Class information for:
Level 1: GENISTEIN INHIBITION//TYROSINE KINASE//ANGIOTENSIN II

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
16892 629 44.0 92%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
405 3       BACTERIORHODOPSIN//G PROTEIN COUPLED RECEPTOR//G PROTEIN 29641
2998 2             RGS PROTEINS//GIRDIN//RGS 2563
16892 1                   GENISTEIN INHIBITION//TYROSINE KINASE//ANGIOTENSIN II 629

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 GENISTEIN INHIBITION authKW 145634 0% 100% 3
2 TYROSINE KINASE authKW 85675 11% 3% 70
3 ANGIOTENSIN II authKW 81913 18% 1% 115
4 ERRB address 79279 1% 23% 7
5 SIGNALISAT REGULAT CELLULAI address 54609 0% 38% 3
6 1 2 BIS2 AMINOPHENOXY authKW 48545 0% 100% 1
7 3 4 DIMETHOXYTHIOFLAVONE authKW 48545 0% 100% 1
8 A KINASE ASSOCIATED PROTEIN authKW 48545 0% 100% 1
9 AC1478 authKW 48545 0% 100% 1
10 ANGII TYPE I RECEPTOR authKW 48545 0% 100% 1

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Peripheral Vascular Diseases 2243 18% 0% 113
2 Physiology 1339 17% 0% 104
3 Biochemistry & Molecular Biology 750 31% 0% 196
4 Cell Biology 680 18% 0% 115
5 Pharmacology & Pharmacy 677 21% 0% 132
6 Cardiac & Cardiovascular System 586 13% 0% 82
7 Biophysics 301 9% 0% 56
8 Hematology 116 5% 0% 31
9 Endocrinology & Metabolism 67 5% 0% 33
10 Urology & Nephrology 62 4% 0% 23

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ERRB 79279 1% 23% 7
2 SIGNALISAT REGULAT CELLULAI 54609 0% 38% 3
3 BIMCORE MOL MODELING 48545 0% 100% 1
4 CARDIOLWMB 319 48545 0% 100% 1
5 CARDUIVASC DIC INTERNAL MED 48545 0% 100% 1
6 CELL SIGNALING HOSP UNIV MONTREAL 48545 0% 100% 1
7 CIRUGIA GEN DIGEST SECC B 48545 0% 100% 1
8 DALTON CARDIOVASC VASC BIOL MED 48545 0% 100% 1
9 DR LUDWIK ZAMENHOF MEMORIAL CHILDREN CLIN HOSP 48545 0% 100% 1
10 FAMILY MED COMMUN NURSING 48545 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 HYPERTENSION 2612 4% 0% 25
2 CIRCULATION RESEARCH 2516 4% 0% 23
3 AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 2166 3% 0% 18
4 CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY 1792 3% 0% 16
5 AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY 1536 3% 0% 20
6 JOURNAL OF BIOLOGICAL CHEMISTRY 1323 10% 0% 66
7 CELLULAR SIGNALLING 1099 2% 0% 10
8 REGULATORY PEPTIDES 818 1% 0% 9
9 MOLECULAR PHARMACOLOGY 697 2% 0% 12
10 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 693 5% 0% 32

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 GENISTEIN INHIBITION 145634 0% 100% 3 Search GENISTEIN+INHIBITION Search GENISTEIN+INHIBITION
2 TYROSINE KINASE 85675 11% 3% 70 Search TYROSINE+KINASE Search TYROSINE+KINASE
3 ANGIOTENSIN II 81913 18% 1% 115 Search ANGIOTENSIN+II Search ANGIOTENSIN+II
4 1 2 BIS2 AMINOPHENOXY 48545 0% 100% 1 Search 1+2+BIS2+AMINOPHENOXY Search 1+2+BIS2+AMINOPHENOXY
5 3 4 DIMETHOXYTHIOFLAVONE 48545 0% 100% 1 Search 3+4+DIMETHOXYTHIOFLAVONE Search 3+4+DIMETHOXYTHIOFLAVONE
6 A KINASE ASSOCIATED PROTEIN 48545 0% 100% 1 Search A+KINASE+ASSOCIATED+PROTEIN Search A+KINASE+ASSOCIATED+PROTEIN
7 AC1478 48545 0% 100% 1 Search AC1478 Search AC1478
8 ANGII TYPE I RECEPTOR 48545 0% 100% 1 Search ANGII+TYPE+I+RECEPTOR Search ANGII+TYPE+I+RECEPTOR
9 ANGIOPOIETIN TIE TEK 48545 0% 100% 1 Search ANGIOPOIETIN+TIE+TEK Search ANGIOPOIETIN+TIE+TEK
10 ANGIOTENSIN ANG 48545 0% 100% 1 Search ANGIOTENSIN+ANG Search ANGIOTENSIN+ANG

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 FORRESTER, SJ , KAWAI, T , O'BRIEN, S , THOMAS, W , HARRIS, RC , EGUCHI, S , (2016) EPIDERMAL GROWTH FACTOR RECEPTOR TRANSACTIVATION: MECHANISMS, PATHOPHYSIOLOGY, AND POTENTIAL THERAPIES IN THE CARDIOVASCULAR SYSTEM.ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 56. VOL. 56. ISSUE . P. 627 -653 38 23% 8
2 EGUCHI, S , FRANK, GD , MIFUNE, M , INAGAMI, T , (2003) METALLOPROTEASE-DEPENDENT ERBB LIGAND SHEDDING IN MEDIATING EGFR TRANSACTIVATION AND VASCULAR REMODELLING.BIOCHEMICAL SOCIETY TRANSACTIONS. VOL. 31. ISSUE . P. 1198-1202 30 58% 34
3 AZAR, ZM , MEHDI, MZ , SRIVASTAVA, AK , (2007) INSULIN-LIKE GROWTH FACTOR TYPE-1 RECEPTOR TRANSACTIVATION IN VASOACTIVE PEPTIDE AND OXIDANT-INDUCED SIGNALING PATHWAYS IN VASCULAR SMOOTH MUSCLE CELLS.CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY. VOL. 85. ISSUE 1. P. 105-111 26 60% 12
4 EGUCHI, S , INAGAMI, T , (2000) SIGNAL TRANSDUCTION OF ANGIOTENSIN II TYPE 1 RECEPTOR THROUGH RECEPTOR TYROSINE KINASE.REGULATORY PEPTIDES. VOL. 91. ISSUE 1-3. P. 13 -20 40 43% 102
5 FRANK, GD , EGUCHI, S , (2003) ACTIVATION OF TYROSINE KINASES BY REACTIVE OXYGEN SPECIES IN VASCULAR SMOOTH MUSCLE CELLS: SIGNIFICANCE AND INVOLVEMENT OF EGF RECEPTOR TRANSACTIVATION BY ANGIOTENSIN II.ANTIOXIDANTS & REDOX SIGNALING. VOL. 5. ISSUE 6. P. 771 -780 38 40% 44
6 ZAHRADKA, P , LITCHIE, B , STORIE, B , HELWER, G , (2004) TRANSACTIVATION OF THE INSULIN-LIKE GROWTH FACTOR-I RECEPTOR BY ANGIOTENSIN II MEDIATES DOWNSTREAM SIGNALING FROM THE ANGIOTENSIN II TYPE I RECEPTOR TO PHOSPHATIDYLINOSITOL 3-KINASE.ENDOCRINOLOGY. VOL. 145. ISSUE 6. P. 2978-2987 28 45% 43
7 HUGHES, AD , WIJETUNGE, S , (1998) ROLE OF TYROSINE PHOSPHORYLATION IN EXCITATION-CONTRACTION COUPLING IN VASCULAR SMOOTH MUSCLE.ACTA PHYSIOLOGICA SCANDINAVICA. VOL. 164. ISSUE 4. P. 457 -469 45 35% 28
8 FRANK, GD , SAITO, S , MOTLEY, ED , SASAKI, T , OHBA, M , KUROKI, T , INAGAMI, T , EGUCHI, S , (2002) REQUIREMENT OF CA2+ AND PKC DELTA FOR JANUS KINASE 2 ACTIVATION BY ANGIOTENSIN II: INVOLVEMENT OF PYK2.MOLECULAR ENDOCRINOLOGY. VOL. 16. ISSUE 2. P. 367 -377 28 47% 47
9 ALEXANDER, LD , DING, Y , ALAGARSAMY, S , CUI, XL , DOUGLAS, JG , (2006) ARACHIDONIC ACID INDUCES ERK ACTIVATION VIA SRC SH2 DOMAIN ASSOCIATION WITH THE EPIDERMAL GROWTH FACTOR RECEPTOR.KIDNEY INTERNATIONAL. VOL. 69. ISSUE 10. P. 1823-1832 20 61% 17
10 HIGUCHI, S , OHTSU, H , SUZUKI, H , SHIRAI, H , FRANK, GD , EGUCHI, S , (2007) ANGIOTENSIN II SIGNAL TRANSDUCTION THROUGH THE AT(I) RECEPTOR: NOVEL INSIG HTS INTO MECHANISMS AND PATHOPHYSIOLOGY.CLINICAL SCIENCE. VOL. 112. ISSUE 7-8. P. 417-428 32 28% 184

Classes with closest relation at Level 1


Rank Class id link
1 26062 LOE 908//G ALPHA12//VOLTAGE INDEPENDENT CALCIUM CHANNEL
2 9970 MAP KINASE KINASE//MAP KINASE//MAP KINASE ACTIVATOR
3 24850 TYRPHOSTIN//AG957//INOSTAMYCIN
4 2699 AT2 RECEPTOR//ANGIOTENSIN II RECEPTOR//ANGIOTENSIN RECEPTORS
5 29762 GONDA GOLD MIED VASC SURG//ATHEROSCLERSSIS//BARE METAL STENT IMPLANTATION
6 7520 MYOSIN PHOSPHATASE//CPI 17//MYPT1
7 13756 HB EGF//AMPHIREGULIN//HEPARIN BINDING EPIDERMAL GROWTH FACTOR LIKE GROWTH FACTOR
8 23729 MEMBRANE LIPID THERAPY//MOL CELLULAR BIOMED//MOL CELL BIOMED
9 22506 CARDIOTROPHIN 1//HSP 56//INTERLEUKIN 6 CYTOKINE FAMILY
10 2891 FOCAL ADHESION KINASE//FAK//PAXILLIN

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