Class information for:
Level 1: CALCINEURIN//RCAN1//DSCR1

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
12551 897 43.2 87%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
584 3       POMPE DISEASE//PIN1//CYCLOPHILIN 15652
2159 2             PIN1//CYCLOPHILIN//CALCINEURIN 4989
12551 1                   CALCINEURIN//RCAN1//DSCR1 897

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CALCINEURIN authKW 1851261 32% 19% 290
2 RCAN1 authKW 1025943 4% 84% 36
3 DSCR1 authKW 580867 3% 74% 23
4 ADAPT78 authKW 377058 1% 92% 12
5 CALCINEURIN SUBUNIT B authKW 204241 1% 100% 6
6 TAX 6 authKW 204241 1% 100% 6
7 GENE ENGN BIOTECHNOL BEIJING address 181534 1% 44% 12
8 BEIJING address 175995 5% 13% 41
9 CALCIPRESSIN authKW 175062 1% 86% 6
10 CALCINEURIN B SUBUNIT authKW 170201 1% 100% 5

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Biochemistry & Molecular Biology 4251 57% 0% 508
2 Biophysics 1058 13% 0% 119
3 Cell Biology 878 18% 0% 157
4 Neurosciences 735 19% 0% 167
5 Genetics & Heredity 61 5% 0% 44
6 Biology 25 2% 0% 20
7 Immunology 24 4% 0% 40
8 Biochemical Research Methods 23 3% 0% 24
9 Pharmacology & Pharmacy 12 5% 0% 45
10 Developmental Biology 12 1% 0% 10

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 GENE ENGN BIOTECHNOL BEIJING 181534 1% 44% 12
2 BEIJING 175995 5% 13% 41
3 PROV MINIST ESTABLISHED OURCE COMP 68080 0% 100% 2
4 ETHEL PERCY ANDRUS GERONTOL 48700 2% 7% 21
5 CELL DEATH DIS MRC 45386 0% 67% 2
6 LOUISIANA STATE HLTH SCI 45386 0% 67% 2
7 MOL CELLULAR NEUROSCI GRP 45386 0% 67% 2
8 UNIT BIOSIGNAL 45386 0% 67% 2
9 CHONGQING CITY TRANSLAT MED COGNIT DE 38897 0% 29% 4
10 12501 WASHINGTON AVE 34040 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 IUBMB LIFE 2650 1% 1% 12
2 JOURNAL OF BIOLOGICAL CHEMISTRY 1758 10% 0% 91
3 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 1296 6% 0% 52
4 ADVANCES IN SECOND MESSENGER AND PHOSPHOPROTEIN RESEARCH 1287 0% 1% 3
5 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 1214 3% 0% 25
6 MOLECULES AND CELLS 576 1% 0% 7
7 SECOND MESSENGERS AND PHOSPHOPROTEINS 565 0% 2% 1
8 JOURNAL OF NEUROCHEMISTRY 559 2% 0% 19
9 BIOCHEMISTRY 528 3% 0% 30
10 GENES & GENOMICS 388 0% 0% 3

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 CALCINEURIN 1851261 32% 19% 290 Search CALCINEURIN Search CALCINEURIN
2 RCAN1 1025943 4% 84% 36 Search RCAN1 Search RCAN1
3 DSCR1 580867 3% 74% 23 Search DSCR1 Search DSCR1
4 ADAPT78 377058 1% 92% 12 Search ADAPT78 Search ADAPT78
5 CALCINEURIN SUBUNIT B 204241 1% 100% 6 Search CALCINEURIN+SUBUNIT+B Search CALCINEURIN+SUBUNIT+B
6 TAX 6 204241 1% 100% 6 Search TAX+6 Search TAX+6
7 CALCIPRESSIN 175062 1% 86% 6 Search CALCIPRESSIN Search CALCIPRESSIN
8 CALCINEURIN B SUBUNIT 170201 1% 100% 5 Search CALCINEURIN+B+SUBUNIT Search CALCINEURIN+B+SUBUNIT
9 RCAN 151628 1% 64% 7 Search RCAN Search RCAN
10 HAMSTER FIBROBLASTS 121569 1% 71% 5 Search HAMSTER+FIBROBLASTS Search HAMSTER+FIBROBLASTS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 MUSSON, REA , SMIT, NPM , (2011) REGULATORY MECHANISMS OF CALCINEURIN PHOSPHATASE ACTIVITY.CURRENT MEDICINAL CHEMISTRY. VOL. 18. ISSUE 2. P. 301-315 118 56% 15
2 PORTA, S , MARTI, E , DE LA LUNA, S , ARBONES, ML , (2007) DIFFERENTIAL EXPRESSION OF MEMBERS OF THE RCAN FAMILY OF CALCINEURIN REGULATORS SUGGESTS SELECTIVE FUNCTIONS FOR THESE PROTEINS IN THE BRAIN.EUROPEAN JOURNAL OF NEUROSCIENCE. VOL. 26. ISSUE 5. P. 1213 -1226 63 88% 19
3 RUSNAK, F , MERTZ, P , (2000) CALCINEURIN: FORM AND FUNCTION.PHYSIOLOGICAL REVIEWS. VOL. 80. ISSUE 4. P. 1483 -1521 128 30% 732
4 WU, YL , LY, PTT , SONG, WH , (2014) ABERRANT EXPRESSION OF RCAN1 IN ALZHEIMER'S PATHOGENESIS: A NEW MOLECULAR MECHANISM AND A NOVEL DRUG TARGET.MOLECULAR NEUROBIOLOGY. VOL. 50. ISSUE 3. P. 1085 -1097 81 54% 4
5 TU, LH , LIU, HP , LUO, J , (2010) A NEW FAMILY OF REGULATORS OF CALCINEURIN (RCANS).PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS. VOL. 37. ISSUE 1. P. 22-28 52 84% 4
6 DAVIES, KJA , ERMAK, G , ROTHERMEL, BA , PRITCHARD, M , HEITMAN, J , AHNN, J , HENRIQUE-SILVA, F , CRAWFORD, D , CANAIDER, S , STRIPPOLI, P , ET AL (2007) RENAMING THE DSCR1/ADAPT78 GENE FAMILY AS RCAN: REGULATORS OF CALCINEURIN.FASEB JOURNAL. VOL. 21. ISSUE 12. P. 3023 -3028 43 88% 63
7 WU, YL , SONG, WH , (2013) REGULATION OF RCAN1 TRANSLATION AND ITS ROLE IN OXIDATIVE STRESS-INDUCED APOPTOSIS.FASEB JOURNAL. VOL. 27. ISSUE 1. P. 208-221 40 66% 16
8 LI, SJ , WANG, J , MA, L , LU, C , WANG, J , WU, JW , WANG, ZX , (2016) COOPERATIVE AUTOINHIBITION AND MULTI-LEVEL ACTIVATION MECHANISMS OF CALCINEURIN.CELL RESEARCH. VOL. 26. ISSUE 3. P. 336 -349 30 71% 1
9 KIM, SS , OH, Y , CHUNG, KC , SEO, SR , (2012) PROTEIN KINASE A PHOSPHORYLATES DOWN SYNDROME CRITICAL REGION 1 (RCAN1).BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. VOL. 418. ISSUE 4. P. 657-661 31 78% 5
10 MA, YP , JIANG, GH , WANG, QR , SUN, Y , ZHAO, YN , TONG, L , LUO, J , (2015) ENZYMATIC AND THERMODYNAMIC ANALYSIS OF CALCINEURIN INHIBITION BY RCAN1.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES. VOL. 72. ISSUE . P. 254 -260 26 81% 1

Classes with closest relation at Level 1


Rank Class id link
1 10893 NFAT//NUCLEAR FACTOR OF ACTIVATED T CELLS//CALCINEURIN
2 28246 MYHCI//UNIT PERIOPERAT PHYSIOL//CALCINEURIN
3 22835 FK506//GPI 1046//IMMUNOPHILIN
4 13375 MEMBRANE TRANSPORT//TRK1//ENA1
5 2873 CYCLOPHILIN//PEPTIDYL PROLYL CIS TRANS ISOMERASE//IMMUNOPHILIN
6 4501 PROTEIN PHOSPHATASE 1//INHIBITOR 2//GLYCOGEN SYNTHASE
7 24138 DARPP 32//PPP1R1B//T DARPP
8 8526 CARDIAC HYPERTROPHY//HYPERTROPHY//CARDIAC MED SECT
9 22211 IMMUKNOW//IMMUNE MONITORING//PHARMACODYNAMIC MONITORING
10 1576 CALMODULIN//DIPHENYLALKYLAMINES//PHOSPHOCALMODULIN

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