Class information for:
Level 2: G PROTEIN COUPLED RECEPTOR//GPCR//RHODOPSIN

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
705 12950 45.3 80%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
405 3       BACTERIORHODOPSIN//G PROTEIN COUPLED RECEPTOR//G PROTEIN 29641
705 2             G PROTEIN COUPLED RECEPTOR//GPCR//RHODOPSIN 12950
1278 1                   MUSCARINIC RECEPTOR SUBTYPES//MUSCARINIC RECEPTORS//PIRENZEPINE 2747
2285 1                   G PROTEIN COUPLED RECEPTOR KINASE//ARRESTIN//BETA ARRESTIN 2296
3579 1                   RHODOPSIN//RETINAL//BATHORHODOPSIN 1954
4196 1                   G PROTEIN COUPLED RECEPTOR//GPCR//MEMBRANE PROT STRUCT FUNCT UNIT 1830
9142 1                   RECEPTOR MOSAICS//HETEROMER//RECEPTOR RECEPTOR INTERACTIONS 1184
10380 1                   XANOMELINE//M 1//ALCURONIUM 1069
15795 1                   AMPHIPOLS//UMR 7099//MEMBRANE PROTEIN 691
26108 1                   BIOCHEM TECHNOL SCI TECHNOL//GPR35//RESONANT WAVEGUIDE GRATING BIOSENSOR 263
26532 1                   AGONIST AFFINITY//ANTAGONIST DISSOCIATION CONSTANTS//IRREVERSIBLE RECEPTOR INACTIVATION METHOD 252
28909 1                   GPRC5A//GPR12//GPR139 197
30621 1                   SEROTONIN1A RECEPTOR//BOVINE HIPPOCAMPUS//P MPPF 166
30920 1                   PHARMACOPERONE//ER EXPORT MOTIF//EXPORT TRAFFICKING 161
32378 1                   FLUORESCENT LIGANDS//1012 S//ALEXA FLUOR R 647 140

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 G PROTEIN COUPLED RECEPTOR authKW 420498 7% 19% 925
2 GPCR authKW 180223 3% 20% 393
3 RHODOPSIN authKW 178936 2% 27% 277
4 MUSCARINIC RECEPTORS authKW 167216 3% 17% 429
5 ARRESTIN authKW 163854 1% 42% 165
6 G PROTEIN COUPLED RECEPTOR KINASE authKW 157732 1% 59% 114
7 BETA ARRESTIN authKW 127262 1% 40% 134
8 MUSCARINIC RECEPTOR SUBTYPES authKW 86488 1% 44% 84
9 XANOMELINE authKW 72143 0% 88% 35
10 GRK2 authKW 65359 0% 58% 48

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Biochemistry & Molecular Biology 28347 40% 0% 5213
2 Pharmacology & Pharmacy 26585 28% 0% 3605
3 Biophysics 6847 9% 0% 1203
4 Chemistry, Medicinal 6758 7% 0% 965
5 Cell Biology 3083 10% 0% 1272
6 Neurosciences 2101 10% 0% 1287
7 Biochemical Research Methods 1454 4% 0% 581
8 Medicine, Research & Experimental 218 3% 0% 361
9 Physiology 131 2% 0% 282
10 Chemistry, Multidisciplinary 99 5% 0% 676

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOCHEM TECHNOL SCI TECHNOL 55397 0% 87% 27
2 MOL PHARMACOL GRP 52107 1% 24% 93
3 ZENTRUM BIOPHYS BIOINFORMAT 36771 0% 71% 22
4 UNITAT BIOESTADIST 36081 0% 28% 54
5 MED COMPUTAC 35946 0% 36% 43
6 MEMBRANE PROT STRUCT FUNCT UNIT 33129 0% 94% 15
7 UMR 7099 32982 0% 37% 38
8 DRUG DISCOVERY BIOL 28225 0% 28% 43
9 GEORGE ZALLIE FAMILY CARDIOVASC GENE THER 27792 0% 54% 22
10 MED PHYS BIOPHYS CC2 23464 0% 59% 17

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 MOLECULAR PHARMACOLOGY 63972 4% 5% 517
2 TRENDS IN PHARMACOLOGICAL SCIENCES 31447 2% 6% 214
3 JOURNAL OF BIOLOGICAL CHEMISTRY 14404 8% 1% 1005
4 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 12641 3% 2% 343
5 BRITISH JOURNAL OF PHARMACOLOGY 12621 2% 2% 314
6 JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION 10247 0% 8% 52
7 BIOCHEMISTRY 10003 4% 1% 493
8 EUROPEAN JOURNAL OF PHARMACOLOGY 8616 3% 1% 330
9 RECEPTORS & CHANNELS 7626 0% 10% 32
10 JOURNAL OF MEDICINAL CHEMISTRY 6185 2% 1% 245

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 G PROTEIN COUPLED RECEPTOR 420498 7% 19% 925 Search G+PROTEIN+COUPLED+RECEPTOR Search G+PROTEIN+COUPLED+RECEPTOR
2 GPCR 180223 3% 20% 393 Search GPCR Search GPCR
3 RHODOPSIN 178936 2% 27% 277 Search RHODOPSIN Search RHODOPSIN
4 MUSCARINIC RECEPTORS 167216 3% 17% 429 Search MUSCARINIC+RECEPTORS Search MUSCARINIC+RECEPTORS
5 ARRESTIN 163854 1% 42% 165 Search ARRESTIN Search ARRESTIN
6 G PROTEIN COUPLED RECEPTOR KINASE 157732 1% 59% 114 Search G+PROTEIN+COUPLED+RECEPTOR+KINASE Search G+PROTEIN+COUPLED+RECEPTOR+KINASE
7 BETA ARRESTIN 127262 1% 40% 134 Search BETA+ARRESTIN Search BETA+ARRESTIN
8 MUSCARINIC RECEPTOR SUBTYPES 86488 1% 44% 84 Search MUSCARINIC+RECEPTOR+SUBTYPES Search MUSCARINIC+RECEPTOR+SUBTYPES
9 XANOMELINE 72143 0% 88% 35 Search XANOMELINE Search XANOMELINE
10 GRK2 65359 0% 58% 48 Search GRK2 Search GRK2

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 FANELLI, F , DE BENEDETTI, PG , (2011) UPDATE 1 OF: COMPUTATIONAL MODELING APPROACHES TO STRUCTURE-FUNCTION ANALYSIS OF G PROTEIN-COUPLED RECEPTORS.CHEMICAL REVIEWS. VOL. 111. ISSUE . P. PR438 -PR535 665 56% 38
2 SATO, PY , CHUPRUN, JK , SCHWARTZ, M , KOCH, WJ , (2015) THE EVOLVING IMPACT OF G PROTEIN-COUPLED RECEPTOR KINASES IN CARDIAC HEALTH AND DISEASE.PHYSIOLOGICAL REVIEWS. VOL. 95. ISSUE 2. P. 377 -404 210 78% 12
3 KATRITCH, V , CHEREZOV, V , STEVENS, RC , (2013) STRUCTURE-FUNCTION OF THE G PROTEIN-COUPLED RECEPTOR SUPERFAMILY.ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 53, 2013. VOL. 53. ISSUE . P. 531-556 103 90% 289
4 GUREVICH, EV , TESMER, JJG , MUSHEGIAN, A , GUREVICH, VV , (2012) G PROTEIN-COUPLED RECEPTOR KINASES: MORE THAN JUST KINASES AND NOT ONLY FOR GPCRS.PHARMACOLOGY & THERAPEUTICS. VOL. 133. ISSUE 1. P. 40 -69 235 56% 92
5 KENAKIN, T , MILLER, LJ , (2010) SEVEN TRANSMEMBRANE RECEPTORS AS SHAPESHIFTING PROTEINS: THE IMPACT OF ALLOSTERIC MODULATION AND FUNCTIONAL SELECTIVITY ON NEW DRUG DISCOVERY.PHARMACOLOGICAL REVIEWS. VOL. 62. ISSUE 2. P. 265 -304 234 46% 297
6 LOHSE, MJ , NUBER, S , HOFFMANN, C , (2012) FLUORESCENCE/BIOLUMINESCENCE RESONANCE ENERGY TRANSFER TECHNIQUES TO STUDY G-PROTEIN-COUPLED RECEPTOR ACTIVATION AND SIGNALING.PHARMACOLOGICAL REVIEWS. VOL. 64. ISSUE 2. P. 299 -336 247 51% 96
7 LATORRACA, NR , VENKATAKRISHNAN, AJ , DROR, RO , (2017) GPCR DYNAMICS: STRUCTURES IN MOTION.CHEMICAL REVIEWS. VOL. 117. ISSUE 1. P. 139 -155 119 78% 1
8 VENKATAKRISHNAN, AJ , DEUPI, X , LEBON, G , TATE, CG , SCHERTLER, GF , BABU, MM , (2013) MOLECULAR SIGNATURES OF G-PROTEIN-COUPLED RECEPTORS.NATURE. VOL. 494. ISSUE 7436. P. 185-194 79 83% 412
9 FANELLI, F , DE BENEDETTI, PG , (2005) COMPUTATIONAL MODELING APPROACHES TO STRUCTURE-FUNCTION ANALYSIS OF G PROTEIN-COUPLED RECEPTORS.CHEMICAL REVIEWS. VOL. 105. ISSUE 9. P. 3297 -3351 310 52% 119
10 FERGUSON, SSG , (2001) EVOLVING CONCEPTS IN G PROTEIN-COUPLED RECEPTOR ENDOCYTOSIS: THE ROLE IN RECEPTOR DESENSITIZATION AND SIGNALING.PHARMACOLOGICAL REVIEWS. VOL. 53. ISSUE 1. P. 1 -24 152 61% 1165

Classes with closest relation at Level 2


Rank Class id link
1 2396 BACTERIORHODOPSIN//PURPLE MEMBRANE//PHOTOCYCLE
2 1079 BETA3 ADRENOCEPTOR//ADENYLYL CYCLASE//G PROTEIN
3 2998 RGS PROTEINS//GIRDIN//RGS
4 2259 METABOTROPIC GLUTAMATE RECEPTOR//MGLUR5//MPEP
5 266 RETINITIS PIGMENTOSA//OPHTHALMOLOGY//RETINA
6 1269 JOURNAL OF CHEMICAL INFORMATION AND MODELING//LIFE SCI INFORMAT//B IT
7 1265 NICOTINE//NICOTINIC RECEPTORS//NICOTINIC ACETYLCHOLINE RECEPTOR
8 2008 FSH RECEPTOR//FOLLICLE STIMULATING HORMONE RECEPTOR//HUMAN CHORIONIC GONADOTROPIN
9 409 ADENOSINE//ADENOSINE RECEPTORS//ATP
10 1522 HISTAMINE//HISTAMINE H 3 RECEPTOR//THIOPERAMIDE

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