Class information for:
Level 1: INSULIN RECEPTOR//LEPRECHAUNISM//DONOHUE SYNDROME

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
1594 2574 38.1 73%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
176 3       DIABETES CARE//ENDOCRINOLOGY & METABOLISM//TYPE 2 DIABETES 58057
1552 2             INSULIN RECEPTOR//INSULIN DEGRADING ENZYME//INOSITOL PHOSPHOGLYCAN 7396
1594 1                   INSULIN RECEPTOR//LEPRECHAUNISM//DONOHUE SYNDROME 2574

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 INSULIN RECEPTOR authKW 433890 9% 17% 219
2 LEPRECHAUNISM authKW 316619 1% 86% 31
3 DONOHUE SYNDROME authKW 154984 1% 93% 14
4 INSULIN RECEPTOR GENE authKW 110561 1% 55% 17
5 HYBRID RECEPTOR authKW 103847 1% 49% 18
6 RABSON MENDENHALL SYNDROME authKW 94889 0% 100% 8
7 INSULIN RECEPTOR ISOFORMS authKW 60039 0% 56% 9
8 TYPE A INSULIN RESISTANCE authKW 47441 0% 67% 6
9 INSULIN RECEPTOR GENE EXPRESSION authKW 42359 0% 71% 5
10 INSULIN RECEPTOR KINASE authKW 42349 0% 36% 10

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Endocrinology & Metabolism 13873 29% 0% 740
2 Biochemistry & Molecular Biology 10232 52% 0% 1347
3 Biophysics 2226 12% 0% 297
4 Cell Biology 958 12% 0% 301
5 Biology 166 3% 0% 77
6 Physiology 102 3% 0% 83
7 Medicine, Research & Experimental 79 3% 0% 85
8 Pediatrics 17 2% 0% 51
9 CYTOLOGY & HISTOLOGY 9 0% 0% 3
10 Genetics & Heredity 1 2% 0% 47

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 RECEPTOR CELL BIOL 32943 0% 56% 5
2 INSULIN 32280 0% 39% 7
3 WM KECK GENOME INFORMAT 23722 0% 100% 2
4 RECEPTOR SYST BIOL 20504 0% 22% 8
5 CELL BIOL POB 7921 15814 0% 67% 2
6 INSULIN INCRETIN BIOL 15814 0% 67% 2
7 MED ST ANTOINE INSERM U402 15814 0% 67% 2
8 ADDENBROOKES HOSP CLIN BIOCHEM 15810 0% 33% 4
9 ABT IMMUNOCHEM D020 11861 0% 100% 1
10 ADDENBROOKES HOSP B289 11861 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 DIABETES 17352 5% 1% 133
2 JOURNAL OF BIOLOGICAL CHEMISTRY 14971 17% 0% 441
3 ENDOCRINOLOGY 8188 5% 1% 132
4 DIABETOLOGIA 5947 3% 1% 65
5 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 4815 7% 0% 169
6 BIOCHEMICAL JOURNAL 4683 4% 0% 109
7 JOURNAL OF RECEPTOR RESEARCH 4564 1% 3% 15
8 JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 2414 3% 0% 71
9 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 1779 1% 0% 35
10 MOLECULAR ENDOCRINOLOGY 1724 1% 1% 29

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 INSULIN RECEPTOR 433890 9% 17% 219 Search INSULIN+RECEPTOR Search INSULIN+RECEPTOR
2 LEPRECHAUNISM 316619 1% 86% 31 Search LEPRECHAUNISM Search LEPRECHAUNISM
3 DONOHUE SYNDROME 154984 1% 93% 14 Search DONOHUE+SYNDROME Search DONOHUE+SYNDROME
4 INSULIN RECEPTOR GENE 110561 1% 55% 17 Search INSULIN+RECEPTOR+GENE Search INSULIN+RECEPTOR+GENE
5 HYBRID RECEPTOR 103847 1% 49% 18 Search HYBRID+RECEPTOR Search HYBRID+RECEPTOR
6 RABSON MENDENHALL SYNDROME 94889 0% 100% 8 Search RABSON+MENDENHALL+SYNDROME Search RABSON+MENDENHALL+SYNDROME
7 INSULIN RECEPTOR ISOFORMS 60039 0% 56% 9 Search INSULIN+RECEPTOR+ISOFORMS Search INSULIN+RECEPTOR+ISOFORMS
8 TYPE A INSULIN RESISTANCE 47441 0% 67% 6 Search TYPE+A+INSULIN+RESISTANCE Search TYPE+A+INSULIN+RESISTANCE
9 INSULIN RECEPTOR GENE EXPRESSION 42359 0% 71% 5 Search INSULIN+RECEPTOR+GENE+EXPRESSION Search INSULIN+RECEPTOR+GENE+EXPRESSION
10 INSULIN RECEPTOR KINASE 42349 0% 36% 10 Search INSULIN+RECEPTOR+KINASE Search INSULIN+RECEPTOR+KINASE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 TAYLOR, SI , CAMA, A , ACCILI, D , BARBETTI, F , QUON, MJ , SIERRA, MD , SUZUKI, Y , KOLLER, E , LEVYTOLEDANO, R , WERTHEIMER, E , ET AL (1992) MUTATIONS IN THE INSULIN-RECEPTOR GENE.ENDOCRINE REVIEWS. VOL. 13. ISSUE 3. P. 566-595 149 91% 184
2 TAVARE, JM , SIDDLE, K , (1993) MUTATIONAL ANALYSIS OF INSULIN-RECEPTOR FUNCTION - CONSENSUS AND CONTROVERSY.BIOCHIMICA ET BIOPHYSICA ACTA. VOL. 1178. ISSUE 1. P. 21 -39 140 84% 82
3 LEE, JS , PILCH, PF , (1994) THE INSULIN-RECEPTOR - STRUCTURE, FUNCTION, AND SIGNALING.AMERICAN JOURNAL OF PHYSIOLOGY. VOL. 266. ISSUE 2. P. C319-C334 140 70% 174
4 KAHN, CR , WHITE, MF , SHOELSON, SE , BACKER, JM , ARAKI, E , CHEATHAM, B , CSERMELY, P , FOLLI, F , GOLDSTEIN, BJ , HUERTAS, P , ET AL (1993) THE INSULIN-RECEPTOR AND ITS SUBSTRATE - MOLECULAR DETERMINANTS OF EARLY EVENTS IN INSULIN ACTION.RECENT PROGRESS IN HORMONE RESEARCH, VOL 48. VOL. 48. ISSUE . P. 291-339 133 71% 78
5 TAYLOR, SI , (1992) LILLY LECTURE - MOLECULAR MECHANISMS OF INSULIN RESISTANCE - LESSONS FROM PATIENTS WITH MUTATIONS IN THE INSULIN-RECEPTOR GENE.DIABETES. VOL. 41. ISSUE 11. P. 1473-1490 91 86% 243
6 CHEATHAM, B , KAHN, CR , (1995) INSULIN ACTION AND THE INSULIN SIGNALING NETWORK.ENDOCRINE REVIEWS. VOL. 16. ISSUE 2. P. 117-142 104 43% 680
7 DE MEYTS, P , WHITTAKER, J , (2002) STRUCTURAL BIOLOGY OF INSULIN AND IGF1 RECEPTORS: IMPLICATIONS FOR DRUG DESIGN.NATURE REVIEWS DRUG DISCOVERY. VOL. 1. ISSUE 10. P. 769-783 77 59% 292
8 MUSSO, C , COCHRAN, E , MORAN, SA , SKARULIS, MC , ORAL, A , TAYLOR, S , GORDEN, P , (2004) CLINICAL COURSE OF GENETIC DISEASES OF THE INSULIN RECEPTOR (TYPE A AND RABSON-MENDENHALL SYNDROMES) - A 30-YEAR PROSPECTIVE.MEDICINE. VOL. 83. ISSUE 4. P. 209-222 64 82% 79
9 WARD, CW , MENTING, JG , LAWRENCE, MC , (2013) THE INSULIN RECEPTOR CHANGES CONFORMATION IN UNFORESEEN WAYS ON LIGAND BINDING: SHARPENING THE PICTURE OF INSULIN RECEPTOR ACTIVATION.BIOESSAYS. VOL. 35. ISSUE 11. P. 945 -954 57 71% 19
10 KROOK, A , ORAHILLY, S , (1996) MUTANT INSULIN RECEPTORS IN SYNDROMES OF INSULIN RESISTANCE.BAILLIERES CLINICAL ENDOCRINOLOGY AND METABOLISM. VOL. 10. ISSUE 1. P. 97 -122 94 68% 49

Classes with closest relation at Level 1


Rank Class id link
1 16270 PLACENTAL INSULIN RECEPTORS//AARHUS KOMMUNE HOSP OBSTET GYNECOL//BLOOD GROUPING TISSUE TYPING
2 9990 INSULIN DEGRADING ENZYME//INSULIN DEGRADATION//IDE
3 9406 INSULIN RECEPTOR SUBSTRATE//INSULIN RECEPTOR SUBSTRATE 1//IRS 1
4 11092 INOSITOL PHOSPHOGLYCAN//D CHIRO INOSITOL//CHIRO INOSITOL
5 24093 CLIN MEDDISCIPLINA MED INTERNA//BRAIN INSULIN//BALANCO HIDRO SALINO NUCL MED CIRURGIA EXPT
6 10931 MONOMERIC INSULIN//INSULIN MUTANT//FAST ACTING INSULIN
7 35419 ROZITES CAPERATA//LIGNIN DERIVATIVE//MED TISSUE CULTURE SECT
8 29870 CHAIR INTERNAL MED DIABETOL//AURON MISHIEL THERAPY//CENTER PUBL HLTH GENOM
9 30687 KANGEN KARYU//DAN GUA FANG//ALDOSE REDUCTASE INHIBITOR ONO 2235
10 5087 EGF RECEPTOR//COMPUTER PROGRAM FOR MACINTOSHTMII//DIMERIZATION ARM

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