Class information for:
Level 2: DOWN SYNDROME//DYRK1A//TS65DN

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
2731 3262 42.7 71%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
196 3       GENETICS & HEREDITY//FRAGILE X SYNDROME//AMERICAN JOURNAL OF MEDICAL GENETICS 53756
2731 2             DOWN SYNDROME//DYRK1A//TS65DN 3262
3268 1                   DOWN SYNDROME//TS65DN//TS65DN MICE 2023
14849 1                   DOWN SYNDROME//ATLANTO OCCIPITAL INSTABILITY//DOWN SYNDROME WESTERN PENN 746
23594 1                   DYRK1A//DYRK2//MINIBRAIN 341
31511 1                   RANBPM//RANBP9//IMMUNEREGULAT 152

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 DOWN SYNDROME authKW 2458816 37% 22% 1207
2 DYRK1A authKW 615049 3% 72% 91
3 TS65DN authKW 611450 2% 93% 70
4 TS65DN MICE authKW 301701 1% 92% 35
5 TRISOMY 21 authKW 257161 5% 16% 173
6 TS1CJE authKW 112976 0% 93% 13
7 RANBPM authKW 106944 1% 57% 20
8 TRISOMY 16 authKW 86634 1% 36% 26
9 TS65DN MOUSE authKW 80884 0% 79% 11
10 DYRK2 authKW 79075 0% 65% 13

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Education, Special 27016 9% 1% 302
2 Rehabilitation 7807 10% 0% 342
3 Neurosciences 4862 24% 0% 785
4 Genetics & Heredity 3405 15% 0% 474
5 Pediatrics 2136 10% 0% 316
6 Clinical Neurology 975 9% 0% 293
7 Developmental Biology 746 3% 0% 111
8 Psychiatry 464 5% 0% 176
9 Biochemistry & Molecular Biology 430 14% 0% 458
10 Geriatrics & Gerontology 334 2% 0% 65

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 DOWN SYNDROME CLIN 48131 0% 86% 6
2 CHILDRENS GUILD FDN SYNDROME PROGRAM 46795 0% 100% 5
3 TAAM 38210 0% 58% 7
4 MARTHA WHITEWAY DAY HOSP 37436 0% 100% 4
5 NEUROPSYCHIAT NEUROPSYCHOL EPILEPTOL 37436 0% 100% 4
6 ELEANOR ROOSEVELT 35100 1% 22% 17
7 CHANGZHOU WOMAN CHILDREN HLTH HOSP 33422 0% 71% 5
8 UPS44 31516 0% 42% 8
9 IMMUNEREGULAT 29947 0% 80% 4
10 UNIT FUNCT AD TAT BIOL BFA 29947 0% 80% 4

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF INTELLECTUAL DISABILITY RESEARCH 56241 3% 6% 108
2 JOURNAL OF NEURAL TRANSMISSION-SUPPLEMENT 21796 1% 5% 43
3 JOURNAL OF MENTAL DEFICIENCY RESEARCH 19284 1% 7% 31
4 DEVELOPMENTAL BRAIN DYSFUNCTION 11522 0% 9% 13
5 JOURNAL OF POLICY AND PRACTICE IN INTELLECTUAL DISABILITIES 10176 1% 6% 18
6 AMERICAN JOURNAL ON MENTAL RETARDATION 8441 1% 3% 31
7 AJIDD-AMERICAN JOURNAL ON INTELLECTUAL AND DEVELOPMENTAL DISABILITIES 6742 0% 5% 14
8 INTERNATIONAL REVIEW OF RESEARCH IN MENTAL RETARDATION 5012 0% 5% 11
9 BRITISH JOURNAL OF DEVELOPMENTAL DISABILITIES 3337 0% 4% 9
10 RESEARCH IN DEVELOPMENTAL DISABILITIES 2852 1% 1% 31

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class		 LCSH search Wikipedia search
1 DOWN SYNDROME 2458816 37% 22% 1207 Search DOWN+SYNDROME Search DOWN+SYNDROME
2 DYRK1A 615049 3% 72% 91 Search DYRK1A Search DYRK1A
3 TS65DN 611450 2% 93% 70 Search TS65DN Search TS65DN
4 TS65DN MICE 301701 1% 92% 35 Search TS65DN+MICE Search TS65DN+MICE
5 TRISOMY 21 257161 5% 16% 173 Search TRISOMY+21 Search TRISOMY+21
6 TS1CJE 112976 0% 93% 13 Search TS1CJE Search TS1CJE
7 RANBPM 106944 1% 57% 20 Search RANBPM Search RANBPM
8 TRISOMY 16 86634 1% 36% 26 Search TRISOMY+16 Search TRISOMY+16
9 TS65DN MOUSE 80884 0% 79% 11 Search TS65DN+MOUSE Search TS65DN+MOUSE
10 DYRK2 79075 0% 65% 13 Search DYRK2 Search DYRK2

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 CONTESTABILE, A , BENFENATI, F , GASPARINI, L , (2010) COMMUNICATION BREAKS-DOWN: FROM NEURODEVELOPMENT DEFECTS TO COGNITIVE DISABILITIES IN DOWN SYNDROME.PROGRESS IN NEUROBIOLOGY. VOL. 91. ISSUE 1. P. 1-22 199 70% 46
2 RUEDA, N , FLOREZ, J , MARTINEZ-CUE, C , (2012) MOUSE MODELS OF DOWN SYNDROME AS A TOOL TO UNRAVEL THE CAUSES OF MENTAL DISABILITIES.NEURAL PLASTICITY. VOL. . ISSUE . P. - 174 67% 31
3 DUCHON, A , HERAULT, Y , (2016) DYRK1A, A DOSAGE-SENSITIVE GENE INVOLVED IN NEURODEVELOPMENTAL DISORDERS, IS A TARGET FOR DRUG DEVELOPMENT IN DOWN SYNDROME.FRONTIERS IN BEHAVIORAL NEUROSCIENCE. VOL. 10. ISSUE . P. - 160 76% 0
4 BARTESAGHI, R , GUIDI, S , CIANI, E , (2011) IS IT POSSIBLE TO IMPROVE NEURODEVELOPMENTAL ABNORMALITIES IN DOWN SYNDROME ?.REVIEWS IN THE NEUROSCIENCES. VOL. 22. ISSUE 4. P. 419-455 193 63% 14
5 RACHIDI, M , LOPES, C , (2010) MOLECULAR AND CELLULAR MECHANISMS ELUCIDATING NEUROCOGNITIVE BASIS OF FUNCTIONAL IMPAIRMENTS ASSOCIATED WITH INTELLECTUAL DISABILITY IN DOWN SYNDROME.AJIDD-AMERICAN JOURNAL ON INTELLECTUAL AND DEVELOPMENTAL DISABILITIES. VOL. 115. ISSUE 2. P. 83-112 133 68% 11
6 RACHIDI, M , LOPES, C , (2007) MENTAL RETARDATION IN DOWN SYNDROME: FROM GENE DOSAGE IMBALANCE TO MOLECULAR AND CELLULAR MECHANISMS.NEUROSCIENCE RESEARCH. VOL. 59. ISSUE 4. P. 349 -369 134 69% 39
7 DIERSSEN, M , (2012) DOWN SYNDROME: THE BRAIN IN TRISOMIC MODE.NATURE REVIEWS NEUROSCIENCE. VOL. 13. ISSUE 12. P. 844 -858 113 68% 33
8 CREAU, N , (2012) MOLECULAR AND CELLULAR ALTERATIONS IN DOWN SYNDROME: TOWARD THE IDENTIFICATION OF TARGETS FOR THERAPEUTICS.NEURAL PLASTICITY. VOL. . ISSUE . P. - 111 78% 0
9 HERAULT, Y , DUCHON, A , VELOT, E , MARECHAL, D , BRAULT, V , (2012) THE IN VIVO DOWN SYNDROME GENOMIC LIBRARY IN MOUSE.DOWN SYNDROME: FROM UNDERSTANDING THE NEUROBIOLOGY TO THERAPY. VOL. 197. ISSUE . P. 169 -197 130 64% 9
10 COSTA, ACS , SCOTT-MCKEAN, JJ , (2013) PROSPECTS FOR IMPROVING BRAIN FUNCTION IN INDIVIDUALS WITH DOWN SYNDROME.CNS DRUGS. VOL. 27. ISSUE 9. P. 679-702 116 64% 20

Classes with closest relation at Level 2


Rank Class id link
1 3091 WILLIAMS SYNDROME//WILLIAMS BEUREN SYNDROME//SUPRAVALVULAR AORTIC STENOSIS
2 1334 INTELLECTUAL DISABILITY//EDUCATION, SPECIAL//JOURNAL OF INTELLECTUAL DISABILITY RESEARCH
3 4032 ARTIFICIAL FOOD COLORINGS//ARTIFICIAL FOOD DYES//ARTIFICIAL FOOD COLORS
4 2171 EBSTEINS ANOMALY//COR TRIATRIATUM//JOURNAL OF VETERINARY CARDIOLOGY
5 35 ALZHEIMERS DISEASE//AMYLOID PRECURSOR PROTEIN//TAU
6 395 GENETICS & HEREDITY//ANNALES DE GENETIQUE//HOLOPROSENCEPHALY
7 2159 PIN1//CYCLOPHILIN//CALCINEURIN
8 2040 TOPICS IN EARLY CHILDHOOD SPECIAL EDUCATION//EDUCATION, SPECIAL//JOURNAL OF EARLY INTERVENTION
9 2900 PRADER WILLI SYNDROME//ANGELMAN SYNDROME//UBE3A
10 1566 FRAGILE X SYNDROME//RETT SYNDROME//FRAGILE X

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