Class information for:
Level 2: PROTEASE ACTIVATED RECEPTOR//THROMBIN//THROMBIN RECEPTOR

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
2517 3827 45.1 88%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
111 3       THROMBOSIS RESEARCH//THROMBOSIS AND HAEMOSTASIS//HEMATOLOGY 71244
2517 2             PROTEASE ACTIVATED RECEPTOR//THROMBIN//THROMBIN RECEPTOR 3827
2064 1                   PROTEASE ACTIVATED RECEPTOR//PROTEASE ACTIVATED RECEPTOR 2//THROMBIN RECEPTOR 2368
13770 1                   NEUROSERPIN//TISSUE PLASMINOGEN ACTIVATOR//TISSUE TYPE PLASMINOGEN ACTIVATOR 814
16609 1                   PROTEASE NEXIN 1//THROMBIN//PROTEASE NEXIN I 645

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PROTEASE ACTIVATED RECEPTOR authKW 1325226 7% 61% 271
2 THROMBIN authKW 830517 17% 16% 643
3 THROMBIN RECEPTOR authKW 618299 3% 64% 122
4 PROTEASE ACTIVATED RECEPTOR 2 authKW 480587 3% 56% 107
5 PROTEINASE ACTIVATED RECEPTOR authKW 411238 2% 66% 78
6 PAR2 authKW 341143 2% 70% 61
7 PROTEINASE ACTIVATED RECEPTOR 2 authKW 298186 1% 69% 54
8 PAR 2 authKW 211905 2% 45% 59
9 PROTEASE ACTIVATED RECEPTOR 1 authKW 200469 1% 47% 54
10 PROTEASE NEXIN 1 authKW 180790 1% 67% 34

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Hematology 5565 12% 0% 469
2 Neurosciences 4629 22% 0% 841
3 Peripheral Vascular Diseases 4329 10% 0% 401
4 Cell Biology 2070 14% 0% 521
5 Biochemistry & Molecular Biology 2033 23% 0% 866
6 Pharmacology & Pharmacy 1330 13% 0% 506
7 Physiology 812 6% 0% 229
8 Medicine, Research & Experimental 482 5% 0% 205
9 Clinical Neurology 171 5% 0% 174
10 Chemistry, Medicinal 157 3% 0% 103

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 DIABET ENDOCRINE GRP 60449 0% 63% 12
2 MUCOSAL INFLAMMAT GRP 49662 1% 23% 27
3 ENDOCRINE GRP 42345 0% 30% 18
4 DAIICHI 36460 0% 57% 8
5 J SAGOL NEUROSCI 36248 0% 45% 10
6 NEUROBIOL 151 35894 0% 75% 6
7 CANADIAN HLTH PROTEINASES INFLAMMAT NE 31908 0% 100% 4
8 KEY IMMUNOPHARMACOL GUANGDONG PROVINCE 31908 0% 100% 4
9 KEY IMMUNOPHARMACOL GUANGDONG PROV 28713 0% 60% 6
10 GRP PHARMACOL HEMOSTASEOL 28487 0% 71% 5

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 THROMBOSIS AND HAEMOSTASIS 5254 2% 1% 82
2 BRITISH JOURNAL OF PHARMACOLOGY 4171 3% 1% 98
3 SEMINARS IN THROMBOSIS AND HEMOSTASIS 3231 1% 1% 33
4 JOURNAL OF THROMBOSIS AND HAEMOSTASIS 3195 1% 1% 40
5 JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM 2445 1% 1% 41
6 JOURNAL OF CELLULAR PHYSIOLOGY 2058 1% 1% 52
7 ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 1812 1% 1% 42
8 JOURNAL OF BIOLOGICAL CHEMISTRY 1810 5% 0% 200
9 JOURNAL OF NEUROCHEMISTRY 1760 2% 0% 70
10 JOURNAL OF NEUROSCIENCE RESEARCH 1687 1% 1% 44

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 PROTEASE ACTIVATED RECEPTOR 1325226 7% 61% 271 Search PROTEASE+ACTIVATED+RECEPTOR Search PROTEASE+ACTIVATED+RECEPTOR
2 THROMBIN 830517 17% 16% 643 Search THROMBIN Search THROMBIN
3 THROMBIN RECEPTOR 618299 3% 64% 122 Search THROMBIN+RECEPTOR Search THROMBIN+RECEPTOR
4 PROTEASE ACTIVATED RECEPTOR 2 480587 3% 56% 107 Search PROTEASE+ACTIVATED+RECEPTOR+2 Search PROTEASE+ACTIVATED+RECEPTOR+2
5 PROTEINASE ACTIVATED RECEPTOR 411238 2% 66% 78 Search PROTEINASE+ACTIVATED+RECEPTOR Search PROTEINASE+ACTIVATED+RECEPTOR
6 PAR2 341143 2% 70% 61 Search PAR2 Search PAR2
7 PROTEINASE ACTIVATED RECEPTOR 2 298186 1% 69% 54 Search PROTEINASE+ACTIVATED+RECEPTOR+2 Search PROTEINASE+ACTIVATED+RECEPTOR+2
8 PAR 2 211905 2% 45% 59 Search PAR+2 Search PAR+2
9 PROTEASE ACTIVATED RECEPTOR 1 200469 1% 47% 54 Search PROTEASE+ACTIVATED+RECEPTOR+1 Search PROTEASE+ACTIVATED+RECEPTOR+1
10 PROTEASE NEXIN 1 180790 1% 67% 34 Search PROTEASE+NEXIN+1 Search PROTEASE+NEXIN+1

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 STEINHOFF, M , BUDDENKOTTE, J , SHPACOVITCH, V , RATTENHOLL, A , MOORMANN, C , VERGNOLLE, N , LUGER, TA , HOLLENBERG, MD , (2005) PROTEINASE-ACTIVATED RECEPTORS: TRANSDUCERS OF PROTEINASE-MEDIATED SIGNALING IN INFLAMMATION AND IMMUNE RESPONSE.ENDOCRINE REVIEWS. VOL. 26. ISSUE 1. P. 1-43 351 79% 331
2 ADAMS, MN , RAMACHANDRAN, R , YAU, MK , SUEN, JY , FAIRLIE, DP , HOLLENBERG, MD , HOOPER, JD , (2011) STRUCTURE, FUNCTION AND PATHOPHYSIOLOGY OF PROTEASE ACTIVATED RECEPTORS.PHARMACOLOGY & THERAPEUTICS. VOL. 130. ISSUE 3. P. 248 -282 344 70% 106
3 MACFARLANE, SR , SEATTER, MJ , KANKE, T , HUNTER, GD , PLEVIN, R , (2001) PROTEINASE-ACTIVATED RECEPTORS.PHARMACOLOGICAL REVIEWS. VOL. 53. ISSUE 2. P. 245 -282 277 69% 836
4 OSSOVSKAYA, VS , BUNNETT, NW , (2004) PROTEASE-ACTIVATED RECEPTORS: CONTRIBUTION TO PHYSIOLOGY AND DISEASE.PHYSIOLOGICAL REVIEWS. VOL. 84. ISSUE 2. P. 579-621 235 76% 643
5 RAMACHANDRAN, R , HOLLENBERG, MD , (2008) PROTEINASES AND SIGNALLING: PATHOPHYSIOLOGICAL AND THERAPEUTIC IMPLICATIONS VIA PARS AND MORE.BRITISH JOURNAL OF PHARMACOLOGY. VOL. 153. ISSUE . P. S263 -S282 219 80% 182
6 GUTIERREZ-RODRIGUEZ, M , HERRANZ, R , (2015) FROM MULTIPLE PAR1 RECEPTOR/PROTEIN INTERACTIONS TO THEIR MULTIPLE THERAPEUTIC IMPLICATIONS.CURRENT TOPICS IN MEDICINAL CHEMISTRY. VOL. 15. ISSUE 20. P. 2080 -2114 270 66% 3
7 RAMACHANDRAN, R , NOORBAKHSH, F , DEFEA, K , HOLLENBERG, MD , (2012) TARGETING PROTEINASE-ACTIVATED RECEPTORS: THERAPEUTIC POTENTIAL AND CHALLENGES.NATURE REVIEWS DRUG DISCOVERY. VOL. 11. ISSUE 1. P. 69 -86 161 75% 111
8 BARRY, GD , LE, GT , FAIRLIE, DP , (2006) AGONISTS AND ANTAGONISTS OF PROTEASE ACTIVATED RECEPTORS (PARS).CURRENT MEDICINAL CHEMISTRY. VOL. 13. ISSUE 3. P. 243-265 161 88% 49
9 LEE, H , HAMILTON, JR , (2012) PHYSIOLOGY, PHARMACOLOGY, AND THERAPEUTIC POTENTIAL OF PROTEASE-ACTIVATED RECEPTORS IN VASCULAR DISEASE.PHARMACOLOGY & THERAPEUTICS. VOL. 134. ISSUE 2. P. 246 -259 150 77% 19
10 YAU, MK , LIU, LG , FAIRLIE, DP , (2013) TOWARD DRUGS FOR PROTEASE-ACTIVATED RECEPTOR 2 (PAR2).JOURNAL OF MEDICINAL CHEMISTRY. VOL. 56. ISSUE 19. P. 7477-7497 142 76% 16

Classes with closest relation at Level 2


Rank Class id link
1 2572 UROKINASE RECEPTOR//UPAR//UPA
2 637 TISSUE FACTOR//THROMBOMODULIN//PROTEIN C
3 2272 HEPARIN INDUCED THROMBOCYTOPENIA//ARGATROBAN//HIRUDIN
4 3099 ALPHA 2 MACROGLOBULIN//LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN//LRP1
5 697 MEAN PLATELET VOLUME//PLATELETS//HEMATOLOGY
6 2447 DYSFIBRINOGENEMIA//AFIBRINOGENEMIA//FIBRINOGEN
7 2998 RGS PROTEINS//GIRDIN//RGS
8 707 MATRIX METALLOPROTEINASE//METALLOPROTEINASES//MT1 MMP
9 1214 FACTOR XIII//TRANSGLUTAMINASE//TRANSGLUTAMINASE 2
10 1157 FIBRINOLYSIS//PLASMINOGEN ACTIVATOR INHIBITOR 1//PAI 1

Go to start page