Class information for:
Level 1: PHARMACOPERONE//ER EXPORT MOTIF//EXPORT TRAFFICKING

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
30920 161 54.6 94%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
405 3       BACTERIORHODOPSIN//G PROTEIN COUPLED RECEPTOR//G PROTEIN 29641
705 2             G PROTEIN COUPLED RECEPTOR//GPCR//RHODOPSIN 12950
30920 1                   PHARMACOPERONE//ER EXPORT MOTIF//EXPORT TRAFFICKING 161

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PHARMACOPERONE authKW 2065197 9% 78% 14
2 ER EXPORT MOTIF authKW 568985 2% 100% 3
3 EXPORT TRAFFICKING authKW 568985 2% 100% 3
4 CELL BIOL HUMAN DEV address 379323 1% 100% 2
5 EXPORT MOTIF authKW 379323 1% 100% 2
6 SUPPORT NETWORK address 213365 2% 38% 3
7 PHARMACOLOGICAL CHAPERONE authKW 210717 6% 11% 10
8 UNIT REPROD MED address 204882 7% 10% 11
9 CALNEXINE authKW 189662 1% 100% 1
10 CALRETICULINE authKW 189662 1% 100% 1

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Endocrinology & Metabolism 510 22% 0% 36
2 Biochemistry & Molecular Biology 435 44% 0% 71
3 Cell Biology 310 24% 0% 38
4 Pharmacology & Pharmacy 153 20% 0% 32
5 Biochemical Research Methods 76 8% 0% 13
6 Information Science & Library Science 17 2% 0% 3
7 Biophysics 13 4% 0% 7
8 Biology 3 2% 0% 3
9 Substance Abuse 1 1% 0% 1
10 Materials Science, Biomaterials 1 1% 0% 1

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CELL BIOL HUMAN DEV 379323 1% 100% 2
2 SUPPORT NETWORK 213365 2% 38% 3
3 UNIT REPROD MED 204882 7% 10% 11
4 CNRS UMR8104 ENDOCRINOL 189662 1% 100% 1
5 CNRS UMR8104 GENET DEV PATHOL MOL 189662 1% 100% 1
6 KTLD SECT 22 189662 1% 100% 1
7 MRCUNIT MOL REPROD ENDOCRINOL 189662 1% 100% 1
8 PHYSIOL PHARMACOL CELL DEV BIOL 189662 1% 100% 1
9 REPROD DEV SCI NEUROSCI 189662 1% 100% 1
10 NEUROSCI REPROD SCI 121921 2% 21% 3

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 TRAFFIC 3550 4% 0% 6
2 MOLECULAR PHARMACOLOGY 2345 7% 0% 11
3 CELLULAR SIGNALLING 2127 4% 0% 7
4 MOLECULAR ENDOCRINOLOGY 1646 4% 0% 7
5 TRENDS IN PHARMACOLOGICAL SCIENCES 1390 3% 0% 5
6 MOLECULAR AND CELLULAR ENDOCRINOLOGY 1067 4% 0% 7
7 JOURNAL OF BIOLOGICAL CHEMISTRY 966 17% 0% 28
8 METHODS IN ENZYMOLOGY 933 6% 0% 9
9 PHARMACOLOGICAL RESEARCH 743 2% 0% 4
10 ENDOCRINE REVIEWS 730 1% 0% 2

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 PHARMACOPERONE 2065197 9% 78% 14 Search PHARMACOPERONE Search PHARMACOPERONE
2 ER EXPORT MOTIF 568985 2% 100% 3 Search ER+EXPORT+MOTIF Search ER+EXPORT+MOTIF
3 EXPORT TRAFFICKING 568985 2% 100% 3 Search EXPORT+TRAFFICKING Search EXPORT+TRAFFICKING
4 EXPORT MOTIF 379323 1% 100% 2 Search EXPORT+MOTIF Search EXPORT+MOTIF
5 PHARMACOLOGICAL CHAPERONE 210717 6% 11% 10 Search PHARMACOLOGICAL+CHAPERONE Search PHARMACOLOGICAL+CHAPERONE
6 CALNEXINE 189662 1% 100% 1 Search CALNEXINE Search CALNEXINE
7 CALRETICULINE 189662 1% 100% 1 Search CALRETICULINE Search CALRETICULINE
8 ENHANCED RECEPTOR EXPRESSION 189662 1% 100% 1 Search ENHANCED+RECEPTOR+EXPRESSION Search ENHANCED+RECEPTOR+EXPRESSION
9 ER PROTEIN RETENTION 189662 1% 100% 1 Search ER+PROTEIN+RETENTION Search ER+PROTEIN+RETENTION
10 G286A 189662 1% 100% 1 Search G286A Search G286A

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 FAN, Y , LI, CM , GUO, JH , HU, G , WU, GY , (2012) A SINGLE LYS RESIDUE ON THE FIRST INTRACELLULAR LOOP MODULATES THE ENDOPLASMIC RETICULUM EXPORT AND CELL-SURFACE EXPRESSION OF ALPHA(2A)-ADRENERGIC RECEPTOR.PLOS ONE. VOL. 7. ISSUE 12. P. - 29 57% 2
2 JANOVICK, JA , POGOZHEVA, ID , MOSBERG, HI , CORNEA, A , CONN, PM , (2012) RESCUE OF MISROUTED GNRHR MUTANTS REVEALS ITS CONSTITUTIVE ACTIVITY.MOLECULAR ENDOCRINOLOGY. VOL. 26. ISSUE 7. P. 1179-1188 27 52% 1
3 JANOVICK, JA , CONN, PM , (2010) USE OF PHARMACOPERONES TO REVEAL GPCR STRUCTURAL CHANGES ASSOCIATED WITH CONSTITUTIVE ACTIVATION AND TRAFFICKING.METHODS IN ENZYMOLOGY, VOLUME 485: CONSTITUTIVE ACTIVITY IN RECEPTORS AND OTHER PROTEINS, PART B. VOL. 485. ISSUE . P. 277-292 18 72% 2
4 JANOVICK, JA , STEWART, MD , JACOB, D , MARTIN, LD , DENG, JM , STEWART, CA , WANG, Y , CORNEA, A , CHAVALI, L , LOPEZ, S , ET AL (2013) RESTORATION OF TESTIS FUNCTION IN HYPOGONADOTROPIC HYPOGONADAL MICE HARBORING A MISFOLDED GNRHR MUTANT BY PHARMACOPERONE DRUG THERAPY.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. VOL. 110. ISSUE 52. P. 21030-21035 17 63% 14
5 JANOVICK, JA , CONN, PM , (2010) SALT BRIDGE INTEGRATES GPCR ACTIVATION WITH PROTEIN TRAFFICKING.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. VOL. 107. ISSUE 9. P. 4454-4458 18 64% 9
6 CONN, PM , ULLOA-AGUIRRE, A , (2010) TRAFFICKING OF G-PROTEIN-COUPLED RECEPTORS TO THE PLASMA MEMBRANE: INSIGHTS FOR PHARMACOPERONE DRUGS.TRENDS IN ENDOCRINOLOGY AND METABOLISM. VOL. 21. ISSUE 3. P. 190-197 24 41% 27
7 JANOVICK, JA , POGOZHEVA, ID , MOSBERG, HI , CONN, PM , (2011) SALT BRIDGES OVERLAPPING THE GONADOTROPIN-RELEASING HORMONE RECEPTOR AGONIST BINDING SITE REVEAL A COINCIDENCE DETECTOR FOR G PROTEIN-COUPLED RECEPTOR ACTIVATION.JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. VOL. 338. ISSUE 2. P. 430-442 19 54% 3
8 CABRERA-WROOMAN, A , JANOVICK, JA , CONN, PM , (2013) SPECIES SEQUENCE DIFFERENCES DETERMINE THE INTERACTION OF GNRH RECEPTOR WITH THE CELLULAR QUALITY CONTROL SYSTEM.MOLECULAR AND CELLULAR ENDOCRINOLOGY. VOL. 381. ISSUE 1-2. P. 1-7 21 46% 1
9 CONN, PM , SMITH, E , SPICER, T , CHASE, P , SCAMPAVIA, L , JANOVICK, JA , (2014) A PHENOTYPIC HIGH THROUGHPUT SCREENING ASSAY FOR THE IDENTIFICATION OF PHARMACOPERONES FOR THE GONADOTROPIN RELEASING HORMONE RECEPTOR.ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES. VOL. 12. ISSUE 4. P. 238-246 26 36% 0
10 ULLOA-AGUIRRE, A , CONN, PM , (2016) PHARMACOPERONES AS A NEW THERAPEUTIC APPROACH: IN VITRO IDENTIFICATION AND IN VIVO VALIDATION OF BIOACTIVE MOLECULES.CURRENT DRUG TARGETS. VOL. 17. ISSUE 13. P. 1471 -1481 28 30% 0

Classes with closest relation at Level 1


Rank Class id link
1 9142 RECEPTOR MOSAICS//HETEROMER//RECEPTOR RECEPTOR INTERACTIONS
2 7919 AQUAPORIN 2//NEPHROGENIC DIABETES INSIPIDUS//KIDNEY ELE OLYTE METAB
3 11174 KALLMANN SYNDROME//PROKINETICIN//HYPOGONADOTROPIC HYPOGONADISM
4 21073 EXPLORATORY DISCOVERY//LHRH ANTAGONIST//AZALINE B
5 2801 GNRH RECEPTOR//GONADOTROPES//ALPHA T3 1 CELLS
6 2285 G PROTEIN COUPLED RECEPTOR KINASE//ARRESTIN//BETA ARRESTIN
7 4196 G PROTEIN COUPLED RECEPTOR//GPCR//MEMBRANE PROT STRUCT FUNCT UNIT
8 4878 FSH RECEPTOR//FOLLICLE STIMULATING HORMONE RECEPTOR//LUTEINIZING HORMONE RECEPTOR
9 9490 ALPHA2 ADRENOCEPTOR SUBTYPES//ALPHA2C ADRENOCEPTOR//ALPHA2A ADRENOCEPTOR
10 5128 ERAD//VALOSIN CONTAINING PROTEIN//P97

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