Class information for:
Level 2: STREPTOMYCES//POLYKETIDES//POLYKETIDE SYNTHASE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
1180 9307 36.6 70%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
3 4 PLANT SCIENCES//AGRONOMY//FOOD SCIENCE & TECHNOLOGY 1882812
243 3       INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY//MICROBIOLOGY//STREPTOMYCES 47319
1180 2             STREPTOMYCES//POLYKETIDES//POLYKETIDE SYNTHASE 9307
1288 1                   POLYKETIDE SYNTHASE//POLYKETIDES//NONRIBOSOMAL PEPTIDE SYNTHETASE 2741
2604 1                   STREPTOMYCES//STREPTOMYCES COELICOLOR//ANTIBIOTIC PRODUCTION 2199
5161 1                   LINEAR PLASMID//LINEAR CHROMOSOME//STREPTOMYCES 1663
6404 1                   STREPTOMYCES CLAVULIGERUS//ACREMONIUM CHRYSOGENUM//CEPHALOSPORIUM ACREMONIUM 1489
25584 1                   BACITRACIN//BACITRACIN RESISTANCE//STABIL TESTING 277
25997 1                   STREPTOMYCES AMBOFACIENS//AERIAL MYCELIA FORMATION//CNRS UA 485 265
27206 1                   STREPTOTHRICIN//TUBERACTINOMYCIN//STREPTOTHRICIN ACETYLTRANSFERASE 235
29163 1                   BIOLOGICAL BASED AGENT//ENZYMATIC TURNOVER NUMBER//ENZYME DIRECTED PEPTIDE SYNTHESIS MODEL 191
33161 1                   DITHIOLOPYRROLONE//SACCHAROTHRIX ALGERIENSIS//ANTILEUKOPENIA 128
33814 1                   TOLYPOCLADIUM INFLATUM//CYCLOSPORIN SYNTHETASE//WHEAT BRAN FLOUR 119

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 STREPTOMYCES authKW 371551 5% 24% 471
2 POLYKETIDES authKW 229874 3% 26% 274
3 POLYKETIDE SYNTHASE authKW 216479 2% 40% 166
4 STREPTOMYCES CLAVULIGERUS authKW 216392 1% 74% 89
5 NONRIBOSOMAL PEPTIDE SYNTHETASE authKW 184429 1% 51% 110
6 STREPTOMYCES COELICOLOR authKW 161832 1% 47% 104
7 ANTIBIOTIC PRODUCTION authKW 126833 1% 58% 67
8 ACREMONIUM CHRYSOGENUM authKW 120523 1% 74% 50
9 ACTINORHODIN authKW 118018 1% 75% 48
10 CLAVULANIC ACID authKW 117162 1% 36% 99

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Microbiology 75045 38% 1% 3513
2 Biotechnology & Applied Microbiology 32654 26% 0% 2399
3 Biochemistry & Molecular Biology 10146 30% 0% 2795
4 Chemistry, Medicinal 2020 5% 0% 475
5 Genetics & Heredity 1765 7% 0% 662
6 Pharmacology & Pharmacy 745 8% 0% 736
7 Chemistry, Organic 517 5% 0% 474
8 Chemistry, Multidisciplinary 391 7% 0% 692
9 Biochemical Research Methods 389 3% 0% 293
10 Biophysics 366 3% 0% 319

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 HBEREICH CHEM BIOCHEM 101490 1% 61% 51
2 AREA MICROBIOL 100223 2% 18% 171
3 CC BIOL AMBIENTALES 52431 0% 50% 32
4 INBIOTEC 49543 0% 66% 23
5 BIOTECNOL LEON 35123 0% 71% 15
6 CIENCIAS BIOL AMBIENTALES 24627 0% 19% 39
7 MU OU ABORAT BIOSCI BIOTECHNOL 23039 0% 47% 15
8 BIOL CHEM MOL PHARMACOL 22043 2% 5% 151
9 COOPERAT DRUG DISCOVERY GRP 20791 0% 32% 20
10 LB GENET 20486 0% 63% 10

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF ANTIBIOTICS 61365 4% 5% 354
2 CHEMISTRY & BIOLOGY 56608 2% 8% 215
3 JOURNAL OF BACTERIOLOGY 33393 6% 2% 587
4 NATURAL PRODUCT REPORTS 23103 1% 7% 100
5 FEMS MICROBIOLOGY LETTERS 20343 3% 2% 317
6 CHEMBIOCHEM 20064 2% 4% 166
7 MICROBIOLOGY-SGM 19391 2% 3% 217
8 JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY 18780 1% 5% 128
9 APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 17107 3% 2% 272
10 MOLECULAR MICROBIOLOGY 16745 3% 2% 249

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 STREPTOMYCES 371551 5% 24% 471 Search STREPTOMYCES Search STREPTOMYCES
2 POLYKETIDES 229874 3% 26% 274 Search POLYKETIDES Search POLYKETIDES
3 POLYKETIDE SYNTHASE 216479 2% 40% 166 Search POLYKETIDE+SYNTHASE Search POLYKETIDE+SYNTHASE
4 STREPTOMYCES CLAVULIGERUS 216392 1% 74% 89 Search STREPTOMYCES+CLAVULIGERUS Search STREPTOMYCES+CLAVULIGERUS
5 NONRIBOSOMAL PEPTIDE SYNTHETASE 184429 1% 51% 110 Search NONRIBOSOMAL+PEPTIDE+SYNTHETASE Search NONRIBOSOMAL+PEPTIDE+SYNTHETASE
6 STREPTOMYCES COELICOLOR 161832 1% 47% 104 Search STREPTOMYCES+COELICOLOR Search STREPTOMYCES+COELICOLOR
7 ANTIBIOTIC PRODUCTION 126833 1% 58% 67 Search ANTIBIOTIC+PRODUCTION Search ANTIBIOTIC+PRODUCTION
8 ACREMONIUM CHRYSOGENUM 120523 1% 74% 50 Search ACREMONIUM+CHRYSOGENUM Search ACREMONIUM+CHRYSOGENUM
9 ACTINORHODIN 118018 1% 75% 48 Search ACTINORHODIN Search ACTINORHODIN
10 CLAVULANIC ACID 117162 1% 36% 99 Search CLAVULANIC+ACID Search CLAVULANIC+ACID

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 LIU, G , CHATER, KF , CHANDRA, G , NIU, GQ , TAN, HR , (2013) MOLECULAR REGULATION OF ANTIBIOTIC BIOSYNTHESIS IN STREPTOMYCES.MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS. VOL. 77. ISSUE 1. P. 112 -143 236 82% 134
2 HAMED, RB , GOMEZ-CASTELLANOS, JR , HENRY, L , DUCHO, C , MCDONOUGH, MA , SCHOFIELD, CJ , (2013) THE ENZYMES OF BETA-LACTAM BIOSYNTHESIS.NATURAL PRODUCT REPORTS. VOL. 30. ISSUE 1. P. 21-107 389 60% 29
3 VAN WEZEL, GP , MCDOWALL, KJ , (2011) THE REGULATION OF THE SECONDARY METABOLISM OF STREPTOMYCES: NEW LINKS AND EXPERIMENTAL ADVANCES.NATURAL PRODUCT REPORTS. VOL. 28. ISSUE 7. P. 1311 -1333 233 75% 116
4 BALTZ, RH , (2016) GENETIC MANIPULATION OF SECONDARY METABOLITE BIOSYNTHESIS FOR IMPROVED PRODUCTION IN STREPTOMYCES AND OTHER ACTINOMYCETES.JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY. VOL. 43. ISSUE 2-3. P. 343 -370 157 75% 7
5 WEISSMAN, KJ , (2016) GENETIC ENGINEERING OF MODULAR PKSS: FROM COMBINATORIAL BIOSYNTHESIS TO SYNTHETIC BIOLOGY.NATURAL PRODUCT REPORTS. VOL. 33. ISSUE 2. P. 203 -230 152 82% 4
6 OZCENGIZ, G , DEMAIN, AL , (2013) RECENT ADVANCES IN THE BIOSYNTHESIS OF PENICILLINS, CEPHALOSPORINS AND CLAVAMS AND ITS REGULATION.BIOTECHNOLOGY ADVANCES. VOL. 31. ISSUE 2. P. 287 -311 161 86% 27
7 HERTWECK, C , (2009) THE BIOSYNTHETIC LOGIC OF POLYKETIDE DIVERSITY.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. VOL. 48. ISSUE 26. P. 4688-4716 154 62% 359
8 MCCORMICK, JR , FLARDH, K , (2012) SIGNALS AND REGULATORS THAT GOVERN STREPTOMYCES DEVELOPMENT.FEMS MICROBIOLOGY REVIEWS. VOL. 36. ISSUE 1. P. 206 -231 157 77% 65
9 STAUNTON, J , WEISSMAN, KJ , (2001) POLYKETIDE BIOSYNTHESIS: A MILLENNIUM REVIEW.NATURAL PRODUCT REPORTS. VOL. 18. ISSUE 4. P. 380 -416 137 71% 831
10 FISCHBACH, MA , WALSH, CT , (2006) ASSEMBLY-LINE ENZYMOLOGY FOR POLYKETIDE AND NONRIBOSOMAL PEPTIDE ANTIBIOTICS: LOGIC, MACHINERY, AND MECHANISMS.CHEMICAL REVIEWS. VOL. 106. ISSUE 8. P. 3468-3496 121 68% 569

Classes with closest relation at Level 2


Rank Class id link
1 2890 ACTINOMYCETES//STREPTOMYCES//MARINE ACTINOMYCETES
2 3120 GALACTOSEMIA//GALACTOSE 1 PHOSPHATE URIDYLTRANSFERASE//GALACTOSAEMIA
3 3076 PEPTIDE DEFORMYLASE//ENOYL ACP REDUCTASE//ACYL CARRIER PROTEIN
4 1803 LANTIBIOTIC//OXAZOLE//DOLASTATIN 10
5 3754 SALINOMYCIN//LASALOCID ESTER//MONENSIN A
6 2350 BACILLUS SUBTILIS//SPORULATION//JOURNAL OF BACTERIOLOGY
7 2527 AMINOGLYCOSIDES//AMINOGLYCOSIDE ANTIBIOTICS//2 DEOXYSTREPTAMINE
8 2252 ANGUCYCLINE//IDARUBICIN//ANGUCYCLINONE
9 1066 FUNGAL GENETICS AND BIOLOGY//HYDROPHOBIN//NEUROSPORA
10 3021 SHIKIMATE PATHWAY//CHORISMATE MUTASE//ANTHRANILATE SYNTHASE

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