Class information for:
Level 1: MLL//MLL GENE//11Q23

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
5973 1549 40.9 89%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
51 3       HEMATOLOGY//BONE MARROW TRANSPLANTATION//BLOOD 91443
56 2             MYELODYSPLASTIC SYNDROME//HEMATOLOGY//ACUTE MYELOID LEUKEMIA 29625
5973 1                   MLL//MLL GENE//11Q23 1549

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MLL authKW 1919497 12% 54% 179
2 MLL GENE authKW 553274 3% 70% 40
3 11Q23 authKW 406870 2% 61% 34
4 DOT1L authKW 270305 2% 57% 24
5 INFANT LEUKEMIA authKW 208777 2% 42% 25
6 T411 authKW 198753 1% 92% 11
7 DCAL address 194068 1% 62% 16
8 CALM AF10 authKW 183463 1% 85% 11
9 11Q23 TRANSLOCATION authKW 166551 1% 65% 13
10 MLL REARRANGEMENT authKW 162741 1% 49% 17

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Hematology 24631 38% 0% 596
2 Oncology 14571 50% 0% 776
3 Genetics & Heredity 5766 26% 0% 403
4 Cell Biology 1840 19% 0% 295
5 Biochemistry & Molecular Biology 476 19% 0% 287
6 Developmental Biology 64 2% 0% 26
7 Medicine, Research & Experimental 28 3% 0% 44
8 Pediatrics 27 3% 0% 39
9 Cell & Tissue Engineering 24 0% 0% 7
10 Pathology 17 2% 0% 26

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 DCAL 194068 1% 62% 16
2 DIAGNOST ACUTE LEUKEMIA 141911 1% 60% 12
3 PHARMACEUT BIOL ZAFES 78845 0% 100% 4
4 LEONARD MADLYN ABRAMSON PEDIAT 70956 0% 60% 6
5 NIHR OXFORD BIOMED PROGRAMME 59134 0% 100% 3
6 ZAFESBIO 44349 0% 75% 3
7 CANC UK LEUKAEMIA BIOL GRP 39423 0% 100% 2
8 MOL BIOL HLA TYPING UNIT 39423 0% 100% 2
9 MOL ONCOL PROGRAM MED 39423 0% 100% 2
10 ZAFESDCAL 39423 0% 100% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CANCER GENETICS AND CYTOGENETICS 63353 9% 2% 140
2 LEUKEMIA 60351 10% 2% 152
3 GENES CHROMOSOMES & CANCER 50351 6% 3% 90
4 BLOOD 13688 10% 0% 155
5 CANCER CELL 7393 2% 2% 24
6 LEUKEMIA RESEARCH 3944 2% 1% 35
7 CANCER GENETICS 3848 1% 2% 9
8 INTERNATIONAL JOURNAL OF HEMATOLOGY 3230 2% 1% 25
9 ONCOGENE 3226 4% 0% 55
10 BRITISH JOURNAL OF HAEMATOLOGY 2518 3% 0% 42

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 MLL 1919497 12% 54% 179 Search MLL Search MLL
2 MLL GENE 553274 3% 70% 40 Search MLL+GENE Search MLL+GENE
3 11Q23 406870 2% 61% 34 Search 11Q23 Search 11Q23
4 DOT1L 270305 2% 57% 24 Search DOT1L Search DOT1L
5 INFANT LEUKEMIA 208777 2% 42% 25 Search INFANT+LEUKEMIA Search INFANT+LEUKEMIA
6 T411 198753 1% 92% 11 Search T411 Search T411
7 CALM AF10 183463 1% 85% 11 Search CALM+AF10 Search CALM+AF10
8 11Q23 TRANSLOCATION 166551 1% 65% 13 Search 11Q23+TRANSLOCATION Search 11Q23+TRANSLOCATION
9 MLL REARRANGEMENT 162741 1% 49% 17 Search MLL+REARRANGEMENT Search MLL+REARRANGEMENT
10 AF10 158619 1% 62% 13 Search AF10 Search AF10

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 WINTERS, AC , BERNT, KM , (2017) MLL-REARRANGED LEUKEMIAS-AN UPDATE ON SCIENCE AND CLINICAL APPROACHES.FRONTIERS IN PEDIATRICS. VOL. 5. ISSUE . P. - 124 57% 0
2 CHEN, CW , ARMSTRONG, SA , (2015) TARGETING DOT1L AND HOX GENE EXPRESSION IN MLL-REARRANGED LEUKEMIA AND BEYOND.EXPERIMENTAL HEMATOLOGY. VOL. 43. ISSUE 8. P. 673 -684 90 59% 16
3 MUNTEAN, AG , HESS, JL , (2012) THE PATHOGENESIS OF MIXED-LINEAGE LEUKEMIA.ANNUAL REVIEW OF PATHOLOGY: MECHANISMS OF DISEASE, VOL 7. VOL. 7. ISSUE . P. 283 -301 72 68% 100
4 MITTERBAUER-HOHENDANNER, G , MANNHALTER, C , (2004) THE BIOLOGICAL AND CLINICAL SIGNIFICANCE OF MLL ABNORMALITIES IN HAEMATOLOGICAL MALIGNANCIES.EUROPEAN JOURNAL OF CLINICAL INVESTIGATION. VOL. 34. ISSUE . P. 12-24 104 78% 20
5 SLANY, RK , (2009) THE MOLECULAR BIOLOGY OF MIXED LINEAGE LEUKEMIA.HAEMATOLOGICA-THE HEMATOLOGY JOURNAL. VOL. 94. ISSUE 7. P. 984 -993 77 66% 141
6 KRIVTSOV, AV , ARMSTRONG, SA , (2007) MLL TRANSLOCATIONS, HISTONE MODIFICATIONS AND LEUKAEMIA STEM-CELL DEVELOPMENT.NATURE REVIEWS CANCER. VOL. 7. ISSUE 11. P. 823 -833 68 59% 476
7 LIU, H , CHENG, EHY , HSIEH, JJD , (2009) MLL FUSIONS PATHWAYS TO LEUKEMIA.CANCER BIOLOGY & THERAPY. VOL. 8. ISSUE 13. P. 1204 -1211 83 73% 46
8 YOKOYAMA, A , (2015) MOLECULAR MECHANISMS OF MLL-ASSOCIATED LEUKEMIA.INTERNATIONAL JOURNAL OF HEMATOLOGY. VOL. 101. ISSUE 4. P. 352 -361 71 75% 5
9 YIP, BH , SO, CWE , (2013) MIXED LINEAGE LEUKEMIA PROTEIN IN NORMAL AND LEUKEMIC STEM CELLS.EXPERIMENTAL BIOLOGY AND MEDICINE. VOL. 238. ISSUE 3. P. 315 -323 69 78% 3
10 DAIGLE, SR , OLHAVA, EJ , THERKELSEN, CA , BASAVAPATHRUNI, A , JIN, L , BORIACK-SJODIN, PA , ALLAIN, CJ , KLAUS, CR , RAIMONDI, A , SCOTT, MP , ET AL (2013) POTENT INHIBITION OF DOT1L AS TREATMENT OF MLL-FUSION LEUKEMIA.BLOOD. VOL. 122. ISSUE 6. P. 1017-1025 35 85% 167

Classes with closest relation at Level 1


Rank Class id link
1 7627 TEL AML1//TEL//ETV6
2 14125 USP22//SET1//UBIQUITIN SPECIFIC PROTEASE 22
3 8127 SECONDARY LEUKEMIA//THERAPY RELATED//THERAPY RELATED LEUKEMIA
4 8103 PBX//HOXB7//HOX
5 30263 ANTI I MONOCLONAL ANTIBODY//CHINESE HAMSTER OVARY CRICETULUS//CHROMOSOME EXTRACOPYING
6 6990 ACUTE LYMPHOBLASTIC LEUKEMIA//TESTICULAR RELAPSE//TESTICULAR LEUKEMIA
7 25496 AML IN CHILDREN//BFM AML GRP//HONG KONG PAEDIAT HAEMATOL ONCOL STUDY GRP
8 4828 RUNX3//AML1 ETO//RUNX1
9 9898 TRANSIENT MYELOPROLIFERATIVE DISORDER//TRANSIENT ABNORMAL MYELOPOIESIS//ACUTE MEGAKARYOBLASTIC LEUKEMIA
10 552 ACUTE MYELOID LEUKEMIA//FLT3//FLT3 ITD

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