Class information for:
Level 1: 3 HYDROXYISOBUTYRATE DEHYDROGENASE//ECHS1//3 HYDROXYISOBUTYRIC ACID

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
28675 201 19.4 63%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
389 3       PEROXISOME//CARNITINE//JOURNAL OF INHERITED METABOLIC DISEASE 30841
2144 2             JOURNAL OF INHERITED METABOLIC DISEASE//NEWBORN SCREENING//METHYLMALONIC ACIDEMIA 5035
28675 1                   3 HYDROXYISOBUTYRATE DEHYDROGENASE//ECHS1//3 HYDROXYISOBUTYRIC ACID 201

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 3 HYDROXYISOBUTYRATE DEHYDROGENASE authKW 883879 4% 73% 8
2 ECHS1 authKW 607666 3% 67% 6
3 3 HYDROXYISOBUTYRIC ACID authKW 455753 1% 100% 3
4 HIBCH authKW 455753 1% 100% 3
5 SERINE DEHYDROGENASE authKW 455753 1% 100% 3
6 LACTONOHYDROLASE authKW 345262 2% 45% 5
7 3 HYDROXYISOBUTYRIC ACIDURIA authKW 303835 1% 100% 2
8 D BETA HYDROXYISOBUTYRIC ACID authKW 303835 1% 100% 2
9 D LACTONOHYDROLASE authKW 303835 1% 100% 2
10 D PANTONOHYDROLASE authKW 303835 1% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Biotechnology & Applied Microbiology 654 25% 0% 50
2 Biochemistry & Molecular Biology 262 32% 0% 65
3 Chemistry, Applied 138 8% 0% 17
4 Food Science & Technology 122 10% 0% 20
5 Genetics & Heredity 122 11% 0% 23
6 Engineering, Chemical 109 11% 0% 22
7 Medicine, Research & Experimental 90 9% 0% 18
8 Crystallography 52 5% 0% 10
9 Biochemical Research Methods 37 5% 0% 11
10 Endocrinology & Metabolism 30 6% 0% 12

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PROD DEV HIGASHI KU 202555 1% 67% 2
2 BIO OURCE SCI PL MICROBIOL 151918 0% 100% 1
3 BIO OURCE SCI PL MICROBIOL NANKO KU 151918 0% 100% 1
4 CENT 311 SAKURAI SHIMAMOTO 151918 0% 100% 1
5 DRUG CHILD HEALTH NEUROFARBA 151918 0% 100% 1
6 EMIL ERLENMEYER FORUM 151918 0% 100% 1
7 HEAD GENET METAB DIS 151918 0% 100% 1
8 HEAD OFF CYUO KU 151918 0% 100% 1
9 HOSP NEUROL SURG 151918 0% 100% 1
10 SOZIALPADIATR ZENTRUM NEUROPADIATRIE 151918 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY 1807 6% 0% 12
2 JOURNAL OF FERMENTATION TECHNOLOGY 1676 1% 0% 3
3 JOURNAL OF INHERITED METABOLIC DISEASE 1636 3% 0% 7
4 CRYSTAL ENGINEERING 1517 0% 1% 1
5 ORPHANET JOURNAL OF RARE DISEASES 1226 1% 0% 3
6 KAGAKU KOGAKU RONBUNSHU 1216 3% 0% 6
7 MOLECULAR GENETICS AND METABOLISM 773 2% 0% 4
8 JOURNAL OF INCLUSION PHENOMENA AND MOLECULAR RECOGNITION IN CHEMISTRY 758 1% 0% 2
9 CANCER MEDICINE 680 1% 0% 2
10 APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 527 3% 0% 7

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 3 HYDROXYISOBUTYRATE DEHYDROGENASE 883879 4% 73% 8 Search 3+HYDROXYISOBUTYRATE+DEHYDROGENASE Search 3+HYDROXYISOBUTYRATE+DEHYDROGENASE
2 ECHS1 607666 3% 67% 6 Search ECHS1 Search ECHS1
3 3 HYDROXYISOBUTYRIC ACID 455753 1% 100% 3 Search 3+HYDROXYISOBUTYRIC+ACID Search 3+HYDROXYISOBUTYRIC+ACID
4 HIBCH 455753 1% 100% 3 Search HIBCH Search HIBCH
5 SERINE DEHYDROGENASE 455753 1% 100% 3 Search SERINE+DEHYDROGENASE Search SERINE+DEHYDROGENASE
6 LACTONOHYDROLASE 345262 2% 45% 5 Search LACTONOHYDROLASE Search LACTONOHYDROLASE
7 3 HYDROXYISOBUTYRIC ACIDURIA 303835 1% 100% 2 Search 3+HYDROXYISOBUTYRIC+ACIDURIA Search 3+HYDROXYISOBUTYRIC+ACIDURIA
8 D BETA HYDROXYISOBUTYRIC ACID 303835 1% 100% 2 Search D+BETA+HYDROXYISOBUTYRIC+ACID Search D+BETA+HYDROXYISOBUTYRIC+ACID
9 D LACTONOHYDROLASE 303835 1% 100% 2 Search D+LACTONOHYDROLASE Search D+LACTONOHYDROLASE
10 D PANTONOHYDROLASE 303835 1% 100% 2 Search D+PANTONOHYDROLASE Search D+PANTONOHYDROLASE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 WANDERS, RJA , DURAN, M , LOUPATTY, FJ , (2012) ENZYMOLOGY OF THE BRANCHED-CHAIN AMINO ACID OXIDATION DISORDERS: THE VALINE PATHWAY.JOURNAL OF INHERITED METABOLIC DISEASE. VOL. 35. ISSUE 1. P. 5-12 20 56% 19
2 SASS, JO , WALTER, M , SHIELD, JPH , ATHERTON, AM , GARG, U , SCOTT, D , WOODS, CG , SMITH, LD , (2012) 3-HYDROXYISOBUTYRATE ACIDURIA AND MUTATIONS IN THE ALDH6A1 GENE CODING FOR METHYLMALONATE SEMIALDEHYDE DEHYDROGENASE.JOURNAL OF INHERITED METABOLIC DISEASE. VOL. 35. ISSUE 3. P. 437 -442 14 74% 9
3 MARCADIER, JL , SMITH, AM , POHL, D , SCHWARTZENTRUBER, J , AL-DIRBASHI, OY , MAJEWSKI, J , FERDINANDUSSE, S , WANDERS, RJA , BULMAN, DE , BOYCOTT, KM , ET AL (2013) MUTATIONS IN ALDH6A1 ENCODING METHYLMALONATE SEMIALDEHYDE DEHYDROGENASE ARE ASSOCIATED WITH DYSMYELINATION AND TRANSIENT METHYLMALONIC ACIDURIA.ORPHANET JOURNAL OF RARE DISEASES. VOL. 8. ISSUE . P. - 12 71% 4
4 TCHIGVINTSEV, A , SINGER, A , BROWN, G , FLICK, R , EVDOKIMOVA, E , TAN, KM , GONZALEZ, CF , SAVCHENKO, A , YAKUNIN, AF , (2012) BIOCHEMICAL AND STRUCTURAL STUDIES OF UNCHARACTERIZED PROTEIN PA0743 FROM PSEUDOMONAS AERUGINOSA REVEALED NAD(+)-DEPENDENT L-SERINE DEHYDROGENASE.JOURNAL OF BIOLOGICAL CHEMISTRY. VOL. 287. ISSUE 3. P. 1874 -1883 19 44% 9
5 PETERS, H , FERDINANDUSSE, S , RUITER, JP , WANDERS, RJA , BONEH, A , PITT, J , (2015) METABOLITE STUDIES IN HIBCH AND ECHS1 DEFECTS: IMPLICATIONS FOR SCREENING.MOLECULAR GENETICS AND METABOLISM. VOL. 115. ISSUE 4. P. 168 -173 12 63% 4
6 SCHOTTMANN, G , SARPONG, A , LORENZ, C , WEINHOLD, N , GILL, E , TESCHNER, L , FERDINANDUSSE, S , WANDERS, RJA , PRIGIONE, A , SCHUELKE, M , (2016) A MOVEMENT DISORDER WITH DYSTONIA AND ATAXIA CAUSED BY A MUTATION IN THE HIBCH GENE.MOVEMENT DISORDERS. VOL. 31. ISSUE 11. P. 1733 -1739 11 69% 0
7 HONDA, K , KATAOKA, M , SHIMIZU, S , (2002) ENZYMATIC PREPARATION OF D-BETA-ACETYLTHIOISOBUTYRIC ACID AND CETRAXATE HYDROCHLORIDE USING A STEREO- AND/OR REGIOSELECTIVE HYDROLASE, 3,4-DIHYDROCOUMARIN HYDROLASE FROM ACINETOBACTER CALCOACETICUS.APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. VOL. 60. ISSUE 3. P. 288-292 13 72% 7
8 LOUPATTY, FJ , VAN DER STEEN, A , IJLST, L , RUITER, JPN , OFMAN, R , BAUMGARTNER, MR , BALLHAUSEN, D , YAMAGUCHI, S , DURAN, M , WANDERS, RJA , (2006) CLINICAL, BIOCHEMICAL, AND MOLECULAR FINDINGS IN THREE PATIENTS WITH 3-HYDROXYISOBUTYRIC ACIDURIA.MOLECULAR GENETICS AND METABOLISM. VOL. 87. ISSUE 3. P. 243-248 10 77% 10
9 NAIR, P , HAMZEH, AR , MOHAMED, M , MALIK, EM , AL-ALI, MT , BASTAKI, F , (2016) NOVEL ECHS1 MUTATION IN AN EMIRATI NEONATE WITH SEVERE METABOLIC ACIDOSIS.METABOLIC BRAIN DISEASE. VOL. 31. ISSUE 5. P. 1189 -1192 7 88% 0
10 YAMADA, K , AIBA, K , KITAURA, Y , KONDO, Y , NOMURA, N , NAKAMURA, Y , FUKUSHI, D , MURAYAMA, K , SHIMOMURA, Y , PITT, J , ET AL (2015) CLINICAL, BIOCHEMICAL AND METABOLIC CHARACTERISATION OF A MILD FORM OF HUMAN SHORT-CHAIN ENOYL-COA HYDRATASE DEFICIENCY: SIGNIFICANCE OF INCREASED N-ACETYL-S-(2-CARBOXYPROPYL) CYSTEINE EXCRETION.JOURNAL OF MEDICAL GENETICS. VOL. 52. ISSUE 10. P. 691 -698 10 56% 4

Classes with closest relation at Level 1


Rank Class id link
1 23540 4 AMINOBUTYRATE AMINOTRANSFERASE//GAMMA AMINOBUTYRIC ACID AMINOTRANSFERASE//GABA AT
2 24942 3 HYDROXY 3 METHYLGLUTARIC ACIDURIA//3 METHYLGLUTACONIC ACIDURIA//3 METHYLGLUTARIC ACID
3 9764 MAPLE SYRUP URINE DISEASE//BRANCHED CHAIN ALPHA KETO ACID DEHYDROGENASE COMPLEX//BRANCHED CHAIN ALPHA KETOACID DEHYDROGENASE
4 32369 FORMOSE REACTION//3 HEXULOSES//HARZIALACTONE A
5 2343 ASYMMETRIC REDUCTION//CARBONYL REDUCTASE//CHIRAL ALCOHOLS
6 27588 BETA HYDROXY BETA METHYLBUTYRATE//HMB//METAB TECHNOL INC
7 19000 6 PHOSPHOGLUCONATE DEHYDROGENASE//GLUCOSE 6 PHOSPHATE DEHYDROGENASE//BIOTECHNOL PLICAT
8 22226 THREONINE DEHYDROGENASE//L THREONINE DEHYDROGENASE//TDC OPERON
9 25090 2 METHYLCITRIC ACID CYCLE//PROPIONATE METABOLISM//2 METHYLCITRATE SYNTHASE
10 27779 3 HYDROXYBUTYRATE DEHYDROGENASE//D BETA HYDROXYBUTYRATE DEHYDROGENASE//D 3 HYDROXYBUTYRATE DEHYDROGENASE

Go to start page