Class information for:
Level 1: PRAVASTATIN//HMG COA REDUCTASE INHIBITORS//MEVALONIC ACID

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
9257 1173 32.1 60%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
171 3       MONASCUS//CITRININ//MONASCUS PURPUREUS 58457
419 2             STATINS//EZETIMIBE//SIMVASTATIN 16502
9257 1                   PRAVASTATIN//HMG COA REDUCTASE INHIBITORS//MEVALONIC ACID 1173

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PRAVASTATIN authKW 182629 6% 10% 73
2 HMG COA REDUCTASE INHIBITORS authKW 119610 6% 7% 69
3 MEVALONIC ACID authKW 99937 2% 20% 19
4 SIMVASTATIN authKW 75588 7% 4% 78
5 LOVASTATIN authKW 71820 4% 6% 48
6 CAS 81131 70 6 authKW 58567 0% 75% 3
7 ANDRX S INC address 52060 0% 100% 2
8 LOVASTATIN SIMVASTATIN authKW 52060 0% 100% 2
9 MEVALOTIN R authKW 52060 0% 100% 2
10 SIMVASTATINE authKW 52060 0% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Pharmacology & Pharmacy 3373 32% 0% 380
2 Cardiac & Cardiovascular System 3153 21% 0% 248
3 Peripheral Vascular Diseases 1704 12% 0% 138
4 Medicine, General & Internal 1515 18% 0% 208
5 Medicine, Research & Experimental 365 8% 0% 90
6 Endocrinology & Metabolism 257 7% 0% 81
7 Toxicology 136 4% 0% 47
8 Biochemistry & Molecular Biology 46 10% 0% 119
9 Chemistry, Medicinal 37 2% 0% 29
10 Nutrition & Dietetics 33 2% 0% 24

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ANDRX S INC 52060 0% 100% 2
2 OTC PROD 34706 0% 67% 2
3 ANALYT METAB S SHINJUKU KU 26030 0% 100% 1
4 ANIM SCI TOXICOL S SHINJUKU KU 26030 0% 100% 1
5 BDR AMP CECOS 26030 0% 100% 1
6 BIOL PRINCIPLES SPORT 26030 0% 100% 1
7 BIOL S SHINJUKU KU 26030 0% 100% 1
8 BIOSTAT DISCOVERY EARLY DEV PROJECTS 26030 0% 100% 1
9 BIOSTAT INT 26030 0% 100% 1
10 BOLU IZZET MED 26030 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ATHEROSCLEROSIS 11958 6% 1% 70
2 CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL 11451 4% 1% 46
3 ARTERY 3961 1% 2% 9
4 AMERICAN JOURNAL OF CARDIOLOGY 3936 5% 0% 64
5 JOURNAL OF LIPID RESEARCH 2528 2% 0% 29
6 JOURNAL OF CLINICAL PHARMACOLOGY 1885 2% 0% 20
7 METABOLISM-CLINICAL AND EXPERIMENTAL 1657 2% 0% 24
8 DRUGS 1645 2% 0% 19
9 EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY 1590 2% 0% 21
10 DRUG INVESTIGATION 1423 0% 1% 4

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 PRAVASTATIN 182629 6% 10% 73 Search PRAVASTATIN Search PRAVASTATIN
2 HMG COA REDUCTASE INHIBITORS 119610 6% 7% 69 Search HMG+COA+REDUCTASE+INHIBITORS Search HMG+COA+REDUCTASE+INHIBITORS
3 MEVALONIC ACID 99937 2% 20% 19 Search MEVALONIC+ACID Search MEVALONIC+ACID
4 SIMVASTATIN 75588 7% 4% 78 Search SIMVASTATIN Search SIMVASTATIN
5 LOVASTATIN 71820 4% 6% 48 Search LOVASTATIN Search LOVASTATIN
6 CAS 81131 70 6 58567 0% 75% 3 Search CAS+81131+70+6 Search CAS+81131+70+6
7 LOVASTATIN SIMVASTATIN 52060 0% 100% 2 Search LOVASTATIN+SIMVASTATIN Search LOVASTATIN+SIMVASTATIN
8 MEVALOTIN R 52060 0% 100% 2 Search MEVALOTIN+R Search MEVALOTIN+R
9 SIMVASTATINE 52060 0% 100% 2 Search SIMVASTATINE Search SIMVASTATINE
10 FLUVASTATIN 41036 2% 6% 25 Search FLUVASTATIN Search FLUVASTATIN

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 PLOSKER, GL , WAGSTAFF, AJ , (1996) FLUVASTATIN - A REVIEW OF ITS PHARMACOLOGY AND USE IN THE MANAGEMENT OF HYPERCHOLESTEROLAEMIA.DRUGS. VOL. 51. ISSUE 3. P. 433-459 53 64% 93
2 PLOSKER, GL , MCTAVISH, D , (1995) SIMVASTATIN - A REAPPRAISAL OF ITS PHARMACOLOGY AND THERAPEUTIC EFFICACY IN HYPERCHOLESTEROLEMIA.DRUGS. VOL. 50. ISSUE 2. P. 334-363 74 47% 67
3 TODD, PA , GOA, KL , (1990) SIMVASTATIN - A REVIEW OF ITS PHARMACOLOGICAL PROPERTIES AND THERAPEUTIC POTENTIAL IN HYPERCHOLESTEROLEMIA.DRUGS. VOL. 40. ISSUE 4. P. 583-607 45 82% 151
4 DESAGER, JP , HORSMANS, Y , (1996) CLINICAL PHARMACOKINETICS OF 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE INHIBITORS.CLINICAL PHARMACOKINETICS. VOL. 31. ISSUE 5. P. 348-371 61 46% 140
5 LENNERNAS, H , FAGER, G , (1997) PHARMACODYNAMICS AND PHARMACOKINETICS OF THE HMG-COA REDUCTASE INHIBITORS - SIMILARITIES AND DIFFERENCES.CLINICAL PHARMACOKINETICS. VOL. 32. ISSUE 5. P. 403 -425 42 48% 348
6 MCTAVISH, D , SORKIN, EM , (1991) PRAVASTATIN - A REVIEW OF ITS PHARMACOLOGICAL PROPERTIES AND THERAPEUTIC POTENTIAL IN HYPERCHOLESTEROLEMIA.DRUGS. VOL. 42. ISSUE 1. P. 65-89 36 86% 95
7 GARCIA, MJ , REINOSO, RF , NAVARRO, AS , PROUS, JR , (2003) CLINICAL PHARMACOKINETICS OF STATINS.METHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY. VOL. 25. ISSUE 6. P. 457-481 40 51% 60
8 CORSINI, A , MAGGI, FM , CATAPANO, AL , (1995) PHARMACOLOGY OF COMPETITIVE INHIBITORS OF HMG-COA REDUCTASE.PHARMACOLOGICAL RESEARCH. VOL. 31. ISSUE 1. P. 9-27 61 37% 186
9 DESLYPERE, JP , (1995) THE ROLE OF HMG-COA REDUCTASE INHIBITORS IN THE TREATMENT OF HYPERLIPIDEMIA - A REVIEW OF FLUVASTATIN.CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL. VOL. 56. ISSUE 2. P. 111-128 39 70% 27
10 ENDO, A , (1992) THE DISCOVERY AND DEVELOPMENT OF HMG-COA REDUCTASE INHIBITORS.JOURNAL OF LIPID RESEARCH. VOL. 33. ISSUE 11. P. 1569-1582 33 57% 478

Classes with closest relation at Level 1


Rank Class id link
1 20235 I DEV//SANDOZ DEV SLOVENIA//SCREENING NEW DRUGS
2 18946 ATORVASTATIN CALCIUM//EZETIMIBE//ROSUVASTATIN CALCIUM
3 22615 PROBUCOL//AGI 1067//SUCCINOBUCOL
4 7494 STATINS//RHABDOMYOLYSIS//STATIN INTOLERANCE
5 17284 WHHL RABBIT//WHHLMI RABBIT//PATHOPHARMACOL UNIT
6 10374 FENOFIBRATE//FENOFIBRIC ACID//FIBRATES
7 28605 PARTIAL ILEAL BYPASS//COMBINED HEART LIVER TRANSPLANT//HEART LIVER TRANSPLANTATION
8 413 STATINS//LOW DENSITY LIPOPROTEIN CHOLESTEROL//ATORVASTATIN
9 24822 LIPOPROT UNIT//LIPOPROTEIN KINETICS//USC INRA NUTR ENDOCRINOL
10 23438 BILE ACID SEQUESTRANT//COLESEVELAM HCL//COLESEVELAM

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