Class information for:
Level 1: HISTONE DEMETHYLASE//LSD1//HISTONE DEMETHYLATION

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
8082 1295 53.0 94%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
71 3       GENETICS & HEREDITY//CHROMATIN//CELL BIOLOGY 83302
343 2             EZH2//CHROMATIN//POLYCOMB 17754
8082 1                   HISTONE DEMETHYLASE//LSD1//HISTONE DEMETHYLATION 1295

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 HISTONE DEMETHYLASE authKW 2064330 10% 66% 132
2 LSD1 authKW 860432 5% 54% 67
3 HISTONE DEMETHYLATION authKW 664086 3% 72% 39
4 HISTONE LYSINE DEMETHYLASE authKW 498902 2% 92% 23
5 LYSINE SPECIFIC DEMETHYLASE 1 authKW 468295 2% 83% 24
6 MINA53 authKW 306511 1% 100% 13
7 JMJC DOMAIN authKW 305558 1% 72% 18
8 JMJD2A authKW 296251 1% 74% 17
9 JMJD3 authKW 277148 2% 51% 23
10 JMJC authKW 269443 2% 57% 20

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Cell Biology 6214 36% 0% 465
2 Biochemistry & Molecular Biology 3723 45% 0% 587
3 Oncology 1599 20% 0% 255
4 Genetics & Heredity 1118 13% 0% 173
5 Chemistry, Medicinal 563 7% 0% 89
6 Developmental Biology 376 4% 0% 49
7 Biophysics 373 7% 0% 93
8 Cell & Tissue Engineering 107 1% 0% 12
9 Medicine, Research & Experimental 29 3% 0% 39
10 Biochemical Research Methods 20 2% 0% 30

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 OXFORD BIOMED UNIT 105650 1% 41% 11
2 LEVINE SCI B120 70733 0% 100% 3
3 OXFORD INTEGRAT SYST BIOL 55146 2% 9% 25
4 ADV PHARMACEUT TECHNOL 47152 0% 50% 4
5 IRON METAB MOL BIOL 42438 0% 60% 3
6 ZENT KLIN FOR 39290 0% 33% 5
7 EXPT TERATOLCHINESE MINIST EDUC 37720 0% 40% 4
8 STRUCT GENOM CONSORTIUM 36050 3% 4% 36
9 CANC UK LEUKAEMIA BIOL 30311 0% 43% 3
10 LEUKAEMIA BIOL 30311 0% 43% 3

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 EPIGENOMICS 13034 1% 3% 16
2 NATURE STRUCTURAL & MOLECULAR BIOLOGY 2429 1% 1% 15
3 CELL REPORTS 2312 1% 1% 18
4 BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS 2232 1% 1% 10
5 ONCOTARGET 1800 2% 0% 31
6 MEDCHEMCOMM 1729 1% 1% 10
7 MOLECULAR CELL 1696 2% 0% 20
8 GENES & DEVELOPMENT 1498 2% 0% 22
9 CELL RESEARCH 1359 1% 1% 9
10 EPIGENETICS & CHROMATIN 1297 0% 1% 4

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 HISTONE DEMETHYLASE 2064330 10% 66% 132 Search HISTONE+DEMETHYLASE Search HISTONE+DEMETHYLASE
2 LSD1 860432 5% 54% 67 Search LSD1 Search LSD1
3 HISTONE DEMETHYLATION 664086 3% 72% 39 Search HISTONE+DEMETHYLATION Search HISTONE+DEMETHYLATION
4 HISTONE LYSINE DEMETHYLASE 498902 2% 92% 23 Search HISTONE+LYSINE+DEMETHYLASE Search HISTONE+LYSINE+DEMETHYLASE
5 LYSINE SPECIFIC DEMETHYLASE 1 468295 2% 83% 24 Search LYSINE+SPECIFIC+DEMETHYLASE+1 Search LYSINE+SPECIFIC+DEMETHYLASE+1
6 MINA53 306511 1% 100% 13 Search MINA53 Search MINA53
7 JMJC DOMAIN 305558 1% 72% 18 Search JMJC+DOMAIN Search JMJC+DOMAIN
8 JMJD2A 296251 1% 74% 17 Search JMJD2A Search JMJD2A
9 JMJD3 277148 2% 51% 23 Search JMJD3 Search JMJD3
10 JMJC 269443 2% 57% 20 Search JMJC Search JMJC

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 KOOISTRA, SM , HELIN, K , (2012) MOLECULAR MECHANISMS AND POTENTIAL FUNCTIONS OF HISTONE DEMETHYLASES.NATURE REVIEWS MOLECULAR CELL BIOLOGY. VOL. 13. ISSUE 5. P. 297-311 126 64% 233
2 MCALLISTER, TE , ENGLAND, KS , HOPKINSON, RJ , BRENNAN, PE , KAWAMURA, A , SCHOFIELD, CJ , (2016) RECENT PROGRESS IN HISTONE DEMETHYLASE INHIBITORS.JOURNAL OF MEDICINAL CHEMISTRY. VOL. 59. ISSUE 4. P. 1308 -1329 90 78% 11
3 HOJFELDT, JW , AGGER, K , HELIN, K , (2013) HISTONE LYSINE DEMETHYLASES AS TARGETS FOR ANTICANCER THERAPY.NATURE REVIEWS DRUG DISCOVERY. VOL. 12. ISSUE 12. P. 917 -930 117 65% 123
4 SUZUKI, T , MIYATA, N , (2011) LYSINE DEMETHYLASES INHIBITORS.JOURNAL OF MEDICINAL CHEMISTRY. VOL. 54. ISSUE 24. P. 8236 -8250 115 82% 52
5 JOHANSSON, C , TUMBER, A , CHE, KH , CAIN, P , NOWAK, R , GILEADI, C , OPPERMANN, U , (2014) THE ROLES OF JUMONJI-TYPE OXYGENASES IN HUMAN DISEASE.EPIGENOMICS. VOL. 6. ISSUE 1. P. 89 -120 158 50% 32
6 ZHENG, YC , MA, JL , WANG, ZR , LI, JF , JIANG, BL , ZHOU, WJ , SHI, XJ , WANG, XX , ZHAO, W , LIU, HM , (2015) A SYSTEMATIC REVIEW OF HISTONE LYSINE-SPECIFIC DEMETHYLASE 1 AND ITS INHIBITORS.MEDICINAL RESEARCH REVIEWS. VOL. 35. ISSUE 5. P. 1032 -1071 108 68% 16
7 ACCARI, SL , FISHER, PR , (2015) EMERGING ROLES OF JMJC DOMAIN-CONTAINING PROTEINS.INTERNATIONAL REVIEW OF CELL AND MOLECULAR BIOLOGY, VOL 319. VOL. 319. ISSUE . P. 165 -220 118 74% 3
8 HOFFMANN, I , ROATSCH, M , SCHMITT, ML , CARLINO, L , PIPPEL, M , SIPPL, W , JUNG, M , (2012) THE ROLE OF HISTONE DEMETHYLASES IN CANCER THERAPY.MOLECULAR ONCOLOGY. VOL. 6. ISSUE 6. P. 683-703 108 79% 25
9 DIMITROVA, E , TURBERFIELD, AH , KLOSE, RJ , (2015) HISTONE DEMETHYLASES IN CHROMATIN BIOLOGY AND BEYOND.EMBO REPORTS. VOL. 16. ISSUE 12. P. 1620 -1639 132 59% 8
10 BURG, JM , LINK, JE , MORGAN, BS , HELLER, FJ , HARGROVE, AE , MCCAFFERTY, DG , (2015) KDM1 CLASS FLAVIN-DEPENDENT PROTEIN LYSINE DEMETHYLASES.BIOPOLYMERS. VOL. 104. ISSUE 4. P. 213 -246 155 47% 5

Classes with closest relation at Level 1


Rank Class id link
1 12023 SET8//HISTONE//PR SET7
2 31526 ARID3B//JUMONJI//AT RICH INTERACTION DOMAIN
3 14125 USP22//SET1//UBIQUITIN SPECIFIC PROTEASE 22
4 5481 ARGININE METHYLATION//PROTEIN ARGININE METHYLTRANSFERASE//PRMT
5 1710 EZH2//POLYCOMB//BMI 1
6 29445 ZNF217//CTBP//CTBP1
7 36172 TLX//NR2E1//TAILLESS
8 30554 GFI1B//GFI1//ZELLBIOL TUMORFOR
9 19181 NRSF//REST NRSF//NRSF REST
10 27625 METABOLIC MEMORY//IL RISK ASSESSMENT INTERVENT STUDIES//HYPERGLYCEMIC MEMORY

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