Class information for:
Level 2: ALDOSTERONE//GITELMAN SYNDROME//BARTTER SYNDROME

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
1248 8969 39.5 76%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
222 3       MYOTONIC DYSTROPHY//ALDOSTERONE//PHYSIOLOGY 49798
1248 2             ALDOSTERONE//GITELMAN SYNDROME//BARTTER SYNDROME 8969
1897 1                   ALDOSTERONE//EPLERENONE//SPIRONOLACTONE 2437
2208 1                   ENAC//EPITHELIAL SODIUM CHANNEL//LIDDLES SYNDROME 2322
6141 1                   WNK//WNK4//WNK KINASE 1523
10424 1                   HYPERKALEMIA//KAYEXALATE//HYPERKALAEMIA 1065
12723 1                   GITELMAN SYNDROME//BARTTER SYNDROME//HYPOCALCIURIA 885
20223 1                   SGK1//SERUM AND GLUCOCORTICOID INDUCIBLE KINASE//SGK 470
25953 1                   PSEUDOHYPOALDOSTERONISM//TRANSIENT PSEUDOHYPOALDOSTERONISM//SALT LOSS 267

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 ALDOSTERONE authKW 1395785 14% 34% 1223
2 GITELMAN SYNDROME authKW 590751 2% 89% 195
3 BARTTER SYNDROME authKW 516904 2% 73% 207
4 HYPERKALEMIA authKW 475239 3% 45% 311
5 EPLERENONE authKW 438668 2% 68% 189
6 MINERALOCORTICOID RECEPTOR authKW 384584 4% 35% 327
7 SPIRONOLACTONE authKW 359335 3% 35% 298
8 ENAC authKW 324030 2% 46% 205
9 EPITHELIAL SODIUM CHANNEL authKW 296222 2% 45% 194
10 PSEUDOHYPOALDOSTERONISM authKW 258759 1% 89% 85

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Physiology 48329 26% 1% 2300
2 Urology & Nephrology 38182 19% 1% 1745
3 Peripheral Vascular Diseases 8684 10% 0% 875
4 Endocrinology & Metabolism 4449 10% 0% 869
5 Cell Biology 2411 10% 0% 923
6 Cardiac & Cardiovascular System 2005 7% 0% 639
7 Biochemistry & Molecular Biology 1754 16% 0% 1426
8 Pediatrics 1188 5% 0% 446
9 Medicine, General & Internal 972 7% 0% 584
10 Medicine, Research & Experimental 309 3% 0% 307

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MOL PHYSIOL UNIT 102244 1% 48% 63
2 U478 66906 1% 40% 49
3 RENAL ELE OLYTE 63162 1% 18% 102
4 ZELLULARE MOL PHYSIOL 51653 0% 56% 27
5 CELL MOL SIGNALING 30581 0% 30% 30
6 NEPHROL 21835 7% 1% 651
7 CLIN EPIGENET 20825 0% 44% 14
8 P MOL MED 20007 0% 59% 10
9 J AN FOOD EDUC HLTH 19815 0% 45% 13
10 NACL CIENCIAS MED NUTR SALVADOR ZUBIRAN 19452 0% 22% 26

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY 88134 5% 6% 413
2 PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY 28230 3% 3% 263
3 JOURNAL OF MEMBRANE BIOLOGY 28139 2% 4% 197
4 AMERICAN JOURNAL OF PHYSIOLOGY 20882 4% 2% 394
5 HYPERTENSION 15074 3% 2% 228
6 CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION 11615 1% 5% 74
7 JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY 11024 2% 2% 155
8 KIDNEY INTERNATIONAL 10824 2% 2% 218
9 AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 10009 2% 2% 147
10 CELLULAR PHYSIOLOGY AND BIOCHEMISTRY 9797 1% 3% 99

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class		 LCSH search Wikipedia search
1 ALDOSTERONE 1395785 14% 34% 1223 Search ALDOSTERONE Search ALDOSTERONE
2 GITELMAN SYNDROME 590751 2% 89% 195 Search GITELMAN+SYNDROME Search GITELMAN+SYNDROME
3 BARTTER SYNDROME 516904 2% 73% 207 Search BARTTER+SYNDROME Search BARTTER+SYNDROME
4 HYPERKALEMIA 475239 3% 45% 311 Search HYPERKALEMIA Search HYPERKALEMIA
5 EPLERENONE 438668 2% 68% 189 Search EPLERENONE Search EPLERENONE
6 MINERALOCORTICOID RECEPTOR 384584 4% 35% 327 Search MINERALOCORTICOID+RECEPTOR Search MINERALOCORTICOID+RECEPTOR
7 SPIRONOLACTONE 359335 3% 35% 298 Search SPIRONOLACTONE Search SPIRONOLACTONE
8 ENAC 324030 2% 46% 205 Search ENAC Search ENAC
9 EPITHELIAL SODIUM CHANNEL 296222 2% 45% 194 Search EPITHELIAL+SODIUM+CHANNEL Search EPITHELIAL+SODIUM+CHANNEL
10 PSEUDOHYPOALDOSTERONISM 258759 1% 89% 85 Search PSEUDOHYPOALDOSTERONISM Search PSEUDOHYPOALDOSTERONISM

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 JAISSER, F , FARMAN, N , (2016) EMERGING ROLES OF THE MINERALOCORTICOID RECEPTOR IN PATHOLOGY: TOWARD NEW PARADIGMS IN CLINICAL PHARMACOLOGY.PHARMACOLOGICAL REVIEWS. VOL. 68. ISSUE 1. P. 49 -75 220 69% 14
2 GARTY, H , PALMER, LG , (1997) EPITHELIAL SODIUM CHANNELS: FUNCTION, STRUCTURE, AND REGULATION.PHYSIOLOGICAL REVIEWS. VOL. 77. ISSUE 2. P. 359 -396 248 68% 840
3 HADCHOUEL, J , ELLISON, DH , GAMBA, G , (2016) REGULATION OF RENAL ELECTROLYTE TRANSPORT BY WNK AND SPAK-OSR1 KINASES.ANNUAL REVIEW OF PHYSIOLOGY, VOL 78. VOL. 78. ISSUE . P. 367 -389 116 94% 9
4 KOSTAKIS, ID , CHOLIDOU, KG , PERREA, D , (2012) SYNDROMES OF IMPAIRED ION HANDLING IN THE DISTAL NEPHRON: PSEUDOHYPOALDOSTERONISM AND FAMILIAL HYPERKALEMIC HYPERTENSION.HORMONES-INTERNATIONAL JOURNAL OF ENDOCRINOLOGY AND METABOLISM. VOL. 11. ISSUE 1. P. 31 -53 206 89% 1
5 LOFFING, J , KORBMACHER, C , (2009) REGULATED SODIUM TRANSPORT IN THE RENAL CONNECTING TUBULE (CNT) VIA THE EPITHELIAL SODIUM CHANNEL (ENAC).PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY. VOL. 458. ISSUE 1. P. 111 -135 220 66% 67
6 MCCORMICK, JA , ELLISON, DH , (2015) DISTAL CONVOLUTED TUBULE.COMPREHENSIVE PHYSIOLOGY. VOL. 5. ISSUE 1. P. 45 -98 240 48% 8
7 HERMIDORFF, M , DE ASSIS, LVM , ISOLDI, MC , (2017) GENOMIC AND RAPID EFFECTS OF ALDOSTERONE: WHAT WE KNOW AND DO NOT KNOW THUS FAR.HEART FAILURE REVIEWS. VOL. 22. ISSUE 1. P. 65 -89 178 70% 0
8 PENTON, D , CZOGALLA, J , LOFFING, J , (2015) DIETARY POTASSIUM AND THE RENAL CONTROL OF SALT BALANCE AND BLOOD PRESSURE.PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY. VOL. 467. ISSUE 3. P. 513 -530 138 75% 11
9 HANUKOGLU, I , HANUKOGLU, A , (2016) EPITHELIAL SODIUM CHANNEL (ENAC) FAMILY: PHYLOGENY, STRUCTURE-FUNCTION, TISSUE DISTRIBUTION, AND ASSOCIATED INHERITED DISEASES.GENE. VOL. 579. ISSUE 2. P. 95 -132 162 54% 4
10 LANG, F , BOHMER, C , PALMADA, M , SEEBOHM, G , STRUTZ-SEEBOHM, N , VALLON, V , (2006) (PATHO)PHYSIOLOGICAL SIGNIFICANCE OF THE SERUM- AND GLUCOCORTICOID-INDUCIBLE KINASE ISOFORMS.PHYSIOLOGICAL REVIEWS. VOL. 86. ISSUE 4. P. 1151-1178 190 52% 247

Classes with closest relation at Level 2


Rank Class id link
1 1141 INTRACELLULAR PH//NA H EXCHANGER//AMERICAN JOURNAL OF PHYSIOLOGY
2 2727 11 BETA HYDROXYSTEROID DEHYDROGENASE//11 BETA HYDROXYSTEROID DEHYDROGENASE TYPE 1//11 BETA HSD1
3 1897 AQUAPORIN//WATER CHANNEL//AQUAPORIN 2
4 3713 A20//LAPTM4B//WWP1
5 2253 RENAL DENERVATION//RESISTANT HYPERTENSION//RENAL SYMPATHETIC DENERVATION
6 2003 MYOTONIC DYSTROPHY//MYOTONIA//MYOTONIC DYSTROPHY TYPE 1
7 942 HEART FAILURE//ACUTE HEART FAILURE//EUROPEAN JOURNAL OF HEART FAILURE
8 1330 SODIUM LITHIUM COUNTERTRANSPORT//SODIUM//SALT SENSITIVITY
9 2418 HYDROCHLOROTHIAZIDE//CICLETANINE//TORASEMIDE
10 1894 CYSTINURIA//REGULATORY VOLUME DECREASE//CELL VOLUME REGULATION

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