Class information for:
Level 1: VAV//VAV1//VAV PROTO ONCOGENE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
22654 373 47.6 95%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
269 3       CELL BIOLOGY//CAVEOLIN 1//CAVEOLAE 44007
536 2             X LINKED AGAMMAGLOBULINEMIA//BTK//SH2 DOMAIN 14793
22654 1                   VAV//VAV1//VAV PROTO ONCOGENE 373

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 VAV authKW 2517403 17% 50% 62
2 VAV1 authKW 1637250 8% 67% 30
3 VAV PROTO ONCOGENE authKW 245590 1% 100% 3
4 VAV3 authKW 210499 2% 43% 6
5 VAV2 authKW 201499 2% 31% 8
6 GDP GTP EXCHANGE FACTORS authKW 184191 1% 75% 3
7 HUBERT H HUMPHREY EXPT MED CANC address 172915 3% 16% 13
8 APL DERIVED CELLS authKW 163727 1% 100% 2
9 SLP76 authKW 163727 1% 100% 2
10 VAV FAMILY authKW 163727 1% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Cell Biology 2717 44% 0% 163
2 Biochemistry & Molecular Biology 1100 46% 0% 171
3 Immunology 544 20% 0% 73
4 Oncology 513 21% 0% 77
5 Hematology 184 8% 0% 28
6 Medicine, Research & Experimental 120 8% 0% 29
7 Genetics & Heredity 113 9% 0% 32
8 Biophysics 28 4% 0% 16
9 Biochemical Research Methods 9 3% 0% 10
10 Cell & Tissue Engineering 9 1% 0% 2

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 HUBERT H HUMPHREY EXPT MED CANC 172915 3% 16% 13
2 INVEST CANC 111891 8% 5% 29
3 UNIT SINGLE MOL IMMUNOIMAGING 109150 1% 67% 2
4 MOL IMMUNOL PROGRAMME 106935 2% 15% 9
5 BIOL MOL CELULAR CANC 88229 6% 5% 21
6 ADV TECHNOL THER IES LTTA 81863 0% 100% 1
7 BIOIBER 81863 0% 100% 1
8 BIOL MOL CELULAR CANC IBSAL 81863 0% 100% 1
9 BIOL ULTRASTRUCT NOYAU 81863 0% 100% 1
10 BRIGHAM WOMENS HOSP MED EXPTL MED 81863 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ONCOGENE 2812 7% 0% 25
2 CRITICAL REVIEWS IN ONCOGENESIS 2496 1% 2% 2
3 CELLULAR SIGNALLING 1866 3% 0% 10
4 MOLECULAR AND CELLULAR BIOLOGY 1599 6% 0% 21
5 CELL GROWTH & DIFFERENTIATION 924 1% 0% 4
6 SCIENCE SIGNALING 841 1% 0% 4
7 JOURNAL OF EXPERIMENTAL MEDICINE 793 3% 0% 11
8 JOURNAL OF BIOLOGICAL CHEMISTRY 658 10% 0% 36
9 M S-MEDECINE SCIENCES 606 1% 0% 5
10 NATURE IMMUNOLOGY 587 1% 0% 4

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 VAV 2517403 17% 50% 62 Search VAV Search VAV
2 VAV1 1637250 8% 67% 30 Search VAV1 Search VAV1
3 VAV PROTO ONCOGENE 245590 1% 100% 3 Search VAV+PROTO+ONCOGENE Search VAV+PROTO+ONCOGENE
4 VAV3 210499 2% 43% 6 Search VAV3 Search VAV3
5 VAV2 201499 2% 31% 8 Search VAV2 Search VAV2
6 GDP GTP EXCHANGE FACTORS 184191 1% 75% 3 Search GDP+GTP+EXCHANGE+FACTORS Search GDP+GTP+EXCHANGE+FACTORS
7 APL DERIVED CELLS 163727 1% 100% 2 Search APL+DERIVED+CELLS Search APL+DERIVED+CELLS
8 SLP76 163727 1% 100% 2 Search SLP76 Search SLP76
9 VAV FAMILY 163727 1% 100% 2 Search VAV+FAMILY Search VAV+FAMILY
10 VAV3 ONCOGENE 163727 1% 100% 2 Search VAV3+ONCOGENE Search VAV3+ONCOGENE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 KATZAV, S , (2015) VAV1: A DR. JEKYLL AND MR. HYDE PROTEIN - GOOD FOR THE HEMATOPOIETIC SYSTEM, BAD FOR CANCER.ONCOTARGET. VOL. 6. ISSUE 30. P. 28731 -28742 72 67% 1
2 TYBULEWICZ, VL , (2005) VAV-FAMILY PROTEINS IN T-CELL SIGNALLING.CURRENT OPINION IN IMMUNOLOGY. VOL. 17. ISSUE 3. P. 267-274 48 72% 211
3 LAZER, G , KATZAV, S , (2011) GUANINE NUCLEOTIDE EXCHANGE FACTORS FOR RHOGTPASES: GOOD THERAPEUTIC TARGETS FOR CANCER THERAPY?.CELLULAR SIGNALLING. VOL. 23. ISSUE 6. P. 969 -979 64 38% 55
4 KATZAV, S , (2007) FLESH AND BLOOD: THE STORY OF VAV1, A GENE THAT SIGNALS IN HEMATOPOLETIC CELLS BUT CAN BE TRANSFORMING IN HUMAN MALIGNANCIES.CANCER LETTERS. VOL. 255. ISSUE 2. P. 241-254 63 49% 17
5 TURNER, M , BILLADEAU, DD , (2002) VAV PROTEINS AS SIGNAL INTEGRATORS FOR MULTI-SUBUNIT IMMUNE-RECOGNITION RECEPTORS.NATURE REVIEWS IMMUNOLOGY. VOL. 2. ISSUE 7. P. 476-486 55 51% 207
6 BUSTELO, XR , (2000) REGULATORY AND SIGNALING PROPERTIES OF THE VAV FAMILY.MOLECULAR AND CELLULAR BIOLOGY. VOL. 20. ISSUE 5. P. 1461-1477 60 36% 375
7 BARREIRA, M , FABBIANO, S , COUCEIRO, JR , TORREIRA, E , MARTINEZ-TORRECUADRADA, JL , MONTOYA, G , LLORCA, O , BUSTELO, XR , (2014) THE C-TERMINAL SH3 DOMAIN CONTRIBUTES TO THE INTRAMOLECULAR INHIBITION OF VAV FAMILY PROTEINS.SCIENCE SIGNALING. VOL. 7. ISSUE 321. P. - 37 59% 2
8 TYBULEWICZ, VLJ , ARDOUIN, L , PRISCO, A , REYNOLDS, LF , (2003) VAV1: A KEY SIGNAL TRANSDUCER DOWNSTREAM OF THE TCR.IMMUNOLOGICAL REVIEWS. VOL. 192. ISSUE 1. P. 42-52 48 54% 75
9 YIN, J , WAN, YJ , LI, SY , DU, MJ , ZHANG, CZ , ZHOU, XL , CAO, YJ , (2011) THE DISTINCT ROLE OF GUANINE NUCLEOTIDE EXCHANGE FACTOR VAV1 IN BCL-2 TRANSCRIPTION AND APOPTOSIS INHIBITION IN JURKAT LEUKEMIA T CELLS.ACTA PHARMACOLOGICA SINICA. VOL. 32. ISSUE 1. P. 99-107 30 71% 3
10 RAZANADRAKOTO, L , CORMIER, F , LAURIENTE, V , DONDI, E , GARDANO, L , KATZAV, S , GUITTAT, L , VARIN-BLANK, N , (2015) MUTATION OF VAV1 ADAPTOR REGION REVEALS A NEW ONCOGENIC ACTIVATION.ONCOTARGET. VOL. 6. ISSUE 4. P. 2524 -2538 32 58% 2

Classes with closest relation at Level 1


Rank Class id link
1 13788 SLP 76//ADAP//SECT LYMPHOCYTE SIGNALING
2 1558 RHO GTPASES//TIAM1//RHOB
3 36304 SWAP 70//SWITCH ASSOCIATED PROTEIN 70//DEF6
4 4230 IMMUNOLOGICAL SYNAPSE//LYMPHOCYTE INTERACT//PROGRAM MOL PATHOGENESIS
5 14390 CBL//CBL B//C CBL
6 18972 SYK//SPLEEN TYROSINE KINASE//FOSTAMATINIB
7 12290 SH3 DOMAIN//SH2 DOMAIN//GRB2
8 15482 BCL10//PKC THETA//CARMA3
9 30657 KBG SYNDROME//AARSKOG SCOTT SYNDROME//FGD1
10 4882 P56LCK//LCK//LCK INHIBITOR

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