Class information for:
Level 1: DEOXYRIBOZYME//DNAZYME//CATALYTIC DNA

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
11256 996 40.3 87%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
5 4 CHEMISTRY, ORGANIC//CHEMISTRY, INORGANIC & NUCLEAR//CHEMISTRY, MULTIDISCIPLINARY 1745167
183 3       APTAMER//G QUADRUPLEX//RIBOZYME 56307
1185 2             RIBOZYME//RNASE P//CATALYTIC RNA 9289
11256 1                   DEOXYRIBOZYME//DNAZYME//CATALYTIC DNA 996

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 DEOXYRIBOZYME authKW 1461356 7% 70% 68
2 DNAZYME authKW 1289925 14% 31% 137
3 CATALYTIC DNA authKW 540773 2% 84% 21
4 IN VITRO SELECTION authKW 462583 9% 18% 86
5 DNA ENZYME authKW 343792 3% 42% 27
6 10 23 DNAZYME authKW 309117 1% 92% 11
7 RIBOZYME authKW 201523 9% 7% 94
8 RNASE V1 authKW 187769 1% 88% 7
9 RNA CLEAVAGE authKW 157012 3% 20% 25
10 NUCLEIC ACID CATALYSIS authKW 122626 0% 100% 4

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Biochemistry & Molecular Biology 4356 55% 0% 544
2 Chemistry, Multidisciplinary 654 19% 0% 188
3 Chemistry, Medicinal 272 6% 0% 56
4 Biotechnology & Applied Microbiology 207 8% 0% 75
5 Biophysics 186 6% 0% 60
6 Chemistry, Organic 142 7% 0% 70
7 Evolutionary Biology 122 3% 0% 27
8 Biochemical Research Methods 114 5% 0% 45
9 Cell Biology 89 7% 0% 69
10 Genetics & Heredity 36 4% 0% 40

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 WCU BRL PROGRAM 61313 0% 100% 2
2 MAX PLANCK GRP NUCLE ACID CHEM 45982 0% 50% 3
3 GRP NUCLE ACID CHEM 42571 1% 28% 5
4 ADV TECHNOL TRANSPLANT 30656 0% 100% 1
5 CARCINOGENESI INESE MINIST PUBL HLTHC 30656 0% 100% 1
6 CHANGCHUN WOMEN CHILDRENS HLTH 30656 0% 100% 1
7 CHARITE MED FAK PEDIAT ONCOL HEMATOL 30656 0% 100% 1
8 CHEM CHEM ENGN BIOL ABORAT 30656 0% 100% 1
9 GRP NUCL ACID CHEM 30656 0% 100% 1
10 HEMATOL ONCOL STEM CELLS BLOOD DISORDERS 30656 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 OLIGONUCLEOTIDES 32904 2% 6% 17
2 CHEMISTRY & BIOLOGY 17459 4% 1% 39
3 RNA-A PUBLICATION OF THE RNA SOCIETY 9609 2% 2% 20
4 RNA 8137 3% 1% 26
5 JOURNAL OF MOLECULAR EVOLUTION 3516 2% 1% 21
6 NUCLEIC ACIDS RESEARCH 3510 7% 0% 68
7 CHEMBIOCHEM 3303 2% 0% 22
8 NUCLEIC ACID THERAPEUTICS 1923 0% 2% 4
9 NATURE STRUCTURAL BIOLOGY 1560 1% 1% 9
10 BIOCHEMISTRY 1544 5% 0% 53

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 DEOXYRIBOZYME 1461356 7% 70% 68 Search DEOXYRIBOZYME Search DEOXYRIBOZYME
2 DNAZYME 1289925 14% 31% 137 Search DNAZYME Search DNAZYME
3 CATALYTIC DNA 540773 2% 84% 21 Search CATALYTIC+DNA Search CATALYTIC+DNA
4 IN VITRO SELECTION 462583 9% 18% 86 Search IN+VITRO+SELECTION Search IN+VITRO+SELECTION
5 DNA ENZYME 343792 3% 42% 27 Search DNA+ENZYME Search DNA+ENZYME
6 10 23 DNAZYME 309117 1% 92% 11 Search 10+23+DNAZYME Search 10+23+DNAZYME
7 RIBOZYME 201523 9% 7% 94 Search RIBOZYME Search RIBOZYME
8 RNASE V1 187769 1% 88% 7 Search RNASE+V1 Search RNASE+V1
9 RNA CLEAVAGE 157012 3% 20% 25 Search RNA+CLEAVAGE Search RNA+CLEAVAGE
10 NUCLEIC ACID CATALYSIS 122626 0% 100% 4 Search NUCLEIC+ACID+CATALYSIS Search NUCLEIC+ACID+CATALYSIS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 HOLLENSTEIN, M , (2015) DNA CATALYSIS: THE CHEMICAL REPERTOIRE OF DNAZYMES.MOLECULES. VOL. 20. ISSUE 11. P. 20777 -20804 130 62% 10
2 FOKINA, AA , STETSENKO, DA , FRANCOIS, JC , (2015) DNA ENZYMES AS POTENTIAL THERAPEUTICS: TOWARDS CLINICAL APPLICATION OF 10-23 DNAZYMES.EXPERT OPINION ON BIOLOGICAL THERAPY. VOL. 15. ISSUE 5. P. 689 -711 103 75% 6
3 BAUM, DA , SILVERMAN, SK , (2008) DEOXYRIBOZYMES: USEFUL DNA CATALYSTS IN VITRO AND IN VIVO.CELLULAR AND MOLECULAR LIFE SCIENCES. VOL. 65. ISSUE 14. P. 2156 -2174 125 60% 88
4 HWANG, K , HOSSEINZADEH, P , LU, Y , (2016) BIOCHEMICAL AND BIOPHYSICAL UNDERSTANDING OF METAL ION SELECTIVITY OF DNAZYMES.INORGANICA CHIMICA ACTA. VOL. 452. ISSUE . P. 12 -24 78 69% 1
5 SCHLOSSER, K , LI, YF , (2009) BIOLOGICALLY INSPIRED SYNTHETIC ENZYMES MADE FROM DNA.CHEMISTRY & BIOLOGY. VOL. 16. ISSUE 3. P. 311-322 84 59% 119
6 ZHANG, WQ , FENG, Q , CHANG, DR , TRAM, K , LI, YF , (2016) IN VITRO SELECTION OF RNA-CLEAVING DNAZYMES FOR BACTERIAL DETECTION.METHODS. VOL. 106. ISSUE . P. 66 -75 65 70% 1
7 SILVERMAN, SK , (2005) IN VITRO SELECTION, CHARACTERIZATION, AND APPLICATION OF DEOXYRIBOZYMES THAT CLEAVE RNA.NUCLEIC ACIDS RESEARCH. VOL. 33. ISSUE 19. P. 6151-6163 89 58% 137
8 SILVERMAN, SK , (2016) CATALYIC DNA: SCOPE, APPLICATIONS, AND BIOCHEMISTRY OF DEOXYRIBOZYMES.TRENDS IN BIOCHEMICAL SCIENCES. VOL. 41. ISSUE 7. P. 595 -609 66 56% 4
9 JOYCE, GF , (2004) DIRECTED EVOLUTION OF NUCLEIC ACID ENZYMES.ANNUAL REVIEW OF BIOCHEMISTRY. VOL. 73. ISSUE . P. 791 -836 70 60% 282
10 RAZ, MH , HOLLENSTEIN, M , (2015) PROBING THE EFFECT OF MINOR GROOVE INTERACTIONS ON THE CATALYTIC EFFICIENCY OF DNAZYMES 8-17 AND 10-23.MOLECULAR BIOSYSTEMS. VOL. 11. ISSUE 5. P. 1454 -1461 57 67% 3

Classes with closest relation at Level 1


Rank Class id link
1 2916 RIBOZYME//HAMMERHEAD RIBOZYME//CATALYTIC RNA
2 17844 GILEAD IOCB//REVERSIBLE TERMINATOR//LIFE SCI SOLUT GRP
3 4185 GROUP I INTRON//RIBOZYME//SELF SPLICING
4 12082 RIBOSWITCH//CANC UK NUCLE ACID STRUCT GRP//RNA SWITCH
5 293 APTAMER//SELEX//APTASENSOR
6 2094 ORIGINS OF LIFE AND EVOLUTION OF BIOSPHERES//ORIGIN OF LIFE//PREBIOTIC CHEMISTRY
7 6080 MERCURY ION//COLORIMETRIC DETECTION//MERCURYII ION
8 36765 PROGRAM BIOCHEM CHEM//2 SELENOURIDINE TRIPHOSPHATE//3 5 O DIACETYL 5 AMINOMETHYL 2 DEOXYURIDINE
9 24948 HYPERCYCLE//STOCHASTIC CORRECTOR MODEL//PREBIOTIC EVOLUTION
10 10629 GENETIC CODE//CIRCULAR CODE//EQUIPE BIOINFORMAT THEOR

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