Class information for:
Level 1: BIOTIN SYNTHASE//BIOTIN BIOSYNTHESIS//RADICAL SAM

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
14459 768 41.1 76%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
5 4 CHEMISTRY, ORGANIC//CHEMISTRY, INORGANIC & NUCLEAR//CHEMISTRY, MULTIDISCIPLINARY 1745167
569 3       HYDROGENASE//FERREDOXIN//FEFE HYDROGENASE 16869
1262 2             HYDROGENASE//FERREDOXIN//FEFE HYDROGENASE 8811
14459 1                   BIOTIN SYNTHASE//BIOTIN BIOSYNTHESIS//RADICAL SAM 768

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOTIN SYNTHASE authKW 836649 3% 96% 22
2 BIOTIN BIOSYNTHESIS authKW 762714 4% 71% 27
3 RADICAL SAM authKW 477086 2% 67% 18
4 DETHIOBIOTIN SYNTHETASE authKW 282723 1% 89% 8
5 HYDF authKW 238549 1% 100% 6
6 ASTROBIOL BIOGEOCATALYSIS address 220784 2% 29% 19
7 RADICAL SAM ENZYME authKW 212038 1% 67% 8
8 BIOB authKW 198791 1% 100% 5
9 AMICLENOMYCIN authKW 159033 1% 100% 4
10 BIOTIN SYNTHESIS authKW 159033 1% 100% 4

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Biochemistry & Molecular Biology 4565 63% 0% 482
2 Biophysics 908 13% 0% 102
3 Chemistry, Multidisciplinary 407 17% 0% 133
4 Microbiology 96 6% 0% 47
5 Biotechnology & Applied Microbiology 87 6% 0% 46
6 Biochemical Research Methods 65 4% 0% 31
7 Cell Biology 47 6% 0% 47
8 Chemistry, Organic 33 5% 0% 36
9 Chemistry, Inorganic & Nuclear 18 3% 0% 22
10 Chemistry, Applied 7 2% 0% 13

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ASTROBIOL BIOGEOCATALYSIS 220784 2% 29% 19
2 CHIM ORGAN BIOL 131416 2% 18% 18
3 UMR CEA CNRS UJF 5249 127225 1% 80% 4
4 CHEMSYBIO 106019 1% 67% 4
5 SCIB LRM 89454 0% 75% 3
6 STELLAR CHANCE S 905B 89454 0% 75% 3
7 DBMSCB CHIM BIOCHIM REDOX BIOL 79516 0% 100% 2
8 MICALIS CHEMSYBIO 79516 0% 100% 2
9 UPR 910 79516 0% 100% 2
10 CBDBMS CHIM BIOCHIM REDOX BIOL 53010 0% 67% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOCHEMISTRY 6822 13% 0% 96
2 CURRENT OPINION IN CHEMICAL BIOLOGY 5391 2% 1% 16
3 JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY 3851 2% 1% 14
4 BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS 3635 2% 1% 17
5 NATURE CHEMICAL BIOLOGY 2335 1% 1% 9
6 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2095 9% 0% 71
7 JOURNAL OF BIOLOGICAL CHEMISTRY 1238 9% 0% 71
8 FEBS LETTERS 726 4% 0% 28
9 BIOMEDICAL MASS SPECTROMETRY 556 0% 0% 3
10 ADVANCES IN PROTEIN CHEMISTRY 482 0% 1% 2

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 BIOTIN SYNTHASE 836649 3% 96% 22 Search BIOTIN+SYNTHASE Search BIOTIN+SYNTHASE
2 BIOTIN BIOSYNTHESIS 762714 4% 71% 27 Search BIOTIN+BIOSYNTHESIS Search BIOTIN+BIOSYNTHESIS
3 RADICAL SAM 477086 2% 67% 18 Search RADICAL+SAM Search RADICAL+SAM
4 DETHIOBIOTIN SYNTHETASE 282723 1% 89% 8 Search DETHIOBIOTIN+SYNTHETASE Search DETHIOBIOTIN+SYNTHETASE
5 HYDF 238549 1% 100% 6 Search HYDF Search HYDF
6 RADICAL SAM ENZYME 212038 1% 67% 8 Search RADICAL+SAM+ENZYME Search RADICAL+SAM+ENZYME
7 BIOB 198791 1% 100% 5 Search BIOB Search BIOB
8 AMICLENOMYCIN 159033 1% 100% 4 Search AMICLENOMYCIN Search AMICLENOMYCIN
9 BIOTIN SYNTHESIS 159033 1% 100% 4 Search BIOTIN+SYNTHESIS Search BIOTIN+SYNTHESIS
10 H CLUSTER BIOSYNTHESIS 159033 1% 100% 4 Search H+CLUSTER+BIOSYNTHESIS Search H+CLUSTER+BIOSYNTHESIS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 BRODERICK, JB , DUFFUS, BR , DUSCHENE, KS , SHEPARD, EM , (2014) RADICAL S-ADENOSYLMETHIONINE ENZYMES.CHEMICAL REVIEWS. VOL. 114. ISSUE 8. P. 4229 -4317 264 45% 85
2 FREY, PA , HEGEMAN, AD , RUZICKA, FJ , (2008) THE RADICAL SAM SUPERFAMILY.CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY. VOL. 43. ISSUE 1. P. 63 -88 99 63% 262
3 CHALLAND, MR , DRIESENER, RC , ROACH, PL , (2011) RADICAL S-ADENOSYLMETHIONINE ENZYMES: MECHANISM, CONTROL AND FUNCTION.NATURAL PRODUCT REPORTS. VOL. 28. ISSUE 10. P. 1696 -1721 112 73% 18
4 VEY, JL , DRENNAN, CL , (2011) STRUCTURAL INSIGHTS INTO RADICAL GENERATION BY THE RADICAL SAM SUPERFAMILY.CHEMICAL REVIEWS. VOL. 111. ISSUE 4. P. 2487 -2506 92 72% 81
5 FREY, PA , MAGNUSSON, OT , (2003) S-ADENOSYLMETHIONINE: A WOLF IN SHEEP'S CLOTHING, OR A RICH MAN'S ADENOSYLCOBALAMIN?.CHEMICAL REVIEWS. VOL. 103. ISSUE 6. P. 2129-2148 104 73% 134
6 LANZ, ND , BOOKER, SJ , (2015) AUXILIARY IRON-SULFUR COFACTORS IN RADICAL SAM ENZYMES.BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH. VOL. 1853. ISSUE 6. P. 1316 -1334 90 60% 7
7 SHISLER, KA , BRODERICK, JB , (2014) GLYCYL RADICAL ACTIVATING ENZYMES: STRUCTURE, MECHANISM, AND SUBSTRATE INTERACTIONS.ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. VOL. 546. ISSUE . P. 64 -71 64 78% 17
8 SHISLER, KA , BRODERICK, JB , (2012) EMERGING THEMES IN RADICAL SAM CHEMISTRY.CURRENT OPINION IN STRUCTURAL BIOLOGY. VOL. 22. ISSUE 6. P. 701-710 59 86% 18
9 LANZ, ND , BOOKER, SJ , (2012) IDENTIFICATION AND FUNCTION OF AUXILIARY IRON-SULFUR CLUSTERS IN RADICAL SAM ENZYMES.BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS. VOL. 1824. ISSUE 11. P. 1196 -1212 89 53% 26
10 WANG, JR , WOLDRING, RP , ROMAN-MELENDEZ, GD , MCCLAIN, AM , ALZUA, BR , MARSH, ENG , (2014) RECENT ADVANCES IN RADICAL SAM ENZYMOLOGY: NEW STRUCTURES AND MECHANISMS.ACS CHEMICAL BIOLOGY. VOL. 9. ISSUE 9. P. 1929 -1938 51 85% 16

Classes with closest relation at Level 1


Rank Class id link
1 19805 PERCHLORIC ACID SOLUBLE PROTEIN//THIAMINE BINDING PROTEIN//THIAMINE BIOSYNTHESIS
2 14819 BIOTIN PROTEIN LIGASE//PYRUVATE CARBOXYLASE//BIRA
3 5027 RIBONUCLEOTIDE REDUCTASE//P53R2//TRIMIDOX
4 20833 THIOPEPTIDES//NOSIHEPTIDE//NOCATHIACIN
5 2834 COENZYME B 12//COBALOXIME//ADENOSYLCOBALAMIN
6 21261 2 DEOXY SCYLLO INOSOSE SYNTHASE//BUTIROSIN//STREPTOMYCES KANAMYCETICUS
7 27206 STREPTOTHRICIN//TUBERACTINOMYCIN//STREPTOTHRICIN ACETYLTRANSFERASE
8 4218 RUBREDOXIN//FERREDOXIN//HIGH POTENTIAL IRON SULFUR PROTEIN
9 18960 C P LYASE//CARBON PHOSPHORUS BOND//PHN OPERON
10 22226 THREONINE DEHYDROGENASE//L THREONINE DEHYDROGENASE//TDC OPERON

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