Class information for:
Level 1: BIOORTHOGONAL REACTIONS//BIOORTHOGONAL CHEMISTRY//NONCANONICAL AMINO ACIDS

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
3192 2042 46.4 89%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
478 3       PHAGE DISPLAY//CELL FREE PROTEIN SYNTHESIS//ANTIBODY ENGINEERING 23687
1537 2             CELL FREE PROTEIN SYNTHESIS//INTEIN//PROTEIN SPLICING 7453
3192 1                   BIOORTHOGONAL REACTIONS//BIOORTHOGONAL CHEMISTRY//NONCANONICAL AMINO ACIDS 2042

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOORTHOGONAL REACTIONS authKW 456963 2% 75% 41
2 BIOORTHOGONAL CHEMISTRY authKW 418047 2% 59% 47
3 NONCANONICAL AMINO ACIDS authKW 345536 2% 54% 43
4 GENETIC CODE EXPANSION authKW 325630 2% 66% 33
5 PYRROLYSINE authKW 316805 1% 76% 28
6 PYRROLYSYL TRNA SYNTHETASE authKW 269880 1% 95% 19
7 UNNATURAL AMINO ACIDS authKW 268686 4% 22% 82
8 CYCLOOCTYNE authKW 187865 1% 74% 17
9 METABOLIC OLIGOSACCHARIDE ENGINEERING authKW 183157 1% 88% 14
10 BIOORTHOGONAL authKW 168265 1% 49% 23

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Chemistry, Multidisciplinary 9554 44% 0% 907
2 Biochemistry & Molecular Biology 3746 37% 0% 762
3 Chemistry, Organic 2954 18% 0% 374
4 Chemistry, Medicinal 1787 9% 0% 192
5 Biochemical Research Methods 1323 9% 0% 190
6 Biophysics 168 4% 0% 90
7 Biotechnology & Applied Microbiology 20 3% 0% 60
8 Materials Science, Biomaterials 10 1% 0% 13
9 Cell Biology 5 3% 0% 63
10 Cell & Tissue Engineering 0 0% 0% 2

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SYNTHET FUNCT BIOMOL 96425 1% 28% 23
2 CHEM BIOL SIGNAL TRANSDUCT 74230 1% 41% 12
3 JACK H SKIRBALL CHEM BIOL PROTE 73215 1% 29% 17
4 EMMY NOETHER GRP NEURAL 59808 0% 100% 4
5 BIOL INTER ES IBG I 44856 0% 100% 3
6 SKAGGS CHEM BIOL 36173 5% 3% 97
7 BIOFUTURE INDEPENDENT GRP 29904 0% 100% 2
8 CHEM BIOCATALYSIS 29904 0% 100% 2
9 LENDULET CHEM BIOL GRP 29904 0% 100% 2
10 MOL NETWORK CONTROL PROJECT 29904 0% 100% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CHEMBIOCHEM 46734 6% 3% 118
2 BIOCONJUGATE CHEMISTRY 27560 5% 2% 96
3 ACS CHEMICAL BIOLOGY 15299 2% 2% 47
4 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 12218 9% 0% 179
5 CURRENT OPINION IN CHEMICAL BIOLOGY 9690 2% 2% 35
6 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 8218 11% 0% 228
7 NATURE CHEMICAL BIOLOGY 7332 1% 2% 26
8 CHEMICAL SCIENCE 7070 2% 1% 43
9 CHEMICAL COMMUNICATIONS 5243 6% 0% 124
10 ORGANIC & BIOMOLECULAR CHEMISTRY 4992 3% 1% 63

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 BIOORTHOGONAL REACTIONS 456963 2% 75% 41 Search BIOORTHOGONAL+REACTIONS Search BIOORTHOGONAL+REACTIONS
2 BIOORTHOGONAL CHEMISTRY 418047 2% 59% 47 Search BIOORTHOGONAL+CHEMISTRY Search BIOORTHOGONAL+CHEMISTRY
3 NONCANONICAL AMINO ACIDS 345536 2% 54% 43 Search NONCANONICAL+AMINO+ACIDS Search NONCANONICAL+AMINO+ACIDS
4 GENETIC CODE EXPANSION 325630 2% 66% 33 Search GENETIC+CODE+EXPANSION Search GENETIC+CODE+EXPANSION
5 PYRROLYSINE 316805 1% 76% 28 Search PYRROLYSINE Search PYRROLYSINE
6 PYRROLYSYL TRNA SYNTHETASE 269880 1% 95% 19 Search PYRROLYSYL+TRNA+SYNTHETASE Search PYRROLYSYL+TRNA+SYNTHETASE
7 UNNATURAL AMINO ACIDS 268686 4% 22% 82 Search UNNATURAL+AMINO+ACIDS Search UNNATURAL+AMINO+ACIDS
8 CYCLOOCTYNE 187865 1% 74% 17 Search CYCLOOCTYNE Search CYCLOOCTYNE
9 METABOLIC OLIGOSACCHARIDE ENGINEERING 183157 1% 88% 14 Search METABOLIC+OLIGOSACCHARIDE+ENGINEERING Search METABOLIC+OLIGOSACCHARIDE+ENGINEERING
10 BIOORTHOGONAL 168265 1% 49% 23 Search BIOORTHOGONAL Search BIOORTHOGONAL

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 LANG, K , CHIN, JW , (2014) CELLULAR INCORPORATION OF UNNATURAL AMINO ACIDS AND BIOORTHOGONAL LABELING OF PROTEINS.CHEMICAL REVIEWS. VOL. 114. ISSUE 9. P. 4764 -4806 218 63% 154
2 DUMAS, A , LERCHER, L , SPICER, CD , DAVIS, BG , (2015) DESIGNING LOGICAL CODON REASSIGNMENT - EXPANDING THE CHEMISTRY IN BIOLOGY.CHEMICAL SCIENCE. VOL. 6. ISSUE 1. P. 50 -69 179 85% 37
3 PATTERSON, DM , NAZAROVA, LA , PRESCHER, JA , (2014) FINDING THE RIGHT (BIOORTHOGONAL) CHEMISTRY.ACS CHEMICAL BIOLOGY. VOL. 9. ISSUE 3. P. 592-605 149 74% 161
4 MCKAY, CS , FINN, MG , (2014) CLICK CHEMISTRY IN COMPLEX MIXTURES: BIOORTHOGONAL BIOCONJUGATION.CHEMISTRY & BIOLOGY. VOL. 21. ISSUE 9. P. 1075 -1101 183 66% 94
5 BOUTUREIRA, O , BERNARDES, GJL , (2015) ADVANCES IN CHEMICAL PROTEIN MODIFICATION.CHEMICAL REVIEWS. VOL. 115. ISSUE 5. P. 2174 -2195 158 57% 81
6 LIU, CC , SCHULTZ, PG , (2010) ADDING NEW CHEMISTRIES TO THE GENETIC CODE.ANNUAL REVIEW OF BIOCHEMISTRY, VOL 79. VOL. 79. ISSUE . P. 413-444 114 65% 576
7 SPICER, CD , DAVIS, BG , (2014) SELECTIVE CHEMICAL PROTEIN MODIFICATION.NATURE COMMUNICATIONS. VOL. 5. ISSUE . P. - 124 69% 90
8 MAYER, S , LANG, K , (2017) TETRAZINES IN INVERSE-ELECTRON-DEMAND DIELS-ALDER CYCLOADDITIONS AND THEIR USE IN BIOLOGY.SYNTHESIS-STUTTGART. VOL. 49. ISSUE 4. P. 830 -848 158 80% 0
9 RAMIL, CP , LIN, Q , (2013) BIOORTHOGONAL CHEMISTRY: STRATEGIES AND RECENT DEVELOPMENTS.CHEMICAL COMMUNICATIONS. VOL. 49. ISSUE 94. P. 11007-11022 99 81% 102
10 AGRAWAL, D , HACKENBERGER, CPR , (2013) SITE-SPECIFIC CHEMICAL MODIFICATIONS OF PROTEINS.INDIAN JOURNAL OF CHEMISTRY SECTION A-INORGANIC BIO-INORGANIC PHYSICAL THEORETICAL & ANALYTICAL CHEMISTRY. VOL. 52. ISSUE 8-9. P. 973 -991 183 66% 3

Classes with closest relation at Level 1


Rank Class id link
1 19599 MOL BIOSENSOR IMAGING//FLUOROGEN ACTIVATING PROTEIN//FLUOROGEN
2 14625 RIBOSOME DISPLAY//MRNA DISPLAY//FOUR BASE CODON
3 17844 GILEAD IOCB//REVERSIBLE TERMINATOR//LIFE SCI SOLUT GRP
4 13434 CHEMICAL PROTEOMICS//ACTIVITY BASED PROTEIN PROFILING//ACTIVITY BASED PROBES
5 1510 1 2 3 TRIAZOLE//CLICK CHEMISTRY//TRIAZOLE
6 5605 NATIVE CHEMICAL LIGATION//PEPTIDE THIOESTER//DIFFICULT SEQUENCE
7 11281 ANTIBODY DRUG CONJUGATE//GEMTUZUMAB OZOGAMICIN//MYLOTARG
8 24561 PROTEIN POLYMER CONJUGATE//PROTEIN POLYMER HYBRIDS//CBSA 147
9 37467 CHEM BIOL SECT//IN VITRO SENSING//EXPT PHYSIOL MED SECT
10 19390 ARTIFICIAL METALLOENZYMES//BIOHYBRID CATALYSIS//CHEMOGENETIC OPTIMIZATION

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