Class information for:
Level 2: DEXMEDETOMIDINE//AGMATINE//IMIDAZOLINE RECEPTORS

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
1516 7504 37.8 71%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
8 4 CARDIAC & CARDIOVASCULAR SYSTEM//PERIPHERAL VASCULAR DISEASES//CARDIOL 1276458
57 3       ANGIOTENSIN II//HYPERTENSION//PERIPHERAL VASCULAR DISEASES 89232
1516 2             DEXMEDETOMIDINE//AGMATINE//IMIDAZOLINE RECEPTORS 7504
2793 1                   DEXMEDETOMIDINE//CLONIDINE//ALPHA2 ADRENOCEPTOR AGONIST 2147
5229 1                   AGMATINE//IMIDAZOLINE RECEPTORS//MOXONIDINE 1653
9490 1                   ALPHA2 ADRENOCEPTOR SUBTYPES//ALPHA2C ADRENOCEPTOR//ALPHA2A ADRENOCEPTOR 1151
9827 1                   GUANFACINE//LOCUS COERULEUS//NORADRENERGIC AXON 1117
15714 1                   ARTERIAL PRESSURE RELATED NEURON//NOCICEPTION RELATED NEURON//NUCLEUS RETICULARIS GIGANTOCELLULARIS 696
16972 1                   DSP 4//DSP 4 N 2 CHLOROETHYL N ETHYL 2 BROMOBENZYLAMINE//LOCUS COERULEUS 624
34070 1                   TETRAHYDROZOLINE//CLONIDINE TOXICITY//ABT ANASTHESIE PRIOPERAT INTENS MED 116

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 DEXMEDETOMIDINE authKW 2033327 11% 62% 810
2 AGMATINE authKW 996433 5% 72% 339
3 IMIDAZOLINE RECEPTORS authKW 820696 3% 86% 236
4 MOXONIDINE authKW 525556 2% 76% 169
5 ALPHA2 ADRENOCEPTOR authKW 474270 5% 33% 358
6 CLONIDINE authKW 438784 6% 24% 446
7 RILMENIDINE authKW 415321 2% 82% 125
8 ALPHA2 ADRENOCEPTOR SUBTYPES authKW 226576 1% 90% 62
9 ALPHA2 ADRENERGIC RECEPTOR authKW 158675 2% 35% 113
10 IDAZOXAN authKW 150420 1% 39% 96

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Anesthesiology 45207 15% 1% 1121
2 Pharmacology & Pharmacy 23274 34% 0% 2516
3 Neurosciences 18802 30% 0% 2275
4 Behavioral Sciences 1123 3% 0% 241
5 Critical Care Medicine 515 2% 0% 148
6 Peripheral Vascular Diseases 479 3% 0% 234
7 Medicine, Research & Experimental 430 4% 0% 303
8 Cardiac & Cardiovascular System 410 4% 0% 319
9 Psychiatry 334 4% 0% 267
10 Physiology 245 3% 0% 227

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 NEUROBIOL PHARMACOL CARDIOVASC 67362 0% 53% 31
2 ANESTHESIOL 23363 8% 1% 603
3 ORION PHARMA 16801 0% 15% 27
4 PSYCHOPHARMACOL UNIT 16003 1% 9% 46
5 HYPERTENS ATHEROSCLEROSIS SECT 14301 0% 27% 13
6 NW NETWORK MENTAL ILLNESS EDUC CLIN 13279 0% 47% 7
7 PHARMACOL CARDIOVASC RENALE 13014 0% 80% 4
8 UNIT 388 13014 0% 80% 4
9 PHARMACOL CLIN PHARMACOL 12752 1% 5% 69
10 PHARMACOL DRUG DEV THER EUT 12432 0% 10% 31

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 EUROPEAN JOURNAL OF PHARMACOLOGY 15620 4% 1% 333
2 ANESTHESIA AND ANALGESIA 15059 3% 2% 235
3 ANESTHESIOLOGY 13755 3% 2% 197
4 PEDIATRIC ANESTHESIA 9935 1% 3% 72
5 NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 8392 2% 2% 113
6 BRAIN RESEARCH 6606 4% 1% 286
7 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 6392 2% 1% 186
8 BRITISH JOURNAL OF PHARMACOLOGY 6286 2% 1% 169
9 JOURNAL OF ANESTHESIA 5198 1% 3% 43
10 JOURNAL OF CLINICAL ANESTHESIA 4877 1% 2% 56

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 DEXMEDETOMIDINE 2033327 11% 62% 810 Search DEXMEDETOMIDINE Search DEXMEDETOMIDINE
2 AGMATINE 996433 5% 72% 339 Search AGMATINE Search AGMATINE
3 IMIDAZOLINE RECEPTORS 820696 3% 86% 236 Search IMIDAZOLINE+RECEPTORS Search IMIDAZOLINE+RECEPTORS
4 MOXONIDINE 525556 2% 76% 169 Search MOXONIDINE Search MOXONIDINE
5 ALPHA2 ADRENOCEPTOR 474270 5% 33% 358 Search ALPHA2+ADRENOCEPTOR Search ALPHA2+ADRENOCEPTOR
6 CLONIDINE 438784 6% 24% 446 Search CLONIDINE Search CLONIDINE
7 RILMENIDINE 415321 2% 82% 125 Search RILMENIDINE Search RILMENIDINE
8 ALPHA2 ADRENOCEPTOR SUBTYPES 226576 1% 90% 62 Search ALPHA2+ADRENOCEPTOR+SUBTYPES Search ALPHA2+ADRENOCEPTOR+SUBTYPES
9 ALPHA2 ADRENERGIC RECEPTOR 158675 2% 35% 113 Search ALPHA2+ADRENERGIC+RECEPTOR Search ALPHA2+ADRENERGIC+RECEPTOR
10 IDAZOXAN 150420 1% 39% 96 Search IDAZOXAN Search IDAZOXAN

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 MOLDERINGS, GJ , HAENISCH, B , (2012) AGMATINE (DECARBOXYLATED L-ARGININE): PHYSIOLOGICAL ROLE AND THERAPEUTIC POTENTIAL.PHARMACOLOGY & THERAPEUTICS. VOL. 133. ISSUE 3. P. 351 -365 215 86% 35
2 PILETZ, JE , ARICIOGLU, F , CHENG, JT , FAIRBANKS, CA , GILAD, VH , HAENISCH, B , HALARIS, A , HONG, S , LEE, JE , LI, J , ET AL (2013) AGMATINE: CLINICAL APPLICATIONS AFTER 100 YEARS IN TRANSLATION.DRUG DISCOVERY TODAY. VOL. 18. ISSUE 17-18. P. 880 -893 105 90% 35
3 RAASCH, W , SCHAFER, U , CHUN, J , DOMINIAK, P , (2001) BIOLOGICAL SIGNIFICANCE OF AGMATINE, AN ENDOGENOUS LIGAND AT IMIDAZOLINE BINDING SITES.BRITISH JOURNAL OF PHARMACOLOGY. VOL. 133. ISSUE 6. P. 755-780 171 72% 120
4 SZABO, B , (2002) IMIDAZOLINE ANTIHYPERTENSIVE DRUGS: A CRITICAL REVIEW ON THEIR MECHANISM OF ACTION.PHARMACOLOGY & THERAPEUTICS. VOL. 93. ISSUE 1. P. 1 -35 159 71% 83
5 LOWRY, JA , BROWN, JT , (2014) SIGNIFICANCE OF THE IMIDAZOLINE RECEPTORS IN TOXICOLOGY.CLINICAL TOXICOLOGY. VOL. 52. ISSUE 5. P. 454 -469 107 80% 5
6 FARSANG, C , KAPOCSI, J , (1999) IMIDAZOLINE RECEPTORS: FROM DISCOVERY TO ANTIHYPERTENSIVE THERAPY (FACTS AND DOUBTS).BRAIN RESEARCH BULLETIN. VOL. 49. ISSUE 5. P. 317 -331 156 82% 38
7 MASON, KP , LERMAN, J , (2011) DEXMEDETOMIDINE IN CHILDREN: CURRENT KNOWLEDGE AND FUTURE APPLICATIONS.ANESTHESIA AND ANALGESIA. VOL. 113. ISSUE 5. P. 1129-1142 101 77% 55
8 NIKOLIC, K , AGBABA, D , (2012) PHARMACOPHORE DEVELOPMENT AND SAR STUDIES OF IMIDAZOLINE RECEPTOR LIGANDS.MINI-REVIEWS IN MEDICINAL CHEMISTRY. VOL. 12. ISSUE 14. P. 1542-1555 105 80% 10
9 MAHMOUD, M , MASON, KP , (2015) DEXMEDETOMIDINE: REVIEW, UPDATE, AND FUTURE CONSIDERATIONS OF PAEDIATRIC PERIOPERATIVE AND PERIPROCEDURAL APPLICATIONS AND LIMITATIONS.BRITISH JOURNAL OF ANAESTHESIA. VOL. 115. ISSUE 2. P. 171 -182 85 75% 16
10 ERNSBERGER, P , (1998) THE I-1-IMIDAZOLINE RECEPTOR AGONIST MOXONIDINE: MOLECULAR, CELLULAR AND ORGANISMIC ACTIONS.REVIEWS IN CONTEMPORARY PHARMACOTHERAPY. VOL. 9. ISSUE 7. P. 441 -462 147 83% 6

Classes with closest relation at Level 2


Rank Class id link
1 1243 NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY//JOURNAL OF AUTONOMIC PHARMACOLOGY//BLOOD VESSELS
2 1858 VETERINARY ANAESTHESIA AND ANALGESIA//MEDETOMIDINE//XYLAZINE
3 1343 ROSTRAL VENTROLATERAL MEDULLA//CAUDAL VENTROLATERAL MEDULLA//BARORECEPTORS
4 1912 SEDATION//KETAMINE//MIDAZOLAM
5 2253 RENAL DENERVATION//RESISTANT HYPERTENSION//RENAL SYMPATHETIC DENERVATION
6 3567 BEZOAR//TRICHOBEZOAR//PHYTOBEZOAR
7 218 SEROTONIN//5 HT1A RECEPTOR//5 HT2A RECEPTOR
8 272 ANESTHESIOLOGY//PROPOFOL//SEVOFLURANE
9 3441 PUPILLOMETRY//HORNERS SYNDROME//PUPIL
10 1615 DELIRIUM//POSTOPERATIVE DELIRIUM//CRITICAL ILLNESS POLYNEUROPATHY

Go to start page