Class information for:
Level 1: DYNORPHIN//DYNORPHIN A//KAPPA OPIOID RECEPTOR

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
3821 1900 33.4 68%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
11 4 NEUROSCIENCES//CLINICAL NEUROLOGY//NEUROL 1112395
440 3       NOCICEPTIN//OPIOID RECEPTORS//MORPHINE 26600
121 2             OPIOID RECEPTORS//MORPHINE//DELTA OPIOID RECEPTOR 24293
3821 1                   DYNORPHIN//DYNORPHIN A//KAPPA OPIOID RECEPTOR 1900

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 DYNORPHIN authKW 291221 6% 16% 116
2 DYNORPHIN A authKW 115947 1% 27% 27
3 KAPPA OPIOID RECEPTOR authKW 86249 3% 9% 58
4 CI 977 authKW 85699 0% 67% 8
5 KAPPA OPIOID authKW 80746 2% 17% 30
6 KAPPA OPIOID RECEPTOR AGONIST authKW 80543 1% 26% 19
7 E 2078 authKW 64278 0% 100% 4
8 NON OPIOID DYNORPHIN A authKW 64278 0% 100% 4
9 NEUROPEPTIDES journal 59505 5% 4% 97
10 KAPPA RECEPTORS authKW 56422 1% 29% 12

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Pharmacology & Pharmacy 12272 47% 0% 894
2 Neurosciences 6297 34% 0% 654
3 Endocrinology & Metabolism 1264 11% 0% 209
4 Medicine, Research & Experimental 1155 10% 0% 194
5 Chemistry, Medicinal 720 6% 0% 123
6 Anesthesiology 175 2% 0% 41
7 Physiology 108 4% 0% 69
8 Biochemistry & Molecular Biology 92 11% 0% 203
9 Biology 86 3% 0% 50
10 Behavioral Sciences 70 2% 0% 35

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SECT ALCOHOL DRUG DEPENDENCE 44705 0% 35% 8
2 GLOSTRUP HOSP ANESTHESIOL 32139 0% 100% 2
3 NEUROBIOL ANESTHESIOL BRANCH BLDG 30 ROOM B20 32139 0% 100% 2
4 EXPT ALCOHOL DRUG ADDICT SECT 22486 0% 20% 7
5 771 NARASHINODAI FUNABASHI SHI 16069 0% 100% 1
6 ALCOHOL DRUG DEPENDENCE SECT 16069 0% 100% 1
7 AREA NEUROCIENCIASIDIB S 16069 0% 100% 1
8 BMC ANALYT CHEM SCILIFE 16069 0% 100% 1
9 CHANDLER MED MS207 MED 16069 0% 100% 1
10 CHEM PHYSIOL ACT SUBSTANCES 16069 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 NEUROPEPTIDES 59505 5% 4% 97
2 LIFE SCIENCES 20554 8% 1% 161
3 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 16380 8% 1% 147
4 EUROPEAN JOURNAL OF PHARMACOLOGY 12576 8% 1% 149
5 BRAIN RESEARCH 5858 7% 0% 133
6 PEPTIDES 3815 2% 1% 46
7 ADVANCES IN PAIN RESEARCH AND THERAPY 3655 1% 2% 12
8 JOURNAL OF RECEPTOR RESEARCH 3325 1% 2% 11
9 BRITISH JOURNAL OF PHARMACOLOGY 2760 3% 0% 56
10 JOURNAL OF MEDICINAL CHEMISTRY 2432 3% 0% 58

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 DYNORPHIN 291221 6% 16% 116 Search DYNORPHIN Search DYNORPHIN
2 DYNORPHIN A 115947 1% 27% 27 Search DYNORPHIN+A Search DYNORPHIN+A
3 KAPPA OPIOID RECEPTOR 86249 3% 9% 58 Search KAPPA+OPIOID+RECEPTOR Search KAPPA+OPIOID+RECEPTOR
4 CI 977 85699 0% 67% 8 Search CI+977 Search CI+977
5 KAPPA OPIOID 80746 2% 17% 30 Search KAPPA+OPIOID Search KAPPA+OPIOID
6 KAPPA OPIOID RECEPTOR AGONIST 80543 1% 26% 19 Search KAPPA+OPIOID+RECEPTOR+AGONIST Search KAPPA+OPIOID+RECEPTOR+AGONIST
7 E 2078 64278 0% 100% 4 Search E+2078 Search E+2078
8 NON OPIOID DYNORPHIN A 64278 0% 100% 4 Search NON+OPIOID+DYNORPHIN+A Search NON+OPIOID+DYNORPHIN+A
9 KAPPA RECEPTORS 56422 1% 29% 12 Search KAPPA+RECEPTORS Search KAPPA+RECEPTORS
10 KAPPA OPIOID AGONIST 55235 1% 25% 14 Search KAPPA+OPIOID+AGONIST Search KAPPA+OPIOID+AGONIST

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 TAN-NO, K , TAKAHASHI, H , NAKAGAWASAI, O , NIIJIMA, F , SAKURADA, S , BAKALKIN, G , TERENIUS, L , TADANO, T , (2009) NOCICEPTIVE BEHAVIOR INDUCED BY THE ENDOGENOUS OPIOID PEPTIDES DYNORPHINS IN UNINJURED MICE: EVIDENCE WITH INTRATHECAL N-ETHYLMALEIMIDE INHIBITING DYNORPHIN DEGRADATION.ADVANCES IN NEUROPHARMACOLOGY. VOL. 85. ISSUE . P. 191-205 53 74% 3
2 HAUSER, KF , ALDRICH, JV , ANDERSON, KJ , BAKALKIN, G , CHRISTIE, MJ , HALL, ED , KNAPP, PE , SCHEFF, SW , SINGH, IN , VISSEL, B , ET AL (2005) PATHOBIOLOGY OF DYNORPHINS IN TRAUMA AND DISEASE.FRONTIERS IN BIOSCIENCE-LANDMARK. VOL. 10. ISSUE . P. 216-235 85 42% 46
3 HALL, SM , LEE, YS , HRUBY, VJ , (2016) DYNORPHIN A ANALOGS FOR THE TREATMENT OF CHRONIC NEUROPATHIC PAIN.FUTURE MEDICINAL CHEMISTRY. VOL. 8. ISSUE 2. P. 165 -177 54 51% 0
4 LAI, J , LUO, MC , CHEN, QM , PORRECA, F , (2008) PRONOCICEPTIVE ACTIONS OF DYNORPHIN VIA BRADYKININ RECEPTORS.NEUROSCIENCE LETTERS. VOL. 437. ISSUE 3. P. 175-179 42 76% 8
5 NAQVI, T , HAQ, W , MATHUR, KB , (1998) STRUCTURE-ACTIVITY RELATIONSHIP STUDIES OF DYNORPHIN A AND RELATED PEPTIDES.PEPTIDES. VOL. 19. ISSUE 7. P. 1277-1292 49 78% 29
6 BJORNERAS, J , GRASLUND, A , MAIER, L , (2013) MEMBRANE INTERACTION OF DISEASE-RELATED DYNORPHIN A VARIANTS.BIOCHEMISTRY. VOL. 52. ISSUE 24. P. 4157-4167 40 61% 5
7 LAUGHLIN, TM , LARSON, AA , WILCOX, GL , (2001) MECHANISMS OF INDUCTION OF PERSISTENT NOCICEPTION BY DYNORPHIN.JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. VOL. 299. ISSUE 1. P. 6-11 40 80% 52
8 SCHWARZER, C , (2009) 30 YEARS OF DYNORPHINS - NEW INSIGHTS ON THEIR FUNCTIONS IN NEUROPSYCHIATRIC DISEASES.PHARMACOLOGY & THERAPEUTICS. VOL. 123. ISSUE 3. P. 353 -370 76 28% 93
9 SHUKLA, VK , LEMAIRE, S , (1992) CENTRAL NONOPIOID PHYSIOLOGICAL AND PATHOPHYSIOLOGICAL EFFECTS OF DYNORPHIN-A AND RELATED PEPTIDES.JOURNAL OF PSYCHIATRY & NEUROSCIENCE. VOL. 17. ISSUE 3. P. 106-& 73 61% 12
10 GREENWALD, MK , STITZER, ML , HABERNY, KA , (1997) HUMAN PHARMACOLOGY OF THE OPIOID NEUROPEPTIDE DYNORPHIN A(1-13).JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. VOL. 281. ISSUE 3. P. 1154-1163 46 77% 14

Classes with closest relation at Level 1


Rank Class id link
1 17824 H 3ETORPHINE//H 3DIPRENORPHINE//SNPYS GROUP
2 1629 ENDOMORPHIN//DELTA OPIOID RECEPTOR//ENDOMORPHIN 2
3 13736 ELECTROSHOCK SEIZURE THRESHOLD//D ALA2 NME PHE4 GLYOL ENKEPHALIN DAMGO//FUNALTREXAMINE
4 12128 PROENKEPHALIN//MET ENKEPHALIN ARG6 PHE7//ENKEPHALIN PRECURSORS
5 6765 KAPPA OPIOID RECEPTOR//BIOL ADDICT DIS//DYNORPHIN
6 28500 3D NMR STRUCTURES//ACTH1 10//AMPHIPHILIC HELICAL PEPTIDE
7 6935 KEY DISCIPLINE CELL BIOL//MOL BIOL DRUG//U50 488H
8 28728 OHMEFENTANYL//FENTANYL ANALOGS//1 SUBSTITUTED ANALOGS
9 8912 BIPHALIN//DERMORPHIN//DERMORPHIN ANALOG
10 5552 MU OPIOID RECEPTOR//OPIOID RECEPTORS//OPIOID TOLERANCE

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