Class information for:
Level 1: MOL RECOGNIT SECT//ADENOSINE RECEPTORS//ADENOSINE RECEPTOR ANTAGONISTS

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
3075 2072 36.6 76%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
236 3       ADENOSINE//NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS//ADENOSINE RECEPTORS 48331
409 2             ADENOSINE//ADENOSINE RECEPTORS//ATP 16639
3075 1                   MOL RECOGNIT SECT//ADENOSINE RECEPTORS//ADENOSINE RECEPTOR ANTAGONISTS 2072

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MOL RECOGNIT SECT address 618472 6% 35% 120
2 ADENOSINE RECEPTORS authKW 606016 12% 17% 239
3 ADENOSINE RECEPTOR ANTAGONISTS authKW 249884 2% 40% 42
4 MOL MODELING SECT address 158841 1% 37% 29
5 ADENOSINE A3 RECEPTOR authKW 149352 2% 32% 32
6 LIGAND RECEPTOR MODELING STUDIES authKW 133956 0% 91% 10
7 A1 ADENOSINE RECEPTOR authKW 132314 2% 28% 32
8 ADENOSINE A1 RECEPTOR authKW 121009 3% 14% 60
9 TRICYCLIC HETEROAROMATIC SYSTEMS authKW 117883 0% 100% 8
10 A2B ANTAGONISTS authKW 103148 0% 100% 7

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Chemistry, Medicinal 20429 30% 0% 613
2 Pharmacology & Pharmacy 10071 41% 0% 854
3 Chemistry, Organic 934 11% 0% 229
4 Biochemistry & Molecular Biology 745 20% 0% 406
5 Physiology 283 5% 0% 104
6 Peripheral Vascular Diseases 98 3% 0% 58
7 Cardiac & Cardiovascular System 87 4% 0% 81
8 Biophysics 78 3% 0% 70
9 Neurosciences 65 6% 0% 125
10 Computer Science, Interdisciplinary Applications 17 1% 0% 30

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MOL RECOGNIT SECT 618472 6% 35% 120
2 MOL MODELING SECT 158841 1% 37% 29
3 SEZ FARMACOL 93757 2% 16% 41
4 LBC 71352 1% 19% 25
5 DIPARTIMENTO SCI FARMACEUT 59319 6% 3% 128
6 PHARMACEUT POPPELSDORF 51567 0% 50% 7
7 INTERNAL MED MOL PHYSIOL BIOL PHYS 47152 0% 80% 4
8 DRUG PHARMACOL SCI 47144 0% 40% 8
9 SEZ FARMACEUT NUTRACEUT 47144 0% 40% 8
10 DIPARTIMENTO MED CLIN SPERIMENTALE SEZ FARMACOL 44206 0% 100% 3

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF MEDICINAL CHEMISTRY 37218 11% 1% 233
2 DRUG DEVELOPMENT RESEARCH 17337 3% 2% 59
3 NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS 9832 3% 1% 56
4 PURINERGIC SIGNALLING 9757 1% 4% 17
5 NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 9271 3% 1% 62
6 BRITISH JOURNAL OF PHARMACOLOGY 8700 5% 1% 103
7 MOLECULAR PHARMACOLOGY 8400 4% 1% 75
8 BIOORGANIC & MEDICINAL CHEMISTRY 7339 4% 1% 81
9 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 4150 4% 0% 78
10 EUROPEAN JOURNAL OF PHARMACOLOGY 3585 4% 0% 84

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 ADENOSINE RECEPTORS 606016 12% 17% 239 Search ADENOSINE+RECEPTORS Search ADENOSINE+RECEPTORS
2 ADENOSINE RECEPTOR ANTAGONISTS 249884 2% 40% 42 Search ADENOSINE+RECEPTOR+ANTAGONISTS Search ADENOSINE+RECEPTOR+ANTAGONISTS
3 ADENOSINE A3 RECEPTOR 149352 2% 32% 32 Search ADENOSINE+A3+RECEPTOR Search ADENOSINE+A3+RECEPTOR
4 LIGAND RECEPTOR MODELING STUDIES 133956 0% 91% 10 Search LIGAND+RECEPTOR+MODELING+STUDIES Search LIGAND+RECEPTOR+MODELING+STUDIES
5 A1 ADENOSINE RECEPTOR 132314 2% 28% 32 Search A1+ADENOSINE+RECEPTOR Search A1+ADENOSINE+RECEPTOR
6 ADENOSINE A1 RECEPTOR 121009 3% 14% 60 Search ADENOSINE+A1+RECEPTOR Search ADENOSINE+A1+RECEPTOR
7 TRICYCLIC HETEROAROMATIC SYSTEMS 117883 0% 100% 8 Search TRICYCLIC+HETEROAROMATIC+SYSTEMS Search TRICYCLIC+HETEROAROMATIC+SYSTEMS
8 A2B ANTAGONISTS 103148 0% 100% 7 Search A2B+ANTAGONISTS Search A2B+ANTAGONISTS
9 A2B ADENOSINE RECEPTOR 102273 1% 37% 19 Search A2B+ADENOSINE+RECEPTOR Search A2B+ADENOSINE+RECEPTOR
10 XANTHINES 81311 1% 20% 28 Search XANTHINES Search XANTHINES

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 CRISTALLI, G , LAMBERTUCCI, C , MARUCCI, G , VOLPINI, R , DAL BEN, D , (2008) A(2A) ADENOSINE RECEPTOR AND ITS MODULATORS: OVERVIEW ON A DRUGGABLE GPCR AND ON STRUCTURE-ACTIVITY RELATIONSHIP ANALYSIS AND BINDING REQUIREMENTS OF AGONISTS AND ANTAGONISTS.CURRENT PHARMACEUTICAL DESIGN. VOL. 14. ISSUE 15. P. 1525-1552 153 60% 42
2 FREDHOLM, BB , IJZERMAN, AP , JACOBSON, KA , KLOTZ, KN , LINDEN, J , (2001) INTERNATIONAL UNION OF PHARMACOLOGY. XXV. NOMENCLATURE AND CLASSIFICATION OF ADENOSINE RECEPTORS.PHARMACOLOGICAL REVIEWS. VOL. 53. ISSUE 4. P. 527 -552 121 37% 1625
3 MORO, S , GAO, ZG , JACOBSON, KA , SPALLUTO, G , (2006) PROGRESS IN THE PURSUIT OF THERAPEUTIC ADENOSINE RECEPTOR ANTAGONISTS.MEDICINAL RESEARCH REVIEWS. VOL. 26. ISSUE 2. P. 131-159 104 76% 107
4 CRISTALLI, G , CACCIARI, B , DAL BEN, D , LAMBERTUCCI, C , MORO, S , SPALLUTO, G , VOLPINI, R , (2007) HIGHLIGHTS ON THE DEVELOPMENT OF A(2A) ADENOSINE RECEPTOR AGONISTS AND ANTAGONISTS.CHEMMEDCHEM. VOL. 2. ISSUE 3. P. 260 -281 125 71% 0
5 TALIANI, S , PUGLIESI, I , BELLANDI, M , LA MOTTA, C , DA SETTIMO, F , (2010) A(3) RECEPTOR LIGANDS: PAST, PRESENT AND FUTURE TRENDS.CURRENT TOPICS IN MEDICINAL CHEMISTRY. VOL. 10. ISSUE 10. P. 942-975 89 85% 10
6 DAL BEN, D , LAMBERTUCCI, C , MARUCCI, G , VOLPINI, R , CRISTALLI, G , (2010) ADENOSINE RECEPTOR MODELING: WHAT DOES THE A(2A) CRYSTAL STRUCTURE TELL US?.CURRENT TOPICS IN MEDICINAL CHEMISTRY. VOL. 10. ISSUE 10. P. 993-1018 106 67% 21
7 CHEONG, SL , FEDERICO, S , VENKATESAN, G , MANDEL, AL , SHAO, YM , MORO, S , SPALLUTO, G , PASTORIN, G , (2013) THE A3 ADENOSINE RECEPTOR AS MULTIFACETED THERAPEUTIC TARGET: PHARMACOLOGY, MEDICINAL CHEMISTRY, AND IN SILICO APPROACHES.MEDICINAL RESEARCH REVIEWS. VOL. 33. ISSUE 2. P. 235-335 143 44% 15
8 MULLER, CE , JACOBSON, KA , (2011) RECENT DEVELOPMENTS IN ADENOSINE RECEPTOR LIGANDS AND THEIR POTENTIAL AS NOVEL DRUGS.BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. VOL. 1808. ISSUE 5. P. 1290 -1308 88 53% 117
9 POULSEN, SA , QUINN, RJ , (1998) ADENOSINE RECEPTORS: NEW OPPORTUNITIES FOR FUTURE DRUGS.BIOORGANIC & MEDICINAL CHEMISTRY. VOL. 6. ISSUE 6. P. 619 -641 99 67% 248
10 GONZALEZ, MP , TERAN, C , TEIJEIRA, M , (2008) SEARCH FOR NEW ANTAGONIST LIGANDS FOR ADENOSINE RECEPTORS FROM QSAR POINT OF VIEW. HOW CLOSE ARE WE?.MEDICINAL RESEARCH REVIEWS. VOL. 28. ISSUE 3. P. 329-371 104 59% 11

Classes with closest relation at Level 1


Rank Class id link
1 1134 ADENOSINE A2A RECEPTOR//ADENOSINE//A2A RECEPTOR
2 4306 CD73//ADENOSINE RECEPTORS//ADENOSINE
3 18367 DOXOFYLLINE//1 METHYL 3 PROPYL 7 BUTYLXANTHINE//7 THEOPHYLLINE ACETIC ACID
4 10559 ADENOSINE//RECEPTORIAL RESPONSIVENESS METHOD//PHENYLISOPROPYLADENOSINE
5 12351 KW 3902//ADENOSINE A1 RECEPTOR ANTAGONIST//2 AMP
6 32378 FLUORESCENT LIGANDS//1012 S//ALEXA FLUOR R 647
7 19498 ADENOSINE//ADENOSINE KINASE//5 DEOXY 5 IODOTUBERCIDIN
8 17042 NUCLEOSIDE TRANSPORT INHIBITION//DRAFLAZINE//ENDOTHELIAL CONTROL
9 31316 ADENOSINE 5 O 2 THIODIPHOSPHATE ADP BETA S//UNIT UP EA 1677//2 METHYLTHIOADENOSINE
10 31866 EHU MED FISIOL POB 699//RABBIT PARIETAL CELLS//ATP ATP ANALOGS

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