Class information for:
Level 1: MELANOCORTIN//MELANOCORTIN RECEPTOR//MELANOCORTIN 4 RECEPTOR

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
2515 2221 44.4 85%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
633 3       TYROSINASE//MELANOGENESIS//PIGMENT CELL RESEARCH 12915
2294 2             MELANOCORTIN//MELANOCORTIN RECEPTOR//MELANOCORTIN 4 RECEPTOR 4561
2515 1                   MELANOCORTIN//MELANOCORTIN RECEPTOR//MELANOCORTIN 4 RECEPTOR 2221

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MELANOCORTIN authKW 1672551 12% 47% 258
2 MELANOCORTIN RECEPTOR authKW 1664558 9% 62% 195
3 MELANOCORTIN 4 RECEPTOR authKW 1338044 6% 74% 132
4 MC4R authKW 646310 4% 51% 92
5 SHU9119 authKW 488785 2% 83% 43
6 MTII authKW 437646 2% 86% 37
7 AGRP authKW 408154 3% 42% 70
8 AGOUTI RELATED PROTEIN authKW 392246 2% 52% 55
9 MELANOCORTIN 3 RECEPTOR authKW 334367 1% 81% 30
10 MELANOTROPIN authKW 292031 2% 59% 36

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Endocrinology & Metabolism 19177 36% 0% 800
2 Chemistry, Medicinal 1968 9% 0% 210
3 Biochemistry & Molecular Biology 1636 26% 0% 570
4 Pharmacology & Pharmacy 1211 16% 0% 351
5 Neurosciences 1066 15% 0% 332
6 Nutrition & Dietetics 543 5% 0% 105
7 Physiology 350 5% 0% 118
8 Genetics & Heredity 261 6% 0% 132
9 Cell Biology 195 7% 0% 153
10 Biophysics 178 4% 0% 97

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PHARMACEUT PHARMACOL 97107 1% 24% 29
2 OBES METAB DISORDERS 42955 0% 63% 5
3 ENDOCRINOL DIABET METAB MOL MED 40801 1% 21% 14
4 ANAT PHYSIOL PHARMACOL 39710 2% 8% 38
5 FISH PHYSIOL BIOTECHNOL 37450 1% 21% 13
6 PEDIAT NUTR GASTROENTEROL 34362 0% 50% 5
7 STUDY WEIGHT REGULAT ASSOCIATED DISORDERS 33827 0% 31% 8
8 CHAIR PL PHARMACOL 30929 0% 75% 3
9 MARIN BIOSCI 27493 0% 100% 2
10 METAB ENDOCRINOL DIABETOL NUTR 27493 0% 100% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PEPTIDES 28941 6% 2% 136
2 ENDOCRINOLOGY 4474 4% 0% 91
3 NEUROPEPTIDES 3617 1% 1% 26
4 JOURNAL OF MEDICINAL CHEMISTRY 3035 3% 0% 70
5 INTERNATIONAL JOURNAL OF OBESITY 3024 2% 1% 39
6 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 2959 3% 0% 75
7 JOURNAL OF MOLECULAR ENDOCRINOLOGY 2866 1% 1% 21
8 GENERAL AND COMPARATIVE ENDOCRINOLOGY 2202 2% 0% 36
9 AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY 1993 2% 0% 36
10 JOURNAL OF NEUROENDOCRINOLOGY 1531 1% 1% 19

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 MELANOCORTIN 1672551 12% 47% 258 Search MELANOCORTIN Search MELANOCORTIN
2 MELANOCORTIN RECEPTOR 1664558 9% 62% 195 Search MELANOCORTIN+RECEPTOR Search MELANOCORTIN+RECEPTOR
3 MELANOCORTIN 4 RECEPTOR 1338044 6% 74% 132 Search MELANOCORTIN+4+RECEPTOR Search MELANOCORTIN+4+RECEPTOR
4 MC4R 646310 4% 51% 92 Search MC4R Search MC4R
5 SHU9119 488785 2% 83% 43 Search SHU9119 Search SHU9119
6 MTII 437646 2% 86% 37 Search MTII Search MTII
7 AGRP 408154 3% 42% 70 Search AGRP Search AGRP
8 AGOUTI RELATED PROTEIN 392246 2% 52% 55 Search AGOUTI+RELATED+PROTEIN Search AGOUTI+RELATED+PROTEIN
9 MELANOCORTIN 3 RECEPTOR 334367 1% 81% 30 Search MELANOCORTIN+3+RECEPTOR Search MELANOCORTIN+3+RECEPTOR
10 MELANOTROPIN 292031 2% 59% 36 Search MELANOTROPIN Search MELANOTROPIN

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 TAO, YX , (2010) THE MELANOCORTIN-4 RECEPTOR: PHYSIOLOGY, PHARMACOLOGY, AND PATHOPHYSIOLOGY.ENDOCRINE REVIEWS. VOL. 31. ISSUE 4. P. 506-543 324 71% 143
2 WIKBERG, JES , MUTULIS, F , (2008) TARGETING MELANOCORTIN RECEPTORS: AN APPROACH TO TREAT WEIGHT DISORDERS AND SEXUAL DYSFUNCTION.NATURE REVIEWS DRUG DISCOVERY. VOL. 7. ISSUE 4. P. 307 -323 167 75% 70
3 GIRARDET, C , BUTLER, AA , (2014) NEURAL MELANOCORTIN RECEPTORS IN OBESITY AND RELATED METABOLIC DISORDERS.BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE. VOL. 1842. ISSUE 3. P. 482-494 145 68% 24
4 IRANI, BG , HOLDER, JR , TODOROVIC, A , WILCZYNSKI, AM , JOSEPH, CG , WILSON, KR , HASKELL-LUEVANO, C , (2004) PROGRESS IN THE DEVELOPMENT OF MELANOCORTIN RECEPTOR SELECTIVE LIGANDS.CURRENT PHARMACEUTICAL DESIGN. VOL. 10. ISSUE 28. P. 3443 -3479 199 56% 36
5 HINNEY, A , VOLCKMAR, AL , KNOLL, N , (2013) MELANOCORTIN-4 RECEPTOR IN ENERGY HOMEOSTASIS AND OBESITY PATHOGENESIS.G PROTEIN-COUPLED RECEPTORS IN ENERGY HOMEOSTASIS AND OBESITY PATHOGENSIS. VOL. 114. ISSUE . P. 147-191 108 67% 33
6 KRASHES, MJ , LOWELL, BB , GARFIELD, AS , (2016) MELANOCORTIN-4 RECEPTOR-REGULATED ENERGY HOMEOSTASIS.NATURE NEUROSCIENCE. VOL. 19. ISSUE 2. P. 206 -219 80 60% 9
7 MOUNTJOY, KG , (2010) FUNCTIONS FOR PRO-OPIOMELANOCORTIN-DERIVED PEPTIDES IN OBESITY AND DIABETES.BIOCHEMICAL JOURNAL. VOL. 428. ISSUE . P. 305-324 131 55% 43
8 ADAN, RAH , TIESJEMA, B , HILLEBRAND, JJG , LA FLEUR, SE , KAS, MJH , DE KROM, M , (2006) THE MC4 RECEPTOR AND CONTROL OF APPETITE.BRITISH JOURNAL OF PHARMACOLOGY. VOL. 149. ISSUE 7. P. 815 -827 105 71% 108
9 BEGRICHE, K , GIRARDET, C , MCDONALD, P , BUTLER, AA , (2013) MELANOCORTIN-3 RECEPTORS AND METABOLIC HOMEOSTASIS.G PROTEIN-COUPLED RECEPTORS IN ENERGY HOMEOSTASIS AND OBESITY PATHOGENSIS. VOL. 114. ISSUE . P. 109-146 115 58% 11
10 LAM, DD , FAROOQI, IS , HEISLER, LK , (2007) MELANOCORTIN RECEPTORS AS TARGETS IN THE TREATMENT OF OBESITY.CURRENT TOPICS IN MEDICINAL CHEMISTRY. VOL. 7. ISSUE 11. P. 1098 -1110 119 67% 2

Classes with closest relation at Level 1


Rank Class id link
1 7390 MELANOCORTIN 1 RECEPTOR//ALPHA MELANOCYTE STIMULATING HORMONE//MC1R
2 25883 TRIPLE A SYNDROME//ALLGROVE SYNDROME//ALACRIMA
3 6960 HYPOTHALAM//HYPOTHALAMUS//LEPTIN RESISTANCE
4 31341 ATTRACTIN//ZITTER RAT//SPONTANEOUSLY EPILEPTIC RAT SER
5 15828 MC1R//COAT COLOUR//COAT COLOR
6 35680 LOU C JALL RATS//COMPLEXE SCI CEZEAUX//WASTING DISORDER
7 18470 SEMAX//ORG 2766//ACTH4 9 ANALOG
8 36613 PROLYLCARBOXYPEPTIDASE//PRCP//ANGIOTENSINASE C
9 5522 PROOPIOMELANOCORTIN//BETA ENDORPHIN//PROOPIOCORTIN
10 20544 MELANOMA IMAGING//IMAGERIE MOL THER IE VECTORISEE//ALPHA MELANOCYTE STIMULATING HORMONE HYBRID PEPTIDE

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