Class information for:
Level 1: TMEM16A//CALCIUM ACTIVATED CHLORIDE CHANNEL//ANOCTAMIN 1

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
15129 730 44.0 89%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
222 3       MYOTONIC DYSTROPHY//ALDOSTERONE//PHYSIOLOGY 49798
2003 2             MYOTONIC DYSTROPHY//MYOTONIA//MYOTONIC DYSTROPHY TYPE 1 5494
15129 1                   TMEM16A//CALCIUM ACTIVATED CHLORIDE CHANNEL//ANOCTAMIN 1 730

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 TMEM16A authKW 1695255 8% 70% 58
2 CALCIUM ACTIVATED CHLORIDE CHANNEL authKW 1572091 8% 62% 61
3 ANOCTAMIN 1 authKW 687942 3% 66% 25
4 ANOCTAMIN authKW 643497 3% 77% 20
5 TMEM16F authKW 575625 2% 81% 17
6 CA2 ACTIVATED CL CHANNELS authKW 553571 4% 44% 30
7 ANO1 authKW 526812 3% 55% 23
8 TMEM16 authKW 463323 2% 92% 12
9 CALCIUM ACTIVATED CHLORIDE CURRENT authKW 366258 2% 49% 18
10 ANO6 authKW 334623 1% 100% 8

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Physiology 6482 33% 0% 238
2 Cell Biology 910 19% 0% 142
3 Biochemistry & Molecular Biology 399 23% 0% 167
4 Neurosciences 288 14% 0% 101
5 Pharmacology & Pharmacy 211 12% 0% 90
6 Biophysics 137 6% 0% 44
7 Peripheral Vascular Diseases 80 4% 0% 28
8 Respiratory System 78 3% 0% 24
9 Cardiac & Cardiovascular System 57 5% 0% 35
10 Oncology 49 6% 0% 47

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BASIC MED SCI PHARMACOL CLIN PHARMACOL 174281 1% 83% 5
2 CANC BIOL S 172076 2% 34% 12
3 OL TORY TRANSDUCT 83656 0% 100% 2
4 ANAESTHIOL PHARMACOL THER EUT 41828 0% 100% 1
5 ANQING CITY HOSP 41828 0% 100% 1
6 CAM GENOM OURCE 41828 0% 100% 1
7 CARDIOVASC PHEN MOL MED 41828 0% 100% 1
8 CELL BIOCHEM THROMBOSIS HAEMOSTASIS BIOCHE 41828 0% 100% 1
9 CERICOGNATHOSTOMATOL 41828 0% 100% 1
10 CLIN PHARM S 41828 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY 10253 6% 1% 45
2 JOURNAL OF PHYSIOLOGY-LONDON 6374 7% 0% 53
3 CURRENT TOPICS IN MEMBRANES 3853 1% 1% 7
4 JOURNAL OF GENERAL PHYSIOLOGY 3628 2% 1% 17
5 BRITISH JOURNAL OF PHARMACOLOGY 3016 5% 0% 36
6 CHANNELS 1990 1% 1% 5
7 AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 1659 2% 0% 17
8 AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY 734 2% 0% 15
9 CELL CALCIUM 705 1% 0% 7
10 HISTOCHEMISTRY AND CELL BIOLOGY 564 1% 0% 6

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 TMEM16A 1695255 8% 70% 58 Search TMEM16A Search TMEM16A
2 CALCIUM ACTIVATED CHLORIDE CHANNEL 1572091 8% 62% 61 Search CALCIUM+ACTIVATED+CHLORIDE+CHANNEL Search CALCIUM+ACTIVATED+CHLORIDE+CHANNEL
3 ANOCTAMIN 1 687942 3% 66% 25 Search ANOCTAMIN+1 Search ANOCTAMIN+1
4 ANOCTAMIN 643497 3% 77% 20 Search ANOCTAMIN Search ANOCTAMIN
5 TMEM16F 575625 2% 81% 17 Search TMEM16F Search TMEM16F
6 CA2 ACTIVATED CL CHANNELS 553571 4% 44% 30 Search CA2+ACTIVATED+CL+CHANNELS Search CA2+ACTIVATED+CL+CHANNELS
7 ANO1 526812 3% 55% 23 Search ANO1 Search ANO1
8 TMEM16 463323 2% 92% 12 Search TMEM16 Search TMEM16
9 CALCIUM ACTIVATED CHLORIDE CURRENT 366258 2% 49% 18 Search CALCIUM+ACTIVATED+CHLORIDE+CURRENT Search CALCIUM+ACTIVATED+CHLORIDE+CURRENT
10 ANO6 334623 1% 100% 8 Search ANO6 Search ANO6

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 PEDEMONTE, N , GALIETTA, LJV , (2014) STRUCTURE AND FUNCTION OF TMEM16 PROTEINS (ANOCTAMINS).PHYSIOLOGICAL REVIEWS. VOL. 94. ISSUE 2. P. 419 -459 123 48% 74
2 CABRITA, I , WANITCHAKOOL, P , OUSINGSAWAT, J , SIRIANANT, L , BENEDETTO, R , SCHREIBER, R , KUNZELMANN, K , (2016) MODULATING CA2+ SIGNALS: A COMMON THEME FOR TMEM16, IST2, AND TMC.PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY. VOL. 468. ISSUE 3. P. 475 -490 108 62% 2
3 OH, U , JUNG, J , (2016) CELLULAR FUNCTIONS OF TMEM16/ANOCTAMIN.PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY. VOL. 468. ISSUE 3. P. 443 -453 79 70% 5
4 LEBLANC, N , FORREST, AS , AYON, RJ , WIWCHAR, M , ANGERMANN, JE , PRITCHARD, HAT , SINGER, CA , VALENCIK, ML , BRITTON, F , GREENWOOD, IA , (2015) MOLECULAR AND FUNCTIONAL SIGNIFICANCE OF CA2+-ACTIVATED CL- CHANNELS IN PULMONARY ARTERIAL SMOOTH MUSCLE.PULMONARY CIRCULATION. VOL. 5. ISSUE 2. P. 244 -268 128 48% 4
5 MA, K , WANG, H , YU, JK , WEI, MJ , XIAO, QH , (2017) NEW INSIGHTS ON THE REGULATION OF CA2+-ACTIVATED CHLORIDE CHANNEL TMEM16A.JOURNAL OF CELLULAR PHYSIOLOGY. VOL. 232. ISSUE 4. P. 707 -716 68 79% 0
6 HUANG, F , WONG, XM , JAN, LY , (2012) INTERNATIONAL UNION OF BASIC AND CLINICAL PHARMACOLOGY. LXXXV: CALCIUM-ACTIVATED CHLORIDE CHANNELS.PHARMACOLOGICAL REVIEWS. VOL. 64. ISSUE 1. P. 1 -15 77 55% 69
7 PICOLLO, A , MALVEZZI, M , ACCARDI, A , (2015) TMEM16 PROTEINS: UNKNOWN STRUCTURE AND CONFUSING FUNCTIONS.JOURNAL OF MOLECULAR BIOLOGY. VOL. 427. ISSUE 1. P. 94 -105 44 71% 25
8 JIN, X , SHAH, S , DU, XN , ZHANG, HL , GAMPER, N , (2016) ACTIVATION OF CA2+-ACTIVATED CL- CHANNEL ANO1 BY LOCALIZED CA2+ SIGNALS.JOURNAL OF PHYSIOLOGY-LONDON. VOL. 594. ISSUE 1. P. 19 -30 53 51% 7
9 SUNG, TS , O'DRISCOLL, K , ZHENG, HF , YAPP, NJ , LEBLANC, N , KOH, SD , SANDERS, KM , (2016) INFLUENCE OF INTRACELLULAR CA2+ AND ALTERNATIVE SPLICING ON THE PHARMACOLOGICAL PROFILE OF ANO1 CHANNELS.AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY. VOL. 311. ISSUE 3. P. C437 -C451 43 90% 0
10 DURAN, C , HARTZELL, HC , (2011) PHYSIOLOGICAL ROLES AND DISEASES OF TMEM16/ANOCTAMIN PROTEINS: ARE THEY ALL CHLORIDE CHANNELS?.ACTA PHARMACOLOGICA SINICA. VOL. 32. ISSUE 6. P. 685 -692 53 65% 57

Classes with closest relation at Level 1


Rank Class id link
1 18488 BEST DISEASE//BEST VITELLIFORM MACULAR DYSTROPHY//BEST1
2 6592 NONSELECTIVE CATIONIC CURRENT//CYCLOPIAZONIC ACID//SARCOPLASMIC RETICULUM
3 11107 DENTS DISEASE//CLCN5//CHLORIDE CHANNEL
4 23312 MUSCLE CELL LINE//LARGE CONDUCTANCE CHANNEL//COUNTER ION CHANNEL
5 26242 VASOMOTION//RHYTHMIC CONTRACTIONS//VASOMOTION PATTERNS
6 3052 REGULATORY VOLUME DECREASE//VOLUME REGULATION//CELL VOLUME REGULATION
7 11423 OLFACTORY TRANSDUCTION//OLFACTORY RECEPTOR NEURON//OLFACTORY RECEPTOR CELL
8 6126 AIRWAY SURFACE LIQUID//SUBMUCOSAL GLANDS//CYST FIBROSIS PULM TREATMENT
9 2342 CFTR//CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR//CYSTIC FIBROSIS
10 29134 CLIC1//CHLORIDE INTRACELLULAR CHANNEL 1//CLIC4

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