Class information for:
Level 1: MAP4K4//TNIK//MST3

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
28520 205 41.4 94%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
204 3       PROTEASOME//UBIQUITIN//UNFOLDED PROTEIN RESPONSE 52492
1195 2             JNK//ERK5//MAP KINASE 9252
28520 1                   MAP4K4//TNIK//MST3 205

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MAP4K4 authKW 1258646 6% 65% 13
2 TNIK authKW 680922 4% 57% 8
3 MST3 authKW 670287 3% 75% 6
4 STE20 authKW 563215 5% 34% 11
5 STE20 LIKE KINASE authKW 531973 2% 71% 5
6 MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE KINASE 4 authKW 446860 1% 100% 3
7 SLK authKW 413755 2% 56% 5
8 GERMINAL CENTER KINASES authKW 297906 1% 100% 2
9 LOSK authKW 297906 1% 100% 2
10 TRAF2 AND NCK INTERACTING KINASE authKW 297906 1% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Cell Biology 938 35% 0% 72
2 Biochemistry & Molecular Biology 915 55% 0% 113
3 Oncology 137 15% 0% 31
4 Biophysics 72 8% 0% 16
5 Chemistry, Medicinal 40 5% 0% 10
6 Genetics & Heredity 35 7% 0% 14
7 Developmental Biology 33 3% 0% 6
8 Pathology 13 3% 0% 6
9 Physiology 6 3% 0% 6
10 Medicine, Research & Experimental 4 3% 0% 6

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 AFFILIATED TUMOR HOSP XIANG YA MED 148953 0% 100% 1
2 BIOICHEM MICROBIOL IMMUNOL 148953 0% 100% 1
3 BIOMARKER PERSONALIZED MED GRP 148953 0% 100% 1
4 CNRSINSERMU1019 UMR 8204 INFECT IMMUN LIL 148953 0% 100% 1
5 CVMED TARGET EXPLORAT 148953 0% 100% 1
6 DIAGNOST TREATMENT TB 148953 0% 100% 1
7 EXPT IMMUNOL BRANCH BRANCHES 148953 0% 100% 1
8 INSERMUMR S 1155 148953 0% 100% 1
9 MED BIOL MOL KANAZAWA KU 148953 0% 100% 1
10 MINIST HLTHMINIST EDUC CARCINOGENESIS 148953 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 HUMAN CELL 3115 1% 1% 2
2 SKELETAL MUSCLE 3083 1% 1% 2
3 JOURNAL OF BIOLOGICAL CHEMISTRY 1557 20% 0% 40
4 CELL ADHESION & MIGRATION 1009 1% 0% 2
5 ONCOGENESIS 564 0% 0% 1
6 AGING AND DISEASE 562 0% 0% 1
7 ONCOGENE 517 4% 0% 8
8 CELL AND BIOSCIENCE 454 0% 0% 1
9 ACS MEDICINAL CHEMISTRY LETTERS 430 1% 0% 2
10 AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY 357 2% 0% 4

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 MAP4K4 1258646 6% 65% 13 Search MAP4K4 Search MAP4K4
2 TNIK 680922 4% 57% 8 Search TNIK Search TNIK
3 MST3 670287 3% 75% 6 Search MST3 Search MST3
4 STE20 563215 5% 34% 11 Search STE20 Search STE20
5 STE20 LIKE KINASE 531973 2% 71% 5 Search STE20+LIKE+KINASE Search STE20+LIKE+KINASE
6 MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE KINASE 4 446860 1% 100% 3 Search MITOGEN+ACTIVATED+PROTEIN+KINASE+KINASE+KINASE+KINASE+4 Search MITOGEN+ACTIVATED+PROTEIN+KINASE+KINASE+KINASE+KINASE+4
7 SLK 413755 2% 56% 5 Search SLK Search SLK
8 GERMINAL CENTER KINASES 297906 1% 100% 2 Search GERMINAL+CENTER+KINASES Search GERMINAL+CENTER+KINASES
9 LOSK 297906 1% 100% 2 Search LOSK Search LOSK
10 TRAF2 AND NCK INTERACTING KINASE 297906 1% 100% 2 Search TRAF2+AND+NCK+INTERACTING+KINASE Search TRAF2+AND+NCK+INTERACTING+KINASE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 GAO, X , GAO, CX , LIU, GX , HU, J , (2016) MAP4K4: AN EMERGING THERAPEUTIC TARGET IN CANCER.CELL AND BIOSCIENCE. VOL. 6. ISSUE . P. - 36 67% 0
2 VIRBASIUS, JV , CZECH, MP , (2016) MAP4K4 SIGNALING NODES IN METABOLIC AND CARDIOVASCULAR DISEASES.TRENDS IN ENDOCRINOLOGY AND METABOLISM. VOL. 27. ISSUE 7. P. 484 -492 26 45% 5
3 AL-ZAHRANI, KN , SEKHON, P , TESSIER, DR , YOCKELL-LELIEVRE, J , PRYCE, BR , BARON, KD , HOWE, GA , SRIRAM, RK , DANIEL, K , MCKAY, M , ET AL (2014) ESSENTIAL ROLE FOR THE SLK PROTEIN KINASE IN EMBRYOGENESIS AND PLACENTAL TISSUE DEVELOPMENT.DEVELOPMENTAL DYNAMICS. VOL. 243. ISSUE 5. P. 640-651 21 58% 1
4 NDUBAKU, CO , CRAWFORD, TD , CHEN, HF , BOGGS, JW , DROBNICK, J , HARRIS, SF , JESUDASON, R , MCNAMARA, E , NONOMIYA, J , SAMBRONE, A , ET AL (2015) STRUCTURE-BASED DESIGN OF GNE-495, A POTENT AND SELECTIVE MAP4K4 INHIBITOR WITH EFFICACY IN RETINAL ANGIOGENESIS.ACS MEDICINAL CHEMISTRY LETTERS. VOL. 6. ISSUE 8. P. 913 -918 14 64% 8
5 LUHOVY, AY , JABERI, A , PAPILLON, J , GUILLEMETTE, J , CYBULSKY, AV , (2012) REGULATION OF THE STE20-LIKE KINASE, SLK INVOLVEMENT OF ACTIVATION SEGMENT PHOSPHORYLATION.JOURNAL OF BIOLOGICAL CHEMISTRY. VOL. 287. ISSUE 8. P. 5446-5458 22 48% 4
6 DELPIRE, E , (2009) THE MAMMALIAN FAMILY OF STERILE 20P-LIKE PROTEIN KINASES.PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY. VOL. 458. ISSUE 5. P. 953 -967 33 28% 44
7 CYBULSKY, AV , GUILLEMETTE, J , PAPILLON, J , (2016) STE20-LIKE KINASE, SLK, ACTIVATES THE HEAT SHOCK FACTOR 1-HSP70 PATHWAY.BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH. VOL. 1863. ISSUE 9. P. 2147 -2155 21 40% 0
8 AL-ZAHRANI, KN , BARON, KD , SABOURIN, LA , (2013) STE20-LIKE KINASE SLK, AT THE CROSSROADS A MATTER OF LIFE AND DEATH.CELL ADHESION & MIGRATION. VOL. 7. ISSUE 1. P. 1 -10 25 34% 10
9 STORBECK, CJ , AL-ZAHRANI, KN , SRIRAM, R , KAWESA, S , O'REILLY, P , DANIEL, K , MCKAY, M , KOTHARY, R , TSILFIDIS, C , SABOURIN, LA , (2013) DISTINCT ROLES FOR STE20-LIKE KINASE SLK IN MUSCLE FUNCTION AND REGENERATION.SKELETAL MUSCLE. VOL. 3. ISSUE . P. - 22 37% 1
10 CRAWFORD, TD , NDUBAKU, CO , CHEN, HF , BOGGS, JW , BRAVO, BJ , DELATORRE, K , GIANNETTI, AM , GOULD, SE , HARRIS, SF , MAGNUSON, SR , ET AL (2014) DISCOVERY OF SELECTIVE 4-AMINO-PYRIDOPYRIMIDINE INHIBITORS OF MAP4K4 USING FRAGMENT-BASED LEAD IDENTIFICATION AND OPTIMIZATION.JOURNAL OF MEDICINAL CHEMISTRY. VOL. 57. ISSUE 8. P. 3484 -3493 13 52% 11

Classes with closest relation at Level 1


Rank Class id link
1 5305 YAP//HIPPO PATHWAY//TAZ
2 13788 SLP 76//ADAP//SECT LYMPHOCYTE SIGNALING
3 11502 PAK1//P21 ACTIVATED KINASE//PAK4
4 5457 JNK//MKK4//C JUN N TERMINAL KINASE
5 24101 MIXED LINEAGE KINASE//RPM 1//DLK
6 17952 TRAF4//TRAF6//TRAF2
7 6141 WNK//WNK4//WNK KINASE
8 29741 COMPARAT PSYCHOL BEHAV BIOL//BEHAV BIOL COMPARAT PSYCHOL//3 APMPA
9 11178 RAP1//EPAC//EPAC1
10 11497 POLO LIKE KINASE 1//PLK1//POLO LIKE KINASE

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