Class information for:
Level 1: ROR GAMMA//ROR ALPHA//RORC

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
23794 334 45.1 91%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
262 3       AUTOPHAGY//RESVERATROL//HISTONE DEACETYLASE INHIBITOR 44558
2654 2             NURR1//NUR77//PGC 1 ALPHA 3465
23794 1                   ROR GAMMA//ROR ALPHA//RORC 334

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ROR GAMMA authKW 1560071 7% 74% 23
2 ROR ALPHA authKW 1119896 8% 44% 28
3 RORC authKW 381232 4% 30% 14
4 RETINOIC ACID RECEPTOR RELATED ORPHAN RECEPTOR authKW 380926 1% 83% 5
5 RETINOID RELATED ORPHAN RECEPTOR GAMMA T authKW 380926 1% 83% 5
6 RORA authKW 304729 3% 33% 10
7 NR1F1 authKW 274268 1% 100% 3
8 RETINOID RELATED ORPHAN RECEPTORS authKW 274268 1% 100% 3
9 TH17 CELL DIFFERENTIATION authKW 253947 1% 56% 5
10 REV ERB BETA authKW 243791 1% 67% 4

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Biochemistry & Molecular Biology 738 40% 0% 135
2 Chemistry, Medicinal 606 13% 0% 44
3 Endocrinology & Metabolism 317 13% 0% 43
4 Cell Biology 260 16% 0% 53
5 Biophysics 87 7% 0% 23
6 Genetics & Heredity 65 7% 0% 24
7 Neurosciences 58 10% 0% 34
8 Immunology 32 7% 0% 22
9 Pharmacology & Pharmacy 32 8% 0% 28
10 Chemistry, Organic 30 6% 0% 20

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 UNITS SPIRE GREEN 7 9 205699 1% 75% 3
2 CHEM MOL THER EUT 117540 1% 43% 3
3 AGING AGE RELATED DIS 91423 0% 100% 1
4 BONE BIOL IMPLANT THER Y DENT 91423 0% 100% 1
5 CARDIOVASC PHYSIOL ZAFES 91423 0% 100% 1
6 CENT TECHNOL BIOMOL PROD UNIT 91423 0% 100% 1
7 CENT TECHNOL PROT STRUCT UNIT 91423 0% 100% 1
8 CNRS FEDERAT RECH NECKER ENFANTS MALADES 91423 0% 100% 1
9 CNRS UMR 7102NPA 91423 0% 100% 1
10 CNRS URA 1199 91423 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MOLECULAR ENDOCRINOLOGY 3172 4% 0% 14
2 ACS MEDICINAL CHEMISTRY LETTERS 2387 2% 0% 6
3 MOLECULAR AUTISM 1397 1% 1% 2
4 ACS CHEMICAL BIOLOGY 1055 1% 0% 5
5 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 797 4% 0% 15
6 JOURNAL OF MOLECULAR ENDOCRINOLOGY 694 1% 0% 4
7 JOURNAL OF NEUROGENETICS 673 1% 0% 2
8 EXPERT OPINION ON THERAPEUTIC PATENTS 651 1% 0% 4
9 CHEMMEDCHEM 632 1% 0% 4
10 DRUG NEWS & PERSPECTIVES 537 1% 0% 2

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 ROR GAMMA 1560071 7% 74% 23 Search ROR+GAMMA Search ROR+GAMMA
2 ROR ALPHA 1119896 8% 44% 28 Search ROR+ALPHA Search ROR+ALPHA
3 RORC 381232 4% 30% 14 Search RORC Search RORC
4 RETINOIC ACID RECEPTOR RELATED ORPHAN RECEPTOR 380926 1% 83% 5 Search RETINOIC+ACID+RECEPTOR+RELATED+ORPHAN+RECEPTOR Search RETINOIC+ACID+RECEPTOR+RELATED+ORPHAN+RECEPTOR
5 RETINOID RELATED ORPHAN RECEPTOR GAMMA T 380926 1% 83% 5 Search RETINOID+RELATED+ORPHAN+RECEPTOR+GAMMA+T Search RETINOID+RELATED+ORPHAN+RECEPTOR+GAMMA+T
6 RORA 304729 3% 33% 10 Search RORA Search RORA
7 NR1F1 274268 1% 100% 3 Search NR1F1 Search NR1F1
8 RETINOID RELATED ORPHAN RECEPTORS 274268 1% 100% 3 Search RETINOID+RELATED+ORPHAN+RECEPTORS Search RETINOID+RELATED+ORPHAN+RECEPTORS
9 TH17 CELL DIFFERENTIATION 253947 1% 56% 5 Search TH17+CELL+DIFFERENTIATION Search TH17+CELL+DIFFERENTIATION
10 REV ERB BETA 243791 1% 67% 4 Search REV+ERB+BETA Search REV+ERB+BETA

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 CYR, P , BRONNER, SM , CRAWFORD, JJ , (2016) RECENT PROGRESS ON NUCLEAR RECEPTOR ROR GAMMA MODULATORS.BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. VOL. 26. ISSUE 18. P. 4387 -4393 38 73% 3
2 FITZSIMMONS, RL , LAU, P , MUSCAT, GEO , (2012) RETINOID-RELATED ORPHAN RECEPTOR ALPHA AND THE REGULATION OF LIPID HOMEOSTASIS.JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. VOL. 130. ISSUE 3-5. P. 159 -168 56 59% 7
3 KAMENECKA, TM , LYDA, B , CHANG, MR , GRIFFIN, PR , (2013) SYNTHETIC MODULATORS OF THE RETINOIC ACID RECEPTOR-RELATED ORPHAN RECEPTORS.MEDCHEMCOMM. VOL. 4. ISSUE 5. P. 764-776 37 73% 13
4 ZHANG, Y , LUO, XY , WU, DH , XU, Y , (2015) ROR NUCLEAR RECEPTORS: STRUCTURES, RELATED DISEASES, AND DRUG DISCOVERY.ACTA PHARMACOLOGICA SINICA. VOL. 36. ISSUE 1. P. 71 -87 44 49% 10
5 FAUBER, BP , GOBBI, A , SAVY, P , BURTON, B , DENG, YZ , EVERETT, C , LA, H , JOHNSON, AR , LOCKEY, P , NORMAN, M , ET AL (2015) IDENTIFICATION OF N-SULFONYL-TETRAHYDROQUINOLINES AS RORC INVERSE AGONISTS.BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. VOL. 25. ISSUE 19. P. 4109 -4113 33 70% 4
6 RUTZ, S , EIDENSCHENK, C , KIEFER, JR , OUYANG, WJ , (2016) POST-TRANSLATIONAL REGULATION OF ROR GAMMA T-A THERAPEUTIC TARGET FOR THE MODULATION OF INTERLEUKIN-17-MEDIATED RESPONSES IN AUTOIMMUNE DISEASES.CYTOKINE & GROWTH FACTOR REVIEWS. VOL. 30. ISSUE . P. 1 -17 61 37% 0
7 KOJETIN, DJ , BURRIS, TP , (2014) REV-ERB AND ROR NUCLEAR RECEPTORS AS DRUG TARGETS.NATURE REVIEWS DRUG DISCOVERY. VOL. 13. ISSUE 3. P. 197 -216 43 32% 66
8 WU, XS , WANG, R , XING, YL , XUE, XQ , ZHANG, Y , LU, YZ , SONG, Y , LUO, XY , WU, C , ZHOU, YL , ET AL (2016) DISCOVERY AND STRUCTURAL OPTIMIZATION OF 4-(4-(BENZYLOXY) PHENYL)-3,4-DIHYDROPYRIMIDIN-2(1H)-ONES AS RORC INVERSE AGONISTS.ACTA PHARMACOLOGICA SINICA. VOL. 37. ISSUE 11. P. 1516 -1524 23 79% 0
9 WANG, YH , YANG, T , LIU, Q , MA, YL , YANG, LQ , ZHOU, L , XIANG, ZJ , CHENG, ZQ , LU, SJ , ORBAND-MILLER, LA , ET AL (2015) DISCOVERY OF N-(4-ARYL-5-ARYLOXY-THIAZOL-2-YL)-AMIDES AS POTENT ROR GAMMA T INVERSE AGONISTS.BIOORGANIC & MEDICINAL CHEMISTRY. VOL. 23. ISSUE 17. P. 5293 -5302 23 77% 3
10 FAUBER, BP , MAGNUSON, S , (2014) MODULATORS OF THE NUCLEAR RECEPTOR RETINOIC ACID RECEPTOR-RELATED ORPHAN RECEPTOR-GAMMA (ROR GAMMA OR RORC).JOURNAL OF MEDICINAL CHEMISTRY. VOL. 57. ISSUE 14. P. 5871 -5892 37 42% 27

Classes with closest relation at Level 1


Rank Class id link
1 9701 LURCHER//PURKINJE CELL//NEUROBIOL PRENTISSAGE
2 20282 TR4//GERM CELL NUCLEAR FACTOR//GEORGE WHIPPLE CANC
3 21178 ESTROGEN RELATED RECEPTOR ALPHA//ESTROGEN RELATED RECEPTOR//ERR GAMMA
4 369 CLOCK GENES//BMAL1//CIRCADIAN CLOCK
5 10090 LIVER X RECEPTOR//LXR//T0901317
6 723 IL 17//INTERLEUKIN 17//TH17
7 12289 NURR1//NUR77//NGFI B
8 5713 RETINOIC ACID RECEPTOR//RXR//RETINOYLATION
9 17169 INNATE LYMPHOID CELLS//GROUP 2 INNATE LYMPHOID CELLS//ILC2
10 2679 THYROID HORMONE RECEPTOR//RESISTANCE TO THYROID HORMONE//V ERBA

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