24494 24 60% 0
5 DONG, CM , TANG, X , XIE, Y , ZOU, QW , YANG, X , ZHOU, H , (2016) THE CRYSTAL STRUCTURE OF AN INACTIVE DIMER OF PDZ-BINDING KINASE.BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. VOL. 476. ISSUE 4. P. 586 -593 21 68% 0
6 SUN, XL , GAO, L , CHIEN, HY , LI, WC , ZHAO, JJ , (2013) THE REGULATION AND FUNCTION OF THE NUAK FAMILY.JOURNAL OF MOLECULAR ENDOCRINOLOGY. VOL. 51. ISSUE 2. P. R15-R22 26 51% 12
7 MARIE, SKN , OBA-SHINJO, SM , DA SILVA, R , GIMENEZ, M , REIS, GN , TASSAN, JP , ROSA, JC , UNO, M , (2016) STATHMIN INVOLVEMENT IN THE MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE PATHWAY IN GLIOBLASTOMA.PROTEOME SCIENCE. VOL. 14. ISSUE . P. - 24 48% 1
8 BEKE, L , KIG, C , LINDERS, JTM , BOENS, S , BOECKX, A , VAN HEERDE, E , PARADE, M , DE BONDT, A , VAN DEN WYNGAERT, I , BASHIR, T , ET AL (2015) MELK-T1, A SMALL-MOLECULE INHIBITOR OF PROTEIN KINASE MELK, DECREASES DNA-DAMAGE TOLERANCE IN PROLIFERATING CANCER CELLS.BIOSCIENCE REPORTS. VOL. 35. ISSUE . P. - 22 56% 1
9 CAO, LS , WANG, J , CHEN, YL , DENG, HT , WANG, ZX , WU, JW , (2013) STRUCTURAL BASIS FOR THE REGULATION OF MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE.PLOS ONE. VOL. 8. ISSUE 7. P. - 24 53% 4
10 DU, T , QU, Y , LI, JF , LI, H , SU, LP , ZHOU, Q , YAN, M , LI, C , ZHU, ZG , LIU, BY , (2014) MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE ENHANCES GASTRIC CANCER PROGRESSION VIA THE FAK/PAXILLIN PATHWAY.MOLECULAR CANCER. VOL. 13. ISSUE . P. - 22 51% 15

Classes with closest relation at Level 1


Rank Class id link
1 28466 CELL SIGNALING METAB//SALT INDUCIBLE KINASE//SALT INDUCIBLE KINASE 1
2 9462 PEUTZ JEGHERS SYNDROME//LKB1//JUVENILE POLYPOSIS
3 1917 AMPK//AMP ACTIVATED PROTEIN KINASE//AICAR
4 37546 KIAA0101//NS5ATP9//OEATC 1
5 22795 ASK1//PP5//PROTEIN PHOSPHATASE 5
6 11431 CRUMBS//SCRIBBLE//ERBIN
7 37394 SCUBE1//SIGNAL PEPTIDE CUB EGF DOMAIN CONTAINING PROTEIN 1//SCUBE3
8 24888 CANC VACCINE DEV//INNOVAT CANC THER Y//PERSONALIZED PEPTIDE VACCINE
9 19947 FOXM1//FORKHEAD BOX M1//FORKHEAD BOX PROTEIN M1
10 28520 MAP4K4//TNIK//MST3

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