Class information for:
Level 2: PEPTIDE DEFORMYLASE//ENOYL ACP REDUCTASE//ACYL CARRIER PROTEIN

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
3076 2395 39.7 78%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
389 3       PEROXISOME//CARNITINE//JOURNAL OF INHERITED METABOLIC DISEASE 30841
3076 2             PEPTIDE DEFORMYLASE//ENOYL ACP REDUCTASE//ACYL CARRIER PROTEIN 2395
7161 1                   ENOYL ACP REDUCTASE//ACYL CARRIER PROTEIN//FABH 1398
19843 1                   ESSENTIAL GENES//TN SEQ//SUBTRACTIVE GENOMICS 487
23535 1                   PEPTIDE DEFORMYLASE//PEPTIDE DEFORMYLASE INHIBITORS//DEFORMYLASE 343
30519 1                   PLATENSIMYCIN//PLATENCIN//STREPTOMYCES PLATENSIS 167

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PEPTIDE DEFORMYLASE authKW 633611 3% 76% 65
2 ENOYL ACP REDUCTASE authKW 459570 2% 69% 52
3 ACYL CARRIER PROTEIN authKW 415436 3% 44% 74
4 FABH authKW 334701 1% 82% 32
5 PLATENSIMYCIN authKW 331897 1% 96% 27
6 FABI authKW 291666 1% 74% 31
7 FATTY ACID BIOSYNTHESIS authKW 271047 3% 30% 71
8 FABH INHIBITORS authKW 206511 1% 90% 18
9 ENOYL REDUCTASE authKW 200387 1% 60% 26
10 PLATENCIN authKW 165722 1% 100% 13

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Biochemistry & Molecular Biology 6605 45% 0% 1066
2 Microbiology 5875 22% 0% 516
3 Chemistry, Medicinal 3684 12% 0% 292
4 Biophysics 1854 11% 0% 263
5 Biochemical Research Methods 777 7% 0% 165
6 Biotechnology & Applied Microbiology 765 9% 0% 214
7 Chemistry, Organic 670 9% 0% 218
8 Pharmacology & Pharmacy 551 11% 0% 271
9 Crystallography 162 3% 0% 69
10 Genetics & Heredity 123 4% 0% 107

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SECT PHYSIOL LIPID METAB 90649 0% 89% 8
2 CHEM BIOL DRUG DISCOVERY 77870 2% 17% 36
3 INFECT DIS THER EUT AREA 65559 0% 86% 6
4 MOL BIOL GENET UNIT 64070 2% 13% 40
5 PROMEDITECH LTD 50991 0% 100% 4
6 OILS 39833 0% 63% 5
7 MOL BIOL STUDIES 38243 0% 100% 3
8 GUANGDONG PROV PROT FUNCT REGULAT AGR O 31462 0% 22% 11
9 CHEM LIFE SCI B103 31459 1% 15% 17
10 ROCKY MT REG EXCELLENCE 28967 0% 45% 5

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF BACTERIOLOGY 5104 5% 0% 117
2 CURRENT OPINION IN MICROBIOLOGY 3337 1% 1% 22
3 ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 3080 3% 0% 77
4 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 3041 3% 0% 79
5 ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS 2169 1% 1% 23
6 JOURNAL OF BIOLOGICAL CHEMISTRY 1609 6% 0% 147
7 JOURNAL OF ANTIBIOTICS 1561 1% 0% 29
8 ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY 1492 1% 1% 23
9 CARLSBERG RESEARCH COMMUNICATIONS 1342 0% 2% 6
10 PROTEIN SCIENCE 944 1% 0% 22

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 PEPTIDE DEFORMYLASE 633611 3% 76% 65 Search PEPTIDE+DEFORMYLASE Search PEPTIDE+DEFORMYLASE
2 ENOYL ACP REDUCTASE 459570 2% 69% 52 Search ENOYL+ACP+REDUCTASE Search ENOYL+ACP+REDUCTASE
3 ACYL CARRIER PROTEIN 415436 3% 44% 74 Search ACYL+CARRIER+PROTEIN Search ACYL+CARRIER+PROTEIN
4 FABH 334701 1% 82% 32 Search FABH Search FABH
5 PLATENSIMYCIN 331897 1% 96% 27 Search PLATENSIMYCIN Search PLATENSIMYCIN
6 FABI 291666 1% 74% 31 Search FABI Search FABI
7 FATTY ACID BIOSYNTHESIS 271047 3% 30% 71 Search FATTY+ACID+BIOSYNTHESIS Search FATTY+ACID+BIOSYNTHESIS
8 FABH INHIBITORS 206511 1% 90% 18 Search FABH+INHIBITORS Search FABH+INHIBITORS
9 ENOYL REDUCTASE 200387 1% 60% 26 Search ENOYL+REDUCTASE Search ENOYL+REDUCTASE
10 PLATENCIN 165722 1% 100% 13 Search PLATENCIN Search PLATENCIN

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 WANG, Y , MA, ST , (2013) RECENT ADVANCES IN INHIBITORS OF BACTERIAL FATTY ACID SYNTHESIS TYPE II (FASII) SYSTEM ENZYMES AS POTENTIAL ANTIBACTERIAL AGENTS.CHEMMEDCHEM. VOL. 8. ISSUE 10. P. 1589-1608 171 83% 17
2 LU, XY , TANG, J , ZHANG, Z , DING, K , (2015) BACTERIAL BETA-KETOACYL-ACYL CARRIER PROTEIN SYNTHASE III (FABH) AS A TARGET FOR NOVEL ANTIBACTERIAL AGENTS DESIGN.CURRENT MEDICINAL CHEMISTRY. VOL. 22. ISSUE 5. P. 651 -667 85 89% 2
3 BELD, J , LEE, DJ , BURKART, MD , (2015) FATTY ACID BIOSYNTHESIS REVISITED: STRUCTURE ELUCIDATION AND METABOLIC ENGINEERING.MOLECULAR BIOSYSTEMS. VOL. 11. ISSUE 1. P. 38 -59 123 53% 11
4 PARSONS, JB , ROCK, C , (2013) BACTERIAL LIPIDS: METABOLISM AND MEMBRANE HOMEOSTASIS.PROGRESS IN LIPID RESEARCH. VOL. 52. ISSUE 3. P. 249 -276 128 42% 64
5 WHITE, SW , ZHENG, J , ZHANG, YM , ROCK, CO , (2005) THE STRUCTURAL BIOLOGY OF TYPE II FATTY ACID BIOSYNTHESIS.ANNUAL REVIEW OF BIOCHEMISTRY. VOL. 74. ISSUE . P. 791 -831 78 62% 371
6 JAIN, R , CHEN, D , WHITE, RJ , PATEL, DV , YUAN, Z , (2005) BACTERIAL PEPTIDE DEFORMYLASE INHIBITORS: A NEW CLASS OF ANTIBACTERIAL AGENTS.CURRENT MEDICINAL CHEMISTRY. VOL. 12. ISSUE 14. P. 1607-1621 65 96% 78
7 CHAN, DI , VOGEL, HJ , (2010) CURRENT UNDERSTANDING OF FATTY ACID BIOSYNTHESIS AND THE ACYL CARRIER PROTEIN.BIOCHEMICAL JOURNAL. VOL. 430. ISSUE . P. 1-19 86 55% 90
8 LU, XY , YOU, QD , (2010) RECENT ADVANCES ON PLATENSIMYCIN: A POTENTIAL ANTIMICROBIAL AGENT.CURRENT MEDICINAL CHEMISTRY. VOL. 17. ISSUE 12. P. 1139 -1155 63 88% 20
9 ZHU, LZ , HAN, YJ , DU, GY , LEE, CS , (2013) A BIFUNCTIONAL LEWIS ACID INDUCED CASCADE CYCLIZATION TO THE TRICYCLIC CORE OF ENT-KAURENOIDS AND ITS APPLICATION TO THE FORMAL SYNTHESIS OF (+/-)-PLATENSIMYCIN.ORGANIC LETTERS. VOL. 15. ISSUE 3. P. 524 -527 63 83% 6
10 FINZEL, K , LEE, DJ , BURKART, MD , (2015) USING MODERN TOOLS TO PROBE THE STRUCTURE-FUNCTION RELATIONSHIP OF FATTY ACID SYNTHASES.CHEMBIOCHEM. VOL. 16. ISSUE 4. P. 528 -547 90 52% 3

Classes with closest relation at Level 2


Rank Class id link
1 2129 OLEOSIN//OIL BODIES//CALEOSIN
2 2794 ERGOTHIONEINE//CATALASE PEROXIDASE//MYCOTHIOL
3 1180 STREPTOMYCES//POLYKETIDES//POLYKETIDE SYNTHASE
4 2141 FATTY ACID SYNTHASE//LIVER X RECEPTOR//LXR
5 3395 PKAN//NBIA//PANTOTHENATE KINASE
6 2596 ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY//ACTA CRYSTALLOGRAPHICA SECTION A//ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY
7 2025 FTSZ//PEPTIDOGLYCAN//BACTERIAL CELL DIVISION
8 3967 PSEUDOPTEROSINS//PSEUDOPTEROGORGIA ELISABETHAE//AZORELLA COMPACTA
9 2486 PYRAZINAMIDE//ISONIAZID//RIFAMPICIN
10 2805 BIOTIN//BIOTINIDASE DEFICIENCY//BIOTINIDASE

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