Class information for:
Level 2: RGS PROTEINS//GIRDIN//RGS

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
2998 2563 46.6 93%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
405 3       BACTERIORHODOPSIN//G PROTEIN COUPLED RECEPTOR//G PROTEIN 29641
2998 2             RGS PROTEINS//GIRDIN//RGS 2563
6385 1                   RGS PROTEINS//RGS//REGULATOR OF G PROTEIN SIGNALING 1491
16892 1                   GENISTEIN INHIBITION//TYROSINE KINASE//ANGIOTENSIN II 629
26062 1                   LOE 908//G ALPHA12//VOLTAGE INDEPENDENT CALCIUM CHANNEL 264
33666 1                   GIRDIN//GIV//GROWTH FACTOR RECEPTOR TYROSINE KINASE 122
37469 1                   AML CELL DEATH//ARSENIC TRIOXIDE 1//ATPASE BINDING CASSETTE ABC TRANSPORTERS 57

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 RGS PROTEINS authKW 914034 4% 71% 108
2 GIRDIN authKW 489451 2% 96% 43
3 RGS authKW 456913 2% 63% 61
4 REGULATOR OF G PROTEIN SIGNALING authKW 447336 2% 72% 52
5 RGS2 authKW 379727 2% 74% 43
6 RGS4 authKW 344448 2% 69% 42
7 REGULATORS OF G PROTEIN SIGNALING authKW 248839 1% 67% 31
8 MOL SIGNAL TRANSDUCT SECT address 196024 1% 69% 24
9 RGS5 authKW 156474 1% 77% 17
10 G PROTEIN authKW 146516 10% 5% 262

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Biochemistry & Molecular Biology 5959 41% 0% 1059
2 Cell Biology 3748 21% 0% 535
3 Pharmacology & Pharmacy 1070 14% 0% 364
4 Peripheral Vascular Diseases 994 6% 0% 166
5 Neurosciences 828 13% 0% 328
6 Physiology 759 7% 0% 176
7 Biophysics 461 6% 0% 152
8 Cardiac & Cardiovascular System 270 5% 0% 137
9 Hematology 170 3% 0% 85
10 Biochemical Research Methods 148 4% 0% 90

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MOL SIGNAL TRANSDUCT SECT 196024 1% 69% 24
2 B CELL MOL IMMUNOL SECT 116939 1% 55% 18
3 PHYSIOL HEART STROKE 49632 0% 83% 5
4 CELL MOL IMMUNOL SECT B 41940 0% 39% 9
5 CELL MOL BIOL SECT B 35736 0% 100% 3
6 ROLLINS G205 35736 0% 100% 3
7 CENT NERVOUS SYST DISCOVERY 33085 0% 56% 5
8 RICHARD LEWAR EXCELLENCE CARDIOVASC 29775 0% 50% 5
9 CANC SIGNALING EXPT THER EUT PROGRAM 26801 0% 75% 3
10 UNC NEUROSCI 24214 1% 12% 17

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CELLULAR SIGNALLING 10093 2% 1% 61
2 JOURNAL OF BIOLOGICAL CHEMISTRY 8629 13% 0% 337
3 PROGRESS IN MOLECULAR BIOLOGY AND TRANSLATIONAL SCIENCE 7859 1% 3% 21
4 MOLECULAR PHARMACOLOGY 5713 3% 1% 69
5 METHODS IN ENZYMOLOGY 2623 2% 0% 61
6 AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 1751 1% 0% 33
7 CIRCULATION RESEARCH 1469 1% 0% 36
8 NEUROSIGNALS 1035 0% 2% 5
9 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 1031 3% 0% 81
10 HYPERTENSION 882 1% 0% 30

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 RGS PROTEINS 914034 4% 71% 108 Search RGS+PROTEINS Search RGS+PROTEINS
2 GIRDIN 489451 2% 96% 43 Search GIRDIN Search GIRDIN
3 RGS 456913 2% 63% 61 Search RGS Search RGS
4 REGULATOR OF G PROTEIN SIGNALING 447336 2% 72% 52 Search REGULATOR+OF+G+PROTEIN+SIGNALING Search REGULATOR+OF+G+PROTEIN+SIGNALING
5 RGS2 379727 2% 74% 43 Search RGS2 Search RGS2
6 RGS4 344448 2% 69% 42 Search RGS4 Search RGS4
7 REGULATORS OF G PROTEIN SIGNALING 248839 1% 67% 31 Search REGULATORS+OF+G+PROTEIN+SIGNALING Search REGULATORS+OF+G+PROTEIN+SIGNALING
8 RGS5 156474 1% 77% 17 Search RGS5 Search RGS5
9 G PROTEIN 146516 10% 5% 262 Search G+PROTEIN Search G+PROTEIN
10 RGS10 134206 1% 87% 13 Search RGS10 Search RGS10

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 GERBER, KJ , SQUIRES, KE , HEPLER, JR , (2016) ROLES FOR REGULATOR OF G PROTEIN SIGNALING PROTEINS IN SYNAPTIC SIGNALING AND PLASTICITY.MOLECULAR PHARMACOLOGY. VOL. 89. ISSUE 2. P. 273 -286 144 77% 5
2 KACH, J , SETHAKORN, N , DULIN, NO , (2012) A FINER TUNING OF G-PROTEIN SIGNALING THROUGH REGULATED CONTROL OF RGS PROTEINS.AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY. VOL. 303. ISSUE 1. P. H19-H35 167 84% 21
3 SJOGREN, B , BLAZER, LL , NEUBIG, RR , (2010) REGULATORS OF G PROTEIN SIGNALING PROTEINS AS TARGETS FOR DRUG DISCOVERY.MEMBRANE PROTEINS AS DRUG TARGETS. VOL. 91. ISSUE . P. 81 -119 139 85% 39
4 BANSAL, G , DRUEY, KM , XIE, Z , (2007) R4 RGS PROTEINS: REGULATION OF G-PROTEIN SIGNALING AND BEYOND.PHARMACOLOGY & THERAPEUTICS. VOL. 116. ISSUE 3. P. 473-495 147 77% 90
5 HOLLINGER, S , HEPLER, JR , (2002) CELLULAR REGULATION OF RGS PROTEINS: MODULATORS AND INTEGRATORS OF G PROTEIN SIGNALING.PHARMACOLOGICAL REVIEWS. VOL. 54. ISSUE 3. P. 527-559 128 69% 466
6 WILLARS, GB , (2006) MAMMALIAN RGS PROTEINS: MULTIFUNCTIONAL REGULATORS OF CELLULAR SIGNALLING.SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY. VOL. 17. ISSUE 3. P. 363-376 136 78% 94
7 SJOGREN, B , (2017) THE EVOLUTION OF REGULATORS OF G PROTEIN SIGNALLING PROTEINS AS DRUG TARGETS-20 YEARS IN THE MAKING: IUPHAR REVIEW 21.BRITISH JOURNAL OF PHARMACOLOGY. VOL. 174. ISSUE 6. P. 427 -437 110 84% 0
8 ZHANG, P , MENDE, U , (2011) REGULATORS OF G-PROTEIN SIGNALING IN THE HEART AND THEIR POTENTIAL AS THERAPEUTIC TARGETS.CIRCULATION RESEARCH. VOL. 109. ISSUE 3. P. 320 -333 112 84% 20
9 XIE, GX , PALMER, PP , (2007) HOW REGULATORS OF G PROTEIN SIGNALING ACHIEVE SELECTIVE REGULATION.JOURNAL OF MOLECULAR BIOLOGY. VOL. 366. ISSUE 2. P. 349-365 123 78% 61
10 KIMPLE, AJ , BOSCH, DE , GIGUERE, PM , SIDEROVSKI, DP , (2011) REGULATORS OF G-PROTEIN SIGNALING AND THEIR G ALPHA SUBSTRATES: PROMISES AND CHALLENGES IN THEIR USE AS DRUG DISCOVERY TARGETS.PHARMACOLOGICAL REVIEWS. VOL. 63. ISSUE 3. P. 728 -749 129 54% 86

Classes with closest relation at Level 2


Rank Class id link
1 1079 BETA3 ADRENOCEPTOR//ADENYLYL CYCLASE//G PROTEIN
2 705 G PROTEIN COUPLED RECEPTOR//GPCR//RHODOPSIN
3 2742 LYSOPHOSPHATIDIC ACID//AUTOTAXIN//DIADENOSINE POLYPHOSPHATES
4 2254 PHOSPHOLIPASE D//DIACYLGLYCEROL KINASE//PHOSPHATIDIC ACID
5 1195 JNK//ERK5//MAP KINASE
6 536 X LINKED AGAMMAGLOBULINEMIA//BTK//SH2 DOMAIN
7 2517 PROTEASE ACTIVATED RECEPTOR//THROMBIN//THROMBIN RECEPTOR
8 2803 GAP 43//PALMITOYLATION//MARCKS
9 1764 STIM1//ORAI1//STORE OPERATED CALCIUM ENTRY
10 2204 MIBEFRADIL//T TYPE CALCIUM CHANNEL//CALCIUM CHANNELS

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