Class information for:
Level 2: 11 BETA HYDROXYSTEROID DEHYDROGENASE//11 BETA HYDROXYSTEROID DEHYDROGENASE TYPE 1//11 BETA HSD1

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
2727 3287 37.9 76%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
284 3       POLYCYSTIC OVARY SYNDROME//ENDOCRINOLOGY & METABOLISM//CORTISOL 42633
2727 2             11 BETA HYDROXYSTEROID DEHYDROGENASE//11 BETA HYDROXYSTEROID DEHYDROGENASE TYPE 1//11 BETA HSD1 3287
1795 1                   11 BETA HYDROXYSTEROID DEHYDROGENASE//11 BETA HYDROXYSTEROID DEHYDROGENASE TYPE 1//11 BETA HSD1 2482
17641 1                   HIGH BLOOD P SURE UNIT//ST GEORGE HOSP RENAL MED//ASSOCIATED MEASURES 589
27988 1                   RELATIVE DRUG POTENCIES//ATLANTIC LATERAL SKULL BASE CLIN//ATP CONSUMING PROCESSES 216

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 11 BETA HYDROXYSTEROID DEHYDROGENASE authKW 2360798 11% 71% 359
2 11 BETA HYDROXYSTEROID DEHYDROGENASE TYPE 1 authKW 894001 3% 87% 111
3 11 BETA HSD1 authKW 787636 3% 79% 107
4 CORTISONE authKW 292266 3% 36% 88
5 11 BETA HSD2 authKW 270839 1% 61% 48
6 MOL HYPERTENS address 270518 1% 79% 37
7 11 BETA HSD1 INHIBITOR authKW 244092 1% 91% 29
8 GLUCOCORTICOID METABOLISM authKW 211098 1% 78% 29
9 HIGH BLOOD P SURE UNIT address 179808 1% 88% 22
10 11 BETA HSD authKW 144093 1% 52% 30

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Endocrinology & Metabolism 34738 40% 0% 1305
2 Peripheral Vascular Diseases 2003 8% 0% 260
3 Physiology 1299 8% 0% 255
4 Rheumatology 623 3% 0% 92
5 Pharmacology & Pharmacy 594 10% 0% 341
6 Biochemistry & Molecular Biology 561 15% 0% 500
7 Chemistry, Medicinal 501 4% 0% 145
8 Reproductive Biology 429 3% 0% 85
9 Medicine, General & Internal 297 6% 0% 201
10 Urology & Nephrology 205 3% 0% 101

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MOL HYPERTENS 270518 1% 79% 37
2 HIGH BLOOD P SURE UNIT 179808 1% 88% 22
3 MOL SYST TOXICOL 106219 1% 37% 31
4 ENDOCRINOL UNIT 73955 4% 6% 124
5 MED CHEM CLIN PHARM 66863 0% 60% 12
6 REG ENDOCRINE UNIT 49036 0% 41% 13
7 DEV ENDOCRINE SIGNALLING 31276 0% 42% 8
8 MOLEC HYPERTENS 27864 0% 100% 3
9 ST GEORGE HOSP RENAL MED 27864 0% 100% 3
10 UFR MED SECTEUR NORD 27864 0% 100% 3

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 STEROIDS 23035 3% 2% 104
2 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 17536 4% 1% 131
3 JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 10865 5% 1% 168
4 CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY 8359 2% 1% 71
5 ENDOCRINOLOGY 6755 4% 1% 136
6 ENDOCRINE RESEARCH 6507 1% 2% 31
7 MOLECULAR AND CELLULAR ENDOCRINOLOGY 5460 2% 1% 72
8 CLINICAL ENDOCRINOLOGY 5140 2% 1% 65
9 JOURNAL OF ENDOCRINOLOGY 4916 2% 1% 67
10 CLINICAL AND EXPERIMENTAL HYPERTENSION PART A-THEORY AND PRACTICE 4539 1% 2% 26

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 11 BETA HYDROXYSTEROID DEHYDROGENASE 2360798 11% 71% 359 Search 11+BETA+HYDROXYSTEROID+DEHYDROGENASE Search 11+BETA+HYDROXYSTEROID+DEHYDROGENASE
2 11 BETA HYDROXYSTEROID DEHYDROGENASE TYPE 1 894001 3% 87% 111 Search 11+BETA+HYDROXYSTEROID+DEHYDROGENASE+TYPE+1 Search 11+BETA+HYDROXYSTEROID+DEHYDROGENASE+TYPE+1
3 11 BETA HSD1 787636 3% 79% 107 Search 11+BETA+HSD1 Search 11+BETA+HSD1
4 CORTISONE 292266 3% 36% 88 Search CORTISONE Search CORTISONE
5 11 BETA HSD2 270839 1% 61% 48 Search 11+BETA+HSD2 Search 11+BETA+HSD2
6 11 BETA HSD1 INHIBITOR 244092 1% 91% 29 Search 11+BETA+HSD1+INHIBITOR Search 11+BETA+HSD1+INHIBITOR
7 GLUCOCORTICOID METABOLISM 211098 1% 78% 29 Search GLUCOCORTICOID+METABOLISM Search GLUCOCORTICOID+METABOLISM
8 11 BETA HSD 144093 1% 52% 30 Search 11+BETA+HSD Search 11+BETA+HSD
9 HEXOSE 6 PHOSPHATE DEHYDROGENASE 139697 1% 79% 19 Search HEXOSE+6+PHOSPHATE+DEHYDROGENASE Search HEXOSE+6+PHOSPHATE+DEHYDROGENASE
10 11 BETA HYDROXYSTEROID DEHYDROGENASE 1 134108 1% 76% 19 Search 11+BETA+HYDROXYSTEROID+DEHYDROGENASE+1 Search 11+BETA+HYDROXYSTEROID+DEHYDROGENASE+1

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 CHAPMAN, K , HOLMES, M , SECKL, J , (2013) 11 BETA-HYDROXYSTEROID DEHYDROGENASES: INTRACELLULAR GATE-KEEPERS OF TISSUE GLUCOCORTICOID ACTION.PHYSIOLOGICAL REVIEWS. VOL. 93. ISSUE 3. P. 1139 -1206 477 65% 130
2 TOMLINSON, JW , WALKER, EA , BUJALSKA, IJ , DRAPER, N , LAVERY, GG , COOPER, MS , HEWISON, M , STEWART, PM , (2004) 11 BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1: A TISSUE-SPECIFIC REGULATOR OF GLUCOCORTICOID RESPONSE.ENDOCRINE REVIEWS. VOL. 25. ISSUE 5. P. 831-866 270 75% 566
3 STEWART, PM , KROZOWSKI, ZS , (1999) 11 BETA-HYDROXYSTEROID DEHYDROGENASE.VITAMINS AND HORMONES - ADVANCES IN RESEARCH AND APPLICATIONS, VOL 57. VOL. 57. ISSUE . P. 249 -324 249 74% 336
4 GATHERCOLE, LL , LAVERY, GG , MORGAN, SA , COOPER, MS , SINCLAIR, AJ , TOMLINSON, JW , STEWART, PM , (2013) 11 BETA-HYDROXYSTEROID DEHYDROGENASE 1: TRANSLATIONAL AND THERAPEUTIC ASPECTS.ENDOCRINE REVIEWS. VOL. 34. ISSUE 4. P. 525 -555 202 68% 34
5 SCOTT, JS , GOLDBERG, FW , TURNBULL, AV , (2014) MEDICINAL CHEMISTRY OF INHIBITORS OF 11 BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 (11 BETA-HSD1).JOURNAL OF MEDICINAL CHEMISTRY. VOL. 57. ISSUE 11. P. 4466 -4486 135 97% 22
6 WOODS, C , TOMLINSON, JW , (2015) THE DEHYDROGENASE HYPOTHESIS.GLUCOCORTICOID SIGNALING: FROM MOLECULES TO MICE TO MAN. VOL. 872. ISSUE . P. 353 -380 148 85% 0
7 DRAPER, N , STEWART, PM , (2005) 11 BETA-HYDROXYSTEROID DEHYDROGENASE AND THE PRE-RECEPTOR REGULATION OF CORTICOSTEROID HORMONE ACTION.JOURNAL OF ENDOCRINOLOGY. VOL. 186. ISSUE 2. P. 251-271 133 88% 228
8 PEREIRA, CD , AZEVEDO, I , MONTEIRO, R , MARTINS, MJ , (2012) 11 BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1: RELEVANCE OF ITS MODULATION IN THE PATHOPHYSIOLOGY OF OBESITY, THE METABOLIC SYNDROME AND TYPE 2 DIABETES MELLITUS.DIABETES OBESITY & METABOLISM. VOL. 14. ISSUE 10. P. 869 -881 128 79% 32
9 WHITE, PC , MUNE, T , AGARWAL, AK , (1997) 11 BETA-HYDROXYSTEROID DEHYDROGENASE AND THE SYNDROME OF APPARENT MINERALOCORTICOID EXCESS.ENDOCRINE REVIEWS. VOL. 18. ISSUE 1. P. 135 -156 145 79% 395
10 WAMIL, M , SECKL, JR , (2007) INHIBITION OF 11B-HYDROXYSTEROID DEHYDROGENASE TYPE 1 AS A PROMISING THERAPEUTIC TARGET.DRUG DISCOVERY TODAY. VOL. 12. ISSUE 13-14. P. 504-520 122 78% 98

Classes with closest relation at Level 2


Rank Class id link
1 3315 GLYCYRRHIZIN//LICORICE//GLYCYRRHIZIC ACID
2 1248 ALDOSTERONE//GITELMAN SYNDROME//BARTTER SYNDROME
3 1328 GLUCOCORTICOID RECEPTOR//ANTIPROGESTIN//JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
4 1973 ANABOLIC STEROIDS//DOPING CONTROL//DOPING ANALYSIS
5 3208 DEHYDROEPIANDROSTERONE//DHEA//DEHYDROEPIANDROSTERONE SULFATE
6 909 CONGENITAL ADRENAL HYPERPLASIA//21 HYDROXYLASE DEFICIENCY//ENDOCRINE RESEARCH
7 2373 ADRENAL INSUFFICIENCY//AIRE//APECED
8 3536 EVOLUTIONARY IMMUNOBIOL//PERITONEAL INFLAMMATION//ZYMOSAN
9 1495 KIDNEY DEVELOPMENT//FETAL PROGRAMMING//URETERIC BUD
10 1819 CORTISOL//DIGIT RATIO//PSYCHONEUROENDOCRINOLOGY

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