Class information for:
Level 1: 5 HYDROXYMETHYLCYTOSINE//DNA METHYLATION//5HMC

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
1631 2562 54.4 93%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
563 3       DNA METHYLATION//EPIGENETICS//METHYLATION 17086
382 2             DNA METHYLATION//EPIGENETICS//METHYLATION 17086
1631 1                   5 HYDROXYMETHYLCYTOSINE//DNA METHYLATION//5HMC 2562

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 5 HYDROXYMETHYLCYTOSINE authKW 1265008 5% 76% 139
2 DNA METHYLATION authKW 435144 23% 6% 594
3 5HMC authKW 335726 1% 78% 36
4 TET1 authKW 271154 1% 71% 32
5 TET PROTEINS authKW 251732 1% 81% 26
6 DNA DEMETHYLATION authKW 240003 2% 32% 63
7 TET authKW 238435 2% 49% 41
8 5 HYDROXYMETHYLCYTOSINE 5HMC authKW 225133 1% 82% 23
9 5 METHYLCYTOSINE authKW 172378 2% 23% 64
10 DNA HYDROXYMETHYLATION authKW 165875 1% 61% 23

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Genetics & Heredity 17401 35% 0% 886
2 Cell Biology 5944 26% 0% 658
3 Biochemistry & Molecular Biology 5617 40% 0% 1032
4 Biotechnology & Applied Microbiology 3409 17% 0% 423
5 Developmental Biology 2071 6% 0% 155
6 Mathematical & Computational Biology 1498 5% 0% 121
7 Cell & Tissue Engineering 1221 2% 0% 54
8 Biochemical Research Methods 718 6% 0% 166
9 Oncology 359 8% 0% 211
10 Reproductive Biology 179 2% 0% 51

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 EPIGENET PROGRAMME 147428 1% 38% 33
2 MAMMALIAN EPIGENET STUDIES 118460 1% 76% 13
3 EPIGENET 68072 3% 8% 68
4 SIGNALING GENE EXP S 54414 1% 35% 13
5 TROPHOBLAST 54242 1% 14% 33
6 BIOPHYS DYNAM 42722 2% 6% 57
7 GRP DNA METABSTATE MOL BIOL 35750 0% 100% 3
8 MAMMALIAN DEV GRP 35750 0% 100% 3
9 SHANDONG UNIV CUHK SDU JOINT REPROD GENET 35750 0% 100% 3
10 GENET COMPUTAT GENET 34340 0% 41% 7

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 EPIGENOMICS 59343 2% 10% 48
2 EPIGENETICS & CHROMATIN 34626 1% 10% 29
3 GENOME RESEARCH 16706 2% 3% 44
4 EPIGENETICS 15049 1% 7% 18
5 CIBA FOUNDATION SYMPOSIA 13655 2% 2% 56
6 GENOME BIOLOGY 12894 2% 2% 57
7 BRIEFINGS IN FUNCTIONAL GENOMICS 8565 1% 5% 15
8 CELL REPORTS 6687 2% 1% 43
9 CLINICAL EPIGENETICS 5726 1% 3% 14
10 CELL STEM CELL 5696 1% 2% 22

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 5 HYDROXYMETHYLCYTOSINE 1265008 5% 76% 139 Search 5+HYDROXYMETHYLCYTOSINE Search 5+HYDROXYMETHYLCYTOSINE
2 DNA METHYLATION 435144 23% 6% 594 Search DNA+METHYLATION Search DNA+METHYLATION
3 5HMC 335726 1% 78% 36 Search 5HMC Search 5HMC
4 TET1 271154 1% 71% 32 Search TET1 Search TET1
5 TET PROTEINS 251732 1% 81% 26 Search TET+PROTEINS Search TET+PROTEINS
6 DNA DEMETHYLATION 240003 2% 32% 63 Search DNA+DEMETHYLATION Search DNA+DEMETHYLATION
7 TET 238435 2% 49% 41 Search TET Search TET
8 5 HYDROXYMETHYLCYTOSINE 5HMC 225133 1% 82% 23 Search 5+HYDROXYMETHYLCYTOSINE+5HMC Search 5+HYDROXYMETHYLCYTOSINE+5HMC
9 5 METHYLCYTOSINE 172378 2% 23% 64 Search 5+METHYLCYTOSINE Search 5+METHYLCYTOSINE
10 DNA HYDROXYMETHYLATION 165875 1% 61% 23 Search DNA+HYDROXYMETHYLATION Search DNA+HYDROXYMETHYLATION

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 WU, H , ZHANG, Y , (2014) REVERSING DNA METHYLATION: MECHANISMS, GENOMICS, AND BIOLOGICAL FUNCTIONS.CELL. VOL. 156. ISSUE 1-2. P. 45-68 161 77% 228
2 RASMUSSEN, KD , HELIN, K , (2016) ROLE OF TET ENZYMES IN DNA METHYLATION, DEVELOPMENT, AND CANCER.GENES & DEVELOPMENT. VOL. 30. ISSUE 7. P. 733 -750 109 72% 20
3 PASTOR, WA , ARAVIND, L , RAO, A , (2013) TETONIC SHIFT: BIOLOGICAL ROLES OF TET PROTEINS IN DNA DEMETHYLATION AND TRANSCRIPTION.NATURE REVIEWS MOLECULAR CELL BIOLOGY. VOL. 14. ISSUE 6. P. 341 -356 121 68% 213
4 SCHUBELER, D , (2015) FUNCTION AND INFORMATION CONTENT OF DNA METHYLATION.NATURE. VOL. 517. ISSUE 7534. P. 321 -326 75 65% 197
5 SMITH, ZD , MEISSNER, A , (2013) DNA METHYLATION: ROLES IN MAMMALIAN DEVELOPMENT.NATURE REVIEWS GENETICS. VOL. 14. ISSUE 3. P. 204 -220 100 51% 500
6 SHEN, L , SONG, CX , HE, C , ZHANG, Y , (2014) MECHANISM AND FUNCTION OF OXIDATIVE REVERSAL OF DNA AND RNA METHYLATION.ANNUAL REVIEW OF BIOCHEMISTRY, VOL 83. VOL. 83. ISSUE . P. 585 -+ 124 72% 62
7 KOHLI, RM , ZHANG, Y , (2013) TET ENZYMES, TDG AND THE DYNAMICS OF DNA DEMETHYLATION.NATURE. VOL. 502. ISSUE 7472. P. 472-479 78 79% 283
8 SCHUERMANN, D , SCHAR, P , WEBER, AR , (2016) ACTIVE DNA DEMETHYLATION BY DNA REPAIR: FACTS AND UNCERTAINTIES.DNA REPAIR. VOL. 44. ISSUE . P. 92 -102 118 82% 2
9 GUIBERT, S , WEBER, M , (2013) FUNCTIONS OF DNA METHYLATION AND HYDROXYMETHYLATION IN MAMMALIAN DEVELOPMENT.EPIGENETICS AND DEVELOPMENT. VOL. 104. ISSUE . P. 47 -83 142 71% 22
10 CADET, J , WAGNER, JR , (2014) TET ENZYMATIC OXIDATION OF 5-METHYLCYTOSINE, 5-HYDROXYMETHYLCYTOSINE AND 5-FORMYLCYTOSINE.MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS. VOL. 764. ISSUE . P. 18-35 137 65% 14

Classes with closest relation at Level 1


Rank Class id link
1 28689 UHRF1//ICBP90//UHRF2
2 5219 DNA METHYLATION//EWAS//EPIGENOME WIDE ASSOCIATION STUDY
3 10356 METHYLTRANSFERASE ACTIVITY//DNA METHYLATION//METHYL BINDING DOMAIN PROTEIN
4 22078 ICF SYNDROME//EXCELLENCE MOL GENET CANC HUMAN DIS//COBRALINE 1
5 5355 DECITABINE//5 AZA 2 DEOXYCYTIDINE//ZEBULARINE
6 6500 EPIGENETICS//DNA METHYLATION//HISTONE ACETYLATION
7 4702 CHIP SEQ//ENHANCER//PEAK CALLING
8 18199 TRANSGENERATIONAL//METASTABLE EPIALLELE//TRANSGENERATIONAL INHERITANCE
9 16988 DNMT2//ALKB//N 6 METHYLADENOSINE
10 4391 DE NOVO METHYLATION//MYF 3//DNA METHYLATION

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