Class information for:
Level 1: GIRDIN//GIV//GROWTH FACTOR RECEPTOR TYROSINE KINASE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
33666 122 43.6 91%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
405 3       BACTERIORHODOPSIN//G PROTEIN COUPLED RECEPTOR//G PROTEIN 29641
2998 2             RGS PROTEINS//GIRDIN//RGS 2563
33666 1                   GIRDIN//GIV//GROWTH FACTOR RECEPTOR TYROSINE KINASE 122

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 GIRDIN authKW 9811427 34% 93% 42
2 GIV authKW 1042880 4% 83% 5
3 GROWTH FACTOR RECEPTOR TYROSINE KINASE authKW 819131 5% 55% 6
4 GIRDIN PROTEIN authKW 500583 2% 100% 2
5 MIGRATION PROLIFERATION DICHOTOMY authKW 333721 2% 67% 2
6 GEORGE PALADE S CELLULAR MOL MED address 281574 2% 38% 3
7 ADENYLYL CYCLASE INDEPENDENT authKW 250292 1% 100% 1
8 AKT BINDING PROTEIN authKW 250292 1% 100% 1
9 ANTICATABOLIC ACTIONS authKW 250292 1% 100% 1
10 ASSOCIATED PROJECTS address 250292 1% 100% 1

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Cell Biology 711 39% 0% 48
2 Biochemistry & Molecular Biology 185 34% 0% 42
3 Oncology 180 21% 0% 26
4 Developmental Biology 42 4% 0% 5
5 Biophysics 38 7% 0% 9
6 Pathology 18 4% 0% 5
7 Biology 18 4% 0% 5
8 Peripheral Vascular Diseases 9 3% 0% 4
9 Multidisciplinary Sciences 8 2% 0% 2
10 Neurosciences 5 7% 0% 8

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 GEORGE PALADE S CELLULAR MOL MED 281574 2% 38% 3
2 ASSOCIATED PROJECTS 250292 1% 100% 1
3 CELL BIOL ANATSHOWA KU 250292 1% 100% 1
4 DEPAT OBSTET GYNECOL 250292 1% 100% 1
5 ENDOSCOP DIAGNOST 250292 1% 100% 1
6 GEORGE E PALADE S 250292 1% 100% 1
7 SCIMRB 250292 1% 100% 1
8 TEACHING WESTERN MED 250292 1% 100% 1
9 UM144 250292 1% 100% 1
10 CELL MECHANOSENSING 250290 2% 50% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MOLECULAR BIOLOGY OF THE CELL 1468 6% 0% 7
2 DEVELOPMENTAL CELL 872 2% 0% 3
3 CELL BIOPHYSICS 752 1% 0% 1
4 CELL ADHESION & MIGRATION 424 1% 0% 1
5 ONCOLOGY LETTERS 410 2% 0% 3
6 BREAST CANCER 400 1% 0% 1
7 MOLECULAR MEDICINE REPORTS 366 2% 0% 3
8 CURRENT VASCULAR PHARMACOLOGY 364 1% 0% 1
9 REVIEWS IN THE NEUROSCIENCES 362 1% 0% 1
10 ELIFE 337 2% 0% 2

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 GIRDIN 9811427 34% 93% 42 Search GIRDIN Search GIRDIN
2 GIV 1042880 4% 83% 5 Search GIV Search GIV
3 GROWTH FACTOR RECEPTOR TYROSINE KINASE 819131 5% 55% 6 Search GROWTH+FACTOR+RECEPTOR+TYROSINE+KINASE Search GROWTH+FACTOR+RECEPTOR+TYROSINE+KINASE
4 GIRDIN PROTEIN 500583 2% 100% 2 Search GIRDIN+PROTEIN Search GIRDIN+PROTEIN
5 MIGRATION PROLIFERATION DICHOTOMY 333721 2% 67% 2 Search MIGRATION+PROLIFERATION+DICHOTOMY Search MIGRATION+PROLIFERATION+DICHOTOMY
6 ADENYLYL CYCLASE INDEPENDENT 250292 1% 100% 1 Search ADENYLYL+CYCLASE+INDEPENDENT Search ADENYLYL+CYCLASE+INDEPENDENT
7 AKT BINDING PROTEIN 250292 1% 100% 1 Search AKT+BINDING+PROTEIN Search AKT+BINDING+PROTEIN
8 ANTICATABOLIC ACTIONS 250292 1% 100% 1 Search ANTICATABOLIC+ACTIONS Search ANTICATABOLIC+ACTIONS
9 CARDIAC TISSUE RUPTURE 250292 1% 100% 1 Search CARDIAC+TISSUE+RUPTURE Search CARDIAC+TISSUE+RUPTURE
10 CDK5 GIRDIN 250292 1% 100% 1 Search CDK5+GIRDIN Search CDK5+GIRDIN

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 GHOSH, P , (2015) G PROTEIN COUPLED GROWTH FACTOR RECEPTOR TYROSINE KINASE: NO LONGER AN OXYMORON.CELL CYCLE. VOL. 14. ISSUE 16. P. 2561 -2565 32 89% 0
2 GHOSH, P , (2015) HETEROTRIMERIC G PROTEINS AS EMERGING TARGETS FOR NETWORK BASED THERAPY IN CANCER: END OF A LONG FUTILE CAMPAIGN STRIKING HEADS OF A HYDRA.AGING-US. VOL. 7. ISSUE 7. P. 469 -474 38 72% 1
3 DUNKEL, Y , DIAO, KX , AZNAR, N , SWANSON, L , LIU, L , ZHU, WH , MI, XY , GHOSH, P , (2016) PROGNOSTIC IMPACT OF TOTAL AND TYROSINE PHOSPHORYLATED GIV/GIRDIN IN BREAST CANCERS.FASEB JOURNAL. VOL. 30. ISSUE 11. P. 3702 -3713 32 82% 0
4 AZNAR, N , KALOGRIOPOULOS, N , MIDDE, KK , GHOSH, P , (2016) HETEROTRIMERIC G PROTEIN SIGNALING VIA GIV/GIRDIN: BREAKING THE RULES OF ENGAGEMENT, SPACE, AND TIME.BIOESSAYS. VOL. 38. ISSUE 4. P. 379 -393 46 40% 2
5 PARAG-SHARMA, K , LEYME, A , DIGIACOMO, V , MARIVIN, A , BROSELID, S , GARCIA-MARCOS, M , (2016) MEMBRANE RECRUITMENT OF THE NON-RECEPTOR PROTEIN GIV/GIRDIN (G ALPHA-INTERACTING, VESICLE-ASSOCIATED PROTEIN/GIRDIN) IS SUFFICIENT FOR ACTIVATING HETEROTRIMERIC G PROTEIN SIGNALING.JOURNAL OF BIOLOGICAL CHEMISTRY. VOL. 291. ISSUE 53. P. 27098 -27111 37 54% 0
6 GHOSH, P , (2016) THE UNTAPPED POTENTIAL OF TYROSINE-BASED G PROTEIN SIGNALING.PHARMACOLOGICAL RESEARCH. VOL. 105. ISSUE . P. 99 -107 34 41% 0
7 GHOSH, P , TIE, J , MURANYI, A , SINGH, S , BRUNHOEBER, P , LEITH, K , BOWERMASTER, R , LIAO, ZM , ZHU, YF , LAFLEUR, B , ET AL (2016) GIRDIN (GIV) EXPRESSION AS A PROGNOSTIC MARKER OF RECURRENCE IN MISMATCH REPAIR-PROFICIENT STAGE II COLON CANCER.CLINICAL CANCER RESEARCH. VOL. 22. ISSUE 14. P. 3488 -3498 24 55% 0
8 MA, GS , AZNAR, N , KALOGRIOPOULOS, N , MIDDE, KK , LOPEZ-SANCHEZ, I , SATO, E , DUNKEL, Y , GALLO, RL , GHOSH, P , (2015) THERAPEUTIC EFFECTS OF CELL-PERMEANT PEPTIDES THAT ACTIVATE G PROTEINS DOWNSTREAM OF GROWTH FACTORS.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. VOL. 112. ISSUE 20. P. E2602 -E2610 21 58% 2
9 GARCIA-MARCOS, M , GHOSH, P , FARQUHAR, MG , (2015) GIV/GIRDIN TRANSMITS SIGNALS FROM MULTIPLE RECEPTORS BY TRIGGERING TRIMERIC G PROTEIN ACTIVATION.JOURNAL OF BIOLOGICAL CHEMISTRY. VOL. 290. ISSUE 11. P. 6697 -6704 28 39% 8
10 MIDDE, KK , AZNAR, N , LAEDERICH, MB , MA, GS , KUNKEL, MT , NEWTON, AC , GHOSH, P , (2015) MULTIMODULAR BIOSENSORS REVEAL A NOVEL PLATFORM FOR ACTIVATION OF G PROTEINS BY GROWTH FACTOR RECEPTORS.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. VOL. 112. ISSUE 9. P. E937 -E946 25 48% 1

Classes with closest relation at Level 1


Rank Class id link
1 6385 RGS PROTEINS//RGS//REGULATOR OF G PROTEIN SIGNALING
2 35578 PHLPP1//PHLPP//PHLPP2
3 19622 DISC1//DISRUPTED IN SCHIZOPHRENIA 1//FEZ1
4 6528 PDK1//AKT//AKT2
5 26062 LOE 908//G ALPHA12//VOLTAGE INDEPENDENT CALCIUM CHANNEL
6 756 G PROTEIN//TRANSDUCIN//MED COMM NEUROSCI
7 37469 AML CELL DEATH//ARSENIC TRIOXIDE 1//ATPASE BINDING CASSETTE ABC TRANSPORTERS
8 11431 CRUMBS//SCRIBBLE//ERBIN
9 33345 MIR 101//MIR 26B//MICRORNA 101
10 28689 UHRF1//ICBP90//UHRF2

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