Class information for:
Level 1: ALDOSTERONE//EPLERENONE//SPIRONOLACTONE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
1897 2437 44.3 87%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
222 3       MYOTONIC DYSTROPHY//ALDOSTERONE//PHYSIOLOGY 49798
1248 2             ALDOSTERONE//GITELMAN SYNDROME//BARTTER SYNDROME 8969
1897 1                   ALDOSTERONE//EPLERENONE//SPIRONOLACTONE 2437

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ALDOSTERONE authKW 2878594 38% 25% 915
2 EPLERENONE authKW 1564577 8% 67% 186
3 SPIRONOLACTONE authKW 1219560 12% 34% 286
4 MINERALOCORTICOID RECEPTOR authKW 1192742 12% 32% 300
5 MINERALOCORTICOID RECEPTOR ANTAGONISTS authKW 513388 3% 58% 71
6 MINERALOCORTICOID authKW 264984 4% 21% 101
7 ALDOSTERONE ANTAGONISTS authKW 168392 2% 34% 40
8 ALDOSTERONE BREAKTHROUGH authKW 151230 1% 93% 13
9 ALDOSTERONE RECEPTOR ANTAGONIST authKW 144437 1% 82% 14
10 ALDOSTERONE BLOCKER authKW 124538 1% 76% 13

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Peripheral Vascular Diseases 15668 24% 0% 581
2 Cardiac & Cardiovascular System 6681 21% 0% 520
3 Endocrinology & Metabolism 5543 19% 0% 467
4 Urology & Nephrology 2827 11% 0% 257
5 Physiology 1649 10% 0% 239
6 Pharmacology & Pharmacy 779 13% 0% 312
7 Cell Biology 226 7% 0% 171
8 Medicine, Research & Experimental 103 4% 0% 89
9 Medicine, General & Internal 62 4% 0% 101
10 Biochemistry & Molecular Biology 40 9% 0% 208

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 U478 59110 1% 20% 24
2 JULIUS BERNSTEIN PHYSIOL 43813 1% 17% 21
3 STICA 37584 0% 100% 3
4 GLOBAL DEV STAT 34796 0% 56% 5
5 ENDOCRINOL DIABET HYPERTENS MED 31699 0% 28% 9
6 WELLCOME TRUST CELLULAR PHYSIOL UNIT 29223 0% 33% 7
7 FEDERATIF RECH CELLULES EPITHELIALES 28467 0% 45% 5
8 INVEST CLIN 9501 26084 0% 21% 10
9 CARDIO METAB DIS 25056 0% 100% 2
10 CLIN SCI CLIN PHARMACOL CARDIOVASC HEMATOL 25056 0% 100% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 HYPERTENSION 29959 7% 1% 166
2 JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM 23908 2% 5% 41
3 CURRENT HYPERTENSION REPORTS 17272 2% 4% 38
4 HYPERTENSION RESEARCH 9725 2% 2% 44
5 MOLECULAR AND CELLULAR ENDOCRINOLOGY 4144 2% 1% 54
6 STEROIDS 4110 2% 1% 38
7 AMERICAN JOURNAL OF HYPERTENSION 3679 2% 1% 42
8 HEART FAILURE REVIEWS 3605 1% 2% 14
9 ENDOCRINOLOGY 3365 3% 0% 83
10 CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION 3122 1% 1% 20

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 ALDOSTERONE 2878594 38% 25% 915 Search ALDOSTERONE Search ALDOSTERONE
2 EPLERENONE 1564577 8% 67% 186 Search EPLERENONE Search EPLERENONE
3 SPIRONOLACTONE 1219560 12% 34% 286 Search SPIRONOLACTONE Search SPIRONOLACTONE
4 MINERALOCORTICOID RECEPTOR 1192742 12% 32% 300 Search MINERALOCORTICOID+RECEPTOR Search MINERALOCORTICOID+RECEPTOR
5 MINERALOCORTICOID RECEPTOR ANTAGONISTS 513388 3% 58% 71 Search MINERALOCORTICOID+RECEPTOR+ANTAGONISTS Search MINERALOCORTICOID+RECEPTOR+ANTAGONISTS
6 MINERALOCORTICOID 264984 4% 21% 101 Search MINERALOCORTICOID Search MINERALOCORTICOID
7 ALDOSTERONE ANTAGONISTS 168392 2% 34% 40 Search ALDOSTERONE+ANTAGONISTS Search ALDOSTERONE+ANTAGONISTS
8 ALDOSTERONE BREAKTHROUGH 151230 1% 93% 13 Search ALDOSTERONE+BREAKTHROUGH Search ALDOSTERONE+BREAKTHROUGH
9 ALDOSTERONE RECEPTOR ANTAGONIST 144437 1% 82% 14 Search ALDOSTERONE+RECEPTOR+ANTAGONIST Search ALDOSTERONE+RECEPTOR+ANTAGONIST
10 ALDOSTERONE BLOCKER 124538 1% 76% 13 Search ALDOSTERONE+BLOCKER Search ALDOSTERONE+BLOCKER

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 JAISSER, F , FARMAN, N , (2016) EMERGING ROLES OF THE MINERALOCORTICOID RECEPTOR IN PATHOLOGY: TOWARD NEW PARADIGMS IN CLINICAL PHARMACOLOGY.PHARMACOLOGICAL REVIEWS. VOL. 68. ISSUE 1. P. 49 -75 201 63% 14
2 HIRSCH, JS , DREXLER, Y , BOMBACK, AS , (2014) ALDOSTERONE BLOCKADE IN CHRONIC KIDNEY DISEASE.SEMINARS IN NEPHROLOGY. VOL. 34. ISSUE 3. P. 307 -322 123 82% 10
3 BRIET, M , SCHIFFRIN, EL , (2010) ALDOSTERONE: EFFECTS ON THE KIDNEY AND CARDIOVASCULAR SYSTEM.NATURE REVIEWS NEPHROLOGY. VOL. 6. ISSUE 5. P. 261 -273 107 78% 117
4 TAMARGO, J , SOLINI, A , RUILOPE, LM , (2014) COMPARISON OF AGENTS THAT AFFECT ALDOSTERONE ACTION.SEMINARS IN NEPHROLOGY. VOL. 34. ISSUE 3. P. 285 -306 120 74% 9
5 HERMIDORFF, M , DE ASSIS, LVM , ISOLDI, MC , (2017) GENOMIC AND RAPID EFFECTS OF ALDOSTERONE: WHAT WE KNOW AND DO NOT KNOW THUS FAR.HEART FAILURE REVIEWS. VOL. 22. ISSUE 1. P. 65 -89 149 59% 0
6 BAUERSACHS, J , JAISSER, F , TOTO, R , (2015) MINERALOCORTICOID RECEPTOR ACTIVATION AND MINERALOCORTICOID RECEPTOR ANTAGONIST TREATMENT IN CARDIAC AND RENAL DISEASES.HYPERTENSION. VOL. 65. ISSUE 2. P. 257 -U42 85 83% 17
7 MEINEL, S , GEKLE, M , GROSSMANN, C , (2014) MINERALOCORTICOID RECEPTOR SIGNALING: CROSSTALK WITH MEMBRANE RECEPTORS AND OTHER MODULATORS.STEROIDS. VOL. 91. ISSUE . P. 3 -10 98 80% 12
8 BROWN, NJ , (2013) CONTRIBUTION OF ALDOSTERONE TO CARDIOVASCULAR AND RENAL INFLAMMATION AND FIBROSIS.NATURE REVIEWS NEPHROLOGY. VOL. 9. ISSUE 8. P. 459-469 92 73% 57
9 GROSSMANN, C , GEKLE, M , (2009) NEW ASPECTS OF RAPID ALDOSTERONE SIGNALING.MOLECULAR AND CELLULAR ENDOCRINOLOGY. VOL. 308. ISSUE 1-2. P. 53-62 103 75% 65
10 MCCURLEY, A , JAFFE, IZ , (2012) MINERALOCORTICOID RECEPTORS IN VASCULAR FUNCTION AND DISEASE.MOLECULAR AND CELLULAR ENDOCRINOLOGY. VOL. 350. ISSUE 2. P. 256 -265 87 77% 51

Classes with closest relation at Level 1


Rank Class id link
1 25953 PSEUDOHYPOALDOSTERONISM//TRANSIENT PSEUDOHYPOALDOSTERONISM//SALT LOSS
2 3453 PRIMARY ALDOSTERONISM//HYPERALDOSTERONISM//ALDOSTERONE PRODUCING ADENOMA
3 10424 HYPERKALEMIA//KAYEXALATE//HYPERKALAEMIA
4 20223 SGK1//SERUM AND GLUCOCORTICOID INDUCIBLE KINASE//SGK
5 6616 CARDIAC FIBROBLASTS//ANGIOTENSIN II//CARDIAC HYPERTROPHY
6 1795 11 BETA HYDROXYSTEROID DEHYDROGENASE//11 BETA HYDROXYSTEROID DEHYDROGENASE TYPE 1//11 BETA HSD1
7 17641 HIGH BLOOD P SURE UNIT//ST GEORGE HOSP RENAL MED//ASSOCIATED MEASURES
8 2021 BETA BLOCKERS//HEART FAILURE//CARVEDILOL
9 4584 PROTEINURIA//ANGIOTENSIN RECEPTOR BLOCKER//DUAL BLOCKADE
10 9376 ALISKIREN//PRORENIN RECEPTOR//DIRECT RENIN INHIBITOR

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