Class information for:
Level 1: ALPHA HELIX MIMETICS//STAPLED PEPTIDES//PROTEOMIMETICS

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
15710 697 49.6 88%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
5 4 CHEMISTRY, ORGANIC//CHEMISTRY, INORGANIC & NUCLEAR//CHEMISTRY, MULTIDISCIPLINARY 1745167
534 3       PYRIMIDINOPHANES//SOLID PHASE SYNTHESIS//INTERNATIONAL JOURNAL OF PEPTIDE AND PROTEIN RESEARCH 19564
1200 2             PEPTAIBOL//FOLDAMERS//PEPTOIDS 9232
15710 1                   ALPHA HELIX MIMETICS//STAPLED PEPTIDES//PROTEOMIMETICS 697

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ALPHA HELIX MIMETICS authKW 633026 2% 85% 17
2 STAPLED PEPTIDES authKW 503773 3% 50% 23
3 PROTEOMIMETICS authKW 311524 1% 89% 8
4 PROTEIN SURFACE RECOGNITION authKW 295702 1% 75% 9
5 HELIX MIMETICS authKW 268324 1% 88% 7
6 PROGRAM CANC CHEM BIOL address 214260 2% 33% 15
7 DICARBA PEPTIDES authKW 131425 0% 100% 3
8 PEPTIDE STAPLING authKW 98567 0% 75% 3
9 HELIX LOOP HELIX PEPTIDES authKW 87617 0% 100% 2
10 HELIX MIMICS authKW 87617 0% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Chemistry, Multidisciplinary 2979 43% 0% 297
2 Chemistry, Organic 2597 28% 0% 197
3 Chemistry, Medicinal 2077 17% 0% 116
4 Biochemistry & Molecular Biology 417 24% 0% 165
5 Biophysics 70 5% 0% 33
6 Biochemical Research Methods 10 2% 0% 16
7 Pharmacology & Pharmacy 1 4% 0% 25
8 Chemistry, Applied 0 1% 0% 7
9 Cell Biology -0 2% 0% 15
10 Chemistry, Analytical -1 1% 0% 9

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PROGRAM CANC CHEM BIOL 214260 2% 33% 15
2 UFR SCI PHARMACEUTUP EA 4258 65710 0% 50% 3
3 ADELAIDE PROSTATE 43808 0% 100% 1
4 ADPE 43808 0% 100% 1
5 ARNA U1212 43808 0% 100% 1
6 ARNA UMR 5320 43808 0% 100% 1
7 BIOMOL LBMCNRSUMR 7203 43808 0% 100% 1
8 CHEM CELL GENOME SCI 43808 0% 100% 1
9 DIPARTIMENTO DISTUDI TECNOL FARMACO 43808 0% 100% 1
10 DRUG DISCOVERY PROGRAMMRC DRDIS 43808 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ORGANIC & BIOMOLECULAR CHEMISTRY 5964 6% 0% 40
2 CHEMBIOCHEM 5182 3% 1% 23
3 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 4131 13% 0% 94
4 ACS CHEMICAL BIOLOGY 3973 2% 1% 14
5 ACS COMBINATORIAL SCIENCE 2861 1% 1% 6
6 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2663 7% 0% 49
7 FUTURE MEDICINAL CHEMISTRY 2340 1% 1% 7
8 CURRENT OPINION IN CHEMICAL BIOLOGY 1873 1% 0% 9
9 ORGANIC LETTERS 1837 5% 0% 33
10 CHEMICAL COMMUNICATIONS 1594 6% 0% 40

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 ALPHA HELIX MIMETICS 633026 2% 85% 17 Search ALPHA+HELIX+MIMETICS Search ALPHA+HELIX+MIMETICS
2 STAPLED PEPTIDES 503773 3% 50% 23 Search STAPLED+PEPTIDES Search STAPLED+PEPTIDES
3 PROTEOMIMETICS 311524 1% 89% 8 Search PROTEOMIMETICS Search PROTEOMIMETICS
4 PROTEIN SURFACE RECOGNITION 295702 1% 75% 9 Search PROTEIN+SURFACE+RECOGNITION Search PROTEIN+SURFACE+RECOGNITION
5 HELIX MIMETICS 268324 1% 88% 7 Search HELIX+MIMETICS Search HELIX+MIMETICS
6 DICARBA PEPTIDES 131425 0% 100% 3 Search DICARBA+PEPTIDES Search DICARBA+PEPTIDES
7 PEPTIDE STAPLING 98567 0% 75% 3 Search PEPTIDE+STAPLING Search PEPTIDE+STAPLING
8 HELIX LOOP HELIX PEPTIDES 87617 0% 100% 2 Search HELIX+LOOP+HELIX+PEPTIDES Search HELIX+LOOP+HELIX+PEPTIDES
9 HELIX MIMICS 87617 0% 100% 2 Search HELIX+MIMICS Search HELIX+MIMICS
10 HYDROGEN BOND SURROGATE 87617 0% 100% 2 Search HYDROGEN+BOND+SURROGATE Search HYDROGEN+BOND+SURROGATE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 AZZARITO, V , LONG, K , MURPHY, NS , WILSON, AJ , (2013) INHIBITION OF ALPHA-HELIX-MEDIATED PROTEIN-PROTEIN INTERACTIONS USING DESIGNED MOLECULES.NATURE CHEMISTRY. VOL. 5. ISSUE 3. P. 161-173 67 51% 234
2 PELAY-GIMENO, M , GLAS, A , KOCH, O , GROSSMANN, TN , (2015) STRUCTURE-BASED DESIGN OF INHIBITORS OF PROTEIN-PROTEIN INTERACTIONS: MIMICKING PEPTIDE BINDING EPITOPES.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. VOL. 54. ISSUE 31. P. 8896 -8927 122 28% 44
3 LAU, YH , DE ANDRADE, P , WU, YT , SPRING, DR , (2015) PEPTIDE STAPLING TECHNIQUES BASED ON DIFFERENT MACROCYCLISATION CHEMISTRIES.CHEMICAL SOCIETY REVIEWS. VOL. 44. ISSUE 1. P. 91 -102 31 70% 46
4 JAYATUNGA, MKP , THOMPSON, S , HAMILTON, AD , (2014) ALPHA-HELIX MIMETICS: OUTWARDS AND UPWARDS.BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. VOL. 24. ISSUE 3. P. 717-724 55 53% 32
5 DEWAL, MB , FIRESTINE, SM , (2011) NON-PEPTIDIC ALPHA-HELICAL MIMETICS AS PROTEIN-PROTEIN INTERACTION INHIBITORS.CURRENT MEDICINAL CHEMISTRY. VOL. 18. ISSUE 16. P. 2420-2428 49 69% 11
6 CROMM, PM , SPIEGEL, J , GROSSMANN, TN , (2015) HYDROCARBON STAPLED PEPTIDES AS MODULATORS OF BIOLOGICAL FUNCTION.ACS CHEMICAL BIOLOGY. VOL. 10. ISSUE 6. P. 1362 -1375 56 39% 29
7 LANNING, M , FLETCHER, S , (2013) RECAPITULATING THE ALPHA-HELIX: NONPEPTIDIC, LOW-MOLECULAR-WEIGHT LIGANDS FOR THE MODULATION OF HELIX-MEDIATED PROTEIN-PROTEIN INTERACTIONS.FUTURE MEDICINAL CHEMISTRY. VOL. 5. ISSUE 18. P. 2157-2174 49 64% 4
8 MOON, H , LIM, HS , (2015) SYNTHESIS AND SCREENING OF SMALL-MOLECULE ALPHA-HELIX MIMETIC LIBRARIES TARGETING PROTEIN-PROTEIN INTERACTIONS.CURRENT OPINION IN CHEMICAL BIOLOGY. VOL. 24. ISSUE . P. 38 -47 40 62% 13
9 LEE, JH , OH, M , KIM, HS , LEE, H , IM, W , LIM, HS , (2016) CONVERTING ONE-FACE ALPHA-HELIX MIMETICS INTO AMPHIPHILIC ALPHA-HELIX MIMETICS AS POTENT INHIBITORS OF PROTEIN-PROTEIN INTERACTIONS.ACS COMBINATORIAL SCIENCE. VOL. 18. ISSUE 1. P. 36 -42 31 84% 1
10 TIAN, Y , LI, JX , ZHAO, H , ZENG, XZ , WANG, DY , LIU, QS , NIU, XG , HUANG, XH , XU, NH , LI, ZG , (2016) STAPLING OF UNPROTECTED HELICAL PEPTIDES VIA PHOTOINDUCED INTRAMOLECULAR THIOL-YNE HYDROTHIOLATION.CHEMICAL SCIENCE. VOL. 7. ISSUE 5. P. 3325 -3330 35 69% 1

Classes with closest relation at Level 1


Rank Class id link
1 26277 CYCLIC BRANCHED PEPTIDES//D ALA D ALA OH//SERINE PROTEASE MODELS
2 21452 SANSALVAMIDE A//BACKBONE CYCLIZATION//BACKBONE CYCLIC PEPTIDES
3 27495 UM SYLVESTER BRAMAN FAMILY BREAST CANC//GCN4P//DNA PROMOTER ELEMENTS TRE AND CRE
4 12385 BETA TURN MIMETIC//PEPTIDOMIMETICS//BICYCLIC DIPEPTIDE
5 6361 BETA PEPTIDES//BETA AMINO ACIDS//FOLDAMERS
6 7436 ALPHA HELIX//ALPHA HELIX STABILITY//N CAP
7 12893 FOLDAMERS//AROMATIC AMIDE//EUROPEEN CHIM BIOL
8 11825 FRAGMENT SCREENING//FRAGMENT BASED DRUG DISCOVERY//NMR SCREENING
9 18612 PEPTOIDS//LACTOSOME//PROTEIN MIMETIC MATERIALS
10 1860 MDM2//MDMX//MDM4

Go to start page