Class information for:
Level 2: PIN1//CYCLOPHILIN//CALCINEURIN

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
2159 4989 44.9 89%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
584 3       POMPE DISEASE//PIN1//CYCLOPHILIN 15652
2159 2             PIN1//CYCLOPHILIN//CALCINEURIN 4989
2873 1                   CYCLOPHILIN//PEPTIDYL PROLYL CIS TRANS ISOMERASE//IMMUNOPHILIN 2125
10893 1                   NFAT//NUCLEAR FACTOR OF ACTIVATED T CELLS//CALCINEURIN 1027
12551 1                   CALCINEURIN//RCAN1//DSCR1 897
17967 1                   PIN1//PPIASE//PARVULIN 573
22835 1                   FK506//GPI 1046//IMMUNOPHILIN 367

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PIN1 authKW 859907 4% 65% 217
2 CYCLOPHILIN authKW 832343 5% 55% 248
3 CALCINEURIN authKW 720989 9% 28% 427
4 IMMUNOPHILIN authKW 701986 4% 61% 188
5 PEPTIDYL PROLYL CIS TRANS ISOMERASE authKW 606883 3% 76% 131
6 PPIASE authKW 446770 2% 78% 94
7 FKBP authKW 410767 2% 65% 103
8 FK506 authKW 359323 5% 23% 259
9 PEPTIDYL PROLYL ISOMERASE authKW 281559 1% 72% 64
10 FK506 BINDING PROTEIN authKW 271661 1% 61% 73

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Biochemistry & Molecular Biology 13964 45% 0% 2235
2 Cell Biology 4815 17% 0% 868
3 Immunology 2436 12% 0% 609
4 Biophysics 2389 9% 0% 444
5 Neurosciences 676 9% 0% 466
6 Chemistry, Medicinal 539 4% 0% 192
7 Chemistry, Organic 244 5% 0% 244
8 Transplantation 200 2% 0% 86
9 Genetics & Heredity 184 4% 0% 201
10 Pharmacology & Pharmacy 146 6% 0% 298

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BEIJING 33137 1% 13% 42
2 GENE ENGN BIOTECHNOL BEIJING 32619 0% 44% 12
3 STRUCT MED BIOCHEM 23026 0% 47% 8
4 MEDCANC BIOL PROGRAM 21408 0% 50% 7
5 MED HEMATOL ONCOLCANC BIOL PROGRAM 20639 0% 38% 9
6 PROGRAM CELLULAR BIOL 15771 0% 37% 7
7 FATC MASS SPE OMETRY 13765 0% 75% 3
8 MOL CARDIOVASC BIOL PROGRAM 13765 0% 75% 3
9 UNIDAD NEUROINFLAMAC 13765 0% 75% 3
10 ADV TECHNOL PLATFORM S 12237 0% 100% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF BIOLOGICAL CHEMISTRY 4638 7% 0% 356
2 MOLECULAR AND CELLULAR BIOLOGY 2029 2% 0% 89
3 BIOCHEMISTRY 1844 3% 0% 134
4 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 1803 3% 0% 150
5 JOURNAL OF IMMUNOLOGY 1274 2% 0% 113
6 FEBS LETTERS 1173 2% 0% 94
7 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 1024 3% 0% 139
8 JOURNAL OF MOLECULAR BIOLOGY 901 1% 0% 62
9 BIOMOLECULAR NMR ASSIGNMENTS 857 0% 1% 10
10 IMMUNITY 823 0% 1% 22

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 PIN1 859907 4% 65% 217 Search PIN1 Search PIN1
2 CYCLOPHILIN 832343 5% 55% 248 Search CYCLOPHILIN Search CYCLOPHILIN
3 CALCINEURIN 720989 9% 28% 427 Search CALCINEURIN Search CALCINEURIN
4 IMMUNOPHILIN 701986 4% 61% 188 Search IMMUNOPHILIN Search IMMUNOPHILIN
5 PEPTIDYL PROLYL CIS TRANS ISOMERASE 606883 3% 76% 131 Search PEPTIDYL+PROLYL+CIS+TRANS+ISOMERASE Search PEPTIDYL+PROLYL+CIS+TRANS+ISOMERASE
6 PPIASE 446770 2% 78% 94 Search PPIASE Search PPIASE
7 FKBP 410767 2% 65% 103 Search FKBP Search FKBP
8 FK506 359323 5% 23% 259 Search FK506 Search FK506
9 PEPTIDYL PROLYL ISOMERASE 281559 1% 72% 64 Search PEPTIDYL+PROLYL+ISOMERASE Search PEPTIDYL+PROLYL+ISOMERASE
10 FK506 BINDING PROTEIN 271661 1% 61% 73 Search FK506+BINDING+PROTEIN Search FK506+BINDING+PROTEIN

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 KAY, JE , (1996) STRUCTURE-FUNCTION RELATIONSHIPS IN THE FK506-BINDING PROTEIN (FKBP) FAMILY OF PEPTIDYLPROLYL CIS-TRANS ISOMERASES.BIOCHEMICAL JOURNAL. VOL. 314. ISSUE . P. 361-385 239 81% 167
2 GALAT, A , METCALFE, SM , (1995) PEPTIDYLPROLINE CIS/TRANS ISOMERASES.PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY. VOL. 63. ISSUE 1. P. 67-118 240 71% 195
3 MUSSON, REA , SMIT, NPM , (2011) REGULATORY MECHANISMS OF CALCINEURIN PHOSPHATASE ACTIVITY.CURRENT MEDICINAL CHEMISTRY. VOL. 18. ISSUE 2. P. 301-315 159 76% 15
4 FISCHER, G , (1994) PEPTIDYL-PROLYL CIS/TRANS ISOMERASES AND THEIR EFFECTORS.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. VOL. 33. ISSUE 14. P. 1415-1436 210 76% 240
5 FANGHANEL, J , FISCHER, G , (2004) INSIGHTS INTO THE CATALYTIC MECHANISM OF PEPTIDYL PROLYL CIS/TRANS ISOMERASES.FRONTIERS IN BIOSCIENCE-LANDMARK. VOL. 9. ISSUE . P. 3453-3478 147 85% 136
6 ZHOU, XZ , LU, KP , (2016) THE ISOMERASE PIN1 CONTROLS NUMEROUS CANCER-DRIVING PATHWAYS AND IS A UNIQUE DRUG TARGET.NATURE REVIEWS CANCER. VOL. 16. ISSUE 7. P. 463 -478 124 64% 5
7 JACKSON, SE , (2013) PEPTIDE BOND CIS/TRANS ISOMERASES: A BIOCATALYSIS PERSPECTIVE OF CONFORMATIONAL DYNAMICS IN PROTEINS.MOLECULAR CHAPERONES. VOL. 328. ISSUE . P. 35-67 146 65% 0
8 HANES, SD , (2015) PROLYL ISOMERASES IN GENE TRANSCRIPTION.BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS. VOL. 1850. ISSUE 10. P. 2017 -2034 131 60% 6
9 GALAT, A , (2003) PEPTIDYLPROLYL CIS/TRANS ISOMERASES (IMMUNOPHILINS): BIOLOGICAL DIVERSITY TARGETS - FUNCTIONS.CURRENT TOPICS IN MEDICINAL CHEMISTRY. VOL. 3. ISSUE 12. P. 1315 -1347 128 68% 206
10 HAMILTON, GS , STEINER, JP , (1998) IMMUNOPHILINS: BEYOND IMMUNOSUPPRESSION.JOURNAL OF MEDICINAL CHEMISTRY. VOL. 41. ISSUE 26. P. 5119 -5143 153 72% 126

Classes with closest relation at Level 2


Rank Class id link
1 2619 CARNOSINE//CD147//EMMPRIN
2 1321 INTERLEUKIN 12//CD23//INTERLEUKIN 4
3 2158 NF KAPPA B//I KAPPA B//IKK
4 2731 DOWN SYNDROME//DYRK1A//TS65DN
5 93 TRANSPLANTATION//TRANSPLANTATION PROCEEDINGS//KIDNEY TRANSPLANTATION
6 1764 STIM1//ORAI1//STORE OPERATED CALCIUM ENTRY
7 1750 S100A4//S100A9//S100A8
8 3713 A20//LAPTM4B//WWP1
9 1709 C FOS//EGR 1//IMMEDIATE EARLY GENE
10 1220 PTEN//MTOR//COWDEN SYNDROME

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