Class information for:
Level 1: PEUTZ JEGHERS SYNDROME//LKB1//JUVENILE POLYPOSIS

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
9462 1153 34.0 77%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
262 3       AUTOPHAGY//RESVERATROL//HISTONE DEACETYLASE INHIBITOR 44558
2357 2             PEUTZ JEGHERS SYNDROME//AMPK//LKB1 4361
9462 1                   PEUTZ JEGHERS SYNDROME//LKB1//JUVENILE POLYPOSIS 1153

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PEUTZ JEGHERS SYNDROME authKW 4531695 21% 72% 238
2 LKB1 authKW 1390483 11% 41% 128
3 JUVENILE POLYPOSIS authKW 1040325 5% 71% 55
4 STK11 authKW 780958 4% 72% 41
5 JUVENILE POLYPOSIS SYNDROME authKW 576702 2% 78% 28
6 JUVENILE POLYP authKW 494989 2% 69% 27
7 PEUTZ JEGHERS authKW 476660 2% 75% 24
8 HAMARTOMATOUS POLYPS authKW 286271 2% 54% 20
9 STK11 GENE authKW 267023 1% 92% 11
10 LKB1 STK11 authKW 220678 1% 83% 10

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Gastroenterology & Hepatology 6244 23% 0% 261
2 Oncology 2157 24% 0% 273
3 Genetics & Heredity 1163 14% 0% 165
4 Surgery 872 16% 0% 190
5 Pediatrics 838 10% 0% 117
6 Pathology 749 8% 0% 90
7 Cell Biology 415 12% 0% 133
8 Medicine, General & Internal 111 6% 0% 72
9 Biochemistry & Molecular Biology 65 11% 0% 128
10 Developmental Biology 34 1% 0% 17

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 TUMOUR GENET GRP 162199 1% 88% 7
2 POLYPOSIS REGISTRY 116752 2% 21% 21
3 GENET MED DIMIMP 52964 0% 100% 2
4 ANIM MODELS CANC 47665 0% 60% 3
5 MOL POPULAT GENET 40795 2% 7% 21
6 PROGRAMA EPIGENET BIOL CANC PEBC 35308 0% 67% 2
7 UNITE GASTROENTEROL HEPATOL 35308 0% 67% 2
8 BIOCHEM GENOME SCALE BIOL PROGRAM 26482 0% 100% 1
9 BIOL CELLULAIRE QUANTIT 26482 0% 100% 1
10 BREAST CHECK ECCLES UNIT 26482 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 FAMILIAL CANCER 7725 1% 2% 16
2 JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION 1774 2% 0% 22
3 DISEASES OF THE COLON & RECTUM 1470 2% 0% 21
4 AMERICAN JOURNAL OF GASTROENTEROLOGY 1405 2% 0% 25
5 CLINICAL GENETICS 996 1% 0% 14
6 BMC MEDICAL GENETICS 884 1% 0% 7
7 ENDOSCOPY 865 1% 0% 13
8 NOUVELLE REVUE DE MEDECINE DE TOULOUSE 801 0% 3% 1
9 JOURNAL OF MEDICAL GENETICS 751 1% 0% 13
10 ONCOGENE 674 2% 0% 22

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 PEUTZ JEGHERS SYNDROME 4531695 21% 72% 238 Search PEUTZ+JEGHERS+SYNDROME Search PEUTZ+JEGHERS+SYNDROME
2 LKB1 1390483 11% 41% 128 Search LKB1 Search LKB1
3 JUVENILE POLYPOSIS 1040325 5% 71% 55 Search JUVENILE+POLYPOSIS Search JUVENILE+POLYPOSIS
4 STK11 780958 4% 72% 41 Search STK11 Search STK11
5 JUVENILE POLYPOSIS SYNDROME 576702 2% 78% 28 Search JUVENILE+POLYPOSIS+SYNDROME Search JUVENILE+POLYPOSIS+SYNDROME
6 JUVENILE POLYP 494989 2% 69% 27 Search JUVENILE+POLYP Search JUVENILE+POLYP
7 PEUTZ JEGHERS 476660 2% 75% 24 Search PEUTZ+JEGHERS Search PEUTZ+JEGHERS
8 HAMARTOMATOUS POLYPS 286271 2% 54% 20 Search HAMARTOMATOUS+POLYPS Search HAMARTOMATOUS+POLYPS
9 STK11 GENE 267023 1% 92% 11 Search STK11+GENE Search STK11+GENE
10 LKB1 STK11 220678 1% 83% 10 Search LKB1+STK11 Search LKB1+STK11

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 HEZEL, AF , BARDEESY, N , (2008) LKB1; LINKING CELL STRUCTURE AND TUMOR SUPPRESSION.ONCOGENE. VOL. 27. ISSUE 55. P. 6908 -6919 82 67% 108
2 LAUNONEN, V , (2005) MUTATIONS IN THE HUMAN LKB1/STK11 GENE.HUMAN MUTATION. VOL. 26. ISSUE 4. P. 291-297 65 96% 48
3 GAN, RY , LI, HB , (2014) RECENT PROGRESS ON LIVER KINASE B1 (LKB1): EXPRESSION, REGULATION, DOWNSTREAM SIGNALING AND CANCER SUPPRESSIVE FUNCTION.INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. VOL. 15. ISSUE 9. P. 16698 -16718 74 62% 17
4 BEGGS, AD , LATCHFORD, AR , VASEN, HFA , MOSLEIN, G , ALONSO, A , ARETZ, S , BERTARIO, L , BLANCO, I , BULOW, S , BURN, J , ET AL (2010) PEUTZ-JEGHERS SYNDROME: A SYSTEMATIC REVIEW AND RECOMMENDATIONS FOR MANAGEMENT.GUT. VOL. 59. ISSUE 7. P. 975 -986 58 68% 130
5 MCGARRITY, TJ , AMOS, C , (2006) PEUTZ-JEGHERS SYNDROME: CLINICOPATHOLOGY AND MOLECULAR ALTERATIONS.CELLULAR AND MOLECULAR LIFE SCIENCES. VOL. 63. ISSUE 18. P. 2135-2144 68 79% 54
6 SHORNING, BY , CLARKE, AR , (2011) LKB1 LOSS OF FUNCTION STUDIED IN VIVO.FEBS LETTERS. VOL. 585. ISSUE 7. P. 958 -966 77 61% 7
7 VAN LIER, MGF , WAGNER, A , MATHUS-VLIEGEN, EMH , KUIPERS, EJ , STEYERBERG, EW , VAN LEERDAM, ME , (2010) HIGH CANCER RISK IN PEUTZ-JEGHERS SYNDROME: A SYSTEMATIC REVIEW AND SURVEILLANCE RECOMMENDATIONS.AMERICAN JOURNAL OF GASTROENTEROLOGY. VOL. 105. ISSUE 6. P. 1258 -1264 43 84% 118
8 HERRMANN, JL , BYEKOVA, Y , ELMETS, CA , ATHAR, M , (2011) LIVER KINASE B1 (LKB1) IN THE PATHOGENESIS OF EPITHELIAL CANCERS.CANCER LETTERS. VOL. 306. ISSUE 1. P. 1 -9 65 65% 22
9 SANCHEZ-CESPEDES, M , (2007) A ROLE FOR LKB1 GENE IN HUMAN CANCER BEYOND THE PEUTZ-JEGHERS SYNDROME.ONCOGENE. VOL. 26. ISSUE 57. P. 7825-7832 47 85% 110
10 JELSIG, AM , (2016) HAMARTOMATOUS POLYPS - A CLINICAL AND MOLECULAR GENETIC STUDY.DANISH MEDICAL JOURNAL. VOL. 63. ISSUE 8. P. - 78 50% 0

Classes with closest relation at Level 1


Rank Class id link
1 33823 CRONKHITE CANADA SYNDROME//ACQUIRED GASTROINTESTINAL POLYPOSIS SYNDROME//ANTI HELICOBACTER PYLORI REGIMEN
2 28466 CELL SIGNALING METAB//SALT INDUCIBLE KINASE//SALT INDUCIBLE KINASE 1
3 5374 FAMILIAL ADENOMATOUS POLYPOSIS//APC GENE//MUTYH
4 23435 TOPK//PBK TOPK//MELK
5 1917 AMPK//AMP ACTIVATED PROTEIN KINASE//AICAR
6 34277 FILIFORM POLYPOSIS//PSEUDOPOLYPS//GIANT PSEUDOPOLYP
7 2908 PTEN//COWDEN SYNDROME//LHERMITTE DUCLOS DISEASE
8 23203 HEREDITARY DIFFUSE GASTRIC CANCER//PROPHYLACTIC GASTRECTOMY//HDGC
9 3506 CAPSULE ENDOSCOPY//OBSCURE GASTROINTESTINAL BLEEDING//DOUBLE BALLOON ENTEROSCOPY
10 11474 FUNDIC GLAND POLYP//GASTRIC POLYPS//GASTRIC HYPERPLASTIC POLYP

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