Class information for:
Level 2: BIOTIN//BIOTINIDASE DEFICIENCY//BIOTINIDASE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
2805 3081 30.4 62%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
389 3       PEROXISOME//CARNITINE//JOURNAL OF INHERITED METABOLIC DISEASE 30841
2805 2             BIOTIN//BIOTINIDASE DEFICIENCY//BIOTINIDASE 3081
8358 1                   BIOTINIDASE DEFICIENCY//BIOTIN//BIOTINIDASE 1262
14819 1                   BIOTIN PROTEIN LIGASE//PYRUVATE CARBOXYLASE//BIRA 748
15869 1                   AVIDIN//STREPTAVIDIN//BIOTIN BINDING PROTEIN 687
24614 1                   LIPID LAYER CRYSTALLIZATION//3D DENSITY MAPS//ICHTEN GRENZFLACHEN ISG 4 306
36558 1                   STRAINS OF GUINEA PIGS//HYBROTEC//1 3 DIAZA 2 OXOPHENOXAZINE TC DEGREES 78

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOTIN authKW 1296251 15% 29% 452
2 BIOTINIDASE DEFICIENCY authKW 636189 2% 88% 73
3 BIOTINIDASE authKW 544132 2% 89% 62
4 HOLOCARBOXYLASE SYNTHETASE authKW 525178 2% 100% 53
5 BIOTIN DEFICIENCY authKW 352327 1% 83% 43
6 AVIDIN authKW 237353 4% 22% 111
7 STREPTAVIDIN authKW 221717 4% 19% 120
8 MULTIPLE CARBOXYLASE DEFICIENCY authKW 191833 1% 88% 22
9 PYRUVATE CARBOXYLASE authKW 176512 2% 30% 60
10 BIOTIN PROTEIN LIGASE authKW 152437 1% 77% 20

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Biochemistry & Molecular Biology 5415 37% 0% 1129
2 Nutrition & Dietetics 3347 9% 0% 284
3 Biochemical Research Methods 2680 11% 0% 327
4 Biophysics 1706 9% 0% 292
5 Genetics & Heredity 729 8% 0% 239
6 Medicine, Research & Experimental 446 6% 0% 174
7 Endocrinology & Metabolism 384 6% 0% 171
8 Medical Laboratory Technology 373 2% 0% 64
9 Chemistry, Analytical 369 6% 0% 191
10 Pediatrics 347 5% 0% 144

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 UNIDAD GENET NUTR 95098 1% 40% 24
2 BIOL STRUCT ORG 67937 0% 57% 12
3 DIETARY ENVIRONM ANAL 48777 0% 62% 8
4 NUTR HLTH SCI 28203 2% 5% 61
5 ICHTEN GRENZFLACHEN ISG 4 19818 0% 100% 2
6 MED GENET BIOCHEM GENET 19818 0% 100% 2
7 MED VIRGINIA HUMAN GENETPOB 33MCV STN 19818 0% 100% 2
8 PEDIAT BIOCHEM MOL BIOPHYS 19818 0% 100% 2
9 WOLFSON PL STRUCT BIOL 19061 1% 11% 17
10 NUTRAOBA KU 17834 0% 60% 3

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF INHERITED METABOLIC DISEASE 13209 3% 2% 78
2 BIOMOLECULAR ENGINEERING 6627 0% 4% 15
3 JOURNAL OF NUTRITIONAL BIOCHEMISTRY 5351 1% 1% 42
4 MOLECULAR GENETICS AND METABOLISM 5014 1% 1% 40
5 JOURNAL OF NUTRITION 4937 3% 1% 82
6 ADVANCES IN BIOPHYSICS 3419 0% 6% 6
7 INTERNATIONAL JOURNAL FOR VITAMIN AND NUTRITION RESEARCH 2462 1% 1% 22
8 ANALYTICAL BIOCHEMISTRY 2166 2% 0% 65
9 METHODS IN ENZYMOLOGY 2018 2% 0% 59
10 JOURNAL OF IMMUNOLOGICAL METHODS 1740 1% 0% 42

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 BIOTIN 1296251 15% 29% 452 Search BIOTIN Search BIOTIN
2 BIOTINIDASE DEFICIENCY 636189 2% 88% 73 Search BIOTINIDASE+DEFICIENCY Search BIOTINIDASE+DEFICIENCY
3 BIOTINIDASE 544132 2% 89% 62 Search BIOTINIDASE Search BIOTINIDASE
4 HOLOCARBOXYLASE SYNTHETASE 525178 2% 100% 53 Search HOLOCARBOXYLASE+SYNTHETASE Search HOLOCARBOXYLASE+SYNTHETASE
5 BIOTIN DEFICIENCY 352327 1% 83% 43 Search BIOTIN+DEFICIENCY Search BIOTIN+DEFICIENCY
6 AVIDIN 237353 4% 22% 111 Search AVIDIN Search AVIDIN
7 STREPTAVIDIN 221717 4% 19% 120 Search STREPTAVIDIN Search STREPTAVIDIN
8 MULTIPLE CARBOXYLASE DEFICIENCY 191833 1% 88% 22 Search MULTIPLE+CARBOXYLASE+DEFICIENCY Search MULTIPLE+CARBOXYLASE+DEFICIENCY
9 PYRUVATE CARBOXYLASE 176512 2% 30% 60 Search PYRUVATE+CARBOXYLASE Search PYRUVATE+CARBOXYLASE
10 BIOTIN PROTEIN LIGASE 152437 1% 77% 20 Search BIOTIN+PROTEIN+LIGASE Search BIOTIN+PROTEIN+LIGASE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 LAITINEN, OH , HYTONEN, VP , NORDLUND, HR , KULOMAA, MS , (2006) GENETICALLY ENGINEERED AVIDINS AND STREPTAVIDINS.CELLULAR AND MOLECULAR LIFE SCIENCES. VOL. 63. ISSUE 24. P. 2992-3017 104 81% 137
2 WOLF, B , (2016) BIOTINIDASE DEFICIENCY AND OUR CHAMPAGNE LEGACY.GENE. VOL. 589. ISSUE 2. P. 142 -150 84 98% 0
3 ZEMPLENI, J , WIJERATNE, SSK , HASSAN, YI , (2009) BIOTIN.BIOFACTORS. VOL. 35. ISSUE 1. P. 36-46 80 91% 64
4 MCMAHON, RJ , (2002) BIOTIN IN METABOLISM AND MOLECULAR BIOLOGY.ANNUAL REVIEW OF NUTRITION. VOL. 22. ISSUE . P. 221-239 92 96% 62
5 WOLF, B , (2012) BIOTINIDASE DEFICIENCY: "IF YOU HAVE TO HAVE AN INHERITED METABOLIC DISEASE, THIS IS THE ONE TO HAVE".GENETICS IN MEDICINE. VOL. 14. ISSUE 6. P. 565-575 66 100% 18
6 WOLF, B , (2011) THE NEUROLOGY OF BIOTINIDASE DEFICIENCY.MOLECULAR GENETICS AND METABOLISM. VOL. 104. ISSUE 1-2. P. 27 -34 59 94% 24
7 PENDINI, NR , BAILEY, LM , BOOKER, GW , WILCE, MC , WALLACE, JC , POLYAK, SW , (2008) MICROBIAL BIOTIN PROTEIN LIGASES AID IN UNDERSTANDING HOLOCARBOXYLASE SYNTHETASE DEFICIENCY.BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS. VOL. 1784. ISSUE 7-8. P. 973-982 78 82% 6
8 COWAN, TM , BLITZER, MG , WOLF, B , (2010) TECHNICAL STANDARDS AND GUIDELINES FOR THE DIAGNOSIS OF BIOTINIDASE DEFICIENCY.GENETICS IN MEDICINE. VOL. 12. ISSUE 7. P. 464-470 54 98% 15
9 ADINA-ZADA, A , ZECZYCKI, TN , ATTWOOD, PV , (2012) REGULATION OF THE STRUCTURE AND ACTIVITY OF PYRUVATE CARBOXYLASE BY ACETYL COA.ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. VOL. 519. ISSUE 2. P. 118 -130 45 92% 19
10 ZEMPLENI, J , MOCK, DM , (1999) BIOTIN BIOCHEMISTRY AND HUMAN REQUIREMENTS.JOURNAL OF NUTRITIONAL BIOCHEMISTRY. VOL. 10. ISSUE 3. P. 128 -138 71 85% 51

Classes with closest relation at Level 2


Rank Class id link
1 2144 JOURNAL OF INHERITED METABOLIC DISEASE//NEWBORN SCREENING//METHYLMALONIC ACIDEMIA
2 2868 PYRUVATE DEHYDROGENASE COMPLEX//NONKETOTIC HYPERGLYCINEMIA//DIHYDROLIPOAMIDE DEHYDROGENASE
3 1475 THIAMINE//THIAMINE DEFICIENCY//WERNICKES ENCEPHALOPATHY
4 3076 PEPTIDE DEFORMYLASE//ENOYL ACP REDUCTASE//ACYL CARRIER PROTEIN
5 2141 FATTY ACID SYNTHASE//LIVER X RECEPTOR//LXR
6 2591 HETEROPHILIC ANTIBODIES//HETEROPHILE ANTIBODIES//JOURNAL OF IMMUNOLOGICAL METHODS
7 2596 ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY//ACTA CRYSTALLOGRAPHICA SECTION A//ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY
8 1537 CELL FREE PROTEIN SYNTHESIS//INTEIN//PROTEIN SPLICING
9 3395 PKAN//NBIA//PANTOTHENATE KINASE
10 1834 PHAGE DISPLAY//ANTIBODY ENGINEERING//BISPECIFIC ANTIBODY

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