Class information for:
Level 1: RHO GTPASES//TIAM1//RHOB

Basic class information

Class id #P Avg. number of
references
Database coverage
of references
1558 2595 47.6 94%



Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes

The table includes all classes above and classes immediately below the current class.



Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
269 3       CELL BIOLOGY//CAVEOLIN 1//CAVEOLAE 44007
536 2             X LINKED AGAMMAGLOBULINEMIA//BTK//SH2 DOMAIN 14793
1558 1                   RHO GTPASES//TIAM1//RHOB 2595

Terms with highest relevance score



rank Term termType Chi square Shr. of publ. in
class containing
term
Class's shr. of
term's tot. occurrences
#P with
term in
class
1 RHO GTPASES authKW 507663 8% 21% 208
2 TIAM1 authKW 338037 2% 57% 50
3 RHOB authKW 309563 2% 53% 50
4 RAC1 authKW 262871 5% 16% 141
5 RHOC authKW 239245 1% 54% 38
6 RHO authKW 228789 6% 13% 145
7 RAC authKW 202376 4% 16% 107
8 RHOE authKW 189800 1% 73% 22
9 RHOGDI2 authKW 178900 1% 72% 21
10 RHOA authKW 178126 5% 11% 136

Web of Science journal categories



Rank Term Chi square Shr. of publ. in
class containing
term
Class's shr. of
term's tot. occurrences
#P with term
in class
1 Cell Biology 14141 38% 0% 989
2 Biochemistry & Molecular Biology 8075 47% 0% 1218
3 Oncology 4250 22% 0% 579
4 Genetics & Heredity 596 8% 0% 199
5 Biophysics 423 6% 0% 148
6 Developmental Biology 271 2% 0% 63
7 Biochemical Research Methods 149 4% 0% 91
8 Hematology 113 3% 0% 74
9 Medicine, Research & Experimental 77 3% 0% 85
10 Neurosciences 56 6% 0% 143

Address terms



Rank Term Chi square Shr. of publ. in
class containing
term
Class's shr. of
term's tot. occurrences
#P with
term in
class
1 SIGNALING BIOMOL SYST 47061 0% 100% 4
2 CHILDRENS HOSP FDN 34897 1% 13% 22
3 ONCOGENE SIGNAL TRANSDUCT GRP 32727 0% 35% 8
4 CELL ADHES UNIT 28865 0% 27% 9
5 HOWARD HUGHES MED SECT PEDIAT HEMATOL ONCOL 23530 0% 100% 2
6 LIFE SCI LIFE ENVIRONM SCI 23530 0% 100% 2
7 EXPT HEMATOL CANC BIOL 21645 1% 7% 25
8 UMR CRCT 1037 21175 0% 60% 3
9 EXPT HEMATOL 20148 2% 3% 53
10 CANC UK PATERSON CANC 19602 0% 33% 5

Journals



Rank Term Chi square Shr. of publ. in
class containing
term
Class's shr. of
term's tot. occurrences
#P with
term in
class
1 JOURNAL OF BIOLOGICAL CHEMISTRY 8410 13% 0% 335
2 ONCOGENE 7047 4% 1% 105
3 CELLULAR SIGNALLING 3840 1% 1% 38
4 MOLECULAR AND CELLULAR BIOLOGY 3099 3% 0% 78
5 MOLECULAR BIOLOGY OF THE CELL 2917 2% 1% 46
6 JOURNAL OF CELL SCIENCE 1916 2% 0% 47
7 METHODS IN ENZYMOLOGY 1866 2% 0% 52
8 TRENDS IN CELL BIOLOGY 1289 1% 1% 14
9 CELL ADHESION & MIGRATION 967 0% 1% 7
10 EXPERIMENTAL CELL RESEARCH 892 1% 0% 32

Author Key Words



Rank Term Chi square Shr. of publ. in
class containing
term
Class's shr. of
term's tot. occurrences
#P with
term in
class
LCSH search Wikipedia search
1 RHO GTPASES 507663 8% 21% 208 Search RHO+GTPASES Search RHO+GTPASES
2 TIAM1 338037 2% 57% 50 Search TIAM1 Search TIAM1
3 RHOB 309563 2% 53% 50 Search RHOB Search RHOB
4 RAC1 262871 5% 16% 141 Search RAC1 Search RAC1
5 RHOC 239245 1% 54% 38 Search RHOC Search RHOC
6 RHO 228789 6% 13% 145 Search RHO Search RHO
7 RAC 202376 4% 16% 107 Search RAC Search RAC
8 RHOE 189800 1% 73% 22 Search RHOE Search RHOE
9 RHOGDI2 178900 1% 72% 21 Search RHOGDI2 Search RHOGDI2
10 RHOA 178126 5% 11% 136 Search RHOA Search RHOA

Core articles

The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.



Rank Reference # ref. in
cl.
Shr. of ref. in
cl.
Citations
1 HEASMAN, SJ , RIDLEY, AJ , (2008) MAMMALIAN RHO GTPASES: NEW INSIGHTS INTO THEIR FUNCTIONS FROM IN VIVO STUDIES.NATURE REVIEWS MOLECULAR CELL BIOLOGY. VOL. 9. ISSUE 9. P. 690 -701 86 60% 841
2 AITTALEB, M , BOGUTH, CA , TESMER, JJG , (2010) STRUCTURE AND FUNCTION OF HETEROTRIMERIC G PROTEIN-REGULATED RHO GUANINE NUCLEOTIDE EXCHANGE FACTORS.MOLECULAR PHARMACOLOGY. VOL. 77. ISSUE 2. P. 111-125 100 72% 60
3 ELLENBROEK, SIJ , COLLARD, JG , (2007) RHO GTPASES: FUNCTIONS AND ASSOCIATION WITH CANCER.CLINICAL & EXPERIMENTAL METASTASIS. VOL. 24. ISSUE 8. P. 657 -672 97 63% 138
4 GARCIA-MATA, R , BOULTER, E , BURRIDGE, K , (2011) THE 'INVISIBLE HAND': REGULATION OF RHO GTPASES BY RHOGDIS.NATURE REVIEWS MOLECULAR CELL BIOLOGY. VOL. 12. ISSUE 8. P. 493 -504 67 66% 159
5 KARLSSON, R , PEDERSEN, ED , WANG, Z , BRAKEBUSCH, C , (2009) RHO GTPASE FUNCTION IN TUMORIGENESIS.BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER. VOL. 1796. ISSUE 2. P. 91 -98 70 69% 171
6 VEGA, FM , RIDLEY, AJ , (2008) RHO GTPASES IN CANCER CELL BIOLOGY.FEBS LETTERS. VOL. 582. ISSUE 14. P. 2093-2101 55 69% 330
7 WERTHEIMER, E , GUTIERREZ-UZQUIZA, A , ROSEMBLIT, C , LOPEZ-HABER, C , SOSA, MS , KAZANIETZ, MG , (2012) RAC SIGNALING IN BREAST CANCER: A TALE OF GEFS AND GAPS.CELLULAR SIGNALLING. VOL. 24. ISSUE 2. P. 353 -362 79 54% 65
8 SUN, D , XU, D , ZHANG, BL , (2006) RAC SIGNALING IN TUMORIGENESIS AND AS TARGET FOR ANTICANCER DRUG DEVELOPMENT.DRUG RESISTANCE UPDATES. VOL. 9. ISSUE 6. P. 274-287 96 61% 33
9 GONZALEZ-BILLAULT, C , MUNOZ-LLANCAO, P , HENRIQUEZ, DR , WOJNACKI, J , CONDE, C , CACERES, A , (2012) THE ROLE OF SMALL GTPASES IN NEURONAL MORPHOGENESIS AND POLARITY.CYTOSKELETON. VOL. 69. ISSUE 7. P. 464-485 106 43% 27
10 JAISWAL, M , GREMER, L , DVORSKY, R , HAEUSLER, LC , CIRSTEA, IC , UHLENBROCK, K , AHMADIAN, MR , (2011) MECHANISTIC INSIGHTS INTO SPECIFICITY, ACTIVITY, AND REGULATORY ELEMENTS OF THE REGULATOR OF G-PROTEIN SIGNALING (RGS)-CONTAINING RHO-SPECIFIC GUANINE NUCLEOTIDE EXCHANGE FACTORS (GEFS) P115, PDZ-RHOGEF (PRG), AND LEUKEMIA-ASSOCIATED RHOGEF (LARG).JOURNAL OF BIOLOGICAL CHEMISTRY. VOL. 286. ISSUE 20. P. 18202-18212 61 76% 24

Classes with closest relation at Level 1



Rank Class id link
1 22654 VAV//VAV1//VAV PROTO ONCOGENE
2 34692 PKN//PRK1//PKN ALPHA
3 11502 PAK1//P21 ACTIVATED KINASE//PAK4
4 26062 LOE 908//G ALPHA12//VOLTAGE INDEPENDENT CALCIUM CHANNEL
5 7347 FASUDIL//RHO KINASE//Y 27632
6 30657 KBG SYNDROME//AARSKOG SCOTT SYNDROME//FGD1
7 36304 SWAP 70//SWITCH ASSOCIATED PROTEIN 70//DEF6
8 25652 IQGAP1//IQGAP2//IQGAP
9 23000 DLC1//DELETED IN LIVER CANCER 1//DLC 1
10 4031 RAS//RAS PROTEINS//ONCOGENIC RAS P21

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