Class information for:
Level 1: MTAP//METHYLTHIOADENOSINE PHOSPHORYLASE//METHIONINE SALVAGE PATHWAY

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
22214 390 32.9 62%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
236 3       ADENOSINE//NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS//ADENOSINE RECEPTORS 48331
3291 2             PURINE NUCLEOSIDE PHOSPHORYLASE//CARBOHYDRATE CHEM TEAM//METHIONINE DEPENDENCE 1872
22214 1                   MTAP//METHYLTHIOADENOSINE PHOSPHORYLASE//METHIONINE SALVAGE PATHWAY 390

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MTAP authKW 691141 4% 55% 16
2 METHYLTHIOADENOSINE PHOSPHORYLASE authKW 626352 3% 67% 12
3 METHIONINE SALVAGE PATHWAY authKW 563714 3% 60% 12
4 ALPHA KETOGLUTARAMATE authKW 501085 2% 80% 8
5 OMEGA AMIDASE authKW 455530 2% 73% 8
6 METHYLTHIOADENOSINE authKW 396361 2% 56% 9
7 L ALANOSINE authKW 326227 1% 83% 5
8 HINEKA authKW 313180 1% 100% 4
9 1 2 DIHYDROXY 5 METHYLSULFINYLPENTAN 3 ONE authKW 234885 1% 100% 3
10 5 METHYLTHIOADENOSINE NUCLEOSIDASE authKW 234885 1% 100% 3

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Biochemistry & Molecular Biology 756 38% 0% 149
2 Oncology 689 23% 0% 90
3 Biophysics 426 13% 0% 50
4 Biochemical Research Methods 139 7% 0% 28
5 Plant Sciences 64 7% 0% 28
6 Genetics & Heredity 62 7% 0% 26
7 Pharmacology & Pharmacy 35 8% 0% 32
8 Cell Biology 35 7% 0% 27
9 Hematology 26 3% 0% 13
10 Microbiology 25 5% 0% 19

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CHANG GUNG MEM HOSP GASTROENTEROL 78295 0% 100% 1
2 CHANG GUNG MEM HOSP ONCOL 78295 0% 100% 1
3 CLIN 10666 N TORREY PINES RD 78295 0% 100% 1
4 EXPLORATORY PROJECTON CANC STEM CELLS 78295 0% 100% 1
5 F CEDRANGOLO MED CHIRURG 78295 0% 100% 1
6 GUAGNDONG PROV MINIST EDUC 78295 0% 100% 1
7 ISB SIB 78295 0% 100% 1
8 KEY CO FUNCT PROTEOM TRANSCRIPTOM RELATED MA 78295 0% 100% 1
9 MED 92093 78295 0% 100% 1
10 MIDWEST CANC GRP 78295 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOCHEMICAL PHARMACOLOGY 1203 4% 0% 17
2 ADVANCES IN POLYAMINE RESEARCH 1101 0% 1% 1
3 NUCLEOSIDES & NUCLEOTIDES 1054 1% 0% 3
4 GENES CHROMOSOMES & CANCER 880 2% 0% 6
5 JOURNAL OF SUPRAMOLECULAR STRUCTURE AND CELLULAR BIOCHEMISTRY 805 0% 1% 1
6 PHYSIOLOGICAL PLANT PATHOLOGY 695 1% 0% 2
7 ADVANCES IN ENZYMOLOGY AND RELATED AREAS OF MOLECULAR BIOLOGY 596 0% 1% 1
8 BULLETIN OF MOLECULAR BIOLOGY AND MEDICINE 578 0% 1% 1
9 CANCER TREATMENT REPORTS 561 1% 0% 4
10 CANCER RESEARCH 491 4% 0% 16

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 MTAP 691141 4% 55% 16 Search MTAP Search MTAP
2 METHYLTHIOADENOSINE PHOSPHORYLASE 626352 3% 67% 12 Search METHYLTHIOADENOSINE+PHOSPHORYLASE Search METHYLTHIOADENOSINE+PHOSPHORYLASE
3 METHIONINE SALVAGE PATHWAY 563714 3% 60% 12 Search METHIONINE+SALVAGE+PATHWAY Search METHIONINE+SALVAGE+PATHWAY
4 ALPHA KETOGLUTARAMATE 501085 2% 80% 8 Search ALPHA+KETOGLUTARAMATE Search ALPHA+KETOGLUTARAMATE
5 OMEGA AMIDASE 455530 2% 73% 8 Search OMEGA+AMIDASE Search OMEGA+AMIDASE
6 METHYLTHIOADENOSINE 396361 2% 56% 9 Search METHYLTHIOADENOSINE Search METHYLTHIOADENOSINE
7 L ALANOSINE 326227 1% 83% 5 Search L+ALANOSINE Search L+ALANOSINE
8 HINEKA 313180 1% 100% 4 Search HINEKA Search HINEKA
9 1 2 DIHYDROXY 5 METHYLSULFINYLPENTAN 3 ONE 234885 1% 100% 3 Search 1+2+DIHYDROXY+5+METHYLSULFINYLPENTAN+3+ONE Search 1+2+DIHYDROXY+5+METHYLSULFINYLPENTAN+3+ONE
10 5 METHYLTHIOADENOSINE NUCLEOSIDASE 234885 1% 100% 3 Search 5+METHYLTHIOADENOSINE+NUCLEOSIDASE Search 5+METHYLTHIOADENOSINE+NUCLEOSIDASE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 BERTINO, JR , WAUD, WR , PARKER, WB , LUBIN, M , (2011) TARGETING TUMORS THAT LACK METHYLTHIOADENOSINE PHOSPHORYLASE (MTAP) ACTIVITY CURRENT STRATEGIES.CANCER BIOLOGY & THERAPY. VOL. 11. ISSUE 7. P. 627-632 37 82% 31
2 ALBERS, E , (2009) METABOLIC CHARACTERISTICS AND IMPORTANCE OF THE UNIVERSAL METHIONINE SALVAGE PATHWAY RECYCLING METHIONINE FROM 5 '-METHYLTHIOADENOSINE.IUBMB LIFE. VOL. 61. ISSUE 12. P. 1132 -1142 51 57% 62
3 HE, HL , LEE, YE , SHIUE, YL , LEE, SW , CHEN, TJ , LI, CF , (2015) CHARACTERIZATION AND PROGNOSTIC SIGNIFICANCE OF METHYLTHIOADENOSINE PHOSPHORYLASE DEFICIENCY IN NASOPHARYNGEAL CARCINOMA.MEDICINE. VOL. 94. ISSUE 49. P. - 33 69% 0
4 TANG, BQ , KADARIYA, Y , CHEN, YB , SLIFKER, M , KRUGER, WD , (2015) EXPRESSION OF MTAP INHIBITS TUMOR-RELATED PHENOTYPES IN HT1080 CELLS VIA A MECHANISM UNRELATED TO ITS ENZYMATIC FUNCTION.G3-GENES GENOMES GENETICS. VOL. 5. ISSUE 1. P. 35 -44 26 68% 2
5 KINDLER, H , BURRIS, H , SANDLER, A , OLIFF, I , (2009) A PHASE II MULTICENTER STUDY OF L-ALANOSINE, A POTENT INHIBITOR OF ADENINE BIOSYNTHESIS, IN PATIENTS WITH MTAP-DEFICIENT CANCER.INVESTIGATIONAL NEW DRUGS. VOL. 27. ISSUE 1. P. 75 -81 22 88% 25
6 DE OLIVEIRA, SFV , GANZINELLI, M , CHILA, R , SERINO, L , MACIEL, ME , URBAN, CD , DE LIMA, RS , CAVALLI, IJ , GENERALI, D , BROGGINI, M , ET AL (2016) CHARACTERIZATION OF MTAP GENE EXPRESSION IN BREAST CANCER PATIENTS AND CELL LINES.PLOS ONE. VOL. 11. ISSUE 1. P. - 21 75% 0
7 CONDE, L , VILASECA, I , ALOS, L , BERNAL-SPREKELSEN, M , CARDESA, A , NADAL, A , (2012) METHYLTHIOADENOSINE PHOSPHORYLASE INACTIVATION DEPENDS ON GENE DELETION IN LARYNGEAL SQUAMOUS CELL CARCINOMA.HISTOPATHOLOGY. VOL. 61. ISSUE 6. P. 1082-1088 20 71% 1
8 SU, CY , CHANG, YC , CHAN, YC , LIN, TC , HUANG, MS , YANG, CJ , HSIAO, M , (2014) MTAP IS AN INDEPENDENT PROGNOSIS MARKER AND THE CONCORDANT LOSS OF MTAP AND P16 EXPRESSION PREDICTS SHORT SURVIVAL IN NON-SMALL CELL LUNG CANCER PATIENTS.EJSO. VOL. 40. ISSUE 9. P. 1143 -1150 19 68% 5
9 MIYAZAKI, S , NISHIOKA, J , SHIRAISH, T , MATSUMINE, A , UCHIDA, A , NOBORI, T , (2007) METHYLTHIOADENOSINE PHOSPHORYLASE DEFICIENCY IN JAPANESE OSTEOSARCOMA PATIENTS.INTERNATIONAL JOURNAL OF ONCOLOGY. VOL. 31. ISSUE 5. P. 1069-1076 21 70% 7
10 KADARIYA, Y , YIN, B , TANG, BQ , SHINTON, SA , QUINLIVAN, EP , HUA, X , KLEIN-SZANTO, A , AL-SALEEM, TI , BASSING, CH , HARDY, RR , ET AL (2009) MICE HETEROZYGOUS FOR GERM-LINE MUTATIONS IN METHYLTHIOADENOSINE PHOSPHORYLASE (MTAP) DIE PREMATURELY OF T-CELL LYMPHOMA.CANCER RESEARCH. VOL. 69. ISSUE 14. P. 5961-5969 19 68% 20

Classes with closest relation at Level 1


Rank Class id link
1 22761 METHIONINE DEPENDENCE//METHIONINASE//METHIONINE GAMMA LYASE
2 9868 PURINE NUCLEOSIDE PHOSPHORYLASE//CARBOHYDRATE CHEM TEAM//NUCLEOSIDE HYDROLASE
3 24119 QUERCETINASE//TRIPYRRIN//BAI LIGANDS
4 14339 SPERMIDINE SYNTHASE//S ADENOSYLMETHIONINE DECARBOXYLASE//AMINOPROPYLTRANSFERASE
5 32029 APRT DEFICIENCY//ADENINE PHOSPHORIBOSYLTRANSFERASE DEFICIENCY//2 8 DIHYDROXYADENINE
6 11426 S ADENOSYLHOMOCYSTEINE HYDROLASE//S ADENOSYL L HOMOCYSTEINE HYDROLASE//3 DEAZAADENOSINE
7 4549 P16//CDKN2A//P16INK4A
8 37309 ARGYROPELECUS HEMIGYMNUS//BIOL MARINE ECOL//LUMINESCENT FISHES
9 7647 METHIONINE ADENOSYLTRANSFERASE//S ADENOSYLMETHIONINE//GLYCINE N METHYLTRANSFERASE
10 26698 S ADENOSYLHOMOCYSTEINE//W CHINA PRECLIN FORENS MED SCI//BASIC CARDIOCEREBRAL VASC DIS

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