Class information for:
Level 1: AGMATINE//IMIDAZOLINE RECEPTORS//MOXONIDINE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
5229 1653 37.4 78%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
8 4 CARDIAC & CARDIOVASCULAR SYSTEM//PERIPHERAL VASCULAR DISEASES//CARDIOL 1276458
57 3       ANGIOTENSIN II//HYPERTENSION//PERIPHERAL VASCULAR DISEASES 89232
1516 2             DEXMEDETOMIDINE//AGMATINE//IMIDAZOLINE RECEPTORS 7504
5229 1                   AGMATINE//IMIDAZOLINE RECEPTORS//MOXONIDINE 1653

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 AGMATINE authKW 4525831 21% 72% 339
2 IMIDAZOLINE RECEPTORS authKW 3540193 14% 83% 230
3 MOXONIDINE authKW 2358855 10% 76% 168
4 RILMENIDINE authKW 1767489 7% 79% 121
5 IMIDAZOLINE BINDING SITES authKW 597092 2% 79% 41
6 I 1 IMIDAZOLINE RECEPTOR authKW 394042 1% 89% 24
7 IMIDAZOLINE I 2 RECEPTOR authKW 372494 1% 92% 22
8 H 3 IDAZOXAN authKW 370257 1% 95% 21
9 IMIDAZOLINE I 1 RECEPTOR authKW 317521 1% 90% 19
10 2 BFI authKW 314977 1% 95% 18

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Pharmacology & Pharmacy 12675 51% 0% 843
2 Neurosciences 2758 25% 0% 418
3 Peripheral Vascular Diseases 847 7% 0% 121
4 Cardiac & Cardiovascular System 527 8% 0% 136
5 Chemistry, Medicinal 252 4% 0% 73
6 Behavioral Sciences 175 3% 0% 46
7 Medicine, Research & Experimental 123 4% 0% 73
8 Biochemistry & Molecular Biology 112 12% 0% 192
9 Psychiatry 63 3% 0% 56
10 Physiology 47 3% 0% 48

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 NEUROBIOL PHARMACOL CARDIOVASC 306016 2% 53% 31
2 PHARMACOL CARDIOVASC RENALE 59106 0% 80% 4
3 PSYCHOPHARMACOL UNIT 55166 2% 7% 40
4 NURSING BIOTECHNOL 41558 0% 75% 3
5 CSIC NEUROPHARMACOL 36942 0% 100% 2
6 DRUG DEPENDENCE CHINA 36942 0% 100% 2
7 MEDPHARMACOL CARDIOVASC RENALE CNRS 36942 0% 100% 2
8 NEUROPHARMACOL ASSOCIATE UNITCSIC 36942 0% 100% 2
9 URA 589 36942 0% 100% 2
10 ASSOCIATE UNIT NEUROPHARMACOL 24627 0% 67% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 EUROPEAN JOURNAL OF PHARMACOLOGY 11877 8% 0% 135
2 NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 5579 3% 1% 43
3 JOURNAL OF CARDIOVASCULAR PHARMACOLOGY 5381 3% 1% 57
4 REVIEWS IN CONTEMPORARY PHARMACOTHERAPY 5179 0% 6% 5
5 BRITISH JOURNAL OF PHARMACOLOGY 5163 4% 0% 71
6 ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 4262 6% 0% 97
7 JOURNAL OF HYPERTENSION 3638 3% 0% 44
8 JOURNAL OF THE AUTONOMIC NERVOUS SYSTEM 2530 1% 1% 18
9 PHILOSOPHIA-INTERNATIONAL JOURNAL OF PHILOSOPHY 2307 0% 13% 1
10 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 2206 3% 0% 51

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 AGMATINE 4525831 21% 72% 339 Search AGMATINE Search AGMATINE
2 IMIDAZOLINE RECEPTORS 3540193 14% 83% 230 Search IMIDAZOLINE+RECEPTORS Search IMIDAZOLINE+RECEPTORS
3 MOXONIDINE 2358855 10% 76% 168 Search MOXONIDINE Search MOXONIDINE
4 RILMENIDINE 1767489 7% 79% 121 Search RILMENIDINE Search RILMENIDINE
5 IMIDAZOLINE BINDING SITES 597092 2% 79% 41 Search IMIDAZOLINE+BINDING+SITES Search IMIDAZOLINE+BINDING+SITES
6 I 1 IMIDAZOLINE RECEPTOR 394042 1% 89% 24 Search I+1+IMIDAZOLINE+RECEPTOR Search I+1+IMIDAZOLINE+RECEPTOR
7 IMIDAZOLINE I 2 RECEPTOR 372494 1% 92% 22 Search IMIDAZOLINE+I+2+RECEPTOR Search IMIDAZOLINE+I+2+RECEPTOR
8 H 3 IDAZOXAN 370257 1% 95% 21 Search H+3+IDAZOXAN Search H+3+IDAZOXAN
9 IMIDAZOLINE I 1 RECEPTOR 317521 1% 90% 19 Search IMIDAZOLINE+I+1+RECEPTOR Search IMIDAZOLINE+I+1+RECEPTOR
10 2 BFI 314977 1% 95% 18 Search 2+BFI Search 2+BFI

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 MOLDERINGS, GJ , HAENISCH, B , (2012) AGMATINE (DECARBOXYLATED L-ARGININE): PHYSIOLOGICAL ROLE AND THERAPEUTIC POTENTIAL.PHARMACOLOGY & THERAPEUTICS. VOL. 133. ISSUE 3. P. 351 -365 215 86% 35
2 PILETZ, JE , ARICIOGLU, F , CHENG, JT , FAIRBANKS, CA , GILAD, VH , HAENISCH, B , HALARIS, A , HONG, S , LEE, JE , LI, J , ET AL (2013) AGMATINE: CLINICAL APPLICATIONS AFTER 100 YEARS IN TRANSLATION.DRUG DISCOVERY TODAY. VOL. 18. ISSUE 17-18. P. 880 -893 105 90% 35
3 RAASCH, W , SCHAFER, U , CHUN, J , DOMINIAK, P , (2001) BIOLOGICAL SIGNIFICANCE OF AGMATINE, AN ENDOGENOUS LIGAND AT IMIDAZOLINE BINDING SITES.BRITISH JOURNAL OF PHARMACOLOGY. VOL. 133. ISSUE 6. P. 755-780 163 68% 120
4 FARSANG, C , KAPOCSI, J , (1999) IMIDAZOLINE RECEPTORS: FROM DISCOVERY TO ANTIHYPERTENSIVE THERAPY (FACTS AND DOUBTS).BRAIN RESEARCH BULLETIN. VOL. 49. ISSUE 5. P. 317 -331 151 79% 38
5 NIKOLIC, K , AGBABA, D , (2012) PHARMACOPHORE DEVELOPMENT AND SAR STUDIES OF IMIDAZOLINE RECEPTOR LIGANDS.MINI-REVIEWS IN MEDICINAL CHEMISTRY. VOL. 12. ISSUE 14. P. 1542-1555 102 77% 10
6 HALARIS, A , PLIETZ, J , (2007) AGMATINE: METABOLIC PATHWAY AND SPECTRUM OF ACTIVITY IN BRAIN.CNS DRUGS. VOL. 21. ISSUE 11. P. 885 -900 80 89% 123
7 KELLER, B , GARCIA-SEVILLA, JA , (2015) IMMUNODETECTION AND SUBCELLULAR DISTRIBUTION OF IMIDAZOLINE RECEPTOR PROTEINS WITH THREE ANTIBODIES IN MOUSE AND HUMAN BRAINS: EFFECTS OF TREATMENTS WITH I-1- AND I-2-IMIDAZOLINE DRUGS.JOURNAL OF PSYCHOPHARMACOLOGY. VOL. 29. ISSUE 9. P. 996 -1012 72 91% 1
8 NIKOLIC, K , AGBABA, D , (2012) IMIDAZOLINE RECEPTORS LIGANDS.HEMIJSKA INDUSTRIJA. VOL. 66. ISSUE 5. P. 619-635 92 77% 0
9 REGUNATHAN, S , REIS, DJ , (1996) IMIDAZOLINE RECEPTORS AND THEIR ENDOGENOUS LIGANDS.ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY. VOL. 36. ISSUE . P. 511-544 110 80% 171
10 NIKOLIC, K , AGBABA, D , (2012) IMIDAZOLINE ANTIHYPERTENSIVE DRUGS: SELECTIVE I1-IMIDAZOLINE RECEPTORS ACTIVATION.CARDIOVASCULAR THERAPEUTICS. VOL. 30. ISSUE 4. P. 209-216 75 86% 14

Classes with closest relation at Level 1


Rank Class id link
1 20381 EFAROXAN//CELLULAR PHARMACOL GRP//IMIDAZOLINE
2 9490 ALPHA2 ADRENOCEPTOR SUBTYPES//ALPHA2C ADRENOCEPTOR//ALPHA2A ADRENOCEPTOR
3 34070 TETRAHYDROZOLINE//CLONIDINE TOXICITY//ABT ANASTHESIE PRIOPERAT INTENS MED
4 15714 ARTERIAL PRESSURE RELATED NEURON//NOCICEPTION RELATED NEURON//NUCLEUS RETICULARIS GIGANTOCELLULARIS
5 5208 JOURNAL OF AUTONOMIC PHARMACOLOGY//POSTJUNCTIONAL ALPHA 2 ADRENOCEPTORS//POSTJUNCTIONAL ALPHA 1 ADRENOCEPTORS
6 8908 AFFERENT RENAL NERVES//AFFERENT RENAL NERVE ACTIVITY//RENAL CHEMORECEPTORS
7 2592 ROSTRAL VENTROLATERAL MEDULLA//CAUDAL VENTROLATERAL MEDULLA//VENTROLATERAL MEDULLA
8 31461 5 HYDROXYINDOLE ACETIC ACID CLEARANCE//ACUTE SAMPLING//ALZHEIMERS GAMMA SECRETASE
9 29985 CATEDRA QUIM GEN//CATEDRA FISICOQUIM 1//COORDINATION BIDENTATE
10 2793 DEXMEDETOMIDINE//CLONIDINE//ALPHA2 ADRENOCEPTOR AGONIST

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