Class information for:
Level 1: HYBRIDIZATION CHAIN REACTION//ROLLING CIRCLE AMPLIFICATION//DNAZYME

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
4182 1832 38.5 92%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
5 4 CHEMISTRY, ORGANIC//CHEMISTRY, INORGANIC & NUCLEAR//CHEMISTRY, MULTIDISCIPLINARY 1745167
183 3       APTAMER//G QUADRUPLEX//RIBOZYME 56307
1286 2             APTAMER//SELEX//APTASENSOR 8682
4182 1                   HYBRIDIZATION CHAIN REACTION//ROLLING CIRCLE AMPLIFICATION//DNAZYME 1832

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 HYBRIDIZATION CHAIN REACTION authKW 511513 3% 57% 54
2 ROLLING CIRCLE AMPLIFICATION authKW 422825 4% 35% 73
3 DNAZYME authKW 373523 5% 22% 100
4 MICRORNA DETECTION authKW 278140 1% 76% 22
5 TERMINAL PROTECTION authKW 201181 1% 93% 13
6 PADLOCK PROBES authKW 191968 1% 48% 24
7 SIGNAL AMPLIFICATION authKW 159378 4% 14% 70
8 TARGET CATALYZED HAIRPIN ASSEMBLY authKW 149994 0% 100% 9
9 CLIN MOL MED DETECT address 149988 1% 75% 12
10 SENSOR ANAL TUMOR MARKER address 149940 2% 25% 36

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Chemistry, Analytical 24707 50% 0% 907
2 Electrochemistry 10238 20% 0% 372
3 Nanoscience & Nanotechnology 6498 21% 0% 378
4 Biophysics 3646 17% 0% 309
5 Biotechnology & Applied Microbiology 3238 19% 0% 344
6 Chemistry, Multidisciplinary 2891 27% 0% 500
7 Biochemical Research Methods 696 7% 0% 135
8 Biochemistry & Molecular Biology 152 12% 0% 225
9 Instruments & Instrumentation 28 2% 0% 39
10 Spectroscopy 24 2% 0% 31

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CLIN MOL MED DETECT 149988 1% 75% 12
2 SENSOR ANAL TUMOR MARKER 149940 2% 25% 36
3 SINGLE MOL DETECT IMAGING 89171 1% 31% 17
4 SHANDONG PROV DETECT TECHNOL TUMOR MAKERS 67488 0% 45% 9
5 FUJIAN PROV CANC METASTASIS CHEMOPREVENT 58324 0% 50% 7
6 STATE CHEMO BIOSENSING CHEMOMETR 58146 5% 4% 99
7 STATE ANALYT CHEM LIFE SCI 48354 3% 5% 59
8 BIOSYST MICROANAL 47192 1% 17% 17
9 BIONANOTECHNOL MOL ENGN HUNAN PROV 47106 1% 12% 23
10 QUAL SAFETY RISK ASSESSMENT CITRUS PROD CHO 46290 0% 56% 5

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOSENSORS & BIOELECTRONICS 147480 16% 3% 291
2 ANALYTICAL CHEMISTRY 21576 12% 1% 216
3 CHEMICAL COMMUNICATIONS 17458 12% 1% 212
4 ANALYST 11306 5% 1% 100
5 MICROCHIMICA ACTA 2174 1% 1% 20
6 ANALYTICAL METHODS 1838 1% 0% 26
7 ACS SENSORS 1826 0% 2% 5
8 ANALYTICA CHIMICA ACTA 1783 3% 0% 52
9 TALANTA 1611 2% 0% 41
10 CHEMICAL SCIENCE 1213 1% 0% 17

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 HYBRIDIZATION CHAIN REACTION 511513 3% 57% 54 Search HYBRIDIZATION+CHAIN+REACTION Search HYBRIDIZATION+CHAIN+REACTION
2 ROLLING CIRCLE AMPLIFICATION 422825 4% 35% 73 Search ROLLING+CIRCLE+AMPLIFICATION Search ROLLING+CIRCLE+AMPLIFICATION
3 DNAZYME 373523 5% 22% 100 Search DNAZYME Search DNAZYME
4 MICRORNA DETECTION 278140 1% 76% 22 Search MICRORNA+DETECTION Search MICRORNA+DETECTION
5 TERMINAL PROTECTION 201181 1% 93% 13 Search TERMINAL+PROTECTION Search TERMINAL+PROTECTION
6 PADLOCK PROBES 191968 1% 48% 24 Search PADLOCK+PROBES Search PADLOCK+PROBES
7 SIGNAL AMPLIFICATION 159378 4% 14% 70 Search SIGNAL+AMPLIFICATION Search SIGNAL+AMPLIFICATION
8 TARGET CATALYZED HAIRPIN ASSEMBLY 149994 0% 100% 9 Search TARGET+CATALYZED+HAIRPIN+ASSEMBLY Search TARGET+CATALYZED+HAIRPIN+ASSEMBLY
9 TARGET RECYCLING 129271 1% 48% 16 Search TARGET+RECYCLING Search TARGET+RECYCLING
10 DUPLEX SPECIFIC NUCLEASE 116648 1% 50% 14 Search DUPLEX+SPECIFIC+NUCLEASE Search DUPLEX+SPECIFIC+NUCLEASE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 ZHAO, YX , CHEN, F , LI, Q , WANG, LH , FAN, CH , (2015) ISOTHERMAL AMPLIFICATION OF NUCLEIC ACIDS.CHEMICAL REVIEWS. VOL. 115. ISSUE 22. P. 12491 -12545 235 36% 64
2 GRAYBILL, RM , BAILEY, RC , (2016) EMERGING BIOSENSING APPROACHES FOR MICRORNA ANALYSIS.ANALYTICAL CHEMISTRY. VOL. 88. ISSUE 1. P. 431 -450 100 65% 12
3 ALI, MM , LI, F , ZHANG, ZQ , ZHANG, KX , KANG, DK , ANKRUM, JA , LE, XC , ZHAO, WA , (2014) ROLLING CIRCLE AMPLIFICATION: A VERSATILE TOOL FOR CHEMICAL BIOLOGY, MATERIALS SCIENCE AND MEDICINE.CHEMICAL SOCIETY REVIEWS. VOL. 43. ISSUE 10. P. 3324-3341 75 51% 81
4 GERASIMOVA, YV , KOLPASHCHIKOV, DM , (2014) ENZYME-ASSISTED TARGET RECYCLING (EATR) FOR NUCLEIC ACID DETECTION.CHEMICAL SOCIETY REVIEWS. VOL. 43. ISSUE 17. P. 6405 -6438 86 48% 46
5 YAN, L , ZHOU, J , ZHENG, Y , GAMSON, AS , ROEMBKE, BT , NAKAYAMA, S , SINTIM, HO , (2014) ISOTHERMAL AMPLIFIED DETECTION OF DNA AND RNA.MOLECULAR BIOSYSTEMS. VOL. 10. ISSUE 5. P. 970 -1003 96 39% 66
6 OU, LJ , SUN, AM , LIU, KJ , (2015) ROLLING CIRCLE AMPLIFICATION-BASED BIOSENSORS.ANALYTICAL LETTERS. VOL. 48. ISSUE 8. P. 1199 -1216 67 74% 1
7 DEGLIANGELI, F , POMPA, PP , FIAMMENGO, R , (2014) NANOTECHNOLOGY-BASED STRATEGIES FOR THE DETECTION AND QUANTIFICATION OF MICRORNA.CHEMISTRY-A EUROPEAN JOURNAL. VOL. 20. ISSUE 31. P. 9476 -9492 78 60% 6
8 JOHNSON, BN , MUTHARASAN, R , (2014) BIOSENSOR-BASED MICRORNA DETECTION: TECHNIQUES, DESIGN, PERFORMANCE, AND CHALLENGES.ANALYST. VOL. 139. ISSUE 7. P. 1576-1588 72 53% 25
9 HUNT, EA , BROYLES, D , HEAD, T , DEO, SK , (2015) MICRORNA DETECTION: CURRENT TECHNOLOGY AND RESEARCH STRATEGIES.ANNUAL REVIEW OF ANALYTICAL CHEMISTRY, VOL 8. VOL. 8. ISSUE . P. 217 -237 60 61% 9
10 XIA, N , ZHANG, YJ , WEI, X , HUANG, YP , LIU, L , (2015) AN ELECTROCHEMICAL MICRORNAS BIOSENSOR WITH THE SIGNAL AMPLIFICATION OF ALKALINE PHOSPHATASE AND ELECTROCHEMICAL-CHEMICAL-CHEMICAL REDOX CYCLING.ANALYTICA CHIMICA ACTA. VOL. 878. ISSUE . P. 95 -101 43 77% 11

Classes with closest relation at Level 1


Rank Class id link
1 32849 TRANSCRIPTION FACTOR DETECTION//MOL IMAGING PROBES//CELL NUCLEAR EXTRACTS
2 6080 MERCURY ION//COLORIMETRIC DETECTION//MERCURYII ION
3 12480 MOLECULAR BEACON//IN VIVO HYBRIDIZATION//RNA IMAGING
4 24154 IMMUNO PCR//PROXIMITY LIGATION ASSAY//LEHRSTUHL BIOL CHEM MIKROSTRUKTURTECH
5 293 APTAMER//SELEX//APTASENSOR
6 2108 DNA ORIGAMI//DNA NANOTECHNOLOGY//DNA NANOSTRUCTURES
7 914 DNA BIOSENSOR//ELECTROCHEMICAL DNA BIOSENSOR//DNA HYBRIDIZATION
8 12071 LOOP MEDIATED ISOTHERMAL AMPLIFICATION//LAMP//LOOP MEDIATED ISOTHERMAL AMPLIFICATION LAMP
9 30665 PERSONAL GLUCOSE METER//SYNTH LIQUID CRYSTALS//PROTEIN ANTIBODY
10 21316 PHOTOELECTROCHEMICAL SENSOR//PHOTOELECTROCHEMICAL BIOSENSOR//PHOTOELECTROCHEMICAL IMMUNOASSAY

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