Class information for:
Level 1: AQUAPORIN 2//NEPHROGENIC DIABETES INSIPIDUS//KIDNEY ELE OLYTE METAB

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
7919 1314 42.3 83%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
222 3       MYOTONIC DYSTROPHY//ALDOSTERONE//PHYSIOLOGY 49798
1897 2             AQUAPORIN//WATER CHANNEL//AQUAPORIN 2 5939
7919 1                   AQUAPORIN 2//NEPHROGENIC DIABETES INSIPIDUS//KIDNEY ELE OLYTE METAB 1314

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 AQUAPORIN 2 authKW 2655907 13% 65% 176
2 NEPHROGENIC DIABETES INSIPIDUS authKW 1828132 10% 62% 127
3 KIDNEY ELE OLYTE METAB address 884912 8% 36% 106
4 AQP2 authKW 715241 4% 63% 49
5 EPITHELIAL SYST BIOL address 547383 3% 67% 35
6 WATER SALT address 489783 7% 24% 87
7 AVPR2 authKW 432556 2% 85% 22
8 COLLECTING DUCT authKW 313893 7% 15% 88
9 CONGENITAL NEPHROGENIC DIABETES INSIPIDUS authKW 278842 1% 100% 12
10 WATER CHANNEL authKW 218078 6% 13% 75

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Urology & Nephrology 28855 43% 0% 567
2 Physiology 11533 32% 0% 426
3 Endocrinology & Metabolism 482 9% 0% 112
4 Cell Biology 352 10% 0% 135
5 Pediatrics 317 6% 0% 83
6 Medicine, Research & Experimental 231 6% 0% 80
7 Biochemistry & Molecular Biology 94 12% 0% 155
8 Genetics & Heredity 84 5% 0% 63
9 Transplantation 68 2% 0% 25
10 Medicine, General & Internal 39 4% 0% 57

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 KIDNEY ELE OLYTE METAB 884912 8% 36% 106
2 EPITHELIAL SYST BIOL 547383 3% 67% 35
3 WATER SALT 489783 7% 24% 87
4 HOMEOSTASIS MED NEPHROL 110641 1% 48% 10
5 INTERACT PROT EPITHELIAL TRANSPORT INTERPRET 92943 0% 67% 6
6 MGH SYST BIOL 87579 1% 54% 7
7 PROGRAM MEMBRANE BIOL 85884 2% 13% 28
8 PROGRAM MEMBRANE BIOL RENAL UNIT 46474 0% 100% 2
9 RENAL UNIT HYPERTENS 46474 0% 100% 2
10 RUNMC NIJMEGEN 46474 0% 100% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY 211453 19% 4% 244
2 JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY 17960 6% 1% 75
3 NEPHRON PHYSIOLOGY 6383 1% 4% 7
4 KIDNEY INTERNATIONAL 4103 4% 0% 51
5 AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 3478 3% 0% 33
6 PEDIATRIC NEPHROLOGY 3185 2% 0% 29
7 SEMINARS IN NEPHROLOGY 1724 1% 1% 12
8 PROCEEDINGS OF THE ASSOCIATION OF AMERICAN PHYSICIANS 1541 0% 2% 4
9 PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY 1095 2% 0% 20
10 NEPHROLOGY DIALYSIS TRANSPLANTATION 957 2% 0% 23

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 AQUAPORIN 2 2655907 13% 65% 176 Search AQUAPORIN+2 Search AQUAPORIN+2
2 NEPHROGENIC DIABETES INSIPIDUS 1828132 10% 62% 127 Search NEPHROGENIC+DIABETES+INSIPIDUS Search NEPHROGENIC+DIABETES+INSIPIDUS
3 AQP2 715241 4% 63% 49 Search AQP2 Search AQP2
4 AVPR2 432556 2% 85% 22 Search AVPR2 Search AVPR2
5 COLLECTING DUCT 313893 7% 15% 88 Search COLLECTING+DUCT Search COLLECTING+DUCT
6 CONGENITAL NEPHROGENIC DIABETES INSIPIDUS 278842 1% 100% 12 Search CONGENITAL+NEPHROGENIC+DIABETES+INSIPIDUS Search CONGENITAL+NEPHROGENIC+DIABETES+INSIPIDUS
7 WATER CHANNEL 218078 6% 13% 75 Search WATER+CHANNEL Search WATER+CHANNEL
8 AQUAPORIN 199803 10% 7% 129 Search AQUAPORIN Search AQUAPORIN
9 VASOPRESSIN 173415 14% 4% 187 Search VASOPRESSIN Search VASOPRESSIN
10 AQUAPORIN 2 WATER CHANNEL 148713 1% 80% 8 Search AQUAPORIN+2+WATER+CHANNEL Search AQUAPORIN+2+WATER+CHANNEL

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 VUKICEVIC, T , SCHULZ, M , FAUST, D , KLUSSMANN, E , (2016) THE TRAFFICKING OF THE WATER CHANNEL AQUAPORIN-2 IN RENAL PRINCIPAL CELLS-A POTENTIAL TARGET FOR PHARMACOLOGICAL INTERVENTION IN CARDIOVASCULAR DISEASES.FRONTIERS IN PHARMACOLOGY. VOL. 7. ISSUE . P. - 208 56% 3
2 KORTENOEVEN, MLA , FENTON, RA , (2014) RENAL AQUAPORINS AND WATER BALANCE DISORDERS.BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS. VOL. 1840. ISSUE 5. P. 1533 -1549 138 58% 36
3 WESCHE, D , DEEN, PMT , KNOERS, NVAM , (2012) CONGENITAL NEPHROGENIC DIABETES INSIPIDUS: THE CURRENT STATE OF AFFAIRS.PEDIATRIC NEPHROLOGY. VOL. 27. ISSUE 12. P. 2183-2204 119 73% 32
4 MOELLER, HB , RITTIG, S , FENTON, RA , (2013) NEPHROGENIC DIABETES INSIPIDUS: ESSENTIAL INSIGHTS INTO THE MOLECULAR BACKGROUND AND POTENTIAL THERAPIES FOR TREATMENT.ENDOCRINE REVIEWS. VOL. 34. ISSUE 2. P. 278-301 115 65% 40
5 JUNG, HJ , KWON, TH , (2016) MOLECULAR MECHANISMS REGULATING AQUAPORIN-2 IN KIDNEY COLLECTING DUCT.AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY. VOL. 311. ISSUE 6. P. F1318 -F1328 112 76% 0
6 WILSON, JLL , MIRANDA, CA , KNEPPER, MA , (2013) VASOPRESSIN AND THE REGULATION OF AQUAPORIN-2.CLINICAL AND EXPERIMENTAL NEPHROLOGY. VOL. 17. ISSUE 6. P. 751-764 106 73% 26
7 ROBBEN, JH , KNOERS, NVAM , DEEN, PMT , (2006) CELL BIOLOGICAL ASPECTS OF THE VASOPRESSIN TYPE-2 RECEPTOR AND AQUAPORIN 2 WATER CHANNEL IN NEPHROGENIC DIABETES INSIPIDUS.AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY. VOL. 291. ISSUE 2. P. F257 -F270 119 75% 72
8 MOELLER, HB , FENTON, RA , (2012) CELL BIOLOGY OF VASOPRESSIN-REGULATED AQUAPORIN-2 TRAFFICKING.PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY. VOL. 464. ISSUE 2. P. 133 -144 93 79% 26
9 NODA, Y , (2014) DYNAMIC REGULATION AND DYSREGULATION OF THE WATER CHANNEL AQUAPORIN-2: A COMMON CAUSE OF AND PROMISING THERAPEUTIC TARGET FOR WATER BALANCE DISORDERS.CLINICAL AND EXPERIMENTAL NEPHROLOGY. VOL. 18. ISSUE 4. P. 558 -570 97 80% 0
10 BOCKENHAUER, D , BICHET, DG , (2015) PATHOPHYSIOLOGY, DIAGNOSIS AND MANAGEMENT OF NEPHROGENIC DIABETES INSIPIDUS.NATURE REVIEWS NEPHROLOGY. VOL. 11. ISSUE 10. P. 576 -588 74 72% 14

Classes with closest relation at Level 1


Rank Class id link
1 30920 PHARMACOPERONE//ER EXPORT MOTIF//EXPORT TRAFFICKING
2 16661 TOAD URINARY BLADDER//INTRAMEMBRANE PARTICLE AGGREGATES//TIGHT EPITHELIA
3 12114 URINE CONCENTRATING MECHANISM//UREA TRANSPORT//UREA TRANSPORTER
4 1287 AQUAPORIN//WATER CHANNEL//AQUAPORIN 4
5 15479 DIABETES INSIPIDUS//CENTRAL DIABETES INSIPIDUS//ADIPSIA
6 28371 PATHOPHYSIOL EXPT NEUROENDOCRINOL//NK 1 NK 2 RECEPTORS//BIOMED PHYSIOL MED BIOPHYS
7 6585 OPC 21268//YM087//VASOPRESSIN RECEPTOR ANTAGONIST
8 22828 LITHIUM CLEARANCE//SNGFR//GLOMERULO TUBULAR BALANCE
9 7705 LITHIUM INTOXICATION//LITHIUM//LITHIUM TOXICITY
10 7294 OXYTOCIN RECEPTOR//OXYTOCIN ANTAGONIST//U469

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