Class information for:
Level 1: MOL CELLULAR SIGNALING//TAT BH4//2 EPI 2 O ACETYLTHEVETIN BGHSC 74

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
27975 216 53.6 92%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
328 3       PHOSPHOLIPASE D//STIM1//REGUCALCIN 38118
1764 2             STIM1//ORAI1//STORE OPERATED CALCIUM ENTRY 6417
27975 1                   MOL CELLULAR SIGNALING//TAT BH4//2 EPI 2 O ACETYLTHEVETIN BGHSC 74 216

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MOL CELLULAR SIGNALING address 404997 9% 15% 19
2 TAT BH4 authKW 254459 1% 60% 3
3 2 EPI 2 O ACETYLTHEVETIN BGHSC 74 authKW 141368 0% 100% 1
4 ADV INTEGRAT SPORTS MED address 141368 0% 100% 1
5 AGLYCIA authKW 141368 0% 100% 1
6 APOPTOSIS ENDOPLASMIC RETICULUM authKW 141368 0% 100% 1
7 AXON GROWTH POTENTIAL authKW 141368 0% 100% 1
8 B LYMPHOBLAST CELL LINES authKW 141368 0% 100% 1
9 BASIC THEORY TRADIT CHINESE MED TCA address 141368 0% 100% 1
10 BAX AND APOPTOSIS authKW 141368 0% 100% 1

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Cell Biology 1560 44% 0% 94
2 Biochemistry & Molecular Biology 697 48% 0% 103
3 Biophysics 141 10% 0% 22
4 Oncology 127 14% 0% 31
5 Medicine, Research & Experimental 53 7% 0% 15
6 Genetics & Heredity 26 6% 0% 13
7 Physiology 24 5% 0% 10
8 Film, Radio, Television 17 0% 0% 1
9 Neurosciences 11 7% 0% 15
10 Pharmacology & Pharmacy 9 6% 0% 14

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MOL CELLULAR SIGNALING 404997 9% 15% 19
2 ADV INTEGRAT SPORTS MED 141368 0% 100% 1
3 BASIC THEORY TRADIT CHINESE MED TCA 141368 0% 100% 1
4 CASE COMPREHENS CANC MED 141368 0% 100% 1
5 CASE COMPREHENS CANC UNIV HOSP CASE MED 141368 0% 100% 1
6 CELLULAR MOL PHARMACOL NIH 141368 0% 100% 1
7 CHEM BIOTECHNOL ENGNEERING 141368 0% 100% 1
8 CNRS MDAM 141368 0% 100% 1
9 COGNIT NEUROSCI HUMAN GENET 141368 0% 100% 1
10 COMPUTAT OMICS SYST BIOL GRP 141368 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CELL CALCIUM 7116 6% 0% 12
2 BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH 1523 3% 0% 7
3 ONCOGENE 935 5% 0% 11
4 CELL DEATH AND DIFFERENTIATION 709 2% 0% 4
5 CURRENT CANCER DRUG TARGETS 591 1% 0% 2
6 SIGHT AND SOUND 419 0% 0% 1
7 SCIENCE SIGNALING 363 1% 0% 2
8 CELLULAR ONCOLOGY 298 0% 0% 1
9 JOURNAL OF BIOENERGETICS AND BIOMEMBRANES 293 1% 0% 2
10 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 286 6% 0% 12

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 TAT BH4 254459 1% 60% 3 Search TAT+BH4 Search TAT+BH4
2 2 EPI 2 O ACETYLTHEVETIN BGHSC 74 141368 0% 100% 1 Search 2+EPI+2+O+ACETYLTHEVETIN+BGHSC+74 Search 2+EPI+2+O+ACETYLTHEVETIN+BGHSC+74
3 AGLYCIA 141368 0% 100% 1 Search AGLYCIA Search AGLYCIA
4 APOPTOSIS ENDOPLASMIC RETICULUM 141368 0% 100% 1 Search APOPTOSIS+ENDOPLASMIC+RETICULUM Search APOPTOSIS+ENDOPLASMIC+RETICULUM
5 AXON GROWTH POTENTIAL 141368 0% 100% 1 Search AXON+GROWTH+POTENTIAL Search AXON+GROWTH+POTENTIAL
6 B LYMPHOBLAST CELL LINES 141368 0% 100% 1 Search B+LYMPHOBLAST+CELL+LINES Search B+LYMPHOBLAST+CELL+LINES
7 BAX AND APOPTOSIS 141368 0% 100% 1 Search BAX+AND+APOPTOSIS Search BAX+AND+APOPTOSIS
8 BCL 2 THAPSIGARGIN 141368 0% 100% 1 Search BCL+2+THAPSIGARGIN Search BCL+2+THAPSIGARGIN
9 BH4 BCL 2 141368 0% 100% 1 Search BH4+BCL+2 Search BH4+BCL+2
10 BH4 DOMAIN TARGETS 141368 0% 100% 1 Search BH4+DOMAIN+TARGETS Search BH4+DOMAIN+TARGETS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 DISTELHORST, CW , BOOTMAN, MD , (2011) BCL-2 INTERACTION WITH THE INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR: ROLE IN CA2+ SIGNALING AND DISEASE.CELL CALCIUM. VOL. 50. ISSUE 3. P. 234-241 36 41% 42
2 VERVLIET, T , PARYS, JB , BULTYNCK, G , (2016) BCL-2 PROTEINS AND CALCIUM SIGNALING: COMPLEXITY BENEATH THE SURFACE.ONCOGENE. VOL. 35. ISSUE 39. P. 5079 -5092 55 27% 0
3 RONG, Y , DISTELHORST, CW , (2008) BCL-2 PROTEIN FAMILY MEMBERS: VERSATILE REGULATORS OF CALCIUM SIGNALING IN CELL SURVIVAL AND APOPTOSIS.ANNUAL REVIEW OF PHYSIOLOGY. VOL. 70. ISSUE . P. 73-91 36 35% 178
4 BITTREMIEUX, M , PARYS, JB , PINTON, P , BULTYNCK, G , (2016) ER FUNCTIONS OF ONCOGENES AND TUMOR SUPPRESSORS: MODULATORS OF INTRACELLULAR CA2+ SIGNALING.BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH. VOL. 1863. ISSUE 6. P. 1364 -1378 37 22% 5
5 MONACO, G , BECKERS, M , IVANOVA, H , MISSIAEN, L , PARYS, JB , DE SMEDT, H , BULTYNCK, G , (2012) PROFILING OF THE BCL-2/BCL-X-L-BINDING SITES ON TYPE 1 IP3 RECEPTOR.BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. VOL. 428. ISSUE 1. P. 31-35 17 68% 9
6 YANG, J , VAIS, H , GU, WE , FOSKETT, JK , (2016) BIPHASIC REGULATION OF INSP(3) RECEPTOR GATING BY DUAL CA2+ RELEASE CHANNEL BH3-LIKE DOMAINS MEDIATES BCL-X(L) CONTROL OF CELL VIABILITY.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. VOL. 113. ISSUE 13. P. E1953 -E1962 21 44% 2
7 MONACO, G , DECROCK, E , AKL, H , PONSAERTS, R , VERVLIET, T , LUYTEN, T , DE MAEYER, M , MISSIAEN, L , DISTELHORST, CW , DE SMEDT, H , ET AL (2012) SELECTIVE REGULATION OF IP3-RECEPTOR-MEDIATED CA2+ SIGNALING AND APOPTOSIS BY THE BH4 DOMAIN OF BCL-2 VERSUS BCL-XL.CELL DEATH AND DIFFERENTIATION. VOL. 19. ISSUE 2. P. 295-309 20 44% 52
8 MONACO, G , VERVLIET, T , AKL, H , BULTYNCK, G , (2013) THE SELECTIVE BH4-DOMAIN BIOLOGY OF BCL-2-FAMILY MEMBERS: IP(3)RS AND BEYOND.CELLULAR AND MOLECULAR LIFE SCIENCES. VOL. 70. ISSUE 7. P. 1171-1183 37 27% 8
9 BONNEAU, B , PRUDENT, J , POPGEORGIEV, N , GILLET, G , (2013) NON-APOPTOTIC ROLES OF BCL-2 FAMILY: THE CALCIUM CONNECTION.BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH. VOL. 1833. ISSUE 7. P. 1755-1765 36 24% 33
10 DISTELHORST, CW , SHORE, GC , (2004) BCL-2 AND CALCIUM: CONTROVERSY BENEATH THE SURFACE.ONCOGENE. VOL. 23. ISSUE 16. P. 2875-2880 23 46% 78

Classes with closest relation at Level 1


Rank Class id link
1 640 MCL 1//BCL 2 FAMILY//BH3 MIMETIC
2 1887 INOSITOL 1 4 5 TRISPHOSPHATE RECEPTOR//CALCIUM OSCILLATIONS//IP3 RECEPTOR
3 1622 PERMEABILITY TRANSITION//CYCLOPHILIN D//PERMEABILITY TRANSITION PORE
4 23738 M 3M3FBS//CHRON DIS HLTH PROMOT//FURA 2
5 415 UNFOLDED PROTEIN RESPONSE//ENDOPLASMIC RETICULUM STRESS//ER STRESS
6 3694 APOPTOSIS//HIGH MOLECULAR WEIGHT DNA FRAGMENTATION//ENDONUCLEASE
7 33210 PARAPTOSIS//BAP31//AIP1 ALIX
8 19190 CALHM1//CALCIUM HOMEOSTASIS MODULATOR 1//MOL NEUROPATHOGENESIS
9 36759 PHARMACEUT CARE CLIN PHARM//BISABOLOLOXIDE A//INTRACELLULAR ZN2
10 707 STIM1//ORAI1//STORE OPERATED CALCIUM ENTRY

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