Class information for:
Level 1: GILEAD IOCB//REVERSIBLE TERMINATOR//LIFE SCI SOLUT GRP

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
17844 580 37.7 83%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
5 4 CHEMISTRY, ORGANIC//CHEMISTRY, INORGANIC & NUCLEAR//CHEMISTRY, MULTIDISCIPLINARY 1745167
183 3       APTAMER//G QUADRUPLEX//RIBOZYME 56307
389 2             NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS//OLIGONUCLEOTIDES//PEPTIDE NUCLEIC ACID 16949
17844 1                   GILEAD IOCB//REVERSIBLE TERMINATOR//LIFE SCI SOLUT GRP 580

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 GILEAD IOCB address 380080 3% 38% 19
2 REVERSIBLE TERMINATOR authKW 286625 1% 78% 7
3 LIFE SCI SOLUT GRP address 239289 2% 45% 10
4 BIOORGAN CHEM CHEM BIOL address 233951 3% 22% 20
5 NUCLEOSIDE TRIPHOSPHATES authKW 213903 3% 25% 16
6 CHEM BRANCH address 191407 3% 18% 20
7 ONE POT METHODOLOGY authKW 188018 1% 71% 5
8 SEQUENCING BY SYNTHESIS authKW 159519 2% 30% 10
9 2 NITROBENZYL LINKER authKW 157938 1% 100% 3
10 CYCLOSAL APPROACH authKW 157938 1% 100% 3

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Chemistry, Organic 5452 44% 0% 254
2 Chemistry, Multidisciplinary 1353 32% 0% 188
3 Chemistry, Medicinal 900 12% 0% 71
4 Biochemistry & Molecular Biology 704 31% 0% 182
5 Biochemical Research Methods 157 6% 0% 37
6 Chemistry, Analytical 7 3% 0% 18
7 Chemistry, Applied 1 1% 0% 7
8 Biophysics -1 1% 0% 5
9 Chemistry, Inorganic & Nuclear -1 1% 0% 4
10 Biotechnology & Applied Microbiology -1 1% 0% 6

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 GILEAD IOCB 380080 3% 38% 19
2 LIFE SCI SOLUT GRP 239289 2% 45% 10
3 BIOORGAN CHEM CHEM BIOL 233951 3% 22% 20
4 CHEM BRANCH 191407 3% 18% 20
5 GILEAD SCI IOCB 150735 4% 13% 22
6 HIGH LEVEL ENGN BIOPHARMACEUT MOL DIAGN 87737 1% 33% 5
7 KONSTANZ CHEM BIOL 76457 3% 8% 18
8 PETR MIN ENGN 71682 3% 7% 19
9 AREMSUMR CNRS UHP 7214 52646 0% 100% 1
10 BIOMED PCB 52646 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS 20858 7% 1% 43
2 CHEMBIOCHEM 6237 4% 1% 23
3 ORGANIC & BIOMOLECULAR CHEMISTRY 4878 6% 0% 33
4 BIOCONJUGATE CHEMISTRY 4633 4% 0% 21
5 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 1721 5% 0% 29
6 ORGANIC LETTERS 1590 5% 0% 28
7 CHEMICAL COMMUNICATIONS 1303 6% 0% 33
8 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 1266 5% 0% 31
9 JOURNAL OF ORGANIC CHEMISTRY 1147 6% 0% 34
10 CHEMISTRY-A EUROPEAN JOURNAL 1061 4% 0% 22

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 REVERSIBLE TERMINATOR 286625 1% 78% 7 Search REVERSIBLE+TERMINATOR Search REVERSIBLE+TERMINATOR
2 NUCLEOSIDE TRIPHOSPHATES 213903 3% 25% 16 Search NUCLEOSIDE+TRIPHOSPHATES Search NUCLEOSIDE+TRIPHOSPHATES
3 ONE POT METHODOLOGY 188018 1% 71% 5 Search ONE+POT+METHODOLOGY Search ONE+POT+METHODOLOGY
4 SEQUENCING BY SYNTHESIS 159519 2% 30% 10 Search SEQUENCING+BY+SYNTHESIS Search SEQUENCING+BY+SYNTHESIS
5 2 NITROBENZYL LINKER 157938 1% 100% 3 Search 2+NITROBENZYL+LINKER Search 2+NITROBENZYL+LINKER
6 CYCLOSAL APPROACH 157938 1% 100% 3 Search CYCLOSAL+APPROACH Search CYCLOSAL+APPROACH
7 DINUCLEOSIDE DIPHOSPHATE 157938 1% 100% 3 Search DINUCLEOSIDE+DIPHOSPHATE Search DINUCLEOSIDE+DIPHOSPHATE
8 GLYCOPHOSPHOTRANSFERASES 157938 1% 100% 3 Search GLYCOPHOSPHOTRANSFERASES Search GLYCOPHOSPHOTRANSFERASES
9 DNA SEQUENCING BY SYNTHESIS 120330 1% 57% 4 Search DNA+SEQUENCING+BY+SYNTHESIS Search DNA+SEQUENCING+BY+SYNTHESIS
10 PHOSPHOROPIPERIDATE 120330 1% 57% 4 Search PHOSPHOROPIPERIDATE Search PHOSPHOROPIPERIDATE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 HOCEK, M , (2014) SYNTHESIS OF BASE-MODIFIED 2 '-DEOXYRIBONUCLEOSIDE TRIPHOSPHATES AND THEIR USE IN ENZYMATIC SYNTHESIS OF MODIFIED DNA FOR APPLICATIONS IN BIOANALYSIS AND CHEMICAL BIOLOGY.JOURNAL OF ORGANIC CHEMISTRY. VOL. 79. ISSUE 21. P. 9914 -9921 63 69% 20
2 HOCEK, M , (2014) PREPARATION OF BASE-MODIFIED DNA BY ENZYMATIC INCORPORATION OF MODIFIED NUCLEOSIDE TRIPHOSPHATES.CHEMICKE LISTY. VOL. 108. ISSUE 4. P. 320-325 40 82% 0
3 HOLLENSTEIN, M , (2012) NUCLEOSIDE TRIPHOSPHATES - BUILDING BLOCKS FOR THE MODIFICATION OF NUCLEIC ACIDS.MOLECULES. VOL. 17. ISSUE 11. P. 13569 -13591 59 44% 44
4 RAINDLOVA, V , POHL, R , KLEPETAROVA, B , HAVRAN, L , SIMKOVA, E , HORAKOVA, P , PIVONKOVA, H , FOJTA, M , HOCEK, M , (2012) SYNTHESIS OF HYDRAZONE-MODIFIED NUCLEOTIDES AND THEIR POLYMERASE INCORPORATION ONTO DNA FOR REDOX LABELING.CHEMPLUSCHEM. VOL. 77. ISSUE 8. P. 652 -662 37 74% 7
5 ROY, B , DEPAIX, A , PERIGAUD, C , PEYROTTES, S , (2016) RECENT TRENDS IN NUCLEOTIDE SYNTHESIS.CHEMICAL REVIEWS. VOL. 116. ISSUE 14. P. 7854 -7897 68 32% 2
6 HOTTIN, A , MARX, A , (2016) STRUCTURAL INSIGHTS INTO THE PROCESSING OF NUCLEOBASE-MODIFIED NUCLEOTIDES BY DNA POLYMERASES.ACCOUNTS OF CHEMICAL RESEARCH. VOL. 49. ISSUE 3. P. 418 -427 29 50% 11
7 SHERSTYUK, YV , ABRAMOVA, TV , (2015) HOW TO FORM A PHOSPHATE ANHYDRIDE LINKAGE IN NUCLEOTIDE DERIVATIVES.CHEMBIOCHEM. VOL. 16. ISSUE 18. P. 2562 -2570 50 45% 4
8 MENOVA, P , RAINDLOVA, V , HOCEK, M , (2013) SCOPE AND LIMITATIONS OF THE NICKING ENZYME AMPLIFICATION REACTION FOR THE SYNTHESIS OF BASE-MODIFIED OLIGONUCLEOTIDES AND PRIMERS FOR PCR.BIOCONJUGATE CHEMISTRY. VOL. 24. ISSUE 6. P. 1081 -1093 36 68% 4
9 MACKOVA, M , BOHACOVA, S , PERLIKOVA, P , SLAVETINSKA, LP , HOCEK, M , (2015) POLYMERASE SYNTHESIS AND RESTRICTION ENZYME CLEAVAGE OF DNA CONTAINING 7-SUBSTITUTED 7-DEAZAGUANINE NUCLEOBASES.CHEMBIOCHEM. VOL. 16. ISSUE 15. P. 2225 -2236 36 61% 3
10 FOMICH, MA , KVACH, MV , NAVAKOUSKI, MJ , WEISE, C , BARANOVSKY, AV , KORSHUN, VA , SHMANAI, VV , (2014) AZIDE PHOSPHORAMIDITE IN DIRECT SYNTHESIS OF AZIDE-MODIFIED OLIGONUCLEOTIDES.ORGANIC LETTERS. VOL. 16. ISSUE 17. P. 4590 -4593 38 57% 5

Classes with closest relation at Level 1


Rank Class id link
1 36765 PROGRAM BIOCHEM CHEM//2 SELENOURIDINE TRIPHOSPHATE//3 5 O DIACETYL 5 AMINOMETHYL 2 DEOXYURIDINE
2 9916 NEWCAT//WOLFSON RAT STRUCT BASED DESIGN MOL DIAGNOST//CHEM BIOL PL CHEM
3 11256 DEOXYRIBOZYME//DNAZYME//CATALYTIC DNA
4 12678 ORGAN BIOORGAN CHEM//BIOORGAN CHEM CHEM BIOL//7 DEAZAPURINES
5 21062 DNA ENCODED LIBRARY//DNA ENCODED CHEMICAL LIBRARY//TEMPLATED REACTIONS
6 23595 4 THIOTHYMIDINE//ORGAN BIOMIMET CHEM//2 DEOXY 6 THIOGUANOSINE
7 9408 METAL MEDIATED BASE PAIRS//UNNATURAL BASE PAIRS//METALLO BASE PAIR
8 9258 OLIGONUCLEOTIDE PEPTIDE CONJUGATES//NUCLEOPEPTIDES//PEPTIDE OLIGONUCLEOTIDE CONJUGATE
9 3192 BIOORTHOGONAL REACTIONS//BIOORTHOGONAL CHEMISTRY//NONCANONICAL AMINO ACIDS
10 4600 NUCLE ACID//SYNTHET BIOORGAN CHEM//NUCL ACID

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