Class information for:
Level 2: AQUAPORIN//WATER CHANNEL//AQUAPORIN 2

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
1897 5939 40.1 74%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
222 3       MYOTONIC DYSTROPHY//ALDOSTERONE//PHYSIOLOGY 49798
1897 2             AQUAPORIN//WATER CHANNEL//AQUAPORIN 2 5939
1287 1                   AQUAPORIN//WATER CHANNEL//AQUAPORIN 4 2742
7919 1                   AQUAPORIN 2//NEPHROGENIC DIABETES INSIPIDUS//KIDNEY ELE OLYTE METAB 1314
12114 1                   URINE CONCENTRATING MECHANISM//UREA TRANSPORT//UREA TRANSPORTER 931
16661 1                   TOAD URINARY BLADDER//INTRAMEMBRANE PARTICLE AGGREGATES//TIGHT EPITHELIA 642
24479 1                   WATER CHANNEL PROTEIN//GENET EXPLORAT 1//NEAR MEMBRANE NERNST LAYERS 310

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 AQUAPORIN authKW 2053386 15% 45% 879
2 WATER CHANNEL authKW 1068888 6% 59% 353
3 AQUAPORIN 2 authKW 648968 3% 68% 185
4 AQUAPORIN 4 authKW 446333 4% 39% 220
5 NEPHROGENIC DIABETES INSIPIDUS authKW 443389 2% 65% 133
6 AQUAPORIN 1 authKW 433853 2% 58% 145
7 KIDNEY ELE OLYTE METAB address 351156 2% 48% 142
8 AQP4 authKW 342603 2% 66% 101
9 WATER SALT address 276436 2% 39% 139
10 AQUAPORIN 5 authKW 260522 1% 65% 78

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Physiology 29001 24% 0% 1453
2 Urology & Nephrology 17749 16% 0% 976
3 Cell Biology 3704 14% 0% 858
4 Biochemistry & Molecular Biology 3033 22% 0% 1324
5 Biophysics 2010 8% 0% 456
6 Medicine, Research & Experimental 735 5% 0% 316
7 Neurosciences 563 8% 0% 493
8 CYTOLOGY & HISTOLOGY 482 0% 0% 28
9 Endocrinology & Metabolism 301 4% 0% 240
10 Biology 222 2% 0% 146

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 KIDNEY ELE OLYTE METAB 351156 2% 48% 142
2 WATER SALT 276436 2% 39% 139
3 EPITHELIAL SYST BIOL 135288 1% 71% 37
4 GEN ENVIRONM PHYSIOL 47890 1% 21% 45
5 DIPARTIMENTO FISIOL GEN AMBIENTALE 46599 1% 20% 45
6 PROGRAM MEMBRANE BIOL 42698 1% 20% 42
7 MEMBRANE CHANNEL 40312 0% 41% 19
8 HOMEOSTASIS MED NEPHROL 35233 0% 57% 12
9 GENET EXPLORAT 1 29899 0% 73% 8
10 BIOQUIM BIOL HUMANA 29730 0% 64% 9

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY 141415 7% 7% 425
2 AMERICAN JOURNAL OF PHYSIOLOGY 15621 5% 1% 277
3 BIOLOGY OF THE CELL 10314 1% 3% 71
4 JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY 8556 2% 2% 111
5 JOURNAL OF MEMBRANE BIOLOGY 8423 1% 2% 88
6 KIDNEY INTERNATIONAL 6733 2% 1% 140
7 PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY 5595 2% 1% 96
8 AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 4678 1% 1% 82
9 MOLECULAR ASPECTS OF MEDICINE 2617 0% 3% 18
10 SEMINARS IN NEPHROLOGY 2357 1% 2% 30

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 AQUAPORIN 2053386 15% 45% 879 Search AQUAPORIN Search AQUAPORIN
2 WATER CHANNEL 1068888 6% 59% 353 Search WATER+CHANNEL Search WATER+CHANNEL
3 AQUAPORIN 2 648968 3% 68% 185 Search AQUAPORIN+2 Search AQUAPORIN+2
4 AQUAPORIN 4 446333 4% 39% 220 Search AQUAPORIN+4 Search AQUAPORIN+4
5 NEPHROGENIC DIABETES INSIPIDUS 443389 2% 65% 133 Search NEPHROGENIC+DIABETES+INSIPIDUS Search NEPHROGENIC+DIABETES+INSIPIDUS
6 AQUAPORIN 1 433853 2% 58% 145 Search AQUAPORIN+1 Search AQUAPORIN+1
7 AQP4 342603 2% 66% 101 Search AQP4 Search AQP4
8 AQUAPORIN 5 260522 1% 65% 78 Search AQUAPORIN+5 Search AQUAPORIN+5
9 AQUAPORIN 3 252223 1% 71% 69 Search AQUAPORIN+3 Search AQUAPORIN+3
10 UREA TRANSPORT 224958 1% 72% 61 Search UREA+TRANSPORT Search UREA+TRANSPORT

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 VUKICEVIC, T , SCHULZ, M , FAUST, D , KLUSSMANN, E , (2016) THE TRAFFICKING OF THE WATER CHANNEL AQUAPORIN-2 IN RENAL PRINCIPAL CELLS-A POTENTIAL TARGET FOR PHARMACOLOGICAL INTERVENTION IN CARDIOVASCULAR DISEASES.FRONTIERS IN PHARMACOLOGY. VOL. 7. ISSUE . P. - 276 75% 3
2 NIELSEN, S , FROKIAER, J , MARPLES, D , KWON, TH , AGRE, P , KNEPPER, MA , (2002) AQUAPORINS IN THE KIDNEY: FROM MOLECULES TO MEDICINE.PHYSIOLOGICAL REVIEWS. VOL. 82. ISSUE 1. P. 205 -244 210 89% 623
3 TAKATA, K , MATSUZAKI, T , TAJIKA, Y , (2004) AQUAPORINS: WATER CHANNEL PROTEINS OF THE CELL MEMBRANE.PROGRESS IN HISTOCHEMISTRY AND CYTOCHEMISTRY. VOL. 39. ISSUE 1. P. 1-83 262 84% 181
4 KORTENOEVEN, MLA , FENTON, RA , (2014) RENAL AQUAPORINS AND WATER BALANCE DISORDERS.BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS. VOL. 1840. ISSUE 5. P. 1533 -1549 185 78% 36
5 VERKMAN, AS , ANDERSON, MO , PAPADOPOULOS, MC , (2014) AQUAPORINS: IMPORTANT BUT ELUSIVE DRUG TARGETS.NATURE REVIEWS DRUG DISCOVERY. VOL. 13. ISSUE 4. P. 259 -277 143 79% 89
6 ZELENINA, M , (2010) REGULATION OF BRAIN AQUAPORINS.NEUROCHEMISTRY INTERNATIONAL. VOL. 57. ISSUE 4. P. 468-488 216 79% 53
7 KLEIN, JD , BLOUNT, MA , SANDS, JM , (2011) UREA TRANSPORT IN THE KIDNEY.COMPREHENSIVE PHYSIOLOGY. VOL. 1. ISSUE 2. P. 699-729 250 73% 11
8 NAGELHUS, EA , OTTERSEN, OP , (2013) PHYSIOLOGICAL ROLES OF AQUAPORIN-4 IN BRAIN.PHYSIOLOGICAL REVIEWS. VOL. 93. ISSUE 4. P. 1543 -1562 155 75% 70
9 ZHU, C , JIANG, ZY , BAZER, FW , JOHNSON, GA , BURGHARDT, RC , WU, GY , (2015) AQUAPORINS IN THE FEMALE REPRODUCTIVE SYSTEM OF MAMMALS.FRONTIERS IN BIOSCIENCE-LANDMARK. VOL. 20. ISSUE . P. 838 -871 169 79% 7
10 ROJEK, A , PRAETORIUS, J , FROKIAER, J , NIELSEN, S , FENTON, RA , (2008) A CURRENT VIEW OF THE MAMMALIAN AQUAGLYCEROPORINS.ANNUAL REVIEW OF PHYSIOLOGY. VOL. 70. ISSUE . P. 301-327 147 93% 135

Classes with closest relation at Level 2


Rank Class id link
1 1141 INTRACELLULAR PH//NA H EXCHANGER//AMERICAN JOURNAL OF PHYSIOLOGY
2 2157 GRAVITROPISM//AQUAPORIN//ENDODERMIS
3 1248 ALDOSTERONE//GITELMAN SYNDROME//BARTTER SYNDROME
4 276 OXYTOCIN//VASOPRESSIN//HYPONATREMIA
5 1894 CYSTINURIA//REGULATORY VOLUME DECREASE//CELL VOLUME REGULATION
6 2253 RENAL DENERVATION//RESISTANT HYPERTENSION//RENAL SYMPATHETIC DENERVATION
7 1054 GLUTAMATE TRANSPORTER//ASTROCYTES//GLIA
8 2404 HUMMINGBIRDS//SGLT1//NA ATPASE
9 1808 LITHIUM//GLYCOGEN SYNTHASE KINASE 3//GSK 3
10 1245 ERYPTOSIS//BAND 3//HEREDITARY SPHEROCYTOSIS

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