Class information for:
Level 1: PAK1//P21 ACTIVATED KINASE//PAK4

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
11502 977 47.9 94%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
269 3       CELL BIOLOGY//CAVEOLIN 1//CAVEOLAE 44007
536 2             X LINKED AGAMMAGLOBULINEMIA//BTK//SH2 DOMAIN 14793
11502 1                   PAK1//P21 ACTIVATED KINASE//PAK4 977

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PAK1 authKW 1273818 8% 54% 75
2 P21 ACTIVATED KINASE authKW 1106741 7% 54% 66
3 PAK4 authKW 964358 4% 86% 36
4 PAK authKW 586172 5% 38% 49
5 GIT1 authKW 423896 2% 59% 23
6 PAK5 authKW 315129 1% 92% 11
7 P21 ACTIVATED KINASE 1 authKW 292983 2% 63% 15
8 G PROTEIN COUPLED RECEPTOR KINASE INTERACTING PROTEIN 1 authKW 253145 1% 90% 9
9 P21 ACTIVATED KINASE 4 authKW 250021 1% 100% 8
10 PAK6 authKW 222240 1% 89% 8

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Cell Biology 5716 39% 0% 385
2 Biochemistry & Molecular Biology 2725 45% 0% 437
3 Oncology 1378 21% 0% 204
4 Developmental Biology 85 2% 0% 22
5 Biophysics 70 4% 0% 41
6 Genetics & Heredity 41 4% 0% 41
7 Medicine, Research & Experimental 39 4% 0% 35
8 Chemistry, Medicinal 31 2% 0% 24
9 Hematology 24 2% 0% 23
10 Physiology 18 3% 0% 25

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CELL ADHES UNIT 114579 1% 33% 11
2 BIOL SCI MC 2460 70317 0% 75% 3
3 SECT VERTEBRATE DEV 70317 0% 75% 3
4 UNIT CELL ADHES 62505 0% 100% 2
5 SGSK GRP 45453 0% 36% 4
6 BREAST CANC THEME 41669 0% 67% 2
7 IMMUNOL IMM14 41669 0% 67% 2
8 MOL CELL BIOL GLAXO IMCB GRP 41669 0% 67% 2
9 SIGNALING DISORDER 35712 0% 29% 4
10 GLAXO IMCB GRP 35507 1% 23% 5

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF BIOLOGICAL CHEMISTRY 3005 13% 0% 123
2 MOLECULAR AND CELLULAR BIOLOGY 2193 4% 0% 40
3 CELLULAR SIGNALLING 1590 2% 0% 15
4 JOURNAL OF CELL SCIENCE 1581 3% 0% 26
5 ONCOGENE 1315 3% 0% 28
6 ONCOTARGET 987 2% 0% 20
7 BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH 817 1% 0% 11
8 RECEPTORS & SIGNAL TRANSDUCTION 779 0% 3% 1
9 MOLECULAR BIOLOGY OF THE CELL 712 1% 0% 14
10 CANCER BIOLOGY & THERAPY 533 1% 0% 7

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 PAK1 1273818 8% 54% 75 Search PAK1 Search PAK1
2 P21 ACTIVATED KINASE 1106741 7% 54% 66 Search P21+ACTIVATED+KINASE Search P21+ACTIVATED+KINASE
3 PAK4 964358 4% 86% 36 Search PAK4 Search PAK4
4 PAK 586172 5% 38% 49 Search PAK Search PAK
5 GIT1 423896 2% 59% 23 Search GIT1 Search GIT1
6 PAK5 315129 1% 92% 11 Search PAK5 Search PAK5
7 P21 ACTIVATED KINASE 1 292983 2% 63% 15 Search P21+ACTIVATED+KINASE+1 Search P21+ACTIVATED+KINASE+1
8 G PROTEIN COUPLED RECEPTOR KINASE INTERACTING PROTEIN 1 253145 1% 90% 9 Search G+PROTEIN+COUPLED+RECEPTOR+KINASE+INTERACTING+PROTEIN+1 Search G+PROTEIN+COUPLED+RECEPTOR+KINASE+INTERACTING+PROTEIN+1
9 P21 ACTIVATED KINASE 4 250021 1% 100% 8 Search P21+ACTIVATED+KINASE+4 Search P21+ACTIVATED+KINASE+4
10 PAK6 222240 1% 89% 8 Search PAK6 Search PAK6

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 KING, H , NICHOLAS, NS , WELLS, CM , (2014) ROLE OF P-21-ACTIVATED KINASES IN CANCER PROGRESSION.INTERNATIONAL REVIEW OF CELL AND MOLECULAR BIOLOGY, VOL 309. VOL. 309. ISSUE . P. 347 -387 178 85% 19
2 KUMAR, R , LI, DQ , (2016) PAKS IN HUMAN CANCER PROGRESSION: FROM INCEPTION TO CANCER THERAPEUTIC TO FUTURE ONCOBIOLOGY.ADVANCES IN CANCER RESEARCH, VOL 130. VOL. 130. ISSUE . P. 137 -209 184 62% 4
3 KUMAR, R , SANAWAR, R , LI, XD , LI, F , (2017) STRUCTURE, BIOCHEMISTRY, AND BIOLOGY OF PAK KINASES.GENE. VOL. 605. ISSUE . P. 20 -31 164 73% 0
4 RADU, M , SEMENOVA, G , KOSOFF, R , CHERNOFF, J , (2014) PAK SIGNALLING DURING THE DEVELOPMENT AND PROGRESSION OF CANCER.NATURE REVIEWS CANCER. VOL. 14. ISSUE 1. P. 13 -25 102 73% 72
5 SENAPEDIS, W , CROCHIERE, M , BALOGLU, E , LANDESMAN, Y , (2016) THERAPEUTIC POTENTIAL OF TARGETING PAK SIGNALING.ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY. VOL. 16. ISSUE 1. P. 75 -88 137 64% 3
6 WHALE, A , HASHIM, FN , FRAM, S , JONES, GE , WELLS, CM , (2011) SIGNALLING TO CANCER CELL INVASION THROUGH PAK FAMILY KINASES.FRONTIERS IN BIOSCIENCE-LANDMARK. VOL. 16. ISSUE . P. 849 -864 109 81% 47
7 BOKOCH, GM , (2003) BIOLOGY OF THE P21-ACTIVATED KINASES.ANNUAL REVIEW OF BIOCHEMISTRY. VOL. 72. ISSUE . P. 743-781 119 55% 676
8 DUMMLER, B , OHSHIRO, K , KUMAR, R , FIELD, J , (2009) PAK PROTEIN KINASES AND THEIR ROLE IN CANCER.CANCER AND METASTASIS REVIEWS. VOL. 28. ISSUE 1-2. P. 51 -63 106 68% 127
9 KICHINA, JV , GOC, A , AL-HUSEIN, B , SOMANATH, PR , KANDEL, ES , (2010) PAK1 AS A THERAPEUTIC TARGET.EXPERT OPINION ON THERAPEUTIC TARGETS. VOL. 14. ISSUE 7. P. 703 -725 136 59% 38
10 HA, BH , MORSE, EM , TURK, BE , BOGGON, TJ , (2015) SIGNALING, REGULATION, AND SPECIFICITY OF THE TYPE II P21-ACTIVATED KINASES.JOURNAL OF BIOLOGICAL CHEMISTRY. VOL. 290. ISSUE 21. P. 12975 -12983 77 81% 5

Classes with closest relation at Level 1


Rank Class id link
1 1558 RHO GTPASES//TIAM1//RHOB
2 28520 MAP4K4//TNIK//MST3
3 36779 CDK11P58//PITSLRE//CDK11
4 29090 MIG 6//ACK1//RALT
5 34692 PKN//PRK1//PKN ALPHA
6 22654 VAV//VAV1//VAV PROTO ONCOGENE
7 37377 RSF 1//HBXAP//BASIC SCI INT HLTH
8 10527 COFILIN//LIM KINASE//ADF COFILIN
9 36294 EBP1//ERBB3 BINDING PROTEIN 1//PA2G4
10 8584 ADP RIBOSYLATION FACTOR//ARF6//CYTOHESIN

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