Class information for:
Level 1: USP22//SET1//UBIQUITIN SPECIFIC PROTEASE 22

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
14125 791 53.1 96%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
71 3       GENETICS & HEREDITY//CHROMATIN//CELL BIOLOGY 83302
343 2             EZH2//CHROMATIN//POLYCOMB 17754
14125 1                   USP22//SET1//UBIQUITIN SPECIFIC PROTEASE 22 791

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 USP22 authKW 992616 4% 86% 30
2 SET1 authKW 441149 3% 57% 20
3 UBIQUITIN SPECIFIC PROTEASE 22 authKW 274502 1% 89% 8
4 MLL3 authKW 240515 1% 69% 9
5 WDR5 authKW 222411 1% 52% 11
6 ASH2L authKW 210164 1% 78% 7
7 SET2 authKW 205872 1% 67% 8
8 PAF1 COMPLEX authKW 175453 1% 45% 10
9 H2B UBIQUITYLATION authKW 173706 1% 75% 6
10 RNF20 authKW 171950 1% 64% 7

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Cell Biology 6464 46% 0% 365
2 Biochemistry & Molecular Biology 4548 62% 0% 489
3 Genetics & Heredity 1260 18% 0% 139
4 Developmental Biology 795 7% 0% 53
5 Biophysics 240 7% 0% 58
6 Oncology 169 10% 0% 76
7 Mycology 35 1% 0% 8
8 Biochemical Research Methods 9 2% 0% 17
9 Biology 8 2% 0% 13
10 Biotechnology & Applied Microbiology 4 3% 0% 20

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PROGRAM EPIGENET MOL CARCINOGENESIS 154408 1% 100% 4
2 SECT PEDIAT HEMATOL ONCOL PEDIAT 74229 1% 38% 5
3 GENE REGULAT DIS 51468 0% 67% 2
4 ST LOUIS UNIV CANC 51468 0% 67% 2
5 URPHYM GEMO 51468 0% 67% 2
6 ANIM ISTENCE SHANDONG PROV 38602 0% 100% 1
7 BIOCHEMROBERT WOOD JOHNSON MED 38602 0% 100% 1
8 BIOLNNOVATZENTRUM 38602 0% 100% 1
9 CANC SECT PEDIAT HEMATOL ONCOL 38602 0% 100% 1
10 CANC TREATMENTONCOGENOM 38602 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MOLECULAR CELL 19846 7% 1% 53
2 MOLECULAR AND CELLULAR BIOLOGY 5786 7% 0% 58
3 GENES & DEVELOPMENT 5275 4% 0% 32
4 BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS 2969 1% 1% 9
5 NATURE STRUCTURAL & MOLECULAR BIOLOGY 2552 2% 1% 12
6 EPIGENETICS & CHROMATIN 2129 1% 1% 4
7 CELL REPORTS 1414 1% 0% 11
8 EPIGENETICS 1351 0% 1% 3
9 JOURNAL OF BIOLOGICAL CHEMISTRY 1234 9% 0% 72
10 CIBA FOUNDATION SYMPOSIA 1134 1% 0% 9

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 USP22 992616 4% 86% 30 Search USP22 Search USP22
2 SET1 441149 3% 57% 20 Search SET1 Search SET1
3 UBIQUITIN SPECIFIC PROTEASE 22 274502 1% 89% 8 Search UBIQUITIN+SPECIFIC+PROTEASE+22 Search UBIQUITIN+SPECIFIC+PROTEASE+22
4 MLL3 240515 1% 69% 9 Search MLL3 Search MLL3
5 WDR5 222411 1% 52% 11 Search WDR5 Search WDR5
6 ASH2L 210164 1% 78% 7 Search ASH2L Search ASH2L
7 SET2 205872 1% 67% 8 Search SET2 Search SET2
8 PAF1 COMPLEX 175453 1% 45% 10 Search PAF1+COMPLEX Search PAF1+COMPLEX
9 H2B UBIQUITYLATION 173706 1% 75% 6 Search H2B+UBIQUITYLATION Search H2B+UBIQUITYLATION
10 RNF20 171950 1% 64% 7 Search RNF20 Search RNF20

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 TOMSON, BN , ARNDT, KM , (2013) THE MANY ROLES OF THE CONSERVED EUKARYOTIC PAF1 COMPLEX IN REGULATING TRANSCRIPTION, HISTONE MODIFICATIONS, AND DISEASE STATES.BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS. VOL. 1829. ISSUE 1. P. 116-126 80 46% 38
2 SHILATIFARD, A , (2012) THE COMPASS FAMILY OF HISTONE H3K4 METHYLASES: MECHANISMS OF REGULATION IN DEVELOPMENT AND DISEASE PATHOGENESIS.ANNUAL REVIEW OF BIOCHEMISTRY, VOL 81. VOL. 81. ISSUE . P. 65 -95 66 36% 215
3 PIRO, AS , MAYEKAR, MK , WARNER, MH , DAVIS, CP , ARNDT, KM , (2012) SMALL REGION OF RTF1 PROTEIN CAN SUBSTITUTE FOR COMPLETE PAF1 COMPLEX IN FACILITATING GLOBAL HISTONE H2B UBIQUITYLATION IN YEAST.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. VOL. 109. ISSUE 27. P. 10837-10842 45 82% 14
4 KIM, J , KIM, JA , MCGINTY, RK , NGUYEN, UTT , MUIR, TW , ALLIS, CD , ROEDER, RG , (2013) THE N-SET DOMAIN OF SET1 REGULATES H2B UBIQUITYLATION-DEPENDENT H3K4 METHYLATION.MOLECULAR CELL. VOL. 49. ISSUE 6. P. 1121-1133 33 94% 25
5 CUCINOTTA, CE , YOUNG, AN , KLUCEVSEK, KM , ARNDT, KM , (2015) THE NUCLEOSOME ACIDIC PATCH REGULATES THE H2B K123 MONOUBIQUITYLATION CASCADE AND TRANSCRIPTION ELONGATION IN SACCHAROMYCES CEREVISIAE.PLOS GENETICS. VOL. 11. ISSUE 8. P. - 46 59% 8
6 RAO, RC , DOU, YL , (2015) HIJACKED IN CANCER: THE KMT2 (MLL) FAMILY OF METHYLTRANSFERASES.NATURE REVIEWS CANCER. VOL. 15. ISSUE 6. P. 334 -346 63 33% 29
7 COLE, AJ , CLIFTON-BLIGH, R , MARSH, DJ , (2015) HISTONE H2B MONOUBIQUITINATION: ROLES TO PLAY IN HUMAN MALIGNANCY.ENDOCRINE-RELATED CANCER. VOL. 22. ISSUE 1. P. T19 -T33 58 44% 10
8 MERSMAN, DP , DU, HN , FINGERMAN, IM , SOUTH, PF , BRIGGS, SD , (2012) CHARGE-BASED INTERACTION CONSERVED WITHIN HISTONE H3 LYSINE 4 (H3K4) METHYLTRANSFERASE COMPLEXES IS NEEDED FOR PROTEIN STABILITY, HISTONE METHYLATION, AND GENE EXPRESSION.JOURNAL OF BIOLOGICAL CHEMISTRY. VOL. 287. ISSUE 4. P. 2652-2665 36 84% 14
9 FUCHS, G , OREN, M , (2014) WRITING AND READING H2B MONOUBIQUITYLATION.BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS. VOL. 1839. ISSUE 8. P. 694 -701 50 51% 18
10 VAN OSS, SB , SHIRRA, MK , BATAILLE, AR , WIER, AD , YEN, KY , VINAYACHANDRAN, V , BYEON, IJL , CUCINOTTA, CE , HEROUX, A , JEON, J , ET AL (2016) THE HISTONE MODIFICATION DOMAIN OF PAF1 COMPLEX SUBUNIT RTF1 DIRECTLY STIMULATES H2B UBIQUITYLATION THROUGH AN INTERACTION WITH RAD6.MOLECULAR CELL. VOL. 64. ISSUE 4. P. 815 -825 37 71% 0

Classes with closest relation at Level 1


Rank Class id link
1 12023 SET8//HISTONE//PR SET7
2 5973 MLL//MLL GENE//11Q23
3 5889 P TEFB//CDK9//RNA POLYMERASE II
4 8082 HISTONE DEMETHYLASE//LSD1//HISTONE DEMETHYLATION
5 5093 HISTONE CHAPERONE//HISTONE VARIANTS//ASF1
6 8607 HISTONE ACETYLTRANSFERASE//GCN5//MOZ
7 12501 SIR COMPLEX//SIR PROTEINS//SIR3
8 5481 ARGININE METHYLATION//PROTEIN ARGININE METHYLTRANSFERASE//PRMT
9 26264 KABUKI SYNDROME//KABUKI MAKE UP SYNDROME//NIIKAWA KUROKI SYNDROME
10 17891 RRP6//MRNP BIOGENESIS METAB//DIS3

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