Class information for:
Level 1: BIOTIN PROTEIN LIGASE//PYRUVATE CARBOXYLASE//BIRA

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
14819 748 32.8 65%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
389 3       PEROXISOME//CARNITINE//JOURNAL OF INHERITED METABOLIC DISEASE 30841
2805 2             BIOTIN//BIOTINIDASE DEFICIENCY//BIOTINIDASE 3081
14819 1                   BIOTIN PROTEIN LIGASE//PYRUVATE CARBOXYLASE//BIRA 748

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOTIN PROTEIN LIGASE authKW 566778 3% 73% 19
2 PYRUVATE CARBOXYLASE authKW 446335 6% 23% 47
3 BIRA authKW 318829 2% 46% 17
4 PYRUVATE CARBOXYLASE DEFICIENCY authKW 275539 1% 75% 9
5 BIOL STRUCT ORG address 235198 1% 52% 11
6 BIOTIN CARBOXYLASE authKW 217700 2% 44% 12
7 CARBOXYLTRANSFERASE authKW 206650 1% 56% 9
8 BIOTIN CARBOXYL CARRIER PROTEIN authKW 183687 1% 50% 9
9 TRANSCARBOXYLASE authKW 181835 1% 64% 7
10 BIOTIN DEPENDENT ENZYME authKW 170087 1% 83% 5

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Biochemistry & Molecular Biology 3972 60% 0% 446
2 Biophysics 642 11% 0% 86
3 Biochemical Research Methods 556 10% 0% 74
4 Microbiology 267 9% 0% 69
5 Genetics & Heredity 147 7% 0% 54
6 Biotechnology & Applied Microbiology 102 6% 0% 48
7 Cell Biology 84 7% 0% 56
8 Chemistry, Organic 60 6% 0% 43
9 Chemistry, Multidisciplinary 19 7% 0% 49
10 Chemistry, Analytical 14 3% 0% 26

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOL STRUCT ORG 235198 1% 52% 11
2 MOL METAB GRP 73470 1% 30% 6
3 CHEM LIFE SCI B103 42197 1% 9% 11
4 AVENTIS UMR 1932 40821 0% 100% 1
5 CAMBRIDGE DIABET ENDOCRINOL METAB 40821 0% 100% 1
6 CHEM MRC UNIT PROT FUNCT DESIGN 40821 0% 100% 1
7 CPTP INNOVAT THER EUT ONCOL MOL 40821 0% 100% 1
8 GENERAT MONOCLONAL ANTIBODIES 40821 0% 100% 1
9 GENET MOLUNIT U781 40821 0% 100% 1
10 LERHSTUHL ZELLBIOL PFLANZENPHYSIOL 40821 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOCHEMISTRY 3272 9% 0% 66
2 PROTEIN SCIENCE 1641 2% 0% 16
3 BIOMOLECULAR ENGINEERING 1091 0% 1% 3
4 JOURNAL OF INHERITED METABOLIC DISEASE 1073 1% 0% 11
5 JOURNAL OF BIOLOGICAL CHEMISTRY 957 8% 0% 62
6 PROTEIN EXPRESSION AND PURIFICATION 865 1% 0% 10
7 JOURNAL OF MOLECULAR BIOLOGY 669 3% 0% 20
8 ANALYTICAL BIOCHEMISTRY 613 2% 0% 17
9 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 589 2% 0% 16
10 BIOCHEMICAL JOURNAL 584 3% 0% 21

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 BIOTIN PROTEIN LIGASE 566778 3% 73% 19 Search BIOTIN+PROTEIN+LIGASE Search BIOTIN+PROTEIN+LIGASE
2 PYRUVATE CARBOXYLASE 446335 6% 23% 47 Search PYRUVATE+CARBOXYLASE Search PYRUVATE+CARBOXYLASE
3 BIRA 318829 2% 46% 17 Search BIRA Search BIRA
4 PYRUVATE CARBOXYLASE DEFICIENCY 275539 1% 75% 9 Search PYRUVATE+CARBOXYLASE+DEFICIENCY Search PYRUVATE+CARBOXYLASE+DEFICIENCY
5 BIOTIN CARBOXYLASE 217700 2% 44% 12 Search BIOTIN+CARBOXYLASE Search BIOTIN+CARBOXYLASE
6 CARBOXYLTRANSFERASE 206650 1% 56% 9 Search CARBOXYLTRANSFERASE Search CARBOXYLTRANSFERASE
7 BIOTIN CARBOXYL CARRIER PROTEIN 183687 1% 50% 9 Search BIOTIN+CARBOXYL+CARRIER+PROTEIN Search BIOTIN+CARBOXYL+CARRIER+PROTEIN
8 TRANSCARBOXYLASE 181835 1% 64% 7 Search TRANSCARBOXYLASE Search TRANSCARBOXYLASE
9 BIOTIN DEPENDENT ENZYME 170087 1% 83% 5 Search BIOTIN+DEPENDENT+ENZYME Search BIOTIN+DEPENDENT+ENZYME
10 BIOTIN REPRESSOR 130627 1% 80% 4 Search BIOTIN+REPRESSOR Search BIOTIN+REPRESSOR

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 ADINA-ZADA, A , ZECZYCKI, TN , ATTWOOD, PV , (2012) REGULATION OF THE STRUCTURE AND ACTIVITY OF PYRUVATE CARBOXYLASE BY ACETYL COA.ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. VOL. 519. ISSUE 2. P. 118 -130 45 92% 19
2 MENEFEE, AL , ZECZYCKI, TN , (2014) NEARLY 50 YEARS IN THE MAKING: DEFINING THE CATALYTIC MECHANISM OF THE MULTIFUNCTIONAL ENZYME, PYRUVATE CARBOXYLASE.FEBS JOURNAL. VOL. 281. ISSUE 5. P. 1333 -1354 49 80% 4
3 JITRAPAKDEE, S , ST MAURICE, M , RAYMENT, I , CLELAND, WW , WALLACE, JC , ATTWOOD, PV , (2008) STRUCTURE, MECHANISM AND REGULATION OF PYRUVATE CARBOXYLASE.BIOCHEMICAL JOURNAL. VOL. 413. ISSUE . P. 369-387 71 51% 111
4 LIETZAN, AD , ST MAURICE, M , (2014) FUNCTIONALLY DIVERSE BIOTIN-DEPENDENT ENZYMES WITH OXALOACETATE DECARBOXYLASE ACTIVITY.ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. VOL. 544. ISSUE . P. 75 -86 56 64% 3
5 BROUSSARD, TC , KOBE, MJ , PAKHOMOVA, S , NEAU, DB , PRICE, AE , CHAMPION, TS , WALDROP, GL , (2013) THE THREE-DIMENSIONAL STRUCTURE OF THE BIOTIN CARBOXYLASE-BIOTIN CARBOXYL CARRIER PROTEIN COMPLEX OF E. COLI ACETYL-COA CARBOXYLASE.STRUCTURE. VOL. 21. ISSUE 4. P. 650 -657 34 83% 5
6 WALDROP, GL , HOLDEN, HM , ST MAURICE, M , (2012) THE ENZYMES OF BIOTIN DEPENDENT CO2 METABOLISM: WHAT STRUCTURES REVEAL ABOUT THEIR REACTION MECHANISMS.PROTEIN SCIENCE. VOL. 21. ISSUE 11. P. 1597 -1619 47 57% 14
7 JITRAPAKDEE, S , WALLACE, JC , (1999) STRUCTURE, FUNCTION AND REGULATION OF PYRUVATE CARBOXYLASE.BIOCHEMICAL JOURNAL. VOL. 340. ISSUE . P. 1 -16 72 46% 142
8 ZECZYCKI, TN , MENEFEE, AL , ADINA-ZADA, A , JITRAPAKDEE, S , SURINYA, KH , WALLACE, JC , ATTWOOD, PV , ST MAURICE, M , CLELAND, WW , (2011) NOVEL INSIGHTS INTO THE BIOTIN CARBOXYLASE DOMAIN REACTIONS OF PYRUVATE CARBOXYLASE FROM RHIZOBIUM ETLI.BIOCHEMISTRY. VOL. 50. ISSUE 45. P. 9724-9737 35 81% 3
9 JITRAPAKDEE, S , WALLACE, JC , (2003) THE BIOTIN ENZYME FAMILY: CONSERVED STRUCTURAL MOTIFS AND DOMAIN REARRANGEMENTS.CURRENT PROTEIN & PEPTIDE SCIENCE. VOL. 4. ISSUE 3. P. 217-229 46 63% 59
10 LIETZAN, AD , MENEFEE, AL , ZECZYCKI, TN , KUMAR, S , ATTWOOD, PV , WALLACE, JC , CLELAND, WW , ST MAURICE, M , (2011) INTERACTION BETWEEN THE BIOTIN CARBOXYL CARRIER DOMAIN AND THE BIOTIN CARBOXYLASE DOMAIN IN PYRUVATE CARBOXYLASE FROM RHIZOBIUM ETLI.BIOCHEMISTRY. VOL. 50. ISSUE 45. P. 9708 -9723 38 66% 6

Classes with closest relation at Level 1


Rank Class id link
1 8358 BIOTINIDASE DEFICIENCY//BIOTIN//BIOTINIDASE
2 17998 ACETYL COA CARBOXYLASE//SORAPHEN A//SORAPHEN
3 14459 BIOTIN SYNTHASE//BIOTIN BIOSYNTHESIS//RADICAL SAM
4 15869 AVIDIN//STREPTAVIDIN//BIOTIN BINDING PROTEIN
5 18868 MALONATE DECARBOXYLASE//ACIDAMINOCOCCUS FERMENTANS//OXALOACETATE DECARBOXYLASE
6 7264 HERBICIDE RESISTANCE//ACCASE//ACCASE INHIBITORS
7 4028 PYRUVATE DEHYDROGENASE COMPLEX//DIHYDROLIPOAMIDE DEHYDROGENASE//LIPOYL DOMAIN
8 36910 SCI ENGN SETAGAYA KU//6 AMINO 5 NITROSOPYRIMIDINES//ACETONITRILE DEUTERIUM OXIDE SOLVENT
9 27635 COMPUTATIONAL CHEMICAL KINETICS//GEM DIMETHYL EFFECT//4 HYDROXYTHIAZOLE
10 23083 D BIOTIN//FUDAN DSM JOINT SYNTHET METHOD CHIRAL TECHN//VITAMIN H

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